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Search results 401 to 488 out of 488 for Ctsl

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0.028s
Type Details Score
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1775122
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 7
Image: g01305 P7
Specimen Label: g01305 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 42
Image: g01305 Adult
Specimen Label: g01305 Adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274122
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287422
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945714
Age: embryonic day 11.5
Image: g01305 E11.5
Specimen Label: g01305 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 7
Image: g01305 P7
Specimen Label: g01305 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 42
Image: g01305 Adult
Specimen Label: g01305 Adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3266022
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1624622
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Note: Expression was not detected in the digestive system.
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1646922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Image: MH961; Specimen C1447
Specimen Label: MH961; Specimen C1447
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736222
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1683322
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1700022
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1832122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Image: MH961; Specimen C1447
Specimen Label: MH961; Specimen C1447
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1876522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Image: MH961; Specimen C1447
Note: Expression was strong in the immune system.
Specimen Label: MH961; Specimen C1447
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 7
Image: g01305 P7
Specimen Label: g01305 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 42
Image: g01305 Adult
Specimen Label: g01305 Adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945714
Age: embryonic day 15.5
Image: g01305 E15.5
Specimen Label: g01305 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 7
Image: g01305 P7
Specimen Label: g01305 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 42
Image: g01305 Adult
Specimen Label: g01305 Adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Image: MH961; Specimen C1447
Specimen Label: MH961; Specimen C1447
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945714
Age: embryonic day 15.5
Image: g01305 E15.5
Specimen Label: g01305 E15.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945714
Age: embryonic day 15.5
Image: g01305 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g01305 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 7
Image: g01305 P7
Specimen Label: g01305 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4882258
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945714
Age: postnatal day 42
Image: g01305 Adult
Specimen Label: g01305 Adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3609674
Assay Type: RNA in situ
Annotation Date: 2006-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3610070
Age: embryonic day 14.5
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3609674
Assay Type: RNA in situ
Annotation Date: 2006-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3610070
Age: embryonic day 16.5
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3724707
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5421365
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: MH961; Specimen C1447
Detected: false
Specimen Num: 1
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication  
First Author: Tutikawa K
Year: 1954
Journal: Annu Rep Natl Inst Genet Jpn
Title: Test for allelism of alopecia periodica and furless in the house mouse
Volume: 5
Pages: 16
UniProt Feature
Begin: 174
Description: Cleavage; by CTSL
Type: site
End: 175
UniProt Feature
Begin: 745
Description: Cleavage; by CTSL
Type: site
End: 753
UniProt Feature
Begin: 641
Description: Cleavage; by CTSL
Type: site
End: 642
UniProt Feature
Begin: 111
Description: Cleavage; by CTSL
Type: site
End: 112
UniProt Feature
Begin: 219
Description: Cleavage; by CTSL
Type: site
End: 220
UniProt Feature
Begin: 216
Description: Cleavage; by CTSL
Type: site
End: 217
UniProt Feature
Begin: 215
Description: Cleavage; by CTSL
Type: site
End: 216
UniProt Feature
Begin: 133
Description: Cleavage; by CTSL
Type: site
End: 134
UniProt Feature
Begin: 112
Description: Cleavage; by CTSL
Type: site
End: 113
UniProt Feature
Begin: 467
Description: Cleavage; by CTSL
Type: site
End: 468
Allele
Name: cathepsin L; targeted mutation 1, Christoph Peters
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: targeted mutation, congenic
Genotype
Symbol: Ctsl/Ctsl
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ctsl/Ctsl<+>
Background: NOD.129P2-Ctsl
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Ctsl/Ctsl
Background: NOD.129P2-Ctsl
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ctsl/Ctsl
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
Allele
Name: cathepsin L; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
Strain
Attribute String: chemically induced mutation, coisogenic, mutant strain
Genotype
Symbol: Ctsl/Ctsl
Background: C57BL/6J-Ctsl
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ctsk/Ctsk Ctsl/Ctsl
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ctsb/Ctsb Ctsl/Ctsl
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Zhao MM
Year: 2021
Journal: Signal Transduct Target Ther
Title: Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development.
Volume: 6
Issue: 1
Pages: 134
Publication  
First Author: Wang Y
Year: 2019
Journal: Life Sci Alliance
Title: Drug screening with human SMN2 reporter identifies SMN protein stabilizers to correct SMA pathology.
Volume: 2
Issue: 2
Publication
First Author: Yamazaki Y
Year: 2010
Journal: Biochem J
Title: The cathepsin L gene is a direct target of FOXO1 in skeletal muscle.
Volume: 427
Issue: 1
Pages: 171-8
Publication
First Author: Yang Z
Year: 2017
Journal: Am J Pathol
Title: Cathepsin H-Mediated Degradation of HDAC4 for Matrix Metalloproteinase Expression in Hepatic Stellate Cells: Implications of Epigenetic Suppression of Matrix Metalloproteinases in Fibrosis through Stabilization of Class IIa Histone Deacetylases.
Volume: 187
Issue: 4
Pages: 781-797