Type |
Details |
Score |
Publication |
First Author: |
Lehner C |
Year: |
2019 |
Journal: |
Dis Model Mech |
Title: |
Tenophages: a novel macrophage-like tendon cell population expressing CX3CL1 and CX3CR1. |
Volume: |
12 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wang SK |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa. |
Volume: |
116 |
Issue: |
20 |
Pages: |
10140-10149 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shimoyama S |
Year: |
2021 |
Journal: |
Eur J Immunol |
Title: |
Ursodeoxycholic acid impairs liver-infiltrating T-cell chemotaxis through IFN-γ and CX3CL1 production in primary biliary cholangitis. |
Volume: |
51 |
Issue: |
6 |
Pages: |
1519-1530 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fu R |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren's syndrome murine model. |
Volume: |
10 |
Issue: |
1 |
Pages: |
1455 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xin H |
Year: |
2005 |
Journal: |
Eur J Immunol |
Title: |
Antitumor immune response by CX3CL1 fractalkine gene transfer depends on both NK and T cells. |
Volume: |
35 |
Issue: |
5 |
Pages: |
1371-80 |
|
•
•
•
•
•
|
Allele |
Name: |
C-X3-C motif chemokine ligand 1; endonuclease-mediated mutation 1, Harwell |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Wojdasiewicz P |
Year: |
2014 |
Journal: |
Arch Immunol Ther Exp (Warsz) |
Title: |
The chemokine CX3CL1 (fractalkine) and its receptor CX3CR1: occurrence and potential role in osteoarthritis. |
Volume: |
62 |
Issue: |
5 |
Pages: |
395-403 |
|
•
•
•
•
•
|
Allele |
Name: |
C-X3-C motif chemokine ligand 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion RA63, GENSAT Project at Rockefeller University |
Allele Type: |
Transgenic |
Attribute String: |
Recombinase |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Steffen Jung |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
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•
•
•
•
•
|
Allele |
Name: |
transgene insertion ES26, Nathaniel Heintz |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, transgenic, congenic |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Steffen Jung |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, mutant strain, congenic |
|
•
•
•
•
•
|
Publication |
First Author: |
Old EA |
Year: |
2014 |
Journal: |
J Clin Invest |
Title: |
Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain. |
Volume: |
124 |
Issue: |
5 |
Pages: |
2023-36 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cx3cl1-cre)RA63Gsat/? |
Background: |
involves: 129S4/SvJaeSor * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Combadiere C |
Year: |
1998 |
Journal: |
J Biol Chem |
Title: |
Identification of CX3CR1. A chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1. |
Volume: |
273 |
Issue: |
37 |
Pages: |
23799-804 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sbrana S |
Year: |
2005 |
Journal: |
Cytometry B Clin Cytom |
Title: |
Post-reperfusion changes of monocyte function in coronary blood after extracorporeal circulation. |
Volume: |
65 |
Issue: |
1 |
Pages: |
14-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Raport CJ |
Year: |
1995 |
Journal: |
Gene |
Title: |
The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues. |
Volume: |
163 |
Issue: |
2 |
Pages: |
295-9 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Chemokines (chemotactic cytokines) are a family of chemoattractant molecules. They attract leukocytes to areas of inflammation and lesions, and play a key role in leukocyte activation. Originally defined as host defense proteins, chemokines are now known to play a much broader biological role []. They have a wide range of effects in many different cell types beyond the immune system, including, for example, various cells of the central nervous system [], and endothelial cells, where they may act as either angiogenic or angiostatic factors [].The chemokine family is divided into four classes based on the number and spacing of their conserved cysteines: 2 Cys residues may be adjacent (the CC family); separated by an intervening residue (the CXC family); have only one of the first two Cys residues (C chemokines); or contain both cysteines, separated by three intervening residues (CX3C chemokines).Chemokines exert their effects by binding to rhodopsin-like G protein-coupled receptors on the surface of cells. Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium ions, which cause a cellular response, including the onset of chemotaxis. There are over fifty distinct chemokines and least 18 human chemokine receptors []. Although the receptors bind only a single class of chemokines, they often bind several members of the same class with high affinity. Chemokine receptors are preferentially expressed on important functional subsets of dendritic cells, monocytes and lymphocytes, including Langerhans cells and T helper cells [, ]. Chemokines and their receptors can also be subclassified into homeostatic leukocyte homing molecules (CXCR4, CXCR5, CCR7, CCR9) versus inflammatory/inducible molecules (CXCR1, CXCR2, CXCR3, CCR1-6, CX3CR1).The only CX3C chemokine identified to date is CX3C chemokine ligand 1 (CX3CL1), also known as fractalkine or neurotactin. It is a transmembrane molecule containing a chemokine domain on an extended mucin-like stalk []. Both the adhesive and chemotactic effects of CX3CL1 are mediated through CX3C chemokine receptor type 1 (CX3CR1), also known as fractalkine receptor []. The receptor is expressed specifically on T cells, natural killer cells and monocytes [, ]. Coupling of the receptor to pertussis toxin-sensitive Gi proteins leads to calcium mobilisation and chemotaxis []. In contrast, adhesion mediated by the receptor is insensitive to pertussis toxin and does not appear to involve calcium mobilisation. CX3CR1 has also been found to act as a weak fusion cofactor for some HIV-1 strains, an interaction that can be potently and specifically blocked by CX3CL1 []. |
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•
•
•
•
•
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Publication |
First Author: |
Mionnet C |
Year: |
2010 |
Journal: |
Nat Med |
Title: |
CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung. |
Volume: |
16 |
Issue: |
11 |
Pages: |
1305-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okuma A |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis. |
Volume: |
8 |
Issue: |
1 |
Pages: |
2050 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lauro C |
Year: |
2014 |
Journal: |
Front Cell Neurosci |
Title: |
Fractalkine/CX3CL1 engages different neuroprotective responses upon selective glutamate receptor overactivation. |
Volume: |
8 |
|
Pages: |
472 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thierry GR |
Year: |
2024 |
Journal: |
Immunity |
Title: |
Non-classical monocytes scavenge the growth factor CSF1 from endothelial cells in the peripheral vascular tree to ensure survival and homeostasis. |
Volume: |
57 |
Issue: |
9 |
Pages: |
2108-2121.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen D |
Year: |
2024 |
Journal: |
Nat Commun |
Title: |
Microglia govern the extinction of acute stress-induced anxiety-like behaviors in male mice. |
Volume: |
15 |
Issue: |
1 |
Pages: |
449 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dorfman MD |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice. |
Volume: |
8 |
|
Pages: |
14556 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishida Y |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration. |
Volume: |
7 |
Issue: |
1 |
Pages: |
16833 |
|
•
•
•
•
•
|
Publication |
First Author: |
Das Sarma J |
Year: |
2020 |
Journal: |
PLoS Pathog |
Title: |
Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection. |
Volume: |
16 |
Issue: |
11 |
Pages: |
e1009034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gesuita L |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Microglia contribute to the postnatal development of cortical somatostatin-positive inhibitory cells and to whisker-evoked cortical activity. |
Volume: |
40 |
Issue: |
7 |
Pages: |
111209 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klapproth E |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. |
Volume: |
13 |
Issue: |
1 |
Pages: |
7648 |
|
•
•
•
•
•
|
Publication |
First Author: |
Striebel JF |
Year: |
2016 |
Journal: |
J Gen Virol |
Title: |
Knockout of fractalkine receptor Cx3cr1 does not alter disease or microglial activation in prion-infected mice. |
Volume: |
97 |
Issue: |
6 |
Pages: |
1481-1487 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peng X |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
CX3CL1-CX3CR1 Interaction Increases the Population of Ly6C(-)CX3CR1(hi) Macrophages Contributing to Unilateral Ureteral Obstruction-Induced Fibrosis. |
Volume: |
195 |
Issue: |
6 |
Pages: |
2797-805 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marelli G |
Year: |
2017 |
Journal: |
Cancer Res |
Title: |
Heme-oxygenase-1 Production by Intestinal CX3CR1+ Macrophages Helps to Resolve Inflammation and Prevents Carcinogenesis. |
Volume: |
77 |
Issue: |
16 |
Pages: |
4472-4485 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ashraf M |
Year: |
2023 |
Journal: |
Cells |
Title: |
Chemokine/ITGA4 Interaction Directs iPSC-Derived Myogenic Progenitor Migration to Injury Sites in Aging Muscle for Regeneration. |
Volume: |
12 |
Issue: |
14 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Jeong D |
Year: |
2021 |
Journal: |
Elife |
Title: |
Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2. |
Volume: |
10 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dobrian AD |
Year: |
2015 |
Journal: |
J Endocrinol |
Title: |
STAT4 contributes to adipose tissue inflammation and atherosclerosis. |
Volume: |
227 |
Issue: |
1 |
Pages: |
13-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cardona AE |
Year: |
2008 |
Journal: |
Blood |
Title: |
Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues. |
Volume: |
112 |
Issue: |
2 |
Pages: |
256-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Herlea-Pana O |
Year: |
2015 |
Journal: |
Cardiovasc Res |
Title: |
Chemokine receptors CXCR2 and CX3CR1 differentially regulate functional responses of bone-marrow endothelial progenitors during atherosclerotic plaque regression. |
Volume: |
106 |
Issue: |
2 |
Pages: |
324-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang H |
Year: |
2015 |
Journal: |
Cell Res |
Title: |
P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy. |
Volume: |
25 |
Issue: |
6 |
Pages: |
674-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roy-Chowdhury E |
Year: |
2021 |
Journal: |
Cardiovasc Res |
Title: |
Human CD16+ monocytes promote a pro-atherosclerotic endothelial cell phenotype via CX3CR1-CX3CL1 interaction. |
Volume: |
117 |
Issue: |
6 |
Pages: |
1510-1522 |
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•
•
•
•
•
|
Publication |
First Author: |
Herbin O |
Year: |
2016 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Monocyte Adhesion and Plaque Recruitment During Atherosclerosis Development Is Regulated by the Adapter Protein Chat-H/SHEP1. |
Volume: |
36 |
Issue: |
9 |
Pages: |
1791-801 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morari J |
Year: |
2014 |
Journal: |
Diabetes |
Title: |
Fractalkine (CX3CL1) is involved in the early activation of hypothalamic inflammation in experimental obesity. |
Volume: |
63 |
Issue: |
11 |
Pages: |
3770-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park H |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
Tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regulates macrophage function. |
Volume: |
289 |
Issue: |
11 |
Pages: |
7897-906 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jung K |
Year: |
2017 |
Journal: |
J Clin Invest |
Title: |
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. |
Volume: |
127 |
Issue: |
8 |
Pages: |
3039-3051 |
|
•
•
•
•
•
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Publication |
First Author: |
Chen M |
Year: |
2012 |
Journal: |
Glia |
Title: |
Para-inflammation-mediated retinal recruitment of bone marrow-derived myeloid cells following whole-body irradiation is CCL2 dependent. |
Volume: |
60 |
Issue: |
5 |
Pages: |
833-42 |
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•
•
•
•
•
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Publication |
First Author: |
Larsen KO |
Year: |
2011 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation. |
Volume: |
301 |
Issue: |
1 |
Pages: |
L50-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu K |
Year: |
2020 |
Journal: |
Front Cell Dev Biol |
Title: |
Local Macrophage-Related Immune Response Is Involved in Cochlear Epithelial Damage in Distinct Gjb2-Related Hereditary Deafness Models. |
Volume: |
8 |
|
Pages: |
597769 |
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•
•
•
•
•
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Publication |
First Author: |
Sarikidi A |
Year: |
2022 |
Journal: |
Biomedicines |
Title: |
Altered Immunomodulatory Responses in the CX3CL1/CX3CR1 Axis Mediated by hMSCs in an Early In Vitro SOD1(G93A) Model of ALS. |
Volume: |
10 |
Issue: |
11 |
|
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•
•
•
•
•
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Publication |
First Author: |
Lubos N |
Year: |
2020 |
Journal: |
Basic Res Cardiol |
Title: |
Inflammation shapes pathogenesis of murine arrhythmogenic cardiomyopathy. |
Volume: |
115 |
Issue: |
4 |
Pages: |
42 |
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•
•
•
•
|
Publication |
First Author: |
Lee S |
Year: |
2020 |
Journal: |
Neuro Oncol |
Title: |
Role of CX3CR1 signaling in malignant transformation of gliomas. |
Volume: |
22 |
Issue: |
10 |
Pages: |
1463-1473 |
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•
•
•
•
|
Publication |
First Author: |
Florentin J |
Year: |
2018 |
Journal: |
J Immunol |
Title: |
Inflammatory Macrophage Expansion in Pulmonary Hypertension Depends upon Mobilization of Blood-Borne Monocytes. |
Volume: |
200 |
Issue: |
10 |
Pages: |
3612-3625 |
|
•
•
•
•
•
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Publication |
First Author: |
Lee YS |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
CX3CR1 differentiates F4/80low monocytes into pro-inflammatory F4/80high macrophages in the liver. |
Volume: |
8 |
Issue: |
1 |
Pages: |
15076 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chaudhri A |
Year: |
2023 |
Journal: |
Front Immunol |
Title: |
The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy. |
Volume: |
14 |
|
Pages: |
1237715 |
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•
•
•
•
•
|
Publication |
First Author: |
Xiong Z |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
CX3CR1+ lung mononuclear phagocytes spatially confined to the interstitium produce TNF-α and IL-6 and promote cigarette smoke-induced emphysema. |
Volume: |
186 |
Issue: |
5 |
Pages: |
3206-14 |
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•
•
•
•
|
Publication |
First Author: |
Rogers JT |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity. |
Volume: |
31 |
Issue: |
45 |
Pages: |
16241-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoshino A |
Year: |
2013 |
Journal: |
J Cell Sci |
Title: |
Roles of chemokine receptor CX3CR1 in maintaining murine bone homeostasis through the regulation of both osteoblasts and osteoclasts. |
Volume: |
126 |
Issue: |
Pt 4 |
Pages: |
1032-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Getzin T |
Year: |
2018 |
Journal: |
EMBO Mol Med |
Title: |
The chemokine receptor CX3CR1 coordinates monocyte recruitment and endothelial regeneration after arterial injury. |
Volume: |
10 |
Issue: |
2 |
Pages: |
151-159 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu Q |
Year: |
2022 |
Journal: |
Front Immunol |
Title: |
Analysis of Mononuclear Phagocytes Disclosed the Establishment Processes of Two Macrophage Subsets in the Adult Murine Kidney. |
Volume: |
13 |
|
Pages: |
805420 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dworzak J |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity. |
Volume: |
10 |
Issue: |
6 |
Pages: |
e0127730 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liang KJ |
Year: |
2009 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling. |
Volume: |
50 |
Issue: |
9 |
Pages: |
4444-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li A |
Year: |
2020 |
Journal: |
Neurobiol Aging |
Title: |
Delivery of exogenous proteins by mesenchymal stem cells attenuates early memory deficits in a murine model of Alzheimer's disease. |
Volume: |
86 |
|
Pages: |
81-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishida Y |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Essential involvement of CX3CR1-mediated signals in the bactericidal host defense during septic peritonitis. |
Volume: |
181 |
Issue: |
6 |
Pages: |
4208-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flamant M |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure. |
Volume: |
11 |
Issue: |
1 |
Pages: |
17982 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ghatnekar A |
Year: |
2013 |
Journal: |
Am J Pathol |
Title: |
Endothelial GATA-6 deficiency promotes pulmonary arterial hypertension. |
Volume: |
182 |
Issue: |
6 |
Pages: |
2391-406 |
|
•
•
•
•
•
|
Publication |
First Author: |
González-Prieto M |
Year: |
2021 |
Journal: |
Glia |
Title: |
Microglial CX3CR1 production increases in Alzheimer's disease and is regulated by noradrenaline. |
Volume: |
69 |
Issue: |
1 |
Pages: |
73-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lonskaya I |
Year: |
2015 |
Journal: |
Neuroscience |
Title: |
Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models. |
Volume: |
304 |
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Pages: |
316-27 |
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Publication |
First Author: |
Lou ZY |
Year: |
2011 |
Journal: |
Mol Immunol |
Title: |
Targeting CB(2) receptor as a neuroinflammatory modulator in experimental autoimmune encephalomyelitis. |
Volume: |
49 |
Issue: |
3 |
Pages: |
453-61 |
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Publication |
First Author: |
Borsig L |
Year: |
2014 |
Journal: |
Oncogene |
Title: |
Inflammatory chemokines and metastasis--tracing the accessory. |
Volume: |
33 |
Issue: |
25 |
Pages: |
3217-24 |
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Publication |
First Author: |
Koenen A |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion. |
Volume: |
12 |
Issue: |
3 |
Pages: |
e0173486 |
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Publication |
First Author: |
Ishida Y |
Year: |
2020 |
Journal: |
J Invest Dermatol |
Title: |
Pivotal Involvement of the CX3CL1-CX3CR1 Axis for the Recruitment of M2 Tumor-Associated Macrophages in Skin Carcinogenesis. |
Volume: |
140 |
Issue: |
10 |
Pages: |
1951-1961.e6 |
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Publication |
First Author: |
Celesti G |
Year: |
2013 |
Journal: |
Br J Cancer |
Title: |
Early expression of the fractalkine receptor CX3CR1 in pancreatic carcinogenesis. |
Volume: |
109 |
Issue: |
9 |
Pages: |
2424-33 |
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Publication |
First Author: |
Barbosa-Silva MC |
Year: |
2022 |
Journal: |
Brain Behav Immun |
Title: |
Mice lacking 5-lipoxygenase display motor deficits associated with cortical and hippocampal synapse abnormalities. |
Volume: |
100 |
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Pages: |
183-193 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
354
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
354
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
354
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
354
 |
Fragment?: |
false |
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Publication |
First Author: |
Zhang D |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator. |
Volume: |
283 |
Issue: |
13 |
Pages: |
8580-90 |
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Publication |
First Author: |
Ebrahimian T |
Year: |
2015 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Absence of Four-and-a-Half LIM Domain Protein 2 Decreases Atherosclerosis in ApoE-/- Mice. |
Volume: |
35 |
Issue: |
5 |
Pages: |
1190-7 |
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Publication |
First Author: |
Doddapattar P |
Year: |
2018 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Endothelial Cell-Derived Von Willebrand Factor, But Not Platelet-Derived, Promotes Atherosclerosis in Apolipoprotein E-Deficient Mice. |
Volume: |
38 |
Issue: |
3 |
Pages: |
520-528 |
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Publication |
First Author: |
Zhang J |
Year: |
2018 |
Journal: |
Transl Neurodegener |
Title: |
Dynamic changes of CX3CL1/CX3CR1 axis during microglial activation and motor neuron loss in the spinal cord of ALS mouse model. |
Volume: |
7 |
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Pages: |
35 |
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Publication |
First Author: |
Castro-Sánchez S |
Year: |
2018 |
Journal: |
Glia |
Title: |
Cx3cr1-deficiency exacerbates alpha-synuclein-A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease. |
Volume: |
66 |
Issue: |
8 |
Pages: |
1752-1762 |
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Publication |
First Author: |
Erreni M |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
The Fractalkine-Receptor Axis Improves Human Colorectal Cancer Prognosis by Limiting Tumor Metastatic Dissemination. |
Volume: |
196 |
Issue: |
2 |
Pages: |
902-14 |
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Publication |
First Author: |
Fang X |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Effects of n-3PUFAs on autophagy and inflammation of hypothalamus and body weight in mice. |
Volume: |
501 |
Issue: |
4 |
Pages: |
927-932 |
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•
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Publication |
First Author: |
García-García E |
Year: |
2023 |
Journal: |
Neurobiol Dis |
Title: |
VPS13A knockdown impairs corticostriatal synaptic plasticity and locomotor behavior in a new mouse model of chorea-acanthocytosis. |
Volume: |
187 |
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Pages: |
106292 |
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Publication |
First Author: |
Reed JR |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Fibroblast growth factor receptor 1 activation in mammary tumor cells promotes macrophage recruitment in a CX3CL1-dependent manner. |
Volume: |
7 |
Issue: |
9 |
Pages: |
e45877 |
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•
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Publication |
First Author: |
Zhao L |
Year: |
2009 |
Journal: |
Exp Eye Res |
Title: |
Retinal vascular repair and neovascularization are not dependent on CX3CR1 signaling in a model of ischemic retinopathy. |
Volume: |
88 |
Issue: |
6 |
Pages: |
1004-13 |
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•
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Publication |
First Author: |
Wang X |
Year: |
2023 |
Journal: |
Front Cell Neurosci |
Title: |
CX3CL1/CX3CR1 signal mediates M1-type microglia and accelerates high-altitude-induced forgetting. |
Volume: |
17 |
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Pages: |
1189348 |
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Publication |
First Author: |
Ding XM |
Year: |
2016 |
Journal: |
Int J Mol Med |
Title: |
Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice. |
Volume: |
37 |
Issue: |
3 |
Pages: |
703-15 |
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Publication |
First Author: |
Ensan S |
Year: |
2016 |
Journal: |
Nat Immunol |
Title: |
Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth. |
Volume: |
17 |
Issue: |
2 |
Pages: |
159-68 |
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Publication |
First Author: |
Gerfen CR |
Year: |
2013 |
Journal: |
Neuron |
Title: |
GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. |
Volume: |
80 |
Issue: |
6 |
Pages: |
1368-83 |
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Publication |
First Author: |
The Jackson Laboratory |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
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Publication |
First Author: |
The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY) |
Year: |
2005 |
Journal: |
Database Download |
Title: |
MGI download of GENSAT transgene data |
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