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Search results 401 to 500 out of 644 for Cyp1a1

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Type Details Score
Genotype
Genotype
Symbol: Cyp1a1/Cyp1a1
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cyp1a1/Cyp1a1
Background: B6.129P2-Cyp1a1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cyp1a1/Cyp1a1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Tg(Cyp1a1-cre)1Dwi/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Orc1/Orc1 Tg(Cyp1a1-cre)1Dwi/?
Background: involves: C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
1314586 | J:477
First Author: Ema M
Year: 1992
Journal: Biochem Biophys Res Commun
Title: cDNA cloning and structure of mouse putative Ah receptor.
Volume: 184
Issue: 1
Pages: 246-53
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Publication
15316568 | J:92919
First Author: Berge G
Year: 2004
Journal: Br J Cancer
Title: Analysis of resveratrol as a lung cancer chemopreventive agent in A/J mice exposed to benzo[a]pyrene.
Volume: 91
Issue: 7
Pages: 1380-3
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Publication
16098658 | J:101897
First Author: Wada S
Year: 2005
Journal: Cancer Lett
Title: Tumor suppressive effects of tocotrienol in vivo and in vitro.
Volume: 229
Issue: 2
Pages: 181-91
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Publication
15198980 | J:90759
First Author: Sansom OJ
Year: 2004
Journal: Genes Dev
Title: Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.
Volume: 18
Issue: 12
Pages: 1385-90
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Publication
23998936 | J:211367
First Author: Hammoudi A
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Proteomic profiling of a mouse model of acute intestinal Apc deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC).
Volume: 440
Issue: 3
Pages: 364-70
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Publication
16116480 | J:104413
First Author: Sansom OJ
Year: 2005
Journal: Oncogene
Title: Apc deficiency predisposes to renal carcinoma in the mouse.
Volume: 24
Issue: 55
Pages: 8205-10
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Publication
23245942 | J:193329
First Author: Azzolin L
Year: 2012
Journal: Cell
Title: Role of TAZ as mediator of Wnt signaling.
Volume: 151
Issue: 7
Pages: 1443-56
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Publication
25347740 | J:224259
First Author: Méniel V
Year: 2015
Journal: Oncogene
Title: Apc and p53 interaction in DNA damage and genomic instability in hepatocytes.
Volume: 34
Issue: 31
Pages: 4118-29
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Publication
22653845 | J:188432
First Author: Moyes LH
Year: 2012
Journal: J Pathol
Title: Activation of Wnt signalling promotes development of dysplasia in Barrett's oesophagus.
Volume: 228
Issue: 1
Pages: 99-112
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Publication
17297472 | J:122904
First Author: Luo F
Year: 2007
Journal: Oncogene
Title: Conditional expression of mutated K-ras accelerates intestinal tumorigenesis in Msh2-deficient mice.
Volume: 26
Issue: 30
Pages: 4415-27
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Publication
24200851 | J:206175
First Author: Marsh Durban V
Year: 2014
Journal: Am J Pathol
Title: Epithelial-specific loss of PTEN results in colorectal juvenile polyp formation and invasive cancer.
Volume: 184
Issue: 1
Pages: 86-91
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Publication
30111642 | J:264375
 
First Author: Bird TG
Year: 2018
Journal: Sci Transl Med
Title: TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.
Volume: 10
Issue: 454
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Publication
25092871 | J:224339
First Author: Tsujita T
Year: 2014
Journal: Mol Cell Biol
Title: Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes.
Volume: 34
Issue: 20
Pages: 3800-16
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Publication
17330052 | J:332744
First Author: Clayton E
Year: 2007
Journal: Nature
Title: A single type of progenitor cell maintains normal epidermis.
Volume: 446
Issue: 7132
Pages: 185-9
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Publication
20346677 | J:159673
First Author: Woodcock SA
Year: 2010
Journal: Curr Biol
Title: Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression.
Volume: 20
Issue: 7
Pages: 669-75
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Publication
21171084 | J:169019
First Author: Luo F
Year: 2011
Journal: J Pathol
Title: Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability.
Volume: 223
Issue: 3
Pages: 390-9
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Publication
20975679 | J:205667
 
First Author: van Es JH
Year: 2010
Journal: Nat Commun
Title: Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors.
Volume: 1
Pages: 18
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Publication
25347472 | J:219415
First Author: Degagné E
Year: 2014
Journal: J Clin Invest
Title: Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs.
Volume: 124
Issue: 12
Pages: 5368-84
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Publication
27342214 | J:281875
First Author: Koppens MA
Year: 2016
Journal: Gastroenterology
Title: Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.
Volume: 151
Issue: 4
Pages: 684-697.e12
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Publication
24814514 | J:219398
First Author: Alcolea MP
Year: 2014
Journal: Nat Cell Biol
Title: Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change.
Volume: 16
Issue: 6
Pages: 615-22
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Strain
MGI:7450919 | B6(Cg)-Gt(ROSA)26Sor<tm1.1(Cyp1a1,Thy1)Stck>/J
Attribute String: mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Cyp1a1-cre)1Dwi/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lgr4/Lgr4 Lgr5/Lgr5 Tg(Cyp1a1-cre)1Dwi/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdx1/Cdx1 Cdx2/Cdx2 Tg(Cyp1a1-cre/ERT)1Dwi/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Stk11/Stk11 Tg(Cyp1a1-cre/ERT)1Dwi/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Tg(Cyp1a1-cre/ERT)1Dwi/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
9083006 | J:39465
First Author: Ma Q
Year: 1997
Journal: J Biol Chem
Title: A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Volume: 272
Issue: 14
Pages: 8878-84
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Publication
27554288 | J:241453
 
First Author: Villa M
Year: 2016
Journal: Nat Commun
Title: The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis.
Volume: 7
Pages: 12652
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Publication
25873311 | J:222716
 
First Author: Lefèvre L
Year: 2015
Journal: Nat Commun
Title: LRH-1 mediates anti-inflammatory and antifungal phenotype of IL-13-activated macrophages through the PPARγ ligand synthesis.
Volume: 6
Pages: 6801
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Publication
15272135 | J:103476
First Author: Tan Z
Year: 2004
Journal: Toxicol Sci
Title: A critical role for MAP kinases in the control of Ah receptor complex activity.
Volume: 82
Issue: 1
Pages: 80-7
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Publication
9461503 | J:46733
 
First Author: Sinclair PR
Year: 1998
Journal: Biochem J
Title: Uroporphyria produced in mice by iron and 5-aminolaevulinic acid does not occur in Cyp1a2(-/-) null mutant mice.
Volume: 330 ( Pt 1)
Pages: 149-53
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Publication
15845371 | J:97596
First Author: Greaves P
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Uroporphyria and hepatic carcinogenesis induced by polychlorinated biphenyls-iron interaction: absence in the Cyp1a2(-/-) knockout mouse.
Volume: 331
Issue: 1
Pages: 147-52
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Publication
15331171 | J:92416
First Author: Ide F
Year: 2004
Journal: Cancer Lett
Title: Skin and salivary gland carcinogenicity of 7,12-dimethylbenz[a]anthracene is equivalent in the presence or absence of aryl hydrocarbon receptor.
Volume: 214
Issue: 1
Pages: 35-41
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Publication
8486527 | J:4680
First Author: Nemoto N
Year: 1993
Journal: Jpn J Cancer Res
Title: Cell-density-dependent expression of Cyp1a2 gene in monolayer-cultured adult mouse hepatocytes.
Volume: 84
Issue: 3
Pages: 265-71
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Publication
8060364 | J:19618
First Author: Villard PH
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung.
Volume: 202
Issue: 3
Pages: 1731-7
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Publication
7733941 | J:24510
First Author: Wanner R
Year: 1995
Journal: Biochem Biophys Res Commun
Title: The differentiation-related upregulation of aryl hydrocarbon receptor transcript levels is suppressed by retinoic acid.
Volume: 209
Issue: 2
Pages: 706-11
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Publication
9244376 | J:41932
First Author: Black VH
Year: 1997
Journal: Arch Biochem Biophys
Title: Molecular cloning of cDNA for guinea pig CYP1A2 comparison with guinea pig CYP1A1.
Volume: 344
Issue: 1
Pages: 11-7
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Publication
15882963 | J:98319
First Author: Iseki M
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Growth suppression of Leydig TM3 cells mediated by aryl hydrocarbon receptor.
Volume: 331
Issue: 4
Pages: 902-8
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Publication
17880909 | J:126932
First Author: Nishiumi S
Year: 2007
Journal: Arch Biochem Biophys
Title: Curcumin suppresses the transformation of an aryl hydrocarbon receptor through its phosphorylation.
Volume: 466
Issue: 2
Pages: 267-73
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Publication
19092804 | J:144216
First Author: Barker N
Year: 2009
Journal: Nature
Title: Crypt stem cells as the cells-of-origin of intestinal cancer.
Volume: 457
Issue: 7229
Pages: 608-11
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Publication
20140021 | J:168177
First Author: Athineos D
Year: 2010
Journal: Oncogene
Title: Myc heterozygosity attenuates the phenotypes of APC deficiency in the small intestine.
Volume: 29
Issue: 17
Pages: 2585-90
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Publication
29426940 | J:262663
First Author: Burke ZD
Year: 2018
Journal: Sci Rep
Title: Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.
Volume: 8
Issue: 1
Pages: 2735
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Publication
17377531 | J:121434
First Author: Sansom OJ
Year: 2007
Journal: Nature
Title: Myc deletion rescues Apc deficiency in the small intestine.
Volume: 446
Issue: 7136
Pages: 676-9
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Publication
22960659 | J:314583
First Author: Feng GJ
Year: 2012
Journal: Gastroenterology
Title: Conditional disruption of Axin1 leads to development of liver tumors in mice.
Volume: 143
Issue: 6
Pages: 1650-9
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Publication
19169280 | J:147589
First Author: Greenow KR
Year: 2009
Journal: Oncogene
Title: Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation.
Volume: 28
Issue: 11
Pages: 1443-53
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Publication
16287996 | J:103412
First Author: Hay T
Year: 2005
Journal: Cancer Res
Title: Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapy.
Volume: 65
Issue: 22
Pages: 10145-8
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Publication
20662002 | J:163599
First Author: Doyle B
Year: 2010
Journal: J Pathol
Title: p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma.
Volume: 222
Issue: 2
Pages: 129-37
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Strain
MGI:6119397 | B6.Cg-Cyp1a1<tm1.1Dwn> Cyp1a2<tm1Dwn> Cyp1b1<tm1Gonz>/H
Attribute String: targeted mutation, deletion, congenic, mutant strain
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Publication
26235622 | J:232896
First Author: Myant K
Year: 2015
Journal: Cell Rep
Title: Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation.
Volume: 12
Issue: 6
Pages: 1019-31
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Publication
23483557 | J:198389
First Author: Marsh V
Year: 2013
Journal: J Pathol
Title: PTEN loss and KRAS activation cooperate in murine biliary tract malignancies.
Volume: 230
Issue: 2
Pages: 165-73
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Publication
31327664 | J:286925
First Author: Fernandez-Antoran D
Year: 2019
Journal: Cell Stem Cell
Title: Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation.
Volume: 25
Issue: 3
Pages: 329-341.e6
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Publication
15959515 | J:99348
First Author: van Es JH
Year: 2005
Journal: Nature
Title: Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
Volume: 435
Issue: 7044
Pages: 959-63
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Publication
25648995 | J:220991
First Author: Zimberlin CD
Year: 2015
Journal: FASEB J
Title: HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis.
Volume: 29
Issue: 5
Pages: 2070-80
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Genotype
Genotype
Symbol: Ascl2/Ascl2 Tg(Cyp1a1-cre)1Dwi/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc Tg(Cyp1a1-cre/ERT)1Dwi/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc<+> Brf1/Brf1 Tg(Cyp1a1-cre)1Dwi/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cyp1a1-cre)1Dwi/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cyp1a1-cre/ERT)1Dwi/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Publication
10639156 | J:59890
First Author: Shimizu Y
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor.
Volume: 97
Issue: 2
Pages: 779-82
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Publication
29726989 | J:265123
First Author: Zhou Y
Year: 2018
Journal: Hum Mol Genet
Title: A splicing mutation in aryl hydrocarbon receptor associated with retinitis pigmentosa.
Volume: 27
Issue: 14
Pages: 2563-2572
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Publication
8148869 | J:17459
First Author: Vasiliou V
Year: 1993
Journal: Pharmacogenetics
Title: Mouse dioxin-inducible cytosolic aldehyde dehydrogenase-3: AHD4 cDNA sequence, genetic mapping, and differences in mRNA levels.
Volume: 3
Issue: 6
Pages: 281-90
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Publication
7704040 | J:22587
First Author: Vasiliou V
Year: 1994
Journal: Pharmacogenetics
Title: Mouse dioxin-inducible NAD(P)H: menadione oxidoreductase: NMO1 cDNA sequence and genetic differences in mRNA levels.
Volume: 4
Issue: 6
Pages: 341-8
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Publication
15258110 | J:210924
First Author: Choudhary D
Year: 2004
Journal: Drug Metab Dispos
Title: Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1.
Volume: 32
Issue: 8
Pages: 840-7
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Publication
23821647 | J:211385
First Author: Nishida CR
Year: 2013
Journal: Mol Pharmacol
Title: Specificity determinants of CYP1B1 estradiol hydroxylation.
Volume: 84
Issue: 3
Pages: 451-8
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Publication
32711051 | J:300992
First Author: Li X
Year: 2020
Journal: Biochim Biophys Acta Mol Basis Dis
Title: 6-Formylindolo (3, 2-b) Carbazole (FICZ)-mediated protection of gut barrier is dependent on T cells in a mouse model of alcohol combined with burn injury.
Volume: 1866
Issue: 11
Pages: 165901
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Publication
28192119 | J:254327
First Author: Shrestha AK
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Leflunomide induces NAD(P)H quinone dehydrogenase 1 enzyme via the aryl hydrocarbon receptor in neonatal mice.
Volume: 485
Issue: 1
Pages: 195-200
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Publication
34979820 | J:331550
First Author: Fehsel K
Year: 2022
Journal: J Psychopharmacol
Title: Activation of the aryl hydrocarbon receptor by clozapine induces preadipocyte differentiation and contributes to endothelial dysfunction.
Volume: 36
Issue: 2
Pages: 191-201
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Publication
25500125 | J:325810
First Author: Ziv-Gal A
Year: 2015
Journal: Toxicol In Vitro
Title: In vitro re-expression of the aryl hydrocarbon receptor (Ahr) in cultured Ahr-deficient mouse antral follicles partially restores the phenotype to that of cultured wild-type mouse follicles.
Volume: 29
Issue: 2
Pages: 329-36
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Publication
15123765 | J:100359
First Author: Jiang W
Year: 2004
Journal: J Pharmacol Exp Ther
Title: Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injury.
Volume: 310
Issue: 2
Pages: 512-9
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Publication
19474220 | J:154083
First Author: Yeager RL
Year: 2009
Journal: Toxicol Sci
Title: Introducing the "TCDD-inducible AhR-Nrf2 gene battery".
Volume: 111
Issue: 2
Pages: 238-46
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Publication
24302727 | J:318623
First Author: Vogel CF
Year: 2014
Journal: J Biol Chem
Title: Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-κB.
Volume: 289
Issue: 3
Pages: 1866-75
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Publication
38069208 | J:343562
 
First Author: Larsen MC
Year: 2023
Journal: Int J Mol Sci
Title: AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors.
Volume: 24
Issue: 23
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Publication
19695277 | J:154000
First Author: Hakk H
Year: 2009
Journal: Toxicol Appl Pharmacol
Title: The effect of dose on 2,3,7,8-TCDD tissue distribution, metabolism and elimination in CYP1A2 (-/-) knockout and C57BL/6N parental strains of mice.
Volume: 241
Issue: 1
Pages: 119-26
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Publication
21507987 | J:175001
First Author: Kang HJ
Year: 2011
Journal: Toxicol Sci
Title: Detoxification: a novel function of BRCA1 in tumor suppression?
Volume: 122
Issue: 1
Pages: 26-37
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Publication
18295293 | J:135671
First Author: Sato S
Year: 2008
Journal: Toxicol Appl Pharmacol
Title: Low-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the aryl hydrocarbon receptor-mediated pathway in mouse liver.
Volume: 229
Issue: 1
Pages: 10-9
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Publication
10051580 | J:53827
First Author: Buters JT
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas.
Volume: 96
Issue: 5
Pages: 1977-82
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Publication
23846873 | J:312084
First Author: Lee C
Year: 2013
Journal: Drug Metab Dispos
Title: Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism.
Volume: 41
Issue: 10
Pages: 1782-6
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Publication
11274970 | J:69554
First Author: Zaccaro C
Year: 2001
Journal: Biochem Pharmacol
Title: Role of cytochrome P450 1A2 in bilirubin degradation Studies in Cyp1a2 (-/-) mutant mice.
Volume: 61
Issue: 7
Pages: 843-9
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Publication
17715397 | J:147684
First Author: Qu X
Year: 2007
Journal: Mol Pharmacol
Title: Disruption of clock gene expression alters responses of the aryl hydrocarbon receptor signaling pathway in the mouse mammary gland.
Volume: 72
Issue: 5
Pages: 1349-58
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Publication
15352028 | J:92561
First Author: Nakatsuru Y
Year: 2004
Journal: Int J Cancer
Title: Dibenzo[A,L]pyrene-induced genotoxic and carcinogenic responses are dramatically suppressed in aryl hydrocarbon receptor-deficient mice.
Volume: 112
Issue: 2
Pages: 179-83
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Publication
12730383 | J:132380
First Author: Moriguchi T
Year: 2003
Journal: Proc Natl Acad Sci U S A
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