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Search results 401 to 500 out of 552 for Ddc

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Type Details Score
Publication
23863478 | J:199302
First Author: Veenvliet JV
Year: 2013
Journal: Development
Title: Specification of dopaminergic subsets involves interplay of En1 and Pitx3.
Volume: 140
Issue: 16
Pages: 3373-84
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Publication
19542360 | J:152424
First Author: Jacob J
Year: 2009
Journal: Development
Title: Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.
Volume: 136
Issue: 14
Pages: 2477-85
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Publication
20080794 | J:155932
First Author: Rose MF
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1.
Volume: 106
Issue: 52
Pages: 22462-7
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Publication
22748019 | J:185964
 
First Author: Sgadò P
Year: 2012
Journal: Neural Dev
Title: The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons.
Volume: 7
Pages: 24
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Publication
10591541 | J:68421
First Author: Jones BC
Year: 1999
Journal: Pharmacogenetics
Title: Quantitative-trait loci analysis of cocaine-related behaviours and neurochemistry.
Volume: 9
Issue: 5
Pages: 607-17
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Publication
19692620 | J:151918
First Author: Jiang H
Year: 2009
Journal: J Neurosci
Title: Subtype specification of GABAergic amacrine cells by the orphan nuclear receptor Nr4a2/Nurr1.
Volume: 29
Issue: 33
Pages: 10449-59
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Publication
34564702 | J:312485
First Author: Zhang Q
Year: 2021
Journal: Cell Death Dis
Title: Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1.
Volume: 12
Issue: 10
Pages: 879
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Publication
23637192 | J:197145
First Author: Stott SR
Year: 2013
Journal: J Neurosci
Title: Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.
Volume: 33
Issue: 18
Pages: 8022-34
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Publication
32499648 | J:294332
First Author: Romanov RA
Year: 2020
Journal: Nature
Title: Molecular design of hypothalamus development.
Volume: 582
Issue: 7811
Pages: 246-252
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Publication
22537018 | J:186263
First Author: Ratzka A
Year: 2012
Journal: J Neurochem
Title: Fibroblast growth factor 2 regulates dopaminergic neuron development in vivo.
Volume: 122
Issue: 1
Pages: 94-105
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Publication
16870172 | J:112887
First Author: Mori AD
Year: 2006
Journal: Dev Biol
Title: Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis.
Volume: 297
Issue: 2
Pages: 566-86
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Publication
26542012 | J:228881
First Author: Gazea M
Year: 2016
Journal: Dev Biol
Title: Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain.
Volume: 409
Issue: 1
Pages: 55-71
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Publication
22278924 | J:182759
First Author: Lahti L
Year: 2012
Journal: Development
Title: Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain.
Volume: 139
Issue: 5
Pages: 894-905
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Publication
22013016 | J:191410
First Author: Ohta Y
Year: 2011
Journal: Diabetes
Title: Convergence of the insulin and serotonin programs in the pancreatic β-cell.
Volume: 60
Issue: 12
Pages: 3208-16
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Publication
21880902 | J:176226
First Author: Yan CH
Year: 2011
Journal: J Neurosci
Title: Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors.
Volume: 31
Issue: 35
Pages: 12413-25
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Publication
28031476 | J:240101
First Author: Lv J
Year: 2017
Journal: J Exp Med
Title: 5-hydroxytryptamine synthesized in the aorta-gonad-mesonephros regulates hematopoietic stem and progenitor cell survival.
Volume: 214
Issue: 2
Pages: 529-545
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Publication
22718343 | J:198880
First Author: Shi M
Year: 2012
Journal: J Cell Sci
Title: Notch-Rbpj signaling is required for the development of noradrenergic neurons in the mouse locus coeruleus.
Volume: 125
Issue: Pt 18
Pages: 4320-32
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Publication
21192082 | J:171106
First Author: Suzuki-Hirano A
Year: 2011
Journal: J Comp Neurol
Title: Dynamic spatiotemporal gene expression in embryonic mouse thalamus.
Volume: 519
Issue: 3
Pages: 528-43
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Publication
30916783 | J:279388
First Author: Weiss AC
Year: 2019
Journal: J Pathol
Title: Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme.
Volume: 248
Issue: 4
Pages: 452-463
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Publication
- | J:103485
     
First Author: Lexicon Genetics Inc
Year: 2005
Journal: MGI Direct Data Submission
Title: NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
O88533
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
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HT Experiment
GSE87595 | Mouse embryonic heart transcriptomic response to Ddc (Ddc_exon1a isoform) ablation
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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GO Term
GO:0036468 | L-dopa decarboxylase activity
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GXD Expression
GXD Expression
Probe: MGI:7548959
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3820117
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7549037
Age: embryonic day 10.5
Image: 4J E10.5
Note: Expression co-localized with Ddc expression in subaortic mesenchymal cells and a subset of hematopoietic cells.
Specimen Label: 4J E10.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7548959
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3820119
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7549037
Age: embryonic day 11.0
Image: 4J E11.5
Note: Expression co-localized with Ddc expression in subaortic mesenchymal cells and a subset of hematopoietic cells.
Specimen Label: 4J E11.5
Detected: true
Specimen Num: 4
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Publication
30759384 | J:286909
First Author: McWilliams IL
Year: 2019
Journal: Cell Rep
Title: Pseudovirus rVSVΔG-ZEBOV-GP Infects Neurons in Retina and CNS, Causing Apoptosis and Neurodegeneration in Neonatal Mice.
Volume: 26
Issue: 7
Pages: 1718-1726.e4
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Publication
39702382 | J:360129
First Author: Sepahpour T
Year: 2024
Journal: NPJ Vaccines
Title: Downregulation of IRF7-mediated type-I interferon response by LmCen(-/-) parasites is necessary for protective immunity.
Volume: 9
Issue: 1
Pages: 250
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Publication
35967447 | J:331765
 
First Author: Manangeeswaran M
Year: 2022
Journal: Front Immunol
Title: BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein.
Volume: 13
Pages: 919815
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Allele
Ddc<em1Smoc> | MGI:7289292
Name: dopa decarboxylase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Tg(Ddc-EGFP)GW36Gsat | MGI:4846989
Name: transgene insertion GW36, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Ddc-cre)SD56Gsat | MGI:5435515
Name: transgene insertion SD56, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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Protein Domain
IPR002668 | CNT_N_dom
Type: Domain
Description: The concentrative nucleoside transporter (CNT) (TC 2.A.41) family includes , which is a purine-specific Na+-nucleoside cotransporter localised to the bile canalicular membrane []. It also includes , a Na+-dependent nucleoside transporter selective for pyrimidine nucleosides and adenosine, which also transports the anti-viral nucleoside analogues AZT and ddC [].This domain lies towards the N terminus of this family of transporters.
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Protein Domain
IPR011657 | CNT_C_dom
Type: Domain
Description: The concentrative nucleoside transporter (CNT) (TC 2.A.41) family includes , which is a purine-specific Na+-nucleoside cotransporter localised to the bile canalicular membrane []. It also includes , a Na+-dependent nucleoside transporter selective for pyrimidine nucleosides and adenosine, which also transports the anti-viral nucleoside analogues AZT and ddC [].This entry covers the C terminus of this family of transporters.
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Strain
MGI:5003719 | STOCK Tg(Ddc-EGFP)GW36Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Strain
MGI:6143677 | B6.FVB(Cg)-Tg(Ddc-cre)SD56Gsat/Mmucd
Attribute String: mutant strain, congenic, transgenic
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Strain
MGI:5435836 | STOCK Tg(Ddc-cre)SD56Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Allele
Ddc<tm1Umon> | MGI:6151137
Name: dopa decarboxylase; targeted mutation 1, Umrao Monani
Allele Type: Targeted
Attribute String: Humanized sequence
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Strain
MGI:6188069 | B6.129S(FVB)-Ddc<tm1Umon>
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:6188071 | FVB.129S(B6)-Ddc<tm1Umon>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6151139 | STOCK Ddc<tm1Umon>/J
Attribute String: targeted mutation, mutant stock
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Genotype
Genotype
Symbol: Ddc/Ddc
Background: involves: 129S/SvEv * C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ddc/Ddc
Background: B6.129S(FVB)-Ddc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ddc/Ddc
Background: FVB.129S(B6)-Ddc
Zygosity: hm
Has Mutant Allele: true
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Publication
8027026 | -
First Author: Huang QQ
Year: 1994
Journal: J Biol Chem
Title: Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein.
Volume: 269
Issue: 27
Pages: 17757-60
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Publication
7775409 | -
First Author: Che M
Year: 1995
Journal: J Biol Chem
Title: Primary structure and functional expression of a cDNA encoding the bile canalicular, purine-specific Na(+)-nucleoside cotransporter.
Volume: 270
Issue: 23
Pages: 13596-9
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Allele
Ddc<em1Gregg> | MGI:7266267
Name: dopa decarboxylase; endonuclease-mediated mutation 1, Christopher Gregg
Allele Type: Endonuclease-mediated
Attribute String: Epitope tag, Reporter
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Allele
Ddc<em2Gregg> | MGI:7266270
Name: dopa decarboxylase; endonuclease-mediated mutation 2, Christopher Gregg
Allele Type: Endonuclease-mediated
Attribute String: Epitope tag, Reporter
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HT Experiment
GSE171581 | Establishment of a dopaminergic neuron purification system in mice for the Parkinson's disease study
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Strain
MGI:7266269 | C57BL/6J-Ddc<em1Gregg>/BnthsJ
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7266271 | C57BL/6J-Ddc<em2Gregg>/BnthsJ
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
1612608 | J:921
First Author: Scherer LJ
Year: 1992
Journal: Genomics
Title: Human dopa decarboxylase: localization to human chromosome 7p11 and characterization of hepatic cDNAs.
Volume: 13
Issue: 2
Pages: 469-71
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Publication
15897263 | J:137517
First Author: Bennett CL
Year: 2005
Journal: J Cell Biol
Title: Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity.
Volume: 169
Issue: 4
Pages: 569-76
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Publication
24198362 | J:204191
First Author: Niu J
Year: 2013
Journal: J Neurosci
Title: Modality-based organization of ascending somatosensory axons in the direct dorsal column pathway.
Volume: 33
Issue: 45
Pages: 17691-709
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Publication
37105975 | J:335771
First Author: Yang SH
Year: 2023
Journal: Nat Commun
Title: Neural mechanism of acute stress regulation by trace aminergic signalling in the lateral habenula in male mice.
Volume: 14
Issue: 1
Pages: 2435
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Publication
25617501 | J:236209
First Author: Szabo S
Year: 2015
Journal: J Hepatol
Title: Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization.
Volume: 62
Issue: 6
Pages: 1357-66
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Publication
24489120 | J:209425
First Author: Kang TH
Year: 2014
Journal: Nucleic Acids Res
Title: Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1.
Volume: 42
Issue: 7
Pages: 4427-34
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Publication
17999954 | J:130600
First Author: Xu Y
Year: 2008
Journal: J Biol Chem
Title: Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria.
Volume: 283
Issue: 3
Pages: 1563-71
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Publication
20713888 | J:163817
First Author: Elnekave M
Year: 2010
Journal: J Immunol
Title: Directly transfected langerin+ dermal dendritic cells potentiate CD8+ T cell responses following intradermal plasmid DNA immunization.
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First Author: Subramanian S
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: Dietary cholesterol worsens adipose tissue macrophage accumulation and atherosclerosis in obese LDL receptor-deficient mice.
Volume: 28
Issue: 4
Pages: 685-91
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First Author: Fickert P
Year: 2010
Journal: Lab Invest
Title: The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice.
Volume: 90
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Year: 2004
Journal: J Neurochem
Title: Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.
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