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Search results 401 to 472 out of 472 for Dusp1

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Type Details Score
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
22897852 | J:191822
First Author: Maraver A
Year: 2012
Journal: Cancer Cell
Title: Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK.
Volume: 22
Issue: 2
Pages: 222-34
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Allele
Dusp1<em2Smoc> | MGI:7289411
Name: dual specificity phosphatase 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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HT Experiment
E-GEOD-3565 | Transcription profiling of spleens from dual specificity phosphatase-1 (DUSP1) deficient and wild type mice to demonstrate a specific regulatory role of DUSP1 on a subset of LPS-induced genes that control the outcome of endotoxin shock
Series Id: GSE3565
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Dusp1<tm2Brv> | MGI:7857101
Name: dual specificity phosphatase 1; targeted mutation 2, Rodrigo Bravo
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Dusp1<em1Smoc> | MGI:7289410
Name: dual specificity phosphatase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Tg(Dusp1-EGFP)GD23Gsat | MGI:4847005
Name: transgene insertion GD23, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5003615 | STOCK Tg(Dusp1-EGFP)GD23Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
18690222 | J:139576
First Author: Ananieva O
Year: 2008
Journal: Nat Immunol
Title: The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
Volume: 9
Issue: 9
Pages: 1028-36
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Publication
32271749 | J:287520
First Author: Goda C
Year: 2020
Journal: PLoS Genet
Title: Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway.
Volume: 16
Issue: 4
Pages: e1008692
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Publication
24367002 | J:208357
First Author: Hirose J
Year: 2014
Journal: J Exp Med
Title: Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5-Dusp axis in the osteoclast.
Volume: 211
Issue: 1
Pages: 153-63
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Protein Domain
IPR020420 | Atypical_DUSP_subfamB
Type: Family
Description: Dual specificity phosphatases (DUSPs) are members of the superfamily of protein tyrosine phosphatases [, ]. They remove the phosphate group from both phospho-tyrosine and phospho-serine/threonine residues. They are structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR [, , ]. They are characterized as VHR- [, ]or Cdc25-like [, ].In general, DUSPs are classified into the following subgroups []:Slingshot phosphatasesPhosphatase of regenerating liver (PRL)Cdc14 phosphatasesPhosphatase and tensin homologue deleted on chromosome 10 (PTEN)-like and myotubularin phosphatasesMitogen-activated protein kinase phosphatases (MKPs)Atypical DUSPsThe atypical DUSPs share a high degree of similarity with the MKP subgroup, but lack the N-terminal regulatory domain, which provides the substrate specificity towards the MAP kinases. These atypical-DUSPs form a heterogeneous group and have in common the presence of a single catalytic PTP domain. VHR was the first characterised member of this subfamily; its crystal structure is known [, ].The function of many atypical DUSPs remains unknown, although some have been related to regulation of MAP kinase pathways [, , ]. VHR has also been related to the control of cell-senescence []. The atypical DUSPs can be subdivided into two groups (termed A and B) on the basis of sequence similarity. Each of these subgroups is characterised by its own distinctive set of motifs, the functions of which are as yet unknown.This entry also includes DUSP1 which does not belong to the atypical DUSP family.
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Publication
16184516 | J:113501
First Author: Hammer M
Year: 2005
Journal: Eur J Immunol
Title: Control of dual-specificity phosphatase-1 expression in activated macrophages by IL-10.
Volume: 35
Issue: 10
Pages: 2991-3001
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Publication
20862286 | J:220946
 
First Author: Factor VM
Year: 2010
Journal: PLoS One
Title: Loss of c-Met disrupts gene expression program required for G2/M progression during liver regeneration in mice.
Volume: 5
Issue: 9
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Publication
16048639 | J:110036
First Author: Krücken J
Year: 2005
Journal: Parasite Immunol
Title: Deletion of LTbetaR augments male susceptibility to Plasmodium chabaudi.
Volume: 27
Issue: 6
Pages: 205-12
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Publication
27220464 | J:246518
First Author: Tiedje C
Year: 2016
Journal: Nucleic Acids Res
Title: The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammation.
Volume: 44
Issue: 15
Pages: 7418-40
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Publication
21562305 | J:175951
First Author: Murray J
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Estrogen-related receptor α regulates skeletal myocyte differentiation via modulation of the ERK MAP kinase pathway.
Volume: 301
Issue: 3
Pages: C630-45
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Publication
23149933 | J:192818
First Author: Kato I
Year: 2013
Journal: Mol Cell Biol
Title: Oxidized DJ-1 inhibits p53 by sequestering p53 from promoters in a DNA-binding affinity-dependent manner.
Volume: 33
Issue: 2
Pages: 340-59
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Publication
35545739 | J:361534
First Author: Yang C
Year: 2022
Journal: Geroscience
Title: Single-cell transcriptomics identifies premature aging features of TERC-deficient mouse brain and bone marrow.
Volume: 44
Issue: 4
Pages: 2139-2155
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Publication
24509876 | J:218630
First Author: Baumgart A
Year: 2015
Journal: Oncogene
Title: Opposing role of Notch1 and Notch2 in a Kras(G12D)-driven murine non-small cell lung cancer model.
Volume: 34
Issue: 5
Pages: 578-88
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Protein
B1AT24
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: true
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Publication
8987394 | -
First Author: Fauman EB
Year: 1996
Journal: Trends Biochem Sci
Title: Structure and function of the protein tyrosine phosphatases.
Volume: 21
Issue: 11
Pages: 413-7
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Publication
1281549 | -
First Author: Ishibashi T
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Expression cloning of a human dual-specificity phosphatase.
Volume: 89
Issue: 24
Pages: 12170-4
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Publication
10224087 | -
First Author: Todd JL
Year: 1999
Journal: J Biol Chem
Title: Extracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathway.
Volume: 274
Issue: 19
Pages: 13271-80
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Publication
11971192 | -
First Author: Todd JL
Year: 2002
Journal: Oncogene
Title: Dual-specificity protein tyrosine phosphatase VHR down-regulates c-Jun N-terminal kinase (JNK).
Volume: 21
Issue: 16
Pages: 2573-83
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Publication
15796912 | -
First Author: Vasudevan SA
Year: 2005
Journal: Biochem Biophys Res Commun
Title: MKP-8, a novel MAPK phosphatase that inhibits p38 kinase.
Volume: 330
Issue: 2
Pages: 511-8
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Publication
16604064 | -
First Author: Rahmouni S
Year: 2006
Journal: Nat Cell Biol
Title: Loss of the VHR dual-specific phosphatase causes cell-cycle arrest and senescence.
Volume: 8
Issue: 5
Pages: 524-31
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Publication
7961745 | -
First Author: Zhou G
Year: 1994
Journal: J Biol Chem
Title: The catalytic role of Cys124 in the dual specificity phosphatase VHR.
Volume: 269
Issue: 45
Pages: 28084-90
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Publication
8154323 | -
 
First Author: Zhang ZY
Year: 1994
Journal: Adv Enzymol Relat Areas Mol Biol
Title: Protein tyrosine phosphatases: mechanism of catalysis and substrate specificity.
Volume: 68
Pages: 1-36
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Publication
7601801 | -
First Author: Cui H
Year: 1995
Journal: J Anim Sci
Title: Cloning and sequencing of a pig cdc25 tyrosine phosphatase cDNA.
Volume: 73
Issue: 2
Pages: 630
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Publication
8701088 | -
 
First Author: Dixon JE
Year: 1996
Journal: Recent Prog Horm Res
Title: Protein tyrosine phosphatases: their roles in signal transduction.
Volume: 51
Pages: 405-14; discussion 415
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Publication
9571625 | -
First Author: Martell KJ
Year: 1998
Journal: Mol Cells
Title: The "VH1-like" dual-specificity protein tyrosine phosphatases.
Volume: 8
Issue: 1
Pages: 2-11
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Publication
17057753 | -
First Author: Tonks NK
Year: 2006
Journal: Nat Rev Mol Cell Biol
Title: Protein tyrosine phosphatases: from genes, to function, to disease.
Volume: 7
Issue: 11
Pages: 833-46
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Publication
15186772 | -
First Author: Alonso A
Year: 2004
Journal: Cell
Title: Protein tyrosine phosphatases in the human genome.
Volume: 117
Issue: 6
Pages: 699-711
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Publication
19228121 | -
First Author: Patterson KI
Year: 2009
Journal: Biochem J
Title: Dual-specificity phosphatases: critical regulators with diverse cellular targets.
Volume: 418
Issue: 3
Pages: 475-89
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Publication
8650541 | -
First Author: Yuvaniyama J
Year: 1996
Journal: Science
Title: Crystal structure of the dual specificity protein phosphatase VHR.
Volume: 272
Issue: 5266
Pages: 1328-31
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Protein
Q9D9D8
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
Q8VE01
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
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Protein
Q9JLY7
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
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Protein
Q8BWD7
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Protein
Q3TLZ7
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
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Protein
Q7TPY1
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
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Protein
Q542U4
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
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Protein
P28563
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Protein
Q3UCQ6
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Protein
A0A494B9K9
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: false
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Protein
Q3U8K3
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: false
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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