|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 401 to 500 out of 503 for Ephb3

<< First    < Previous  |  Next >    Last >>
0.035s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
29912395 | J:320247
First Author: Symmank J
Year: 2019
Journal: Cereb Cortex
Title: The Transcription Factor LHX1 Regulates the Survival and Directed Migration of POA-derived Cortical Interneurons.
Volume: 29
Issue: 4
Pages: 1644-1658
•
•
•
•
•
Publication
38843837 | J:350995
     
First Author: Thowfeequ S
Year: 2024
Journal: Dev Cell
Title: An integrated approach identifies the molecular underpinnings of murine anterior visceral endoderm migration.
•
•
•
•
•
Publication
10601035 | J:58996
First Author: Bertuzzi S
Year: 1999
Journal: Genes Dev
Title: The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain.
Volume: 13
Issue: 23
Pages: 3092-105
•
•
•
•
•
Publication
15778706 | J:98680
First Author: van Es JH
Year: 2005
Journal: Nat Cell Biol
Title: Wnt signalling induces maturation of Paneth cells in intestinal crypts.
Volume: 7
Issue: 4
Pages: 381-6
•
•
•
•
•
Publication
16421308 | J:104532
First Author: Mendes SW
Year: 2006
Journal: J Neurosci
Title: Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain.
Volume: 26
Issue: 3
Pages: 882-92
•
•
•
•
•
Publication
22171039 | J:178901
First Author: Zimmer G
Year: 2011
Journal: J Neurosci
Title: Bidirectional ephrinB3/EphA4 signaling mediates the segregation of medial ganglionic eminence- and preoptic area-derived interneurons in the deep and superficial migratory stream.
Volume: 31
Issue: 50
Pages: 18364-80
•
•
•
•
•
Publication
20616004 | J:162413
First Author: Foster KE
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: EphB-ephrin-B2 interactions are required for thymus migration during organogenesis.
Volume: 107
Issue: 30
Pages: 13414-9
•
•
•
•
•
Publication
16354917 | J:123264
First Author: Quina LA
Year: 2005
Journal: J Neurosci
Title: Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways.
Volume: 25
Issue: 50
Pages: 11595-604
•
•
•
•
•
Publication
25923646 | J:222780
 
First Author: Defourny J
Year: 2015
Journal: Nat Commun
Title: Cochlear supporting cell transdifferentiation and integration into hair cell layers by inhibition of ephrin-B2 signalling.
Volume: 6
Pages: 7017
•
•
•
•
•
Publication
30185604 | J:267455
First Author: Liu XD
Year: 2018
Journal: J Cell Biol
Title: Retrograde regulation of mossy fiber axon targeting and terminal maturation via postsynaptic Lnx1.
Volume: 217
Issue: 11
Pages: 4007-4024
•
•
•
•
•
Publication
21465626 | J:171618
First Author: Saeger BM
Year: 2011
Journal: Dev Dyn
Title: Ephrin/ephrin receptor expression during early stages of mouse inner ear development.
Volume: 240
Issue: 6
Pages: 1578-85
•
•
•
•
•
Publication
16514057 | J:125783
First Author: Bäumer S
Year: 2006
Journal: Blood
Title: Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development.
Volume: 107
Issue: 12
Pages: 4754-62
•
•
•
•
•
Publication
12971893 | J:85573
First Author: Williams SE
Year: 2003
Journal: Neuron
Title: Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm.
Volume: 39
Issue: 6
Pages: 919-35
•
•
•
•
•
Publication
15184386 | J:92247
First Author: Furuyama T
Year: 2004
Journal: J Biol Chem
Title: Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice.
Volume: 279
Issue: 33
Pages: 34741-9
•
•
•
•
•
Publication
16854408 | J:119301
First Author: Kadison SR
Year: 2006
Journal: Dev Biol
Title: The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord.
Volume: 296
Issue: 2
Pages: 499-513
•
•
•
•
•
Publication
35294885 | J:324831
First Author: Lewis AE
Year: 2022
Journal: Cell Rep
Title: Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting.
Volume: 38
Issue: 11
Pages: 110510
•
•
•
•
•
Publication
26839344 | J:240082
First Author: Noh H
Year: 2016
Journal: Development
Title: Proper closure of the optic fissure requires ephrin A5-EphB2-JNK signaling.
Volume: 143
Issue: 3
Pages: 461-72
•
•
•
•
•
Publication
19109910 | J:176643
First Author: Luria V
Year: 2008
Journal: Neuron
Title: Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb.
Volume: 60
Issue: 6
Pages: 1039-53
•
•
•
•
•
Publication
15733672 | J:96550
First Author: Williams TM
Year: 2005
Journal: Dev Biol
Title: Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability.
Volume: 279
Issue: 2
Pages: 462-80
•
•
•
•
•
Publication
21098570 | J:166759
First Author: Villasenor A
Year: 2010
Journal: Development
Title: Epithelial dynamics of pancreatic branching morphogenesis.
Volume: 137
Issue: 24
Pages: 4295-305
•
•
•
•
•
Publication
18651661 | J:139011
First Author: Wilkinson GA
Year: 2008
Journal: Dev Dyn
Title: Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity.
Volume: 237
Issue: 8
Pages: 2220-34
•
•
•
•
•
Publication
28595615 | J:243634
First Author: Laussu J
Year: 2017
Journal: Neural Dev
Title: Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord.
Volume: 12
Issue: 1
Pages: 10
•
•
•
•
•
Publication
19394326 | J:150374
First Author: Garcia MI
Year: 2009
Journal: Dev Biol
Title: LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine.
Volume: 331
Issue: 1
Pages: 58-67
•
•
•
•
•
Publication
9267020 | J:42086
 
Year: 1997
Journal: Cell
Title: Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.
Volume: 90
Issue: 3
Pages: 403-4
•
•
•
•
•
Publication
12684176 | J:83513
First Author: Pickles JO
Year: 2003
Journal: Hear Res
Title: Expression of Ephs and ephrins in developing mouse inner ear.
Volume: 178
Issue: 1-2
Pages: 44-51
•
•
•
•
•
Publication
20112066 | J:162837
First Author: Islam S
Year: 2010
Journal: Dig Dis Sci
Title: Developmental expression of Eph and ephrin family genes in mammalian small intestine.
Volume: 55
Issue: 9
Pages: 2478-88
•
•
•
•
•
Publication
33635162 | J:305040
First Author: Lin L
Year: 2021
Journal: Am J Physiol Heart Circ Physiol
Title: Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism.
Volume: 320
Issue: 4
Pages: H1634-H1645
•
•
•
•
•
Publication
7893599 | J:22208
First Author: Ruiz JC
Year: 1994
Journal: Mech Dev
Title: Identification of novel protein kinases expressed in the myocardium of the developing mouse heart.
Volume: 48
Issue: 3
Pages: 153-64
•
•
•
•
•
Publication
15162501 | J:90276
First Author: Ota MS
Year: 2004
Journal: Dev Dyn
Title: Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells.
Volume: 230
Issue: 2
Pages: 216-28
•
•
•
•
•
Publication
12435358 | J:111207
First Author: Dionne MS
Year: 2002
Journal: Dev Biol
Title: Noggin is required for correct guidance of dorsal root ganglion axons.
Volume: 251
Issue: 2
Pages: 283-93
•
•
•
•
•
Publication
22371266 | J:183770
First Author: Funato N
Year: 2012
Journal: Hum Mol Genet
Title: Tbx1 regulates oral epithelial adhesion and palatal development.
Volume: 21
Issue: 11
Pages: 2524-37
•
•
•
•
•
Publication
24583262 | J:212428
First Author: Raft S
Year: 2014
Journal: Dev Biol
Title: Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear.
Volume: 390
Issue: 1
Pages: 51-67
•
•
•
•
•
Publication
19542359 | J:150346
First Author: North HA
Year: 2009
Journal: Development
Title: Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.
Volume: 136
Issue: 14
Pages: 2467-76
•
•
•
•
•
Publication
12514106 | J:81179
First Author: Trokovic N
Year: 2003
Journal: Genes Dev
Title: Fgfr1 regulates patterning of the pharyngeal region.
Volume: 17
Issue: 1
Pages: 141-53
•
•
•
•
•
Publication
16230531 | J:102106
First Author: Shroyer NF
Year: 2005
Journal: Genes Dev
Title: Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation.
Volume: 19
Issue: 20
Pages: 2412-7
•
•
•
•
•
Publication
12654290 | J:82686
First Author: Liu J
Year: 2003
Journal: Dev Biol
Title: BMP receptor 1b is required for axon guidance and cell survival in the developing retina.
Volume: 256
Issue: 1
Pages: 34-48
•
•
•
•
•
Publication
19571816 | J:157054
First Author: Egawa G
Year: 2009
Journal: J Invest Dermatol
Title: Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis.
Volume: 129
Issue: 10
Pages: 2386-95
•
•
•
•
•
Publication
24336287 | J:207219
First Author: Driskell RR
Year: 2013
Journal: Nature
Title: Distinct fibroblast lineages determine dermal architecture in skin development and repair.
Volume: 504
Issue: 7479
Pages: 277-281
•
•
•
•
•
Publication
35927240 | J:327333
First Author: Yang KY
Year: 2022
Journal: Cell Death Dis
Title: Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.
Volume: 13
Issue: 8
Pages: 674
•
•
•
•
•
Publication
15254900 | J:91730
First Author: Verma-Kurvari S
Year: 2004
Journal: Dev Dyn
Title: Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.
Volume: 230
Issue: 4
Pages: 660-5
•
•
•
•
•
Publication
16446123 | J:105961
First Author: van Eyll JM
Year: 2006
Journal: Gene Expr Patterns
Title: Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.
Volume: 6
Issue: 4
Pages: 353-9
•
•
•
•
•
Publication
7542761 | J:27414
First Author: Sommers CL
Year: 1995
Journal: Oncogene
Title: Murine txk: a protein tyrosine kinase gene regulated by T cell activation.
Volume: 11
Issue: 2
Pages: 245-51
•
•
•
•
•
Publication
27657450 | J:266826
First Author: Sandberg M
Year: 2016
Journal: Neuron
Title: Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.
Volume: 91
Issue: 6
Pages: 1260-1275
•
•
•
•
•
Publication
15073150 | J:89474
First Author: Morikawa Y
Year: 2004
Journal: Development
Title: Extra-embryonic vasculature development is regulated by the transcription factor HAND1.
Volume: 131
Issue: 9
Pages: 2195-204
•
•
•
•
•
Publication
26951610 | J:233532
First Author: Scekic-Zahirovic J
Year: 2016
Journal: EMBO J
Title: Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
Volume: 35
Issue: 10
Pages: 1077-97
•
•
•
•
•
Publication
11439183 | J:70266
First Author: Graef IA
Year: 2001
Journal: Cell
Title: Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.
Volume: 105
Issue: 7
Pages: 863-75
•
•
•
•
•
Publication
19769959 | J:154920
First Author: Zirzow S
Year: 2009
Journal: Dev Biol
Title: Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse.
Volume: 336
Issue: 2
Pages: 145-55
•
•
•
•
•
Publication
31351040 | J:282348
First Author: Dasgupta K
Year: 2019
Journal: Dev Biol
Title: Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.
Volume: 455
Issue: 2
Pages: 434-448
•
•
•
•
•
Publication
32561725 | J:290119
First Author: Soleilhavoup C
Year: 2020
Journal: Nat Commun
Title: Nolz1 expression is required in dopaminergic axon guidance and striatal innervation.
Volume: 11
Issue: 1
Pages: 3111
•
•
•
•
•
Publication
17145500 | J:144660
First Author: Yoshida Y
Year: 2006
Journal: Neuron
Title: PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.
Volume: 52
Issue: 5
Pages: 775-88
•
•
•
•
•
Publication
11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
•
•
•
•
•
Publication
23341629 | J:193822
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
•
•
•
•
•
Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
•
•
•
•
•
Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
•
•
•
•
•
Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
•
•
•
•
•
Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5616095
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5616109
Age: embryonic day 10.5
Specimen Label: not shown EphB3 -/-
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1859757
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5616110
Age: embryonic day 10.5
Specimen Label: not shown EphB3 -/-
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
9707552 | J:49560
First Author: Hock B
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.
Volume: 95
Issue: 17
Pages: 9779-84
•
•
•
•
•
Allele
Ephb3<em1Smoc> | MGI:7645615
Name: Eph receptor B3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5616095
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5616109
Age: embryonic day 10.5
Note: Expression is not altered in mutant embryos.
Specimen Label: not shown EphB2 lacZ/lacZ EphB3 -/-
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1859757
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5616110
Age: embryonic day 10.5
Note: Expression is not altered in mutant embryos.
Specimen Label: not shown EphB2 lacZ/lacZ EphB3 -/-
Detected: true
Specimen Num: 2
•
•
•
•
•
Publication
21266352 | -
First Author: Ji XD
Year: 2011
Journal: Cancer Res
Title: EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration.
Volume: 71
Issue: 3
Pages: 1156-66
•
•
•
•
•
Strain
MGI:6428596 | C57BL/6JSmoc-Ephb3<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Interaction Experiment
Dominguez-Brauer C (2016)
Description: Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.
•
•
•
•
•
Publication
25333284 | J:223549
First Author: Tanaka-Okamoto M
Year: 2014
Journal: PLoS One
Title: Genetic ablation of afadin causes mislocalization and deformation of Paneth cells in the mouse small intestinal epithelium.
Volume: 9
Issue: 10
Pages: e110549
•
•
•
•
•
Protein Domain
IPR034245 | EphB3_rcpt_lig-bd
Type: Domain
Description: This entry represents the ligand-binding domain found in ephrin type-B receptor 3 (EphB3). EphB3 plays a role in cell positioning in the gastrointestinal tract by being preferentially expressed in Paneth cells []. It also has been implicated in early colorectal cancer and early stage squamous cell lung cancer []. Class EphB receptors bind to transmembrane ephrin-B ligands. There are six vertebrate EhpB receptors (EphB1-6), which display promiscuous interactions with three ephrin-B ligands [].Ephrin receptors (EphRs) comprise the largest subfamily of receptor tyrosine kinases (RTKs). EphRs contain a ligand binding domain and two fibronectin repeats extracellularly, a transmembrane segment, and a cytoplasmic tyrosine kinase domain. Binding of the ephrin ligand to EphR requires cell-cell contact since both are anchored to the plasma membrane. The resulting downstream signals occur bidirectionally in both EphR-expressing cells (forward signaling) and ephrin-expressing cells (reverse signaling) [].
•
•
•
•
•
Publication
17906625 | J:130035
First Author: Cortina C
Year: 2007
Journal: Nat Genet
Title: EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.
Volume: 39
Issue: 11
Pages: 1376-83
•
•
•
•
•
Publication
21276420 | J:170939
First Author: Furukawa K
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Smad3 contributes to positioning of proliferating cells in colonic crypts by inducing EphB receptor protein expression.
Volume: 405
Issue: 4
Pages: 521-6
•
•
•
•
•
Publication
34254201 | J:333187
First Author: Montero-HerradĂłn S
Year: 2021
Journal: Histochem Cell Biol
Title: Delayed maturation of thymic epithelium in mice with specific deletion of β-catenin gene in FoxN1 positive cells.
Volume: 156
Issue: 4
Pages: 315-332
•
•
•
•
•
Publication
29058717 | J:252612
First Author: Lagares D
Year: 2017
Journal: Nat Med
Title: ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.
Volume: 23
Issue: 12
Pages: 1405-1415
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom