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Search results 401 to 449 out of 449 for Grb7

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Type Details Score
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
9710451 | J:49436
First Author: Tanaka S
Year: 1998
Journal: J Clin Invest
Title: A novel variant of human Grb7 is associated with invasive esophageal carcinoma.
Volume: 102
Issue: 4
Pages: 821-7
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Pathway
R-MMU-1306955 | GRB7 events in ERBB2 signaling
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Publication
12223469 | -
First Author: Han DC
Year: 2002
Journal: J Biol Chem
Title: EphB1 associates with Grb7 and regulates cell migration.
Volume: 277
Issue: 47
Pages: 45655-61
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Publication
8940081 | -
First Author: Yokote K
Year: 1996
Journal: J Biol Chem
Title: Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors.
Volume: 271
Issue: 48
Pages: 30942-9
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Publication
10664463 | -
First Author: Vayssière B
Year: 2000
Journal: FEBS Lett
Title: Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family.
Volume: 467
Issue: 1
Pages: 91-6
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Publication
10377264 | -
 
First Author: Thömmes K
Year: 1999
Journal: Biochem J
Title: Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor.
Volume: 341 ( Pt 1)
Pages: 211-6
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Publication
12852788 | -
First Author: De Vet EC
Year: 2003
Journal: Biochem J
Title: Adaptor signalling proteins Grb2 and Grb7 are recruited by human G6f, a novel member of the immunoglobulin superfamily encoded in the MHC.
Volume: 375
Issue: Pt 1
Pages: 207-13
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Protein Coding Gene
MGI:95411 | Erbb3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q61526
Organism: Mus musculus/domesticus
Length: 1339  
Fragment?: false
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Protein Coding Gene
MGI:95410 | Erbb2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1098246 | Nrg2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96083 | Nrg1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P70424
Organism: Mus musculus/domesticus
Length: 1256  
Fragment?: false
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Protein
P56974
Organism: Mus musculus/domesticus
Length: 756  
Fragment?: false
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Protein
A0A140LHZ9
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Protein Domain
IPR035034 | Grb14_SH2
Type: Domain
Description: This entry represents the SH2 domain of Grb14. The Grb7 (growth factor receptor-bound 7) family includes Grb7, Grb10, and Grb14. These are adapter proteins mediating signal transduction from multiple cell surface receptors to diverse downstream pathways. They are composed of an N-terminal proline-rich domain, a Ras Associating-like (RA) domain, a Pleckstrin Homology (PH) domain, a PIR (phosphorylated insulin receptor interacting region) domain (also known as the family-specific BPS region), and a C-terminal SH2 domain []. Grb14 binds to various receptor tyrosine kinases (RTKs) under ligand induction. This interaction involves the SH2 and PIR domains [].
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Protein Domain
IPR035035 | Grb14
Type: Family
Description: The Grb7 (growth factor receptor-bound 7) family includes Grb7, Grb10, and Grb14. These are adapter proteins mediating signal transduction from multiple cell surface receptors to diverse downstream pathways. They are composed of an N-terminal proline-rich domain, a Ras Associating-like (RA) domain, a Pleckstrin Homology (PH) domain, a PIR (phosphorylated insulin receptor interacting region) domain (also known as the family-specific BPS region), and a C-terminal SH2 domain []. Grb14 binds to various receptor tyrosine kinases (RTKs) under ligand induction. This interaction involves the SH2 and PIR domains [].
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Publication
14977573 | -
 
First Author: Cariou B
Year: 2004
Journal: Front Biosci
Title: Regulation and functional roles of Grb14.
Volume: 9
Pages: 1626-36
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Protein Domain
IPR035037 | Grb10_SH2
Type: Domain
Description: This entry represents the SH2 domain of Grb10.The Grb7 (growth factor receptor-bound 7) family includes Grb7, Grb10, and Grb14. These are adapter proteins mediating signal transduction from multiple cell surface receptors to diverse downstream pathways. They are composed of an N-terminal proline-rich domain, a Ras Associating-like (RA) domain, a Pleckstrin Homology (PH) domain, a PIR (phosphorylated insulin receptor interacting region) domain (also known as the family-specific BPS region), and a C-terminal SH2 domain []. Grb10 inhibits insulin receptor kinase activity and mediates insulin-stimulated degradation of the insulin receptor []. It binds to the regulatory kinase loop of the insulin receptor (IR) via its SH2 and BPS domains []. Grb10 is directly phosphorylated by mTORC1 and may participate in a feedback inhibition of the phosphatidylinositol 3-kinase (PI3K) and extracellular signal-regulated, mitogen-activated protein kinase (ERK-MAPK) pathways [].
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Protein Domain
IPR035036 | Grb10
Type: Family
Description: The Grb7 (growth factor receptor-bound 7) family includes Grb7, Grb10, and Grb14. These are adapter proteins mediating signal transduction from multiple cell surface receptors to diverse downstream pathways. They are composed of an N-terminal proline-rich domain, a Ras Associating-like (RA) domain, a Pleckstrin Homology (PH) domain, a PIR (phosphorylated insulin receptor interacting region) domain (also known as the family-specific BPS region), and a C-terminal SH2 domain []. Grb10 inhibits insulin receptor kinase activity and mediates insulin-stimulated degradation of the insulin receptor []. It binds to the regulatory kinase loop of the insulin receptor (IR) via its SH2 and BPS domains []. Grb10 is directly phosphorylated by mTORC1 and may participate in a feedback inhibition of the phosphatidylinositol 3-kinase (PI3K) and extracellular signal-regulated, mitogen-activated protein kinase (ERK-MAPK) pathways [].
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Publication
16434550 | -
First Author: Ramos FJ
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: Grb10 mediates insulin-stimulated degradation of the insulin receptor: a mechanism of negative regulation.
Volume: 290
Issue: 6
Pages: E1262-6
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Publication
14766376 | -
 
First Author: Lim MA
Year: 2004
Journal: Front Biosci
Title: Grb10: more than a simple adaptor protein.
Volume: 9
Pages: 387-403
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Publication
21659605 | -
First Author: Yu Y
Year: 2011
Journal: Science
Title: Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling.
Volume: 332
Issue: 6035
Pages: 1322-6
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Publication
7731717 | J:24927
First Author: Ooi J
Year: 1995
Journal: Oncogene
Title: The cloning of Grb10 reveals a new family of SH2 domain proteins.
Volume: 10
Issue: 8
Pages: 1621-30
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Publication
19359342 | J:150032
First Author: Goenaga D
Year: 2009
Journal: Mol Endocrinol
Title: Molecular determinants of Grb14-mediated inhibition of insulin signaling.
Volume: 23
Issue: 7
Pages: 1043-51
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Publication
19071120 | J:142662
First Author: Shiroshima T
Year: 2009
Journal: FEBS Lett
Title: Identification of LRP1B-interacting proteins and inhibition of protein kinase Calpha-phosphorylation of LRP1B by association with PICK1.
Volume: 583
Issue: 1
Pages: 43-8
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Publication
9360986 | J:44023
First Author: Dong LQ
Year: 1997
Journal: J Biol Chem
Title: Cloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma.
Volume: 272
Issue: 46
Pages: 29104-12
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Protein
B1ATS7
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
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Protein
B1ATS8
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: true
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Protein
Q5SUW0
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: true
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Protein
A2ASX3
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
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Protein
Q5SUW3
Organism: Mus musculus/domesticus
Length: 550  
Fragment?: false
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Protein
A2ASX4
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: true
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Protein
Q60760
Organism: Mus musculus/domesticus
Length: 621  
Fragment?: false
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Protein
Q9JLM9
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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Protein
A2ASX2
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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Protein
A2ASX1
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: true
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Protein
Q3TFU9
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: true
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