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Search results 401 to 445 out of 445 for Hap1

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0.01s

Type

Details

Score

Protein

A0A1B0GRL4

Organism:	Mus musculus/domesticus
Length:	241
Fragment?:	true

•

Protein

A0A1B0GSC9

Organism:	Mus musculus/domesticus
Length:	24
Fragment?:	true

•

Protein

Q80VE1

Organism:	Mus musculus/domesticus
Length:	256
Fragment?:	false

•

Publication

7477378 | -

First Author:	Li XJ
Year:	1995
Journal:	Nature
Title:	A huntingtin-associated protein enriched in brain with implications for pathology.
Volume:	378
Issue:	6555
Pages:	398-402

•

Publication

19262167 | -

First Author:	Wu LL
Year:	2009
Journal:	Cell Adh Migr
Title:	Huntingtin associated protein 1 and its functions.
Volume:	3
Issue:	1
Pages:	71-6

•

Publication

27737633 | -

First Author:	Lumsden AL
Year:	2016
Journal:	BMC Evol Biol
Title:	Huntingtin-associated protein 1: Eutherian adaptation from a TRAK-like protein, conserved gene promoter elements, and localization in the human intestine.
Volume:	16
Issue:	1
Pages:	214

•

Protein Domain

IPR006933 | HAP1_N

Type:

Domain

Description:

This entry represents a N-terminal conserved region found in huntingtin-associated protein 1 (HAP1), trafficking Kinesin proteins TRAK1 and TRAK2 (vertebrate), Milton (Drosophila) and T27A3.1 (C. elegans) []. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner [, , ]. It is involved in intracellular trafficking []. HAP1 is also linked to Alzheimer's disease. It regulates amyloid precursor protein subcellular trafficking to the non-amyloidogenic pathway and may negatively regulate Abeta production in neurons [].TRAK1 binds to both kinesin-1 and dynein/dynactin, is prominently localized in axons, and is needed for normal axon outgrowth, whereas TRAK2 predominantly interacts with dynein/dynactin, is more abundantly present in dendrites, and is required for dendritic development [].

•

Genotype

Symbol:	Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Hap1-cre)RE55Gsat/?
Background:	involves: 129S4/SvJaeSor * FVB/N
Zygosity:	cn
Has Mutant Allele:	true

•

Protein

Q6PD31

Organism:	Mus musculus/domesticus
Length:	939
Fragment?:	false

•

Protein

A0A1B0GRS7

Organism:	Mus musculus/domesticus
Length:	606
Fragment?:	false

•

Protein

A2VDH1

Organism:	Mus musculus/domesticus
Length:	664
Fragment?:	true

•

Protein

A0A5F8MPD8

Organism:	Mus musculus/domesticus
Length:	968
Fragment?:	false

•

Protein

Q80TL6

Organism:	Mus musculus/domesticus
Length:	947
Fragment?:	true

•

Protein

A0A1B0GRP1

Organism:	Mus musculus/domesticus
Length:	560
Fragment?:	false

•

Protein

A0A1B0GSQ2

Organism:	Mus musculus/domesticus
Length:	524
Fragment?:	false

•

Protein

A0A1B0GRQ7

Organism:	Mus musculus/domesticus
Length:	731
Fragment?:	false

•

Protein

G3UYW9

Organism:	Mus musculus/domesticus
Length:	672
Fragment?:	false

•

Protein

Q8BZ57

Organism:	Mus musculus/domesticus
Length:	913
Fragment?:	false

•

Protein

Q6P9N8

Organism:	Mus musculus/domesticus
Length:	913
Fragment?:	false

•

Publication

23395375 | J:197848

First Author:	van Spronsen M
Year:	2013
Journal:	Neuron
Title:	TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites.
Volume:	77
Issue:	3
Pages:	485-502

•

Publication

32111832 | J:287088

First Author:	Loregger A
Year:	2020
Journal:	Nat Commun
Title:	Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.
Volume:	11
Issue:	1
Pages:	1128

•

Publication

39388350 | J:358155

First Author:	Dunham TL
Year:	2024
Journal:	Cell Rep
Title:	WWC2 modulates GABA(A)-receptor-mediated synaptic transmission, revealing class-specific mechanisms of synapse regulation by WWC family proteins.
Volume:	43
Issue:	10
Pages:	114841

•

Publication

25074808 | J:335795

First Author:	Firat-Karalar EN
Year:	2014
Journal:	J Cell Sci
Title:	Proteomic analysis of mammalian sperm cells identifies new components of the centrosome.
Volume:	127
Issue:	Pt 19
Pages:	4128-33

•

Publication

33785361 | J:319686

First Author:	Goto H
Year:	2021
Journal:	J Biol Chem
Title:	Direct uptake of sphingosine-1-phosphate independent of phospholipid phosphatases.
Volume:	296

Pages:	100605

•

Publication

32209662 | J:287476

First Author:	Werner ER
Year:	2020
Journal:	Proc Natl Acad Sci U S A
Title:	The TMEM189 gene encodes plasmanylethanolamine desaturase which introduces the characteristic vinyl ether double bond into plasmalogens.
Volume:	117
Issue:	14
Pages:	7792-7798

•

Publication

29927450 | J:308604

First Author:	Geng X
Year:	2018
Journal:	Metallomics
Title:	Role of ZIP8 in regulating cell morphology and NF-κB/Snail2 signaling.
Volume:	10
Issue:	7
Pages:	953-964

•

Publication

11454706 | J:70397

First Author:	Meira LB
Year:	2001
Journal:	Cancer Res
Title:	Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress.
Volume:	61
Issue:	14
Pages:	5552-7

•

Publication

12913073 | J:85070

First Author:	Li H
Year:	2003
Journal:	Hum Mol Genet
Title:	Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release.
Volume:	12
Issue:	16
Pages:	2021-30

•

Publication

28784662 | J:247117

First Author:	Sawai M
Year:	2017
Journal:	J Biol Chem
Title:	The 3-hydroxyacyl-CoA dehydratases HACD1 and HACD2 exhibit functional redundancy and are active in a wide range of fatty acid elongation pathways.
Volume:	292
Issue:	37
Pages:	15538-15551

•

Publication

21832090 | J:176722

First Author:	Mandal M
Year:	2011
Journal:	J Biol Chem
Title:	Impaired alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking and function by mutant huntingtin.
Volume:	286
Issue:	39
Pages:	33719-28

•

Publication

30342059 | J:327032

First Author:	Geng X
Year:	2019
Journal:	Toxicol Appl Pharmacol
Title:	Role of ZIP8 in regulation of cisplatin sensitivity through Bcl-2.
Volume:	362

Pages:	52-58

•

Publication

16738245 | J:128472

First Author:	Rong J
Year:	2006
Journal:	J Neurosci
Title:	Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth.
Volume:	26
Issue:	22
Pages:	6019-30

•

Publication

38091291 | J:360037

First Author:	Pekson R
Year:	2023
Journal:	Proc Natl Acad Sci U S A
Title:	The mitochondrial ATP synthase is a negative regulator of the mitochondrial permeability transition pore.
Volume:	120
Issue:	51
Pages:	e2303713120

•

Publication

28808015 | J:243897

First Author:	Olbrich T
Year:	2017
Journal:	Proc Natl Acad Sci U S A
Title:	A p53-dependent response limits the viability of mammalian haploid cells.
Volume:	114
Issue:	35
Pages:	9367-9372

•

Publication

31872235 | J:286245

First Author:	Gadalla MR
Year:	2020
Journal:	Biochem J
Title:	Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20.
Volume:	477
Issue:	1
Pages:	285-303

•

Publication

9285789 | -

First Author:	Colomer V
Year:	1997
Journal:	Hum Mol Genet
Title:	Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain.
Volume:	6
Issue:	9
Pages:	1519-25

•

Publication

31062249 | J:348502

First Author:	Ting LL
Year:	2019
Journal:	Mol Neurobiol
Title:	Expression of AHI1 Rescues Amyloidogenic Pathology in Alzheimer's Disease Model Cells.
Volume:	56
Issue:	11
Pages:	7572-7582

•

Publication

24360541 | J:203555

First Author:	Gerfen CR
Year:	2013
Journal:	Neuron
Title:	GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits.
Volume:	80
Issue:	6
Pages:	1368-83

•

Publication

12466851 | J:80000

First Author:	Okazaki Y
Year:	2002
Journal:	Nature
Title:	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume:	420
Issue:	6915
Pages:	563-73

•

Publication

11217851 | J:65060

First Author:	Kawai J
Year:	2001
Journal:	Nature
Title:	Functional annotation of a full-length mouse cDNA collection.
Volume:	409
Issue:	6821
Pages:	685-90

•

Publication

11042159 | J:68323

First Author:	Carninci P
Year:	2000
Journal:	Genome Res
Title:	Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume:	10
Issue:	10
Pages:	1617-30

•

Publication

10349636 | J:80645

First Author:	Carninci P
Year:	1999
Journal:	Methods Enzymol
Title:	High-efficiency full-length cDNA cloning.
Volume:	303

Pages:	19-44

•

Publication

11076861 | J:68324

First Author:	Shibata K
Year:	2000
Journal:	Genome Res
Title:	RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume:	10
Issue:	11
Pages:	1757-71

•

Publication

16141073 | -

First Author:	Katayama S
Year:	2005
Journal:	Science
Title:	Antisense transcription in the mammalian transcriptome.
Volume:	309
Issue:	5740
Pages:	1564-6

•

Publication

- | J:100256

First Author:	The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year:	2005
Journal:	Database Download
Title:	MGI download of GENSAT transgene data

•

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Search results 401 to 445 out of 445 for Hap1

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