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Search results 401 to 500 out of 506 for Hdac6

0.032s
Type Details Score
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Wang R
Year: 2019
Journal: J Cell Biol
Title: ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome-lysosome fusion.
Volume: 218
Issue: 1
Pages: 267-284
Publication  
First Author: Kershaw S
Year: 2020
Journal: J Cell Sci
Title: Glucocorticoids rapidly inhibit cell migration through a novel, non-transcriptional HDAC6 pathway.
Volume: 133
Issue: 11
Publication
First Author: Bobrowicz M
Year: 2017
Journal: Blood
Title: HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies.
Volume: 130
Issue: 14
Pages: 1628-1638
Publication
First Author: Osseni A
Year: 2022
Journal: Nat Commun
Title: Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation.
Volume: 13
Issue: 1
Pages: 7108
Interaction Experiment
Description: Tau--an inhibitor of deacetylase HDAC6 function.
Interaction Experiment
Description: Hdac6 regulates Tip60-p400 function in stem cells.
Publication
First Author: Phipps AJ
Year: 2024
Journal: Heliyon
Title: HDAC6 inhibition as a mechanism to prevent neurodegeneration in the mSOD1(G93A) mouse model of ALS.
Volume: 10
Issue: 14
Pages: e34587
Publication
First Author: Karnam K
Year: 2020
Journal: Biochim Biophys Acta Mol Basis Dis
Title: HDAC6 inhibitor accelerates wound healing by inhibiting tubulin mediated IL-1β secretion in diabetic mice.
Volume: 1866
Issue: 11
Pages: 165903
Publication
First Author: Nelson HA
Year: 2024
Journal: J Biol Chem
Title: MAP3K4 signaling regulates HDAC6 and TRAF4 coexpression and stabilization in trophoblast stem cells.
Volume: 301
Issue: 2
Pages: 108116
Publication  
First Author: Zhang J
Year: 2022
Journal: Brain Behav Immun
Title: An HDAC6 inhibitor reverses chemotherapy-induced mechanical hypersensitivity via an IL-10 and macrophage dependent pathway.
Volume: 100
Pages: 287-296
Publication
First Author: Yang J
Year: 2022
Journal: Sci Transl Med
Title: Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy.
Volume: 14
Issue: 652
Pages: eabl5654
Allele
Name: histone deacetylase 6; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Moufarrij S
Year: 2020
Journal: Sci Rep
Title: Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer.
Volume: 10
Issue: 1
Pages: 3470
Protein
Organism: Mus musculus/domesticus
Length: 1149  
Fragment?: false
Interaction Experiment
Description: HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.
Publication
First Author: Fusco C
Year: 2014
Journal: Cell Signal
Title: HDAC6 mediates the acetylation of TRIM50.
Volume: 26
Issue: 2
Pages: 363-9
Allele
Name: histone deacetylase 6; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Interaction Experiment
Description: HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience.
Interaction Experiment
Description: HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates.
Interaction Experiment
Description: HDAC6 regulates sensitivity to cell death in response to stress and post-stress recovery.
Interaction Experiment
Description: Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex.
Interaction Experiment
Description: Rescue of CAMDI deletion-induced delayed radial migration and psychiatric behaviors by HDAC6 inhibitor.
Interaction Experiment
Description: HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Publication
First Author: Kovacs JJ
Year: 2005
Journal: Mol Cell
Title: HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.
Volume: 18
Issue: 5
Pages: 601-7
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Publication
First Author: Ryu HW
Year: 2017
Journal: Cell Stress Chaperones
Title: HDAC6 regulates sensitivity to cell death in response to stress and post-stress recovery.
Volume: 22
Issue: 2
Pages: 253-261
Publication
First Author: Salemi LM
Year: 2017
Journal: BMC Cancer
Title: Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex.
Volume: 17
Issue: 1
Pages: 460
DO Term
Publication
First Author: Tala
Year: 2014
Journal: PLoS One
Title: Microtubule stabilization by Mdp3 is partially attributed to its modulation of HDAC6 in addition to its association with tubulin and microtubules.
Volume: 9
Issue: 3
Pages: e90932
Publication
First Author: Buglio D
Year: 2011
Journal: Blood
Title: HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma.
Volume: 117
Issue: 10
Pages: 2910-7
Publication
First Author: Gao L
Year: 2002
Journal: J Biol Chem
Title: Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family.
Volume: 277
Issue: 28
Pages: 25748-55
Publication
First Author: Voelter-Mahlknecht S
Year: 2005
Journal: Int J Mol Med
Title: Chromosomal organization and localization of the novel class IV human histone deacetylase 11 gene.
Volume: 16
Issue: 4
Pages: 589-98
Protein Domain
Type: Domain
Description: This entry represents a domain found in class IV histone deacetylases (), also known as histone deacetylase 11 (HDAC11) [, ]. This class includes animal HDAC11, plant HDA2 and related bacterial deacetylases. Enzymes in this subfamily participate in regulation of a number of different processes through protein modification (deacetylation) []. HDAC11 and HDAC6 interact with each other in the cytoplasm and nuclei of APCs (antigen presenting cells) and are recruited to the IL-10 gene promoter to regulate its transcriptional activity [].In mammals, HDAC11 proteins are known to be involved in progression of various tumours. HDAC11 plays an essential role in regulating OX40 ligand (OX40L) expression in Hodgkin lymphoma (HL); selective inhibition of HDAC11 expression significantly up-regulates OX40L and induces apoptosis in HL cell lines. Thus, inhibition of HDAC11 could be a therapeutic drug option for antitumor immune response in HL patients [].
Publication
First Author: Loktev AV
Year: 2008
Journal: Dev Cell
Title: A BBSome subunit links ciliogenesis, microtubule stability, and acetylation.
Volume: 15
Issue: 6
Pages: 854-65
Publication  
First Author: Eira J
Year: 2021
Journal: Front Cell Dev Biol
Title: Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation.
Volume: 9
Pages: 747699
Publication
First Author: Patel H
Year: 2016
Journal: J Mol Cell Biol
Title: Kindlin1 regulates microtubule function to ensure normal mitosis.
Volume: 8
Issue: 4
Pages: 338-48
Publication  
First Author: Lebrun N
Year: 2021
Journal: Brain Res
Title: HDAC inhibitor ameliorates behavioral deficits in Mecp2308/y mouse model of Rett syndrome.
Volume: 1772
Pages: 147670
Publication
First Author: Tseng JH
Year: 2021
Journal: Cell Rep
Title: Tau seeds are subject to aberrant modifications resulting in distinct signatures.
Volume: 35
Issue: 4
Pages: 109037
Publication
First Author: Yanda MK
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: An inhibitor of histone deacetylase 6 activity, ACY-1215, reduces cAMP and cyst growth in polycystic kidney disease.
Volume: 313
Issue: 4
Pages: F997-F1004
Publication
First Author: Villar-Pazos S
Year: 2023
Journal: Nat Commun
Title: Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy.
Volume: 14
Issue: 1
Pages: 6547
Publication    
First Author: Gopalan J
Year: 2021
Journal: Elife
Title: Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis.
Volume: 10
Publication
First Author: Li Y
Year: 2013
Journal: FEBS J
Title: Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processes.
Volume: 280
Issue: 3
Pages: 775-93
Publication
First Author: Chang J
Year: 2009
Journal: J Cell Sci
Title: The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons.
Volume: 122
Issue: Pt 13
Pages: 2274-82
Publication
First Author: Balasubramanian A
Year: 2014
Journal: FASEB J
Title: Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.
Volume: 28
Issue: 7
Pages: 2955-69
Publication
First Author: Heim CE
Year: 2020
Journal: Nat Microbiol
Title: Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection.
Volume: 5
Issue: 10
Pages: 1271-1284
Publication
First Author: Adeegbe DO
Year: 2017
Journal: Cancer Discov
Title: Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-Small Cell Lung Cancer.
Volume: 7
Issue: 8
Pages: 852-867
Publication
First Author: Fan SJ
Year: 2018
Journal: Cell Death Dis
Title: The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer's disease model.
Volume: 9
Issue: 6
Pages: 655
Publication
First Author: Frasca A
Year: 2020
Journal: EMBO Mol Med
Title: MECP2 mutations affect ciliogenesis: a novel perspective for Rett syndrome and related disorders.
Volume: 12
Issue: 6
Pages: e10270
Publication  
First Author: Xu X
Year: 2014
Journal: Front Cell Neurosci
Title: A selective histone deacetylase-6 inhibitor improves BDNF trafficking in hippocampal neurons from Mecp2 knockout mice: implications for Rett syndrome.
Volume: 8
Pages: 68
Publication  
First Author: Xu W
Year: 2019
Journal: Development
Title: Paxillin-dependent regulation of apical-basal polarity in mammary gland morphogenesis.
Volume: 146
Issue: 9
Publication
First Author: Torres OV
Year: 2016
Journal: Neurotox Res
Title: An Acute Methamphetamine Injection Downregulates the Expression of Several Histone Deacetylases (HDACs) in the Mouse Nucleus Accumbens: Potential Regulatory Role of HDAC2 Expression.
Volume: 30
Issue: 1
Pages: 32-40
Publication
First Author: Darlyuk-Saadon I
Year: 2012
Journal: Biochim Biophys Acta
Title: The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter.
Volume: 1819
Issue: 11-12
Pages: 1142-53
Publication
First Author: Yang Y
Year: 2014
Journal: Cell Res
Title: CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Volume: 24
Issue: 11
Pages: 1342-53
Publication  
First Author: Xiao H
Year: 2023
Journal: Biochem Biophys Res Commun
Title: LIPUS accelerates bone regeneration via HDAC6-mediated ciliogenesis.
Volume: 641
Pages: 34-41
Publication  
First Author: Sanbe A
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Modification of cardiac disease by transgenically altered histone deacetylase 6.
Volume: 631
Pages: 48-54
Publication
First Author: Zundell JA
Year: 2021
Journal: Cancer Res
Title: Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers.
Volume: 81
Issue: 20
Pages: 5325-5335
Publication
First Author: McLendon PM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy.
Volume: 111
Issue: 48
Pages: E5178-86
Publication
First Author: Stilling S
Year: 2022
Journal: Commun Biol
Title: PIP2 determines length and stability of primary cilia by balancing membrane turnovers.
Volume: 5
Issue: 1
Pages: 93
Publication  
First Author: Baur K
Year: 2024
Journal: Life Sci Alliance
Title: GDF15 controls primary cilia morphology and function thereby affecting progenitor proliferation.
Volume: 7
Issue: 7
Publication
First Author: Sun S
Year: 2024
Journal: Nat Commun
Title: Metabolic regulation of cytoskeleton functions by HDAC6-catalyzed α-tubulin lactylation.
Volume: 15
Issue: 1
Pages: 8377
Publication
First Author: Steinhäuser K
Year: 2017
Journal: Oncogene
Title: Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics.
Volume: 36
Issue: 15
Pages: 2146-2159
Publication
First Author: Kim M
Year: 2023
Journal: Korean J Physiol Pharmacol
Title: PSME4 determines mesenchymal stem cell fate towards cardiac commitment through YAP1 degradation.
Volume: 27
Issue: 4
Pages: 407-416
Publication  
First Author: Kim YS
Year: 2022
Journal: Pharmaceutics
Title: PSME4 Degrades Acetylated YAP1 in the Nucleus of Mesenchymal Stem Cells.
Volume: 14
Issue: 8
Publication  
First Author: Wildung M
Year: 2022
Journal: Int J Mol Sci
Title: miR449 Protects Airway Regeneration by Controlling AURKA/HDAC6-Mediated Ciliary Disassembly.
Volume: 23
Issue: 14
Publication
First Author: Kozyreva VK
Year: 2014
Journal: Mol Cancer Res
Title: NEDD9 regulates actin dynamics through cortactin deacetylation in an AURKA/HDAC6-dependent manner.
Volume: 12
Issue: 5
Pages: 681-93
Publication
First Author: Jacob LS
Year: 2011
Journal: Sci Signal
Title: Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling.
Volume: 4
Issue: 157
Pages: ra4
Publication
First Author: Prodromou NV
Year: 2012
Journal: J Cell Sci
Title: Heat shock induces rapid resorption of primary cilia.
Volume: 125
Issue: Pt 18
Pages: 4297-305
Publication
First Author: Ferrer I
Year: 2014
Journal: J Pathol
Title: Tubers from patients with tuberous sclerosis complex are characterized by changes in microtubule biology through ROCK2 signalling.
Volume: 233
Issue: 3
Pages: 247-57
Publication
First Author: Chen J
Year: 2019
Journal: J Biol Chem
Title: The histone deacetylase inhibitor tubacin mitigates endothelial dysfunction by up-regulating the expression of endothelial nitric oxide synthase.
Volume: 294
Issue: 51
Pages: 19565-19576
Publication
First Author: Wu JY
Year: 2018
Journal: J Biol Chem
Title: Histone deacetylase 6 (HDAC6) deacetylates extracellular signal-regulated kinase 1 (ERK1) and thereby stimulates ERK1 activity.
Volume: 293
Issue: 6
Pages: 1976-1993
Publication
First Author: Riolo MT
Year: 2012
Journal: J Biol Chem
Title: Histone deacetylase 6 (HDAC6) deacetylates survivin for its nuclear export in breast cancer.
Volume: 287
Issue: 14
Pages: 10885-93
Publication  
First Author: Kai H
Year: 2021
Journal: Front Cell Dev Biol
Title: LncRNA NORAD Promotes Vascular Endothelial Cell Injury and Atherosclerosis Through Suppressing VEGF Gene Transcription via Enhancing H3K9 Deacetylation by Recruiting HDAC6.
Volume: 9
Pages: 701628
Publication  
First Author: Cosín-Tomás M
Year: 2014
Journal: Front Aging Neurosci
Title: Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise.
Volume: 6
Pages: 51
Publication
First Author: Cebotaru V
Year: 2014
Journal: J Biol Chem
Title: Polycystin-1 negatively regulates Polycystin-2 expression via the aggresome/autophagosome pathway.
Volume: 289
Issue: 10
Pages: 6404-6414
Publication
First Author: Yao Q
Year: 2021
Journal: FASEB J
Title: Polycystin-1 dependent regulation of polycystin-2 via GRP94, a member of HSP90 family that resides in the endoplasmic reticulum.
Volume: 35
Issue: 10
Pages: e21865
Publication  
First Author: Hsieh TH
Year: 2023
Journal: Biomed Pharmacother
Title: Vorinostat decrease M2 macrophage polarization through ARID1A(6488delG)/HDAC6/IL-10 signaling pathway in endometriosis-associated ovarian carcinoma.
Volume: 161
Pages: 114500