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Search results 401 to 500 out of 519 for Hsf1

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Type Details Score
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Dayalan Naidu S
Year: 2017
Journal: Sci Rep
Title: Transcription factors NRF2 and HSF1 have opposing functions in autophagy.
Volume: 7
Issue: 1
Pages: 11023
Publication
First Author: Liu W
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Neuroprotective Effects of HSF1 in Retinal Ischemia-Reperfusion Injury.
Volume: 60
Issue: 4
Pages: 965-977
Publication  
First Author: Gomez-Pastor R
Year: 2017
Journal: Nat Commun
Title: Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease.
Volume: 8
Pages: 14405
Publication
First Author: Santagata S
Year: 2013
Journal: Science
Title: Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state.
Volume: 341
Issue: 6143
Pages: 1238303
Publication
First Author: Kubota H
Year: 1999
Journal: FEBS Lett
Title: Transcriptional activation of mouse cytosolic chaperonin CCT subunit genes by heat shock factors HSF1 and HSF2.
Volume: 461
Issue: 1-2
Pages: 125-9
Publication
First Author: Waldhart AN
Year: 2023
Journal: iScience
Title: Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP.
Volume: 26
Issue: 5
Pages: 106538
Publication
First Author: Green M
Year: 1995
Journal: Mol Cell Biol
Title: A heat shock-responsive domain of human HSF1 that regulates transcription activation domain function.
Volume: 15
Issue: 6
Pages: 3354-62
Publication  
First Author: Tan K
Year: 2015
Journal: Nat Commun
Title: Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 transcriptional activity.
Volume: 6
Pages: 6580
HT Experiment
Series Id: GSE26240
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Isermann T
Year: 2021
Journal: Nat Commun
Title: Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity.
Volume: 12
Issue: 1
Pages: 4019
Publication  
First Author: Schulz R
Year: 2014
Journal: Cell Death Dis
Title: HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer.
Volume: 5
Pages: e980
Publication
First Author: Wang X
Year: 2014
Journal: J Neurosci
Title: The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice.
Volume: 34
Issue: 21
Pages: 7253-65
Publication
First Author: Jin YH
Year: 2015
Journal: Biochem Biophys Res Commun
Title: BAG3 affects the nucleocytoplasmic shuttling of HSF1 upon heat stress.
Volume: 464
Issue: 2
Pages: 561-7
Publication
First Author: Zou Y
Year: 2003
Journal: Circulation
Title: Heat shock transcription factor 1 protects cardiomyocytes from ischemia/reperfusion injury.
Volume: 108
Issue: 24
Pages: 3024-30
Allele
Name: transgene insertion 1, Akira Nakai
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Tanaka K
Year: 2010
Journal: Biochem Pharmacol
Title: Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice.
Volume: 80
Issue: 6
Pages: 920-31
Genotype
Symbol: Tg(ACTB-HSF1)1Anak/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Chen Z
Year: 2017
Journal: Oncotarget
Title: FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice.
Volume: 8
Issue: 62
Pages: 106038-106049
Publication
First Author: Raitt DC
Year: 2000
Journal: Mol Biol Cell
Title: The Skn7 response regulator of Saccharomyces cerevisiae interacts with Hsf1 in vivo and is required for the induction of heat shock genes by oxidative stress.
Volume: 11
Issue: 7
Pages: 2335-47
Genotype
Symbol: Hsf1/Hsf1 Tg(ACTB-HSF1)1Anak/?
Background: involves: C57BL/6 * CBA * ICR
Zygosity: cx
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1149  
Fragment?: false
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: false
Publication
First Author: Sheldon LA
Year: 1993
Journal: Genes Dev
Title: Hydrophobic coiled-coil domains regulate the subcellular localization of human heat shock factor 2.
Volume: 7
Issue: 8
Pages: 1549-58
Publication
First Author: Abane R
Year: 2010
Journal: FEBS J
Title: Roles of heat shock factors in gametogenesis and development.
Volume: 277
Issue: 20
Pages: 4150-72
Publication
First Author: Sakurai H
Year: 2010
Journal: FEBS J
Title: Novel aspects of heat shock factors: DNA recognition, chromatin modulation and gene expression.
Volume: 277
Issue: 20
Pages: 4140-9
Publication
First Author: Sandqvist A
Year: 2009
Journal: Mol Biol Cell
Title: Heterotrimerization of heat-shock factors 1 and 2 provides a transcriptional switch in response to distinct stimuli.
Volume: 20
Issue: 5
Pages: 1340-7
Protein Domain
Type: Family
Description: Four heat shock factor proteins (HSFs) have been identified in vertebrates (HSF1-4) []. HSF2 is localised to the cytoplasm duringnormal growth and moves to the nucleus upon activation [], where it specifically binds heat shock promoter elements (HSE) and activates transcription. HSF2 may not be directly involved in the stress response, but rather in cell differentiation and development [, ]. HSF1 and HSF2 can form heterotrimers, which could be a mechanism regulating transcription [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
Publication
First Author: Nakai A
Year: 1999
Journal: Cell Stress Chaperones
Title: New aspects in the vertebrate heat shock factor system: Hsf3 and Hsf4.
Volume: 4
Issue: 2
Pages: 86-93
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
Publication
First Author: Solimini NL
Year: 2007
Journal: Cell
Title: Non-oncogene addiction and the stress phenotype of cancer cells.
Volume: 130
Issue: 6
Pages: 986-8
Publication
First Author: Wooten MW
Year: 1999
Journal: Cell Death Differ
Title: Overexpression of atypical PKC in PC12 cells enhances NGF-responsiveness and survival through an NF-kappaB dependent pathway.
Volume: 6
Issue: 8
Pages: 753-64
Publication
First Author: Suzuki A
Year: 2001
Journal: J Cell Biol
Title: Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures.
Volume: 152
Issue: 6
Pages: 1183-96
Publication
First Author: Boellmann F
Year: 2010
Journal: PLoS One
Title: The identification of protein kinase C iota as a regulator of the Mammalian heat shock response using functional genomic screens.
Volume: 5
Issue: 7
Pages: e11850
Publication
First Author: Regala RP
Year: 2009
Journal: Cancer Res
Title: Atypical protein kinase C{iota} is required for bronchioalveolar stem cell expansion and lung tumorigenesis.
Volume: 69
Issue: 19
Pages: 7603-11
Publication
First Author: Kikuchi K
Year: 2013
Journal: Oncogene
Title: Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma.
Volume: 32
Issue: 3
Pages: 286-95
Publication
First Author: Ohno S
Year: 2001
Journal: Curr Opin Cell Biol
Title: Intercellular junctions and cellular polarity: the PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity.
Volume: 13
Issue: 5
Pages: 641-8
Publication
First Author: Monick MM
Year: 2000
Journal: J Immunol
Title: Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages.
Volume: 165
Issue: 8
Pages: 4632-9
Publication
First Author: Wodarz A
Year: 2000
Journal: J Cell Biol
Title: Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts.
Volume: 150
Issue: 6
Pages: 1361-74
Publication
First Author: Wu SL
Year: 1998
Journal: J Biol Chem
Title: Structure, expression, and properties of an atypical protein kinase C (PKC3) from Caenorhabditis elegans. PKC3 is required for the normal progression of embryogenesis and viability of the organism.
Volume: 273
Issue: 2
Pages: 1130-43
Protein Domain
Type: Family
Description: This group represents protein kinase C (KPC), including zeta/iota types from mammals, protein kinase C-like 3 from round worms []and atypical protein kinase C (aPKC) from fruit flies []. Protein kinase C iota type (PRKCI) is a calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway [, , ]. It is an indirect co-regulator of the stress-activated transcription factor HSF1 and the heat shock response []. It has been linked to cancers [, ].Protein kinase C zeta type is a calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory response and maintenance of long-term potentiation (LTP) [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 733  
Fragment?: false
Publication
First Author: Xu D
Year: 2008
Journal: EMBO Rep
Title: A transcription cofactor required for the heat-shock response.
Volume: 9
Issue: 7
Pages: 662-9
Publication
First Author: Lee JH
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Heat shock protein 90 (HSP90) inhibitors activate the heat shock factor 1 (HSF1) stress response pathway and improve glucose regulation in diabetic mice.
Volume: 430
Issue: 3
Pages: 1109-13
Publication
First Author: Elsing AN
Year: 2014
Journal: J Cell Biol
Title: Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival.
Volume: 206
Issue: 6
Pages: 735-49
Publication
First Author: Maheshwari M
Year: 2014
Journal: Hum Mol Genet
Title: Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of Huntington's disease.
Volume: 23
Issue: 10
Pages: 2737-51
Publication
First Author: McMillan DR
Year: 2002
Journal: Mol Cell Biol
Title: Heat shock transcription factor 2 is not essential for embryonic development, fertility, or adult cognitive and psychomotor function in mice.
Volume: 22
Issue: 22
Pages: 8005-14
Publication
First Author: Cui D
Year: 2023
Journal: Nat Commun
Title: Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy.
Volume: 14
Issue: 1
Pages: 7032
Publication
First Author: Sebag SC
Year: 2021
Journal: Cell Rep
Title: ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue.
Volume: 37
Issue: 7
Pages: 110003
Publication
First Author: Ling X
Year: 2022
Journal: iScience
Title: Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.
Volume: 25
Issue: 11
Pages: 105363
Publication  
First Author: Michel D
Year: 1997
Journal: Biochem J
Title: Stress-induced transcription of the clusterin/apoJ gene.
Volume: 328 ( Pt 1)
Pages: 45-50
Publication
First Author: Donmez G
Year: 2012
Journal: J Neurosci
Title: SIRT1 protects against α-synuclein aggregation by activating molecular chaperones.
Volume: 32
Issue: 1
Pages: 124-32
Publication
First Author: Mahat DB
Year: 2016
Journal: Mol Cell
Title: Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation.
Volume: 62
Issue: 1
Pages: 63-78
Publication    
First Author: Das S
Year: 2020
Journal: Elife
Title: Serotonin signaling by maternal neurons upon stress ensures progeny survival.
Volume: 9
Publication
First Author: Grunberg N
Year: 2021
Journal: Cancer Res
Title: Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles.
Volume: 81
Issue: 7
Pages: 1639-1653
Publication
First Author: Li G
Year: 2021
Journal: Nat Cell Biol
Title: LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy.
Volume: 23
Issue: 5
Pages: 526-537
Publication
First Author: Collins CB
Year: 2013
Journal: Mucosal Immunol
Title: Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function.
Volume: 6
Issue: 5
Pages: 960-71
Publication
First Author: Rokavec M
Year: 2012
Journal: Mol Cell
Title: IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis.
Volume: 45
Issue: 6
Pages: 777-89
Publication
First Author: Fujimoto M
Year: 2010
Journal: Mol Biol Cell
Title: A novel mouse HSF3 has the potential to activate nonclassical heat-shock genes during heat shock.
Volume: 21
Issue: 1
Pages: 106-16
Publication
First Author: Eroglu B
Year: 2014
Journal: Dev Biol
Title: An essential role for heat shock transcription factor binding protein 1 (HSBP1) during early embryonic development.
Volume: 386
Issue: 2
Pages: 448-60
Publication
First Author: Chen Z
Year: 2017
Journal: Diabetes
Title: Hepatic Activation of the FAM3C-HSF1-CaM Pathway Attenuates Hyperglycemia of Obese Diabetic Mice.
Volume: 66
Issue: 5
Pages: 1185-1197
Publication
First Author: Zhao R
Year: 2014
Journal: J Leukoc Biol
Title: Involvement of fibrinolytic regulators in adhesion of monocytes to vascular endothelial cells induced by glycated LDL and to aorta from diabetic mice.
Volume: 95
Issue: 6
Pages: 941-9
Publication
First Author: Ngalame NN
Year: 2013
Journal: Toxicol Sci
Title: Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure.
Volume: 131
Issue: 1
Pages: 225-33
Publication  
First Author: Rossin F
Year: 2018
Journal: EMBO Rep
Title: TG2 regulates the heat-shock response by the post-translational modification of HSF1.
Volume: 19
Issue: 7
Publication
First Author: Han D
Year: 2024
Journal: Acta Pharm Sin B
Title: Reprogramming tumor-associated macrophages and inhibiting tumor neovascularization by targeting MANF-HSF1-HSP70-1 pathway: An effective treatment for hepatocellular carcinoma.
Volume: 14
Issue: 10
Pages: 4396-4412
Publication
First Author: Das S
Year: 2016
Journal: Exp Cell Res
Title: Huntingtin interacting protein HYPK is a negative regulator of heat shock response and is downregulated in models of Huntington's Disease.
Volume: 343
Issue: 2
Pages: 107-117
Publication
First Author: Wang G
Year: 2003
Journal: Genesis
Title: Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis.
Volume: 36
Issue: 1
Pages: 48-61
Publication
First Author: Minsky N
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Direct link between metabolic regulation and the heat-shock response through the transcriptional regulator PGC-1α.
Volume: 112
Issue: 42
Pages: E5669-78
Publication
First Author: Newman B
Year: 2012
Journal: Cancer Res
Title: HSP90 inhibitor 17-AAG selectively eradicates lymphoma stem cells.
Volume: 72
Issue: 17
Pages: 4551-61
Publication
First Author: Boast B
Year: 2021
Journal: J Immunol
Title: A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice.
Volume: 206
Issue: 7
Pages: 1505-1514
Publication
First Author: Fiorenza MT
Year: 1995
Journal: Nucleic Acids Res
Title: Complex expression of murine heat shock transcription factors.
Volume: 23
Issue: 3
Pages: 467-74
Publication
First Author: Christians E
Year: 1997
Journal: Mol Cell Biol
Title: Evidence for the involvement of mouse heat shock factor 1 in the atypical expression of the HSP70.1 heat shock gene during mouse zygotic genome activation.
Volume: 17
Issue: 2
Pages: 778-88
Publication
First Author: Bevilacqua A
Year: 1997
Journal: Nucleic Acids Res
Title: Developmental activation of an episomic hsp70 gene promoter in two-cell mouse embryos by transcription factor Sp1.
Volume: 25
Issue: 7
Pages: 1333-8
Publication
First Author: Pierce A
Year: 2010
Journal: Biochem Biophys Res Commun
Title: A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice.
Volume: 402
Issue: 1
Pages: 59-65
Publication
First Author: Rozenfeld J
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: The pendrin anion exchanger gene is transcriptionally regulated by uroguanylin: a novel enterorenal link.
Volume: 302
Issue: 5
Pages: F614-24
Publication
First Author: Vihervaara A
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells.
Volume: 110
Issue: 36
Pages: E3388-97
Publication
First Author: Wang HY
Year: 2013
Journal: Mol Cell Biol
Title: Hyperthermia stress activates heat shock protein expression via propyl isomerase 1 regulation with heat shock factor 1.
Volume: 33
Issue: 24
Pages: 4889-99