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Search results 401 to 500 out of 530 for Irf1

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Type Details Score
Publication
20422028 | J:160136
First Author: Dietrich N
Year: 2010
Journal: PLoS One
Title: Murine toll-like receptor 2 activation induces type I interferon responses from endolysosomal compartments.
Volume: 5
Issue: 4
Pages: e10250
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Publication
27693356 | J:236523
First Author: Man SM
Year: 2016
Journal: Cell
Title: IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.
Volume: 167
Issue: 2
Pages: 382-396.e17
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Publication
1358285 | J:3017
First Author: Buckwalter MS
Year: 1992
Journal: Mamm Genome
Title: Localization of the human chromosome 5q genes Gabra-1, Gabrg-2, Il-4, Il-5, and Irf-1 on mouse chromosome 11.
Volume: 3
Issue: 10
Pages: 604-7
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Publication
23154982 | J:191206
First Author: Okamura D
Year: 2012
Journal: Genes Dev
Title: Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells.
Volume: 26
Issue: 22
Pages: 2477-82
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Publication
15800576 | J:97662
First Author: Honda K
Year: 2005
Journal: Nature
Title: IRF-7 is the master regulator of type-I interferon-dependent immune responses.
Volume: 434
Issue: 7034
Pages: 772-7
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Publication
23467089 | J:241283
First Author: Yosef N
Year: 2013
Journal: Nature
Title: Dynamic regulatory network controlling TH17 cell differentiation.
Volume: 496
Issue: 7446
Pages: 461-8
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Publication
9754575 | J:49877
First Author: Oliveira-dos-Santos AJ
Year: 1998
Journal: Eur J Immunol
Title: Thymic heterotypic cellular complexes in gene-targeted mice with defined blocks in T cell development and adhesion molecule expression.
Volume: 28
Issue: 9
Pages: 2882-92
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Publication
23444404 | J:197572
First Author: Rosborough BR
Year: 2013
Journal: Blood
Title: Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction.
Volume: 121
Issue: 18
Pages: 3619-30
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Publication
28894449 | J:354111
 
First Author: Auger JP
Year: 2017
Journal: Front Immunol
Title: Type I Interferon Induced by Streptococcus suis Serotype 2 is Strain-Dependent and May Be Beneficial for Host Survival.
Volume: 8
Pages: 1039
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Publication
32123346 | J:360216
First Author: Burke TP
Year: 2020
Journal: Nat Microbiol
Title: Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis.
Volume: 5
Issue: 5
Pages: 688-696
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Publication
21480215 | J:177313
First Author: Biondo C
Year: 2011
Journal: Eur J Immunol
Title: Recognition of yeast nucleic acids triggers a host-protective type I interferon response.
Volume: 41
Issue: 7
Pages: 1969-79
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Publication
23903655 | J:205017
First Author: Dorner M
Year: 2013
Journal: Nature
Title: Completion of the entire hepatitis C virus life cycle in genetically humanized mice.
Volume: 501
Issue: 7466
Pages: 237-41
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Publication
28468974 | J:247750
First Author: Zhu Q
Year: 2017
Journal: J Immunol
Title: Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1β.
Volume: 198
Issue: 11
Pages: 4210-4215
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Publication
19652017 | J:152182
First Author: McWhirter SM
Year: 2009
Journal: J Exp Med
Title: A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP.
Volume: 206
Issue: 9
Pages: 1899-911
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Publication
20637660 | J:162548
First Author: Farlik M
Year: 2010
Journal: Immunity
Title: Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression.
Volume: 33
Issue: 1
Pages: 25-34
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Publication
10655497 | J:60187
First Author: Zhu Y
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Genomic interval engineering of mice identifies a novel modulator of triglyceride production.
Volume: 97
Issue: 3
Pages: 1137-42
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Publication
21903422 | J:176666
First Author: Li S
Year: 2011
Journal: Immunity
Title: Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.
Volume: 35
Issue: 3
Pages: 426-40
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19201871 | J:144791
First Author: Bode KA
Year: 2009
Journal: J Immunol
Title: Kinetic of RelA activation controls magnitude of TLR-mediated IL-12p40 induction.
Volume: 182
Issue: 4
Pages: 2176-84
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Publication
27022145 | J:233072
First Author: Masuda K
Year: 2016
Journal: J Exp Med
Title: Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA.
Volume: 213
Issue: 4
Pages: 605-19
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10704283 | J:60872
First Author: Wenderfer SE
Year: 2000
Journal: Genomics
Title: Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11.
Volume: 63
Issue: 3
Pages: 354-73
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Publication
27211851 | J:239920
 
First Author: Kobayashi EH
Year: 2016
Journal: Nat Commun
Title: Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.
Volume: 7
Pages: 11624
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Publication
30131424 | J:267220
 
First Author: Tomasello E
Year: 2018
Journal: EMBO J
Title: Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection.
Volume: 37
Issue: 19
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Publication
32150572 | J:287406
First Author: Place DE
Year: 2020
Journal: PLoS Pathog
Title: Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.
Volume: 16
Issue: 3
Pages: e1008364
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Publication
30510167 | J:287363
First Author: Briard B
Year: 2019
Journal: Nat Microbiol
Title: Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection.
Volume: 4
Issue: 2
Pages: 316-327
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Publication
21820332 | J:175845
First Author: Sharma S
Year: 2011
Journal: Immunity
Title: Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Volume: 35
Issue: 2
Pages: 194-207
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Publication
9177770 | J:40728
First Author: Krulová M
Year: 1997
Journal: Genomics
Title: IL-2-induced proliferative response is controlled by loci Cinda1 and Cinda2 on mouse chromosomes 11 and 12: a distinct control of the response induced by different IL-2 concentrations.
Volume: 42
Issue: 1
Pages: 11-5
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Publication
20599664 | J:177242
First Author: Kojic S
Year: 2010
Journal: Arch Biochem Biophys
Title: A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein.
Volume: 502
Issue: 1
Pages: 60-7
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Publication
33238123 | J:300359
First Author: Zhang H
Year: 2020
Journal: Cell Rep
Title: An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets.
Volume: 33
Issue: 8
Pages: 108433
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Publication
29576451 | J:262477
First Author: Karki R
Year: 2018
Journal: Cell
Title: IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Volume: 173
Issue: 4
Pages: 920-933.e13
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Publication
33278357 | J:361144
First Author: Karki R
Year: 2021
Journal: Cell
Title: Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Volume: 184
Issue: 1
Pages: 149-168.e17
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Publication
32245826 | J:292181
First Author: van der Weyden L
Year: 2020
Journal: G3 (Bethesda)
Title: A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation.
Volume: 10
Issue: 6
Pages: 1869-1877
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Publication
32428860 | J:336999
First Author: Riedelberger M
Year: 2020
Journal: iScience
Title: Type I Interferons Ameliorate Zinc Intoxication of Candida glabrata by Macrophages and Promote Fungal Immune Evasion.
Volume: 23
Issue: 5
Pages: 101121
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Publication
22366192 | J:184926
First Author: Blackburn J
Year: 2012
Journal: Dev Biol
Title: The role of Irf6 in tooth epithelial invagination.
Volume: 365
Issue: 1
Pages: 61-70
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Publication
32553121 | J:296045
First Author: Patmore DM
Year: 2020
Journal: Dev Cell
Title: DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma.
Volume: 54
Issue: 4
Pages: 455-470.e5
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Publication
32075740 | J:349194
First Author: Riedelberger M
Year: 2020
Journal: Cell Host Microbe
Title: Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection.
Volume: 27
Issue: 3
Pages: 454-466.e8
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Publication
8595891 | J:29693
First Author: Spicer AP
Year: 1995
Journal: Genomics
Title: The human and mouse receptors for hyaluronan-mediated motility, RHAMM, genes (HMMR) map to human chromosome 5q33.2-qter and mouse chromosome 11.
Volume: 30
Issue: 1
Pages: 115-7
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Publication
9070927 | J:37827
First Author: Watkins-Chow DE
Year: 1997
Journal: Genomics
Title: Genetic mapping of 21 genes on mouse chromosome 11 reveals disruptions in linkage conservation with human chromosome 5.
Volume: 40
Issue: 1
Pages: 114-22
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Publication
29950673 | J:266104
First Author: Choi JH
Year: 2018
Journal: Nat Commun
Title: mTORC1 accelerates retinal development via the immunoproteasome.
Volume: 9
Issue: 1
Pages: 2502
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Publication
35315772 | J:322321
   
First Author: Catela C
Year: 2022
Journal: Elife
Title: Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity.
Volume: 11
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Publication
35493520 | J:324243
 
First Author: Lei Z
Year: 2022
Journal: Front Immunol
Title: EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice.
Volume: 13
Pages: 843378
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
25463511 | -
First Author: Gu M
Year: 2015
Journal: Dev Comp Immunol
Title: Ctenopharyngodon idella IRF2 plays an antagonistic role to IRF1 in transcriptional regulation of IFN and ISG genes.
Volume: 49
Issue: 1
Pages: 103-12
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Interaction Experiment
Ramsauer K (2007)
Description: Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.
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Allele
Irf1<em2Smoc> | MGI:7290569
Name: interferon regulatory factor 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Irf1<em1Smoc> | MGI:7290568
Name: interferon regulatory factor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6354945 | C57BL/6JSmoc-Irf1<em2Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Irf1<m2Btlr> | MGI:6269374
Name: interferon regulatory factor 1; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Irf1<M3Btlr> | MGI:6269378
Name: interferon regulatory factor 1; mutation 3, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:7623406 | C57BL/6JSmoc-Irf1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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HT Experiment
E-GEOD-11809 | Transcription profiling of mouse wild type, IFNg-/- and IRF1-/- animals infected with from M. avium
Series Id: GSE11809
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein Domain
IPR031218 | IRF2
Type: Family
Description: Interferon regulatory factor 2 (IRF2) is a multifunctional transcription factor that plays a pivotal role in regulation of apoptosis and cell cycle control [, , ]. It also plays an important role in modulating cellular responses to interferon (IFN) and viral infection []. It has an antagonistic role to IRF1 in transcriptional regulation of IFN and ISG genes []. While IRF1 acts as a positive regulator, IRF2 is known to repress IFN-mediated gene expression.
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Strain
MGI:6269375 | C57BL/6J-Irf1<m2Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Strain
MGI:6269379 | C57BL/6J-Irf1<M3Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Genotype
Genotype
Symbol: Irf1/Irf1
Background: C57BL/6J-Irf1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Irf1/Irf1
Background: C57BL/6J-Irf1
Zygosity: hm
Has Mutant Allele: true
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Publication
25755403 | -
First Author: Mukherjee RM
Year: 2012
Journal: J Clin Exp Hepatol
Title: Human Interferon Regulatory Factor 2 Gene Expression is Induced in Chronic Hepatitis C Virus Infection-A Possible Mode of Viral Persistence.
Volume: 2
Issue: 1
Pages: 27-34
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Publication
8438157 | -
First Author: Harada H
Year: 1993
Journal: Science
Title: Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2.
Volume: 259
Issue: 5097
Pages: 971-4
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Publication
12738767 | -
First Author: Masumi A
Year: 2003
Journal: J Biol Chem
Title: Interferon regulatory factor-2 regulates cell growth through its acetylation.
Volume: 278
Issue: 28
Pages: 25401-7
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Publication
8713742 | -
First Author: Taniguchi T
Year: 1995
Journal: Indian J Biochem Biophys
Title: IRF-1 and IRF-2 as regulators of the interferon system and cell growth.
Volume: 32
Issue: 5
Pages: 235-9
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Protein Domain
IPR017431 | IRF1/IRF2
Type: Family
Description: This entry represents the interferon regulatory factor 1/2.IRF1 is a transcriptional regulator involved in the regulation of several cellular responses, such as regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage [, , , , , ].IRF2 is a multifunctional transcription factor that plays a pivotal role in regulation of apoptosis and cell cycle control [, , ]. It also plays an important role in modulating cellular responses to interferon (IFN) and viral infection []. It has an antagonistic role to IRF1 in transcriptional regulation of IFN and ISG genes []. While IRF1 acts as a positive regulator, IRF2 is known to repress IFN-mediated gene expression.
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