|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 401 to 500 out of 572 for Irf7

<< First    < Previous  |  Next >    Last >>
0.026s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
29576451 | J:262477
First Author: Karki R
Year: 2018
Journal: Cell
Title: IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Volume: 173
Issue: 4
Pages: 920-933.e13
•
•
•
•
•
Publication
33278357 | J:361144
First Author: Karki R
Year: 2021
Journal: Cell
Title: Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Volume: 184
Issue: 1
Pages: 149-168.e17
•
•
•
•
•
Publication
32245826 | J:292181
First Author: van der Weyden L
Year: 2020
Journal: G3 (Bethesda)
Title: A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation.
Volume: 10
Issue: 6
Pages: 1869-1877
•
•
•
•
•
Publication
22366192 | J:184926
First Author: Blackburn J
Year: 2012
Journal: Dev Biol
Title: The role of Irf6 in tooth epithelial invagination.
Volume: 365
Issue: 1
Pages: 61-70
•
•
•
•
•
Publication
28400473 | J:242009
First Author: Choo MK
Year: 2017
Journal: J Exp Med
Title: TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.
Volume: 214
Issue: 5
Pages: 1297-1311
•
•
•
•
•
Publication
25681338 | J:274041
First Author: Onishi M
Year: 2015
Journal: J Immunol
Title: Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Volume: 194
Issue: 6
Pages: 2673-82
•
•
•
•
•
Publication
38395995 | J:345820
First Author: Cardarelli S
Year: 2024
Journal: Cell Death Dis
Title: Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress.
Volume: 15
Issue: 2
Pages: 169
•
•
•
•
•
Publication
30733279 | J:272586
 
First Author: Suzuki T
Year: 2019
Journal: Development
Title: Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.
Volume: 146
Issue: 4
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
•
•
•
•
•
Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
•
•
•
•
•
Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
•
•
•
•
•
Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
•
•
•
•
•
Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
•
•
•
•
•
Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
34506605 | J:317342
First Author: Zhao M
Year: 2021
Journal: PLoS Pathog
Title: Myeloid neddylation targets IRF7 and promotes host innate immunity against RNA viruses.
Volume: 17
Issue: 9
Pages: e1009901
•
•
•
•
•
Publication
25911105 | J:222561
First Author: Zhou Q
Year: 2015
Journal: J Biol Chem
Title: Aryl Hydrocarbon Receptor Interacting Protein Targets IRF7 to Suppress Antiviral Signaling and the Induction of Type I Interferon.
Volume: 290
Issue: 23
Pages: 14729-39
•
•
•
•
•
Pathway
R-MMU-933541 | TRAF6 mediated IRF7 activation
•
•
•
•
•
Publication
21167755 | J:167719
First Author: Yu Y
Year: 2010
Journal: Immunity
Title: The ubiquitin E3 ligase RAUL negatively regulates type i interferon through ubiquitination of the transcription factors IRF7 and IRF3.
Volume: 33
Issue: 6
Pages: 863-77
•
•
•
•
•
Allele
Irf7<em1Smoc> | MGI:7290581
Name: interferon regulatory factor 7; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Strain
MGI:6429003 | C57BL/6JSmoc-Irf7<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Interaction Experiment
Siednienko J (2012)
Description: Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons.
•
•
•
•
•
Pathway
R-MMU-936964 | Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)
•
•
•
•
•
Pathway
R-MMU-9824878 | Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7
•
•
•
•
•
Pathway
R-MMU-975110 | TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
•
•
•
•
•
DO Term
DOID:0111969 | immunodeficiency 39
•
•
•
•
•
Publication
11124948 | -
First Author: Smith EJ
Year: 2001
Journal: J Biol Chem
Title: IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein.
Volume: 276
Issue: 12
Pages: 8951-7
•
•
•
•
•
Protein Coding Gene
MGI:107676 | Tank
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
P70347
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: false
•
•
•
•
•
Ontology Term
- | Inhibition of host IKBKE by virus
•
•
•
•
•
Ontology Term
- | Inhibition of host TBK1 by virus
•
•
•
•
•
Protein Coding Gene
MGI:2136419 | Sarm1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q6PDS3
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
•
•
•
•
•
Ontology Term
- | Inhibition of host RLR pathway by virus
•
•
•
•
•
Ontology Term
- | Inhibition of host TLR pathway by virus
•
•
•
•
•
Publication
8668343 | -
First Author: Bao J
Year: 1996
Journal: Oncogene
Title: Isolation and characterization of Nmi, a novel partner of Myc proteins.
Volume: 12
Issue: 10
Pages: 2171-6
•
•
•
•
•
Publication
11916966 | -
First Author: Li H
Year: 2002
Journal: J Biol Chem
Title: A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer.
Volume: 277
Issue: 23
Pages: 20965-73
•
•
•
•
•
Publication
17406968 | -
First Author: Zhang K
Year: 2007
Journal: Mol Cell Biochem
Title: Stability of Nmi protein is controlled by its association with Tip60.
Volume: 303
Issue: 1-2
Pages: 1-8
•
•
•
•
•
Publication
23034180 | -
First Author: Li Z
Year: 2012
Journal: Mol Biol Cell
Title: NMI mediates transcription-independent ARF regulation in response to cellular stresses.
Volume: 23
Issue: 23
Pages: 4635-46
•
•
•
•
•
Publication
9989503 | -
First Author: Zhu M
Year: 1999
Journal: Cell
Title: Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling.
Volume: 96
Issue: 1
Pages: 121-30
•
•
•
•
•
Publication
27012186 | -
First Author: Hou J
Year: 2016
Journal: Cancer Lett
Title: N-Myc-interacting protein (NMI) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-κB/p65.
Volume: 376
Issue: 1
Pages: 22-33
•
•
•
•
•
Publication
9781816 | -
First Author: Lebrun SJ
Year: 1998
Journal: J Interferon Cytokine Res
Title: Interferon-induced upregulation and cytoplasmic localization of Myc-interacting protein Nmi.
Volume: 18
Issue: 9
Pages: 767-71
•
•
•
•
•
Publication
19358268 | -
First Author: Fillmore RA
Year: 2009
Journal: Int J Cancer
Title: Nmi (N-Myc interactor) inhibits Wnt/beta-catenin signaling and retards tumor growth.
Volume: 125
Issue: 3
Pages: 556-64
•
•
•
•
•
Protein Domain
IPR033527 | NMI
Type: Family
Description: Originally identified as an N-Myc-interacting protein, NMI is an interferon-gamma inducible transcription cofactor that is responsible for enhancing IFN-gamma-dependent transcription [, ]. NMI interacts with a variety of transcription factors, including c-Myc, TIP60, some STAT family members, BRCA1, ARF and IRF7 [, , , , , ]. NMI participates in cell cycle control, DNA damage responses and tumorigenesis. It can suppress tumour growth and metastasis by inhibiting NF-kB pathways []and Wnt/beta-catenin signalling [].
•
•
•
•
•
Protein Coding Gene
MGI:108041 | Traf3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q60803
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: false
•
•
•
•
•
Protein Coding Gene
MGI:1929612 | Ikbke
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1929658 | Tbk1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1918898 | Optn
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q9R0T8
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
•
•
•
•
•
Protein
P70434
Organism: Mus musculus/domesticus
Length: 457  
Fragment?: false
•
•
•
•
•
Protein
Q8K3K8
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: false
•
•
•
•
•
Protein
Q9WUN2
Organism: Mus musculus/domesticus
Length: 729  
Fragment?: false
•
•
•
•
•
Protein
B7ZD12
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
•
•
•
•
•
Publication
10950963 | -
First Author: Chen J
Year: 2000
Journal: J Biol Chem
Title: Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35.
Volume: 275
Issue: 46
Pages: 36278-84
•
•
•
•
•
Publication
17468758 | J:122421
First Author: Zhao T
Year: 2007
Journal: Nat Immunol
Title: The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways.
Volume: 8
Issue: 6
Pages: 592-600
•
•
•
•
•
Protein Coding Gene
MGI:1341909 | Ly96
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:2147032 | Ticam1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:88318 | Cd14
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:3040056 | Ticam2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:96824 | Tlr4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1859179 | Irf3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q9JHF9
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: false
•
•
•
•
•
Protein
P10810
Organism: Mus musculus/domesticus
Length: 366  
Fragment?: false
•
•
•
•
•
Protein
P70671
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
•
•
•
•
•
Protein
Q80UF7
Organism: Mus musculus/domesticus
Length: 732  
Fragment?: false
•
•
•
•
•
Protein
Q9QUK6
Organism: Mus musculus/domesticus
Length: 835  
Fragment?: false
•
•
•
•
•
Protein
Q8BJQ4
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom