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Search results 401 to 488 out of 488 for Irs1

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Type Details Score
Publication
12107166 | -
First Author: Bowden ET
Year: 2002
Journal: J Biol Chem
Title: Anti-apoptotic signaling of pleiotrophin through its receptor, anaplastic lymphoma kinase.
Volume: 277
Issue: 39
Pages: 35862-8
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Publication
11278720 | -
First Author: Stoica GE
Year: 2001
Journal: J Biol Chem
Title: Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin.
Volume: 276
Issue: 20
Pages: 16772-9
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Publication
12122009 | -
First Author: Stoica GE
Year: 2002
Journal: J Biol Chem
Title: Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types.
Volume: 277
Issue: 39
Pages: 35990-8
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Protein Domain
IPR026830 | ALK
Type: Family
Description: ALK tyrosine kinase receptor (also known as anaplastic lymphoma kinase, ALK) is a neuronal orphan receptor tyrosine kinase that is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an important role in the genesis and differentiation of the nervous system [].ALK transduces signals from ligands at the cell surface, through specific activation of the mitogen-activated protein kinase (MAPK) pathway. Following activation by ligand, ALK induces tyrosine phosphorylation of CBL, FRS2, IRS1 and SHC1, as well as of the MAP kinases MAPK1/ERK2 and MAPK3/ERK1 [, , ]. ALK acts as a receptor for ligands pleiotrophin (PTN), a secreted growth factor, and midkine (MDK), a PTN-related factor, thus participating in PTN and MDK signal transduction. PTN-binding induces MAPK pathway activation, which is important for the anti-apoptotic signaling of PTN and regulation of cell proliferation [, ]. MDK-binding induces phosphorylation of the ALK target insulin receptor substrate (IRS1), activates mitogen-activated protein kinases (MAPKs) and PI3-kinase, resulting also in cell proliferation induction [].
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Publication
17565041 | J:124086
First Author: Li Z
Year: 2007
Journal: Mol Endocrinol
Title: SH2B1 enhances leptin signaling by both Janus kinase 2 Tyr813 phosphorylation-dependent and -independent mechanisms.
Volume: 21
Issue: 9
Pages: 2270-81
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Publication
29106399 | J:252611
First Author: Awazawa M
Year: 2017
Journal: Nat Med
Title: A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle.
Volume: 23
Issue: 12
Pages: 1466-1473
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Publication
26720454 | J:231029
First Author: Arroba AI
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Inhibition of Protein Tyrosine Phosphatase 1B Improves IGF-I Receptor Signaling and Protects Against Inflammation-Induced Gliosis in the Retina.
Volume: 56
Issue: 13
Pages: 8031-44
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Publication
15181014 | J:121205
First Author: Shi H
Year: 2004
Journal: J Biol Chem
Title: Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling.
Volume: 279
Issue: 33
Pages: 34733-40
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Publication
22326951 | J:184484
First Author: Battiprolu PK
Year: 2012
Journal: J Clin Invest
Title: Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice.
Volume: 122
Issue: 3
Pages: 1109-18
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Publication
20197085 | J:164141
First Author: Swindell WR
Year: 2010
Journal: Exp Gerontol
Title: In vivo analysis of gene expression in long-lived mice lacking the pregnancy-associated plasma protein A (PappA) gene.
Volume: 45
Issue: 5
Pages: 366-74
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Publication
20967535 | J:166051
First Author: Kuo LH
Year: 2011
Journal: Diabetologia
Title: Toll-like receptor 2 deficiency improves insulin sensitivity and hepatic insulin signalling in the mouse.
Volume: 54
Issue: 1
Pages: 168-79
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Publication
15306821 | J:92663
First Author: Um SH
Year: 2004
Journal: Nature
Title: Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.
Volume: 431
Issue: 7005
Pages: 200-5
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Publication
12101187 | J:79280
First Author: Kido Y
Year: 2002
Journal: J Biol Chem
Title: Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance.
Volume: 277
Issue: 39
Pages: 36740-7
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Publication
10995442 | J:68751
First Author: Sachs M
Year: 2000
Journal: J Cell Biol
Title: Essential role of Gab1 for signaling by the c-Met receptor in vivo.
Volume: 150
Issue: 6
Pages: 1375-84
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Publication
32101031 | J:296811
First Author: Zhang L
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40.
Volume: 318
Issue: 5
Pages: E625-E635
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Publication
24397921 | J:211950
First Author: Poursharifi P
Year: 2014
Journal: Mol Cell Endocrinol
Title: C5aR and C5L2 act in concert to balance immunometabolism in adipose tissue.
Volume: 382
Issue: 1
Pages: 325-33
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Publication
30031227 | J:348501
First Author: Tramutola A
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease.
Volume: 1864
Issue: 10
Pages: 3309-3321
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Publication
24435134 | J:210098
 
First Author: Ong QR
Year: 2014
Journal: Sci Rep
Title: Reduced phosphorylation of brain insulin receptor substrate and Akt proteins in apolipoprotein-E4 targeted replacement mice.
Volume: 4
Pages: 3754
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Publication
20841350 | J:167406
First Author: Matsuo K
Year: 2010
Journal: J Biol Chem
Title: Altered glucose homeostasis in mice with liver-specific deletion of Src homology phosphatase 2.
Volume: 285
Issue: 51
Pages: 39750-8
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Publication
20407209 | J:161466
First Author: Shimizu I
Year: 2010
Journal: J Clin Invest
Title: Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents.
Volume: 120
Issue: 5
Pages: 1506-14
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Publication
22418434 | J:185463
First Author: Inazuka F
Year: 2012
Journal: J Biol Chem
Title: Muscle-specific knock-out of NUAK family SNF1-like kinase 1 (NUAK1) prevents high fat diet-induced glucose intolerance.
Volume: 287
Issue: 20
Pages: 16379-89
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Publication
29795582 | J:262390
First Author: Taga M
Year: 2018
Journal: PLoS One
Title: PKR modulates abnormal brain signaling in experimental obesity.
Volume: 13
Issue: 5
Pages: e0196983
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Publication
24379345 | J:229139
First Author: Wu S
Year: 2014
Journal: Diabetes
Title: Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell.
Volume: 63
Issue: 4
Pages: 1270-82
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Publication
22076926 | J:191388
First Author: Wu S
Year: 2012
Journal: Diabetes
Title: Reproductive tissues maintain insulin sensitivity in diet-induced obesity.
Volume: 61
Issue: 1
Pages: 114-23
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Publication
23396401 | J:208551
First Author: Zhang W
Year: 2013
Journal: Diabetes
Title: Liver kinase b1 is required for white adipose tissue growth and differentiation.
Volume: 62
Issue: 7
Pages: 2347-58
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Publication
31336149 | J:280511
First Author: Hörbelt T
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver.
Volume: 1865
Issue: 10
Pages: 2671-2684
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Publication
15314154 | J:92794
First Author: Duan C
Year: 2004
Journal: Mol Cell Biol
Title: Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance.
Volume: 24
Issue: 17
Pages: 7435-43
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Publication
33297755 | J:318576
First Author: Sun J
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial TFEB (Transcription Factor EB) Improves Glucose Tolerance via Upregulation of IRS (Insulin Receptor Substrate) 1 and IRS2.
Volume: 41
Issue: 2
Pages: 783-795
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Publication
19723629 | J:155840
First Author: Kienesberger PC
Year: 2009
Journal: J Biol Chem
Title: Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling.
Volume: 284
Issue: 44
Pages: 30218-29
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Publication
26801556 | J:233337
First Author: Jeong HW
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Tribbles 3 inhibits brown adipocyte differentiation and function by suppressing insulin signaling.
Volume: 470
Issue: 4
Pages: 783-91
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Publication
29386390 | J:258290
First Author: Wardhana DA
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Family with sequence similarity 13, member A modulates adipocyte insulin signaling and preserves systemic metabolic homeostasis.
Volume: 115
Issue: 7
Pages: 1529-1534
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Publication
24265765 | J:338241
First Author: Myers SA
Year: 2013
Journal: PLoS One
Title: The zinc transporter, Slc39a7 (Zip7) is implicated in glycaemic control in skeletal muscle cells.
Volume: 8
Issue: 11
Pages: e79316
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Publication
15572028 | J:161023
First Author: Mohanty S
Year: 2005
Journal: Exp Cell Res
Title: Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis.
Volume: 303
Issue: 1
Pages: 68-78
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Publication
10422536 | J:159275
First Author: Cui X
Year: 1999
Journal: Mutat Res
Title: The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells.
Volume: 434
Issue: 2
Pages: 75-88
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Publication
15699039 | J:98748
First Author: Wharton J
Year: 2005
Journal: J Biol Chem
Title: Dissociation of insulin receptor expression and signaling from caveolin-1 expression.
Volume: 280
Issue: 14
Pages: 13483-6
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Publication
16505233 | J:106855
First Author: Shi H
Year: 2006
Journal: Diabetes
Title: Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance.
Volume: 55
Issue: 3
Pages: 699-707
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Publication
16916938 | J:115991
First Author: Guo S
Year: 2006
Journal: Mol Endocrinol
Title: The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.
Volume: 20
Issue: 12
Pages: 3389-99
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Publication
19675138 | J:154382
First Author: Morgan SA
Year: 2009
Journal: Diabetes
Title: 11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.
Volume: 58
Issue: 11
Pages: 2506-15
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Publication
21305007 | J:169542
First Author: Matsuo K
Year: 2011
Journal: PLoS One
Title: Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1B.
Volume: 6
Issue: 1
Pages: e16446
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Publication
23201159 | J:198859
First Author: Yin Y
Year: 2013
Journal: Biochim Biophys Acta
Title: Downregulation of miR-145 associated with cancer progression and VEGF transcriptional activation by targeting N-RAS and IRS1.
Volume: 1829
Issue: 2
Pages: 239-47
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Publication
28724990 | J:251732
First Author: Zillikens MC
Year: 2017
Journal: Nat Commun
Title: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Volume: 8
Issue: 1
Pages: 80
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Publication
28655716 | J:259731
First Author: Ohlsson C
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice.
Volume: 313
Issue: 4
Pages: E450-E462
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Publication
29440699 | J:263023
First Author: Nguyen Dinh Cat A
Year: 2018
Journal: Sci Rep
Title: Vascular dysfunction in obese diabetic db/db mice involves the interplay between aldosterone/mineralocorticoid receptor and Rho kinase signaling.
Volume: 8
Issue: 1
Pages: 2952
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Publication
30509997 | J:268948
First Author: Andersson KME
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis.
Volume: 115
Issue: 51
Pages: E12063-E12072
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Publication
29685905 | J:265277
 
First Author: Mercado-Matos J
Year: 2018
Journal: Mol Cell Biol
Title: Identification of a Novel Invasion-Promoting Region in Insulin Receptor Substrate 2.
Volume: 38
Issue: 14
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Publication
27200419 | J:283266
 
First Author: Park K
Year: 2016
Journal: JCI Insight
Title: Insulin decreases atherosclerosis by inducing endothelin receptor B expression.
Volume: 1
Issue: 6
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Publication
33408127 | J:306294
First Author: Liao W
Year: 2021
Journal: Diabetes
Title: Heme Oxygenase-1 Regulates Ferrous Iron and Foxo1 in Control of Hepatic Gluconeogenesis.
Volume: 70
Issue: 3
Pages: 696-709
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Publication
27765041 | J:316548
First Author: Farabaugh SM
Year: 2016
Journal: Cell Commun Signal
Title: Lack of interaction between ErbB2 and insulin receptor substrate signaling in breast cancer.
Volume: 14
Issue: 1
Pages: 25
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Publication
32531054 | J:356106
First Author: Nolte MJ
Year: 2020
Journal: Genome Biol Evol
Title: Giant Island Mice Exhibit Widespread Gene Expression Changes in Key Metabolic Organs.
Volume: 12
Issue: 8
Pages: 1277-1301
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Protein
Q8VHQ2
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
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Protein
A0A571BEJ5
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Publication
12138094 | -
First Author: Pandini G
Year: 2002
Journal: J Biol Chem
Title: Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.
Volume: 277
Issue: 42
Pages: 39684-95
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Publication
16831875 | -
First Author: Slaaby R
Year: 2006
Journal: J Biol Chem
Title: Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant.
Volume: 281
Issue: 36
Pages: 25869-74
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Publication
8276809 | -
First Author: Van Horn DJ
Year: 1994
Journal: J Biol Chem
Title: Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor.
Volume: 269
Issue: 1
Pages: 29-32
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Protein Domain
IPR016246 | Tyr_kinase_insulin-like_rcpt
Type: Family
Description: Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases. Protein kinases catalyse the transfer of the gamma phosphate from nucleotide triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. Phosphoprotein phosphatases catalyse the reverse process. Protein kinases fall into three broad classes, characterised with respect to substrate specificity []:Serine/threonine-protein kinasesTyrosine-protein kinasesDual specificity protein kinases (e.g. MEK - phosphorylates both Thr and Tyr on target proteins)Protein kinase function is evolutionarily conserved from Escherichia coli to human []. Protein kinases play a role in a multitude of cellular processes, including division, proliferation, apoptosis, and differentiation []. Phosphorylation usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins. The catalytic subunits of protein kinases are highly conserved, and several structures have been solved [], leading to large screens to develop kinase-specific inhibitors for the treatments of a number of diseases [].Tyrosine-protein kinases can transfer a phosphate group from ATP to a tyrosine residue in a protein. These enzymes can be divided into two main groups []:Receptor tyrosine kinases (RTK), which are transmembrane proteins involved in signal transduction; they play key roles in growth, differentiation, metabolism, adhesion, motility, death and oncogenesis []. RTKs are composed of 3 domains: an extracellular domain (binds ligand), a transmembrane (TM) domain, and an intracellular catalytic domain (phosphorylates substrate). The TM domain plays an important role in the dimerisation process necessary for signal transduction []. Cytoplasmic / non-receptor tyrosine kinases, which act as regulatory proteins, playing key roles in cell differentiation, motility, proliferation, and survival. For example, the Src-family of protein-tyrosine kinases [].This entry represents the insulin receptor, as well as related insulin-like receptors. The insulin receptor binds insulin and has a tyrosine-protein kinase activity, and mediates the metabolic functions of insulin. Binding to insulin stimulates the association of the receptor with downstream mediators, including IRS1 and phosphatidylinositol 3'-kinase (PI3K). The insulin receptor can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When the insulin receptor is present in a hybrid receptor with IGF1R (insulin growth factor receptor), it binds IGF1 (insulin growth factor 1) [, , ].
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Publication
14516276 | J:159073
First Author: Kimber WA
Year: 2003
Journal: Biochem J
Title: Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.
Volume: 376
Issue: Pt 2
Pages: 525-35
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Publication
23056509 | J:192101
First Author: Munkonda MN
Year: 2012
Journal: PLoS One
Title: Recombinant acylation stimulating protein administration to C3-/- mice increases insulin resistance via adipocyte inflammatory mechanisms.
Volume: 7
Issue: 10
Pages: e46883
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Publication
25361392 | J:218271
First Author: Alvarez-Perez JC
Year: 2014
Journal: Mol Endocrinol
Title: Hepatocyte growth factor ameliorates hyperglycemia and corrects β-cell mass in IRS2-deficient mice.
Volume: 28
Issue: 12
Pages: 2038-48
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Publication
20821187 | J:164577
First Author: Liu Y
Year: 2010
Journal: Diabetologia
Title: Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice.
Volume: 53
Issue: 12
Pages: 2600-10
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Publication
11113183 | J:67575
First Author: Dufresne SD
Year: 2001
Journal: Mol Cell Biol
Title: Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice.
Volume: 21
Issue: 1
Pages: 81-7
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Publication
25099774 | J:310290
First Author: Schneider A
Year: 2014
Journal: Age (Dordr)
Title: Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries.
Volume: 36
Issue: 4
Pages: 9701
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Publication
33516914 | J:322056
 
First Author: Lanzillotta C
Year: 2021
Journal: Free Radic Biol Med
Title: Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndrome.
Volume: 165
Pages: 152-170
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Publication
24887203 | J:217927
First Author: Pedrós I
Year: 2014
Journal: Biochim Biophys Acta
Title: Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease.
Volume: 1842
Issue: 9
Pages: 1556-66
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Publication
23056418 | J:192102
First Author: Al-Dwairi A
Year: 2012
Journal: PLoS One
Title: Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice.
Volume: 7
Issue: 10
Pages: e46716
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Publication
28870245 | J:310256
First Author: Consitt LA
Year: 2017
Journal: Skelet Muscle
Title: Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass.
Volume: 7
Issue: 1
Pages: 17
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Publication
23606743 | J:328153
First Author: Motohashi N
Year: 2013
Journal: J Cell Sci
Title: Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis.
Volume: 126
Issue: Pt 12
Pages: 2678-91
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Publication
30462534 | J:272012
First Author: Wang Y
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.
Volume: 316
Issue: 2
Pages: C223-C234
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Publication
33872860 | J:316885
 
First Author: Altamura S
Year: 2021
Journal: Mol Metab
Title: Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload.
Volume: 51
Pages: 101235
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Publication
9869640 | -
First Author: Kamura T
Year: 1998
Journal: Genes Dev
Title: The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families.
Volume: 12
Issue: 24
Pages: 3872-81
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Protein
Q8BJL1
Organism: Mus musculus/domesticus
Length: 746  
Fragment?: false
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Protein
P62932
Organism: Mus musculus/domesticus
Length: 710  
Fragment?: false
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Protein
Q5DTZ7
Organism: Mus musculus/domesticus
Length: 716  
Fragment?: true
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Protein
Q3KN92
Organism: Mus musculus/domesticus
Length: 710  
Fragment?: false
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Publication
16675548 | -
First Author: Bullock AN
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.
Volume: 103
Issue: 20
Pages: 7637-42
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Protein
Q9WTL4
Organism: Mus musculus/domesticus
Length: 1300  
Fragment?: false
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Protein
Q60751
Organism: Mus musculus/domesticus
Length: 1373  
Fragment?: false
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Protein
P15208
Organism: Mus musculus/domesticus
Length: 1372  
Fragment?: false
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Protein
P97793
Organism: Mus musculus/domesticus
Length: 1621  
Fragment?: false
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Protein
E9QNX9
Organism: Mus musculus/domesticus
Length: 1369  
Fragment?: false
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Protein
M4TKR7
Organism: Mus musculus/domesticus
Length: 1384  
Fragment?: false
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Publication
19275641 | -
First Author: Sharma PS
Year: 2009
Journal: Curr Pharm Des
Title: Receptor tyrosine kinase inhibitors as potent weapons in war against cancers.
Volume: 15
Issue: 7
Pages: 758-76
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Publication
16700535 | -
First Author: Li E
Year: 2006
Journal: Biochemistry
Title: Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.
Volume: 45
Issue: 20
Pages: 6241-51
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Publication
15845350 | -
First Author: Roskoski R Jr
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Src kinase regulation by phosphorylation and dephosphorylation.
Volume: 331
Issue: 1
Pages: 1-14
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Publication
3291115 | J:31015
First Author: Hanks SK
Year: 1988
Journal: Science
Title: The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
Volume: 241
Issue: 4861
Pages: 42-52
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Publication
12368087 | -
First Author: Manning G
Year: 2002
Journal: Trends Biochem Sci
Title: Evolution of protein kinase signaling from yeast to man.
Volume: 27
Issue: 10
Pages: 514-20
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Publication
12471243 | -
First Author: Manning G
Year: 2002
Journal: Science
Title: The protein kinase complement of the human genome.
Volume: 298
Issue: 5600
Pages: 1912-34
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Publication
15078142 | -
First Author: Stout TJ
Year: 2004
Journal: Curr Pharm Des
Title: High-throughput structural biology in drug discovery: protein kinases.
Volume: 10
Issue: 10
Pages: 1069-82
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Publication
15320712 | -
First Author: Li B
Year: 2004
Journal: Comb Chem High Throughput Screen
Title: Creating chemical diversity to target protein kinases.
Volume: 7
Issue: 5
Pages: 453-72
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