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Search results 401 to 500 out of 1209 for Itch

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Type Details Score
Publication
29988128 | J:268042
First Author: Huang CC
Year: 2018
Journal: Nat Med
Title: Anatomical and functional dichotomy of ocular itch and pain.
Volume: 24
Issue: 8
Pages: 1268-1276
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Publication
30450838 | J:309121
First Author: Zschiebsch K
Year: 2019
Journal: J Cell Mol Med
Title: Mast cell tetrahydrobiopterin contributes to itch in mice.
Volume: 23
Issue: 2
Pages: 985-1000
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Publication
35299695 | J:358719
 
First Author: Li J
Year: 2022
Journal: Front Mol Neurosci
Title: Parvalbumin Neurons in Zona Incerta Regulate Itch in Mice.
Volume: 15
Pages: 843754
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Publication
23524965 | J:197626
First Author: Alemi F
Year: 2013
Journal: J Clin Invest
Title: The TGR5 receptor mediates bile acid-induced itch and analgesia.
Volume: 123
Issue: 4
Pages: 1513-30
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Publication
31883963 | J:291036
First Author: Guo CJ
Year: 2020
Journal: J Invest Dermatol
Title: Kallikrein 7 Promotes Atopic Dermatitis-Associated Itch Independently of Skin Inflammation.
Volume: 140
Issue: 6
Pages: 1244-1252.e4
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Publication
38485252 | J:358850
 
First Author: Chen S
Year: 2024
Journal: Mol Pain
Title: Mechanical and chemical itch regulated by neuropeptide Y-Y(1) signaling.
Volume: 20
Pages: 17448069241242982
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Publication
29424270 | J:278209
 
First Author: Duo L
Year: 2018
Journal: Mol Pain
Title: TRPV1 gain-of-function mutation impairs pain and itch sensations in mice.
Volume: 14
Pages: 1744806918762031
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Publication
32165318 | J:299465
First Author: Yin Q
Year: 2020
Journal: Semin Cancer Biol
Title: ITCH as a potential therapeutic target in human cancers.
Volume: 67
Issue: Pt 2
Pages: 117-130
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Publication
35996084 | J:347236
First Author: Kaneko T
Year: 2022
Journal: J Physiol Sci
Title: Hypothalamic orexinergic neurons modulate pain and itch in an opposite way: pain relief and itch exacerbation.
Volume: 72
Issue: 1
Pages: 21
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Publication
33819485 | J:311631
First Author: Chen Y
Year: 2021
Journal: Gastroenterology
Title: Epithelia-Sensory Neuron Cross Talk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine.
Volume: 161
Issue: 1
Pages: 301-317.e16
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DO Term
DOID:8295 | scabies
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Publication
29309986 | J:345379
 
First Author: Mentrup HL
Year: 2018
Journal: Differentiation
Title: The ubiquitin ligase ITCH coordinates small intestinal epithelial homeostasis by modulating cell proliferation, differentiation, and migration.
Volume: 99
Pages: 51-61
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Publication
21775281 | J:259090
First Author: Liu Q
Year: 2011
Journal: Sci Signal
Title: The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia.
Volume: 4
Issue: 181
Pages: ra45
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Publication
33358893 | J:329699
First Author: Li X
Year: 2021
Journal: J Allergy Clin Immunol
Title: Tick peptides evoke itch by activating MrgprC11/MRGPRX1 to sensitize TRPV1 in pruriceptors.
Volume: 147
Issue: 6
Pages: 2236-2248.e16
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Publication
32015563 | J:284739
First Author: Alvaro CG
Year: 2020
Journal: PLoS One
Title: Hippocalcin-like 4, a neural calcium sensor, has a limited contribution to pain and itch processing.
Volume: 15
Issue: 2
Pages: e0226289
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Publication
37863387 | J:343527
     
First Author: Ahn JW
Year: 2023
Journal: J Invest Dermatol
Title: Cav3.2 T-Type Calcium Channel Mediates Acute Itch and Contributes to Chronic Itch and Inflammation in Experimental Atopic Dermatitis.
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Publication
31787267 | J:352856
First Author: Koga K
Year: 2020
Journal: J Allergy Clin Immunol
Title: Sensitization of spinal itch transmission neurons in a mouse model of chronic itch requires an astrocytic factor.
Volume: 145
Issue: 1
Pages: 183-191.e10
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Publication
22000021 | J:177501
First Author: Liu XY
Year: 2011
Journal: Cell
Title: Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids.
Volume: 147
Issue: 2
Pages: 447-58
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Publication
37995657 | J:343323
First Author: Deng L
Year: 2023
Journal: Cell
Title: S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis.
Volume: 186
Issue: 24
Pages: 5375-5393.e25
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Publication
29669290 | J:264867
First Author: Munanairi A
Year: 2018
Journal: Cell Rep
Title: Non-canonical Opioid Signaling Inhibits Itch Transmission in the Spinal Cord of Mice.
Volume: 23
Issue: 3
Pages: 866-877
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Publication
25453842 | J:218757
First Author: Zhao ZQ
Year: 2014
Journal: Neuron
Title: Descending control of itch transmission by the serotonergic system via 5-HT1A-facilitated GRP-GRPR signaling.
Volume: 84
Issue: 4
Pages: 821-34
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Publication
28231466 | J:249930
First Author: Sun S
Year: 2017
Journal: Neuron
Title: Leaky Gate Model: Intensity-Dependent Coding of Pain and Itch in the Spinal Cord.
Volume: 93
Issue: 4
Pages: 840-853.e5
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Publication
29556030 | J:264635
First Author: Huang J
Year: 2018
Journal: Nat Neurosci
Title: Circuit dissection of the role of somatostatin in itch and pain.
Volume: 21
Issue: 5
Pages: 707-716
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Publication
26516282 | J:226610
First Author: Bourane S
Year: 2015
Journal: Science
Title: Gate control of mechanical itch by a subpopulation of spinal cord interneurons.
Volume: 350
Issue: 6260
Pages: 550-4
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Publication
34032210 | J:307165
   
First Author: Samineni VK
Year: 2021
Journal: Elife
Title: Cellular, circuit and transcriptional framework for modulation of itch in the central amygdala.
Volume: 10
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Publication
37224813 | J:339583
First Author: Pan Q
Year: 2023
Journal: Neuron
Title: Representation and control of pain and itch by distinct prefrontal neural ensembles.
Volume: 111
Issue: 15
Pages: 2414-2431.e7
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Publication
37490401 | J:349732
   
First Author: Boyle KA
Year: 2023
Journal: Elife
Title: Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling.
Volume: 12
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Publication
- | J:288162
     
First Author: Barry DM
Year: 2018
Journal: bioRxiv
Title: Exploration of Sensory and Spinal Neurons Expressing GRP in Itch and Pain.
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Publication
32298640 | J:296179
First Author: Sharif B
Year: 2020
Journal: Neuron
Title: Differential Coding of Itch and Pain by a Subpopulation of Primary Afferent Neurons.
Volume: 106
Issue: 6
Pages: 940-951.e4
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Publication
33536279 | J:302044
 
First Author: Nguyen E
Year: 2021
Journal: Sci Transl Med
Title: Morphine acts on spinal dynorphin neurons to cause itch through disinhibition.
Volume: 13
Issue: 579
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Publication
35705043 | J:351460
First Author: Gao Y
Year: 2022
Journal: Cell Rep
Title: TRPV1 SUMOylation suppresses itch by inhibiting TRPV1 interaction with H1 receptors.
Volume: 39
Issue: 11
Pages: 110972
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Publication
26521042 | J:273164
First Author: Huang CC
Year: 2016
Journal: J Allergy Clin Immunol
Title: A histamine-independent itch pathway is required for allergic ocular itch.
Volume: 137
Issue: 4
Pages: 1267-1270.e6
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Publication
31167004 | J:277275
First Author: Bartsch VB
Year: 2019
Journal: PLoS One
Title: Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice.
Volume: 14
Issue: 6
Pages: e0217819
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Publication
33035568 | J:322085
First Author: Larkin C
Year: 2021
Journal: J Allergy Clin Immunol
Title: Novel insights into the TRPV3-mediated itch in atopic dermatitis.
Volume: 147
Issue: 3
Pages: 1110-1114.e5
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Publication
17653196 | J:123810
First Author: Sun YG
Year: 2007
Journal: Nature
Title: A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord.
Volume: 448
Issue: 7154
Pages: 700-3
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Publication
25209280 | J:216292
First Author: Zhao ZQ
Year: 2014
Journal: J Neurosci
Title: Cross-inhibition of NMBR and GRPR signaling maintains normal histaminergic itch transmission.
Volume: 34
Issue: 37
Pages: 12402-14
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Publication
22168443 | J:323415
 
First Author: Lee B
Year: 2011
Journal: Mol Pain
Title: Genetic enhancement of behavioral itch responses in mice lacking phosphoinositide 3-kinase-γ (PI3Kγ).
Volume: 7
Pages: 96
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Publication
28134655 | J:276627
First Author: Pandey M
Year: 2017
Journal: Pain
Title: A central role for R7bp in the regulation of itch sensation.
Volume: 158
Issue: 5
Pages: 931-944
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Publication
37522391 | J:350963
First Author: Zhang ZJ
Year: 2023
Journal: EMBO Rep
Title: Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR(+) neurons.
Volume: 24
Issue: 10
Pages: e56098
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Publication
28157737 | J:247582
First Author: Aresh B
Year: 2017
Journal: Pain
Title: Spinal cord interneurons expressing the gastrin-releasing peptide receptor convey itch through VGLUT2-mediated signaling.
Volume: 158
Issue: 5
Pages: 945-961
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Publication
31047975 | J:283004
 
First Author: Jurcakova D
Year: 2019
Journal: Neuroscience
Title: Allergen-induced histaminergic and non-histaminergic activation of itch C-fiber nerve terminals in mouse skin.
Volume: 410
Pages: 55-58
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Publication
20170897 | J:158777
First Author: Lohr NJ
Year: 2010
Journal: Am J Hum Genet
Title: Human ITCH E3 ubiquitin ligase deficiency causes syndromic multisystem autoimmune disease.
Volume: 86
Issue: 3
Pages: 447-53
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Publication
32895292 | J:297045
First Author: Sakai K
Year: 2020
Journal: J Neurosci
Title: Low-Threshold Mechanosensitive VGLUT3-Lineage Sensory Neurons Mediate Spinal Inhibition of Itch by Touch.
Volume: 40
Issue: 40
Pages: 7688-7701
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Publication
33172979 | J:303187
First Author: Dong F
Year: 2020
Journal: J Neurosci
Title: FGF13 Is Required for Histamine-Induced Itch Sensation by Interaction with NaV1.7.
Volume: 40
Issue: 50
Pages: 9589-9601
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Publication
20346763 | J:158273
First Author: Ross SE
Year: 2010
Journal: Neuron
Title: Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice.
Volume: 65
Issue: 6
Pages: 886-98
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Publication
30734045 | J:322388
First Author: Ehling S
Year: 2019
Journal: Acta Derm Venereol
Title: Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons.
Volume: 99
Issue: 6
Pages: 587-893
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Publication
32032577 | J:293863
First Author: Liu X
Year: 2020
Journal: J Invest Dermatol
Title: Spinal GRPR and NPRA Contribute to Chronic Itch in a Murine Model of Allergic Contact Dermatitis.
Volume: 140
Issue: 9
Pages: 1856-1866.e7
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Publication
24726382 | J:213645
First Author: Kardon AP
Year: 2014
Journal: Neuron
Title: Dynorphin acts as a neuromodulator to inhibit itch in the dorsal horn of the spinal cord.
Volume: 82
Issue: 3
Pages: 573-86
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Publication
33077777 | J:298285
First Author: Gonzales-Rojas R
Year: 2020
Journal: Sci Rep
Title: The mouse model of fragile X syndrome exhibits deficits in contagious itch behavior.
Volume: 10
Issue: 1
Pages: 17679
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Publication
26440887 | J:315854
First Author: Peng Z
Year: 2015
Journal: Cell Rep
Title: ASIC3 Mediates Itch Sensation in Response to Coincident Stimulation by Acid and Nonproton Ligand.
Volume: 13
Issue: 2
Pages: 387-98
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Publication
30104684 | J:267282
First Author: Ralvenius WT
Year: 2018
Journal: Nat Commun
Title: Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors.
Volume: 9
Issue: 1
Pages: 3230
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Publication
32170060 | J:286744
First Author: Barry DM
Year: 2020
Journal: Nat Commun
Title: Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors.
Volume: 11
Issue: 1
Pages: 1397
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Publication
35106466 | J:351068
First Author: Liu PF
Year: 2022
Journal: iScience
Title: Modulation of itch and pain signals processing in ventrobasal thalamus by thalamic reticular nucleus.
Volume: 25
Issue: 1
Pages: 103625
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Publication
23523592 | J:197911
First Author: McCoy ES
Year: 2013
Journal: Neuron
Title: Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold.
Volume: 78
Issue: 1
Pages: 138-51
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Publication
31554789 | J:279475
First Author: Samineni VK
Year: 2019
Journal: Nat Commun
Title: Cell type-specific modulation of sensory and affective components of itch in the periaqueductal gray.
Volume: 10
Issue: 1
Pages: 4356
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Publication
23578956 | J:331298
First Author: O'Brien DE
Year: 2013
Journal: J Pain
Title: Assessment of pain and itch behavior in a mouse model of neurofibromatosis type 1.
Volume: 14
Issue: 6
Pages: 628-37
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Publication
33130130 | J:304601
 
First Author: Kelemen B
Year: 2021
Journal: Biochem Pharmacol
Title: The TRPM3 ion channel mediates nociception but not itch evoked by endogenous pruritogenic mediators.
Volume: 183
Pages: 114310
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Publication
37392090 | J:342669
First Author: Yang Y
Year: 2023
Journal: Glia
Title: Microglia are involved in regulating histamine-dependent and non-dependent itch transmissions with distinguished signal pathways.
Volume: 71
Issue: 11
Pages: 2541-2558
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Publication
38553047 | J:352231
 
First Author: Weman HM
Year: 2024
Journal: J Neurosci
Title: Spinal Glycine Receptor Alpha 3 Cells Communicate Sensations of Chemical Itch in Hairy Skin.
Volume: 44
Issue: 19
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Publication
27436359 | J:259342
First Author: Kim S
Year: 2016
Journal: Sci Signal
Title: Facilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populations.
Volume: 9
Issue: 437
Pages: ra71
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Publication
27899527 | J:260327
First Author: Brust TF
Year: 2016
Journal: Sci Signal
Title: Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria.
Volume: 9
Issue: 456
Pages: ra117
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Publication
28745101 | J:322095
 
First Author: Jiang YM
Year: 2017
Journal: Mol Pain
Title: Acidosis counteracts itch tachyphylaxis to consecutive pruritogen exposure dependent on acid-sensing ion channel 3.
Volume: 13
Pages: 1744806917721114
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Publication
28701920 | J:288832
 
First Author: Huang C
Year: 2017
Journal: Front Mol Neurosci
Title: Tlx3 Function in the Dorsal Root Ganglion is Pivotal to Itch and Pain Sensations.
Volume: 10
Pages: 205
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Publication
31197234 | J:279034
First Author: Takahashi S
Year: 2019
Journal: Sci Rep
Title: Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development.
Volume: 9
Issue: 1
Pages: 8625
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Publication
33109226 | J:303367
First Author: Koga K
Year: 2020
Journal: Mol Brain
Title: Intrinsic braking role of descending locus coeruleus noradrenergic neurons in acute and chronic itch in mice.
Volume: 13
Issue: 1
Pages: 144
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Publication
28401489 | J:336484
First Author: Jing PB
Year: 2018
Journal: Neurosci Bull
Title: Chemokine Receptor CXCR3 in the Spinal Cord Contributes to Chronic Itch in Mice.
Volume: 34
Issue: 1
Pages: 54-63
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Publication
20818436 | J:175332
First Author: Di Marcotullio L
Year: 2011
Journal: Oncogene
Title: Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal.
Volume: 30
Issue: 1
Pages: 65-76
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Publication
26874069 | J:230862
 
First Author: Tang M
Year: 2016
Journal: Brain Res
Title: Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons.
Volume: 1636
Pages: 161-71
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Publication
38098939 | J:343685
 
First Author: Takanami K
Year: 2023
Journal: Front Mol Neurosci
Title: Function of gastrin-releasing peptide receptors in ocular itch transmission in the mouse trigeminal sensory system.
Volume: 16
Pages: 1280024
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Publication
30655357 | J:273606
First Author: Albisetti GW
Year: 2019
Journal: J Neurosci
Title: Dorsal Horn Gastrin-Releasing Peptide Expressing Neurons Transmit Spinal Itch But Not Pain Signals.
Volume: 39
Issue: 12
Pages: 2238-2250
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Publication
37516088 | J:348015
 
First Author: Yang YY
Year: 2023
Journal: Phytomedicine
Title: Antipruritic effects of geraniol on acute and chronic itch via modulating spinal GABA/GRPR signaling.
Volume: 119
Pages: 154969
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Publication
28176353 | J:326304
First Author: Kittaka H
Year: 2017
Journal: J Physiol
Title: Lysophosphatidic acid-induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1.
Volume: 595
Issue: 8
Pages: 2681-2698
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Publication
36241382 | J:353052
First Author: Liang TY
Year: 2022
Journal: J Neurosci
Title: Distinct Roles of Dopamine Receptor Subtypes in the Nucleus Accumbens during Itch Signal Processing.
Volume: 42
Issue: 47
Pages: 8842-8854
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Publication
36937045 | J:345217
 
First Author: Zhou GK
Year: 2023
Journal: Front Mol Neurosci
Title: Acid-sensing ion channel 3 is required for agmatine-induced histamine-independent itch in mice.
Volume: 16
Pages: 1086285
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Publication
24549959 | J:346363
First Author: Qu L
Year: 2014
Journal: Brain
Title: Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain.
Volume: 137
Issue: Pt 4
Pages: 1039-50
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Publication
26216096 | J:224443
 
First Author: Reddy VB
Year: 2015
Journal: Nat Commun
Title: Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs.
Volume: 6
Pages: 7864
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Publication
30341332 | J:268167
First Author: Melo H
Year: 2018
Journal: Sci Rep
Title: Itch induced by peripheral mu opioid receptors is dependent on TRPV1-expressing neurons and alleviated by channel activation.
Volume: 8
Issue: 1
Pages: 15551
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Publication
32289348 | J:297486
First Author: Lee SH
Year: 2020
Journal: J Invest Dermatol
Title: Sensory Neuron-Expressed TRPC4 Is a Target for the Relief of Psoriasiform Itch and Skin Inflammation in Mice.
Volume: 140
Issue: 11
Pages: 2221-2229.e6
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Publication
33726812 | J:307947
First Author: Shiraishi Y
Year: 2021
Journal: Mol Brain
Title: α1A-adrenaline receptors in dorsal horn inhibitory neurons have an inhibitory role in the regulation of chloroquine-induced itch in mice.
Volume: 14
Issue: 1
Pages: 55
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Publication
29094727 | J:271888
First Author: Cui TT
Year: 2018
Journal: Acta Pharmacol Sin
Title: A pivotal role for the activation of TRPV3 channel in itch sensations induced by the natural skin sensitizer carvacrol.
Volume: 39
Issue: 3
Pages: 331-335
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Interaction Experiment
Kathania M (2016)
Description: Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-t ubiquitination.
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Publication
31141156 | J:289289
First Author: Hashimoto T
Year: 2019
Journal: Acta Derm Venereol
Title: Signal Transducer and Activator of Transcription 3 in Keratinocytes Regulates Histaminergic Itch but Not Nonhistaminergic Itch.
Volume: 99
Issue: 10
Pages: 901-902
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Publication
31405606 | J:305132
First Author: Sakata D
Year: 2019
Journal: J Allergy Clin Immunol
Title: Selective role of neurokinin B in IL-31-induced itch response in mice.
Volume: 144
Issue: 4
Pages: 1130-1133.e8
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Publication
32817686 | J:293872
First Author: Ebbinghaus M
Year: 2020
Journal: PLoS One
Title: Gain-of-function mutation in SCN11A causes itch and affects neurogenic inflammation and muscle function in Scn11a+/L799P mice.
Volume: 15
Issue: 8
Pages: e0237101
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Publication
34716234 | J:333010
First Author: Chen XJ
Year: 2021
Journal: J Neurosci
Title: Multiplexed Representation of Itch and Mechanical and Thermal Sensation in the Primary Somatosensory Cortex.
Volume: 41
Issue: 50
Pages: 10330-10340
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Publication
25194674 | J:315341
First Author: Lieu T
Year: 2014
Journal: Gastroenterology
Title: The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice.
Volume: 147
Issue: 6
Pages: 1417-28
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Publication
31285762 | J:295516
First Author: Cheng RX
Year: 2019
Journal: Theranostics
Title: The role of Nav1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes.
Volume: 9
Issue: 15
Pages: 4287-4307
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Publication
27821781 | J:239108
First Author: Liu B
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy.
Volume: 113
Issue: 47
Pages: E7572-E7579
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Publication
35095413 | J:319731
 
First Author: Hu Y
Year: 2021
Journal: Front Mol Neurosci
Title: The Role of Transient Receptor Potential A1 and G Protein-Coupled Receptor 39 in Zinc-Mediated Acute and Chronic Itch in Mice.
Volume: 14
Pages: 768731
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Publication
20392206 | J:163431
First Author: Azakir BA
Year: 2010
Journal: FEBS J
Title: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid.
Volume: 277
Issue: 5
Pages: 1319-30
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Publication
17185983 | J:121569
First Author: Bigliardi-Qi M
Year: 2007
Journal: J Invest Dermatol
Title: Deletion of mu- and kappa-opioid receptors in mice changes epidermal hypertrophy, density of peripheral nerve endings, and itch behavior.
Volume: 127
Issue: 6
Pages: 1479-88
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Publication
32241803 | J:297165
First Author: Mona B
Year: 2020
Journal: Genes Dev
Title: Positive autofeedback regulation of Ptf1a transcription generates the levels of PTF1A required to generate itch circuit neurons.
Volume: 34
Issue: 9-10
Pages: 621-636
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Publication
35095512 | J:319740
 
First Author: Wang W
Year: 2021
Journal: Front Pharmacol
Title: Paeonol Ameliorates Chronic Itch and Spinal Astrocytic Activation via CXCR3 in an Experimental Dry Skin Model in Mice.
Volume: 12
Pages: 805222
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Publication
23271050 | J:197648
First Author: Fernandes ES
Year: 2013
Journal: FASEB J
Title: Superoxide generation and leukocyte accumulation: key elements in the mediation of leukotriene B₄-induced itch by transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1.
Volume: 27
Issue: 4
Pages: 1664-73
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Publication
21300878 | J:169300
First Author: Kim SJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons.
Volume: 108
Issue: 8
Pages: 3371-6
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Allele
Itch<em1Smoc> | MGI:7290593
Name: itchy, E3 ubiquitin protein ligase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Yang C (2006)
Description: Negative regulation of the E3 ubiquitin ligase itch via Fyn-mediated tyrosine phosphorylation.
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Interaction Experiment
Chang L (2006)
Description: The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover.
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Interaction Experiment
Ahmed N (2011)
Description: The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.
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Interaction Experiment
Bai Y (2004)
Description: Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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