|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 401 to 500 out of 3295 for Kras

<< First    < Previous  |  Next >    Last >>
0.054s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
23943799 | J:202615
First Author: Licciulli S
Year: 2013
Journal: Cancer Res
Title: Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53.
Volume: 73
Issue: 19
Pages: 5974-84
•
•
•
•
•
Publication
18316617 | J:132860
First Author: Hegedus B
Year: 2008
Journal: Cancer Res
Title: Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.
Volume: 68
Issue: 5
Pages: 1520-8
•
•
•
•
•
Publication
26677984 | J:295895
First Author: Choi E
Year: 2016
Journal: Gastroenterology
Title: Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions.
Volume: 150
Issue: 4
Pages: 918-30.e13
•
•
•
•
•
Publication
32994205 | J:299180
First Author: Garg R
Year: 2020
Journal: Cancer Res
Title: PKCε Is Required for KRAS-Driven Lung Tumorigenesis.
Volume: 80
Issue: 23
Pages: 5166-5173
•
•
•
•
•
Publication
26965285 | J:231912
First Author: Akutagawa J
Year: 2016
Journal: Leukemia
Title: Targeting the PI3K/Akt pathway in murine MDS/MPN driven by hyperactive Ras.
Volume: 30
Issue: 6
Pages: 1335-43
•
•
•
•
•
Publication
30130254 | J:271237
First Author: Taparra K
Year: 2018
Journal: J Clin Invest
Title: O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis.
Volume: 128
Issue: 11
Pages: 4924-4937
•
•
•
•
•
Publication
22654667 | J:185196
First Author: Tran PT
Year: 2012
Journal: PLoS Genet
Title: Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.
Volume: 8
Issue: 5
Pages: e1002650
•
•
•
•
•
Publication
24315826 | J:302666
First Author: Collins MA
Year: 2014
Journal: Gastroenterology
Title: MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice.
Volume: 146
Issue: 3
Pages: 822-834.e7
•
•
•
•
•
Publication
17804724 | J:124882
First Author: Kojima K
Year: 2007
Journal: Cancer Res
Title: Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia.
Volume: 67
Issue: 17
Pages: 8121-30
•
•
•
•
•
Publication
22751123 | J:198022
First Author: Maier HJ
Year: 2013
Journal: Oncogene
Title: Requirement of NEMO/IKKγ for effective expansion of KRAS-induced precancerous lesions in the pancreas.
Volume: 32
Issue: 21
Pages: 2690-5
•
•
•
•
•
Publication
24788257 | J:216102
First Author: Morris JP 4th
Year: 2014
Journal: PLoS One
Title: Dicer regulates differentiation and viability during mouse pancreatic cancer initiation.
Volume: 9
Issue: 5
Pages: e95486
•
•
•
•
•
Publication
17591971 | J:122825
First Author: Zhu L
Year: 2007
Journal: Am J Pathol
Title: Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia.
Volume: 171
Issue: 1
Pages: 263-73
•
•
•
•
•
Publication
38731942 | J:348373
 
First Author: Liou GY
Year: 2024
Journal: Int J Mol Sci
Title: Cytokine CCL9 Mediates Oncogenic KRAS-Induced Pancreatic Acinar-to-Ductal Metaplasia by Promoting Reactive Oxygen Species and Metalloproteinases.
Volume: 25
Issue: 9
•
•
•
•
•
Publication
28886117 | J:344810
First Author: Chang HH
Year: 2017
Journal: PLoS One
Title: Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice.
Volume: 12
Issue: 9
Pages: e0184455
•
•
•
•
•
Publication
21285251 | J:170354
First Author: Sureban SM
Year: 2011
Journal: Cancer Res
Title: DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism.
Volume: 71
Issue: 6
Pages: 2328-38
•
•
•
•
•
Publication
25248858 | J:264392
First Author: Mohammed A
Year: 2014
Journal: Cancer Prev Res (Phila)
Title: Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.
Volume: 7
Issue: 12
Pages: 1198-209
•
•
•
•
•
Publication
26574479 | J:226829
First Author: Momcilovic M
Year: 2015
Journal: Cancer Res
Title: Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers.
Volume: 75
Issue: 22
Pages: 4910-22
•
•
•
•
•
Publication
34635508 | J:322316
First Author: Dey S
Year: 2022
Journal: Mol Cancer Res
Title: Heme Sequestration Effectively Suppresses the Development and Progression of Both Lung Adenocarcinoma and Squamous Cell Carcinoma.
Volume: 20
Issue: 1
Pages: 139-149
•
•
•
•
•
Publication
24902898 | J:229998
First Author: Grasso D
Year: 2014
Journal: Cell Death Differ
Title: Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescence.
Volume: 21
Issue: 10
Pages: 1633-41
•
•
•
•
•
Publication
19662677 | J:152717
First Author: Kim WY
Year: 2009
Journal: J Clin Invest
Title: HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice.
Volume: 119
Issue: 8
Pages: 2160-70
•
•
•
•
•
Publication
30833304 | J:286004
 
First Author: Saad MI
Year: 2019
Journal: EMBO Mol Med
Title: ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer.
Volume: 11
Issue: 4
•
•
•
•
•
Publication
25361845 | J:325277
First Author: Liou GY
Year: 2015
Journal: Cancer Discov
Title: Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions.
Volume: 5
Issue: 1
Pages: 52-63
•
•
•
•
•
Publication
20972333 | J:167562
First Author: Vicent S
Year: 2010
Journal: J Clin Invest
Title: Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.
Volume: 120
Issue: 11
Pages: 3940-52
•
•
•
•
•
Publication
22509024 | J:183916
First Author: Kang R
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia.
Volume: 109
Issue: 18
Pages: 7031-6
•
•
•
•
•
Publication
34156985 | J:310404
 
First Author: Homayun-Sepehr N
Year: 2021
Journal: JCI Insight
Title: KRAS-driven model of Gorham-Stout disease effectively treated with trametinib.
Volume: 6
Issue: 15
•
•
•
•
•
Publication
26516699 | J:316707
First Author: Rachagani S
Year: 2015
Journal: Oncotarget
Title: Changes in microRNA (miRNA) expression during pancreatic cancer development and progression in a genetically engineered KrasG12D;Pdx1-Cre mouse (KC) model.
Volume: 6
Issue: 37
Pages: 40295-309
•
•
•
•
•
Publication
36635501 | J:348732
First Author: Tang R
Year: 2023
Journal: Nat Cell Biol
Title: Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth.
Volume: 25
Issue: 1
Pages: 159-169
•
•
•
•
•
Publication
23578383 | J:198521
First Author: Al Saati T
Year: 2013
Journal: Am J Pathol
Title: Oxidative stress induced by inactivation of TP53INP1 cooperates with KrasG12D to initiate and promote pancreatic carcinogenesis in the murine pancreas.
Volume: 182
Issue: 6
Pages: 1996-2004
•
•
•
•
•
Publication
32709695 | J:348810
 
First Author: Mallya K
Year: 2020
Journal: Biol Open
Title: Acinar transformed ductal cells exhibit differential mucin expression in a tamoxifen-induced pancreatic ductal adenocarcinoma mouse model.
Volume: 9
Issue: 9
•
•
•
•
•
Publication
32029896 | J:291130
First Author: Li JT
Year: 2020
Journal: Nat Cell Biol
Title: BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma.
Volume: 22
Issue: 2
Pages: 167-174
•
•
•
•
•
Publication
30008881 | J:299376
First Author: Noguchi K
Year: 2018
Journal: Oncol Lett
Title: c-Met affects gemcitabine resistance during carcinogenesis in a mouse model of pancreatic cancer.
Volume: 16
Issue: 2
Pages: 1892-1898
•
•
•
•
•
Publication
32541781 | J:296715
First Author: Hidalgo-Sastre A
Year: 2020
Journal: Sci Rep
Title: Mir34a constrains pancreatic carcinogenesis.
Volume: 10
Issue: 1
Pages: 9654
•
•
•
•
•
Publication
31534627 | J:298180
First Author: Ueda Y
Year: 2019
Journal: Oncotarget
Title: Application of C. elegans cancer screening test for the detection of pancreatic tumor in genetically engineered mice.
Volume: 10
Issue: 52
Pages: 5412-5418
•
•
•
•
•
Publication
38654064 | J:348256
First Author: Wiley MB
Year: 2024
Journal: Sci Rep
Title: Activin A signaling stimulates neutrophil activation and macrophage migration in pancreatitis.
Volume: 14
Issue: 1
Pages: 9382
•
•
•
•
•
Publication
38834136 | J:349887
 
First Author: Rogers JH
Year: 2024
Journal: Exp Hematol
Title: Dose-dependent effects of Dnmt3a in an inducible murine model of Kras(G12D)-driven leukemia.
Volume: 135
Pages: 104248
•
•
•
•
•
Publication
21311774 | J:170906
First Author: Ray KC
Year: 2011
Journal: PLoS One
Title: Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model.
Volume: 6
Issue: 2
Pages: e16786
•
•
•
•
•
Publication
33891893 | J:328621
First Author: Hill W
Year: 2021
Journal: Curr Biol
Title: EPHA2-dependent outcompetition of KRASG12D mutant cells by wild-type neighbors in the adult pancreas.
Volume: 31
Issue: 12
Pages: 2550-2560.e5
•
•
•
•
•
Publication
21984419 | J:183335
First Author: Aichler M
Year: 2012
Journal: J Pathol
Title: Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.
Volume: 226
Issue: 5
Pages: 723-34
•
•
•
•
•
Publication
31000598 | J:275811
First Author: Lim JKM
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.
Volume: 116
Issue: 19
Pages: 9433-9442
•
•
•
•
•
Publication
25341034 | J:318256
 
First Author: Kang R
Year: 2014
Journal: Cell Death Dis
Title: RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer.
Volume: 5
Pages: e1480
•
•
•
•
•
Publication
36538983 | J:332974
 
First Author: Yang J
Year: 2023
Journal: Cancer Lett
Title: Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10.
Volume: 555
Pages: 216025
•
•
•
•
•
Publication
37730692 | J:340789
First Author: Baltanás FC
Year: 2023
Journal: Nat Commun
Title: Critical requirement of SOS1 for tumor development and microenvironment modulation in KRAS(G12D)-driven lung adenocarcinoma.
Volume: 14
Issue: 1
Pages: 5856
•
•
•
•
•
Publication
37643866 | J:340295
 
First Author: Spaan CN
Year: 2023
Journal: Life Sci Alliance
Title: Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis.
Volume: 6
Issue: 11
•
•
•
•
•
Publication
39213022 | J:361505
   
First Author: Ghazi PC
Year: 2024
Journal: Elife
Title: Inhibition of ULK1/2 and KRAS(G12C) controls tumor growth in preclinical models of lung cancer.
Volume: 13
•
•
•
•
•
Publication
22022614 | J:179772
First Author: Regala RP
Year: 2011
Journal: PLoS One
Title: Matrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formation.
Volume: 6
Issue: 10
Pages: e26439
•
•
•
•
•
Publication
38272100 | J:346390
     
First Author: Won Y
Year: 2024
Journal: Gastroenterology
Title: Oncogenic Fatty Acid Metabolism Rewires Energy Supply Chain in Gastric Carcinogenesis.
•
•
•
•
•
Publication
21512139 | J:172206
First Author: Young NP
Year: 2011
Journal: Cancer Res
Title: Uncoupling cancer mutations reveals critical timing of p53 loss in sarcomagenesis.
Volume: 71
Issue: 11
Pages: 4040-7
•
•
•
•
•
Publication
22897852 | J:191822
First Author: Maraver A
Year: 2012
Journal: Cancer Cell
Title: Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK.
Volume: 22
Issue: 2
Pages: 222-34
•
•
•
•
•
Publication
26973251 | J:235984
First Author: Bigi A
Year: 2016
Journal: Oncogene
Title: Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis.
Volume: 35
Issue: 39
Pages: 5132-43
•
•
•
•
•
Publication
24264992 | J:205193
First Author: Vermeulen L
Year: 2013
Journal: Science
Title: Defining stem cell dynamics in models of intestinal tumor initiation.
Volume: 342
Issue: 6161
Pages: 995-8
•
•
•
•
•
Publication
34079126 | J:322623
First Author: Yum MK
Year: 2021
Journal: Nature
Title: Tracing oncogene-driven remodelling of the intestinal stem cell niche.
Volume: 594
Issue: 7863
Pages: 442-447
•
•
•
•
•
Publication
36351408 | J:331107
First Author: Ramakrishnan G
Year: 2022
Journal: Cell Rep
Title: NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 6
Pages: 111623
•
•
•
•
•
Publication
30013058 | J:266243
First Author: Grzeskowiak CL
Year: 2018
Journal: Nat Commun
Title: In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.
Volume: 9
Issue: 1
Pages: 2732
•
•
•
•
•
Publication
29334357 | J:256834
   
First Author: Chua CW
Year: 2018
Journal: Elife
Title: Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation.
Volume: 7
•
•
•
•
•
Publication
24097820 | J:205411
First Author: Zhang Y
Year: 2013
Journal: Cancer Res
Title: Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.
Volume: 73
Issue: 20
Pages: 6359-74
•
•
•
•
•
Publication
17676052 | J:125101
First Author: Kirsch DG
Year: 2007
Journal: Nat Med
Title: A spatially and temporally restricted mouse model of soft tissue sarcoma.
Volume: 13
Issue: 8
Pages: 992-7
•
•
•
•
•
Publication
33414552 | J:302321
First Author: Najumudeen AK
Year: 2021
Journal: Nat Genet
Title: The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
Volume: 53
Issue: 1
Pages: 16-26
•
•
•
•
•
Publication
36516772 | J:332395
First Author: Sessions DT
Year: 2022
Journal: Cell Rep
Title: Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD(+) regeneration in KRas-mutant lung adenocarcinoma.
Volume: 41
Issue: 11
Pages: 111818
•
•
•
•
•
Publication
24561622 | J:212984
First Author: von Figura G
Year: 2014
Journal: Nat Cell Biol
Title: The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma.
Volume: 16
Issue: 3
Pages: 255-67
•
•
•
•
•
Publication
26091037 | J:223512
First Author: Dow LE
Year: 2015
Journal: Cell
Title: Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer.
Volume: 161
Issue: 7
Pages: 1539-1552
•
•
•
•
•
Publication
31266893 | J:278206
First Author: Torres C
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: p110γ deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity.
Volume: 116
Issue: 29
Pages: 14724-14733
•
•
•
•
•
Publication
30938713 | J:308939
   
First Author: Cruz VH
Year: 2019
Journal: JCI Insight
Title: Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer.
Volume: 5
•
•
•
•
•
Publication
31801083 | J:296787
First Author: Li H
Year: 2019
Journal: Cell Rep
Title: YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression.
Volume: 29
Issue: 10
Pages: 3200-3211.e4
•
•
•
•
•
Publication
37774698 | J:341369
First Author: Zhu M
Year: 2023
Journal: Cancer Cell
Title: Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden.
Volume: 41
Issue: 10
Pages: 1731-1748.e8
•
•
•
•
•
Publication
27174785 | J:241552
First Author: Hernández-Porras I
Year: 2016
Journal: J Pathol
Title: K-Ras(V14I) -induced Noonan syndrome predisposes to tumour development in mice.
Volume: 239
Issue: 2
Pages: 206-17
•
•
•
•
•
Publication
35120601 | J:320538
First Author: Alam A
Year: 2022
Journal: Cancer Cell
Title: Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer.
Volume: 40
Issue: 2
Pages: 153-167.e11
•
•
•
•
•
Publication
36477656 | J:332124
First Author: Flanagan DJ
Year: 2022
Journal: Nat Commun
Title: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Volume: 13
Issue: 1
Pages: 7551
•
•
•
•
•
Publication
26585400 | J:227252
First Author: Hayakawa Y
Year: 2015
Journal: Cancer Cell
Title: Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche.
Volume: 28
Issue: 6
Pages: 800-814
•
•
•
•
•
Publication
21536023 | J:173640
First Author: Qu X
Year: 2011
Journal: Dev Biol
Title: Genetic epistasis between heparan sulfate and FGF-Ras signaling controls lens development.
Volume: 355
Issue: 1
Pages: 12-20
•
•
•
•
•
Publication
36001969 | J:328042
First Author: Wang T
Year: 2022
Journal: Cell Rep
Title: The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations.
Volume: 40
Issue: 8
Pages: 111210
•
•
•
•
•
Publication
21996748 | J:186130
First Author: Whipple CA
Year: 2012
Journal: Oncogene
Title: A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
Volume: 31
Issue: 20
Pages: 2535-44
•
•
•
•
•
Publication
31740923 | J:296248
First Author: Giopanou I
Year: 2020
Journal: Carcinogenesis
Title: Osteopontin drives KRAS-mutant lung adenocarcinoma.
Volume: 41
Issue: 8
Pages: 1134-1144
•
•
•
•
•
Publication
20080688 | J:156532
First Author: Hung KE
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Volume: 107
Issue: 4
Pages: 1565-70
•
•
•
•
•
Publication
22266220 | J:184949
First Author: O'Dell MR
Year: 2012
Journal: Cancer Res
Title: Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma.
Volume: 72
Issue: 6
Pages: 1557-67
•
•
•
•
•
Publication
20807812 | J:164210
First Author: Hill R
Year: 2010
Journal: Cancer Res
Title: PTEN loss accelerates KrasG12D-induced pancreatic cancer development.
Volume: 70
Issue: 18
Pages: 7114-24
•
•
•
•
•
Publication
19847165 | J:154041
First Author: Meylan E
Year: 2009
Journal: Nature
Title: Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma.
Volume: 462
Issue: 7269
Pages: 104-7
•
•
•
•
•
Publication
23285300 | J:195738
First Author: Lin C
Year: 2012
Journal: PLoS One
Title: Alveolar type II cells possess the capability of initiating lung tumor development.
Volume: 7
Issue: 12
Pages: e53817
•
•
•
•
•
Publication
21408169 | J:171709
First Author: Miller SJ
Year: 2011
Journal: PLoS One
Title: In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe.
Volume: 6
Issue: 3
Pages: e17384
•
•
•
•
•
Publication
30655555 | J:275289
First Author: Menon M
Year: 2019
Journal: Sci Rep
Title: A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors.
Volume: 9
Issue: 1
Pages: 201
•
•
•
•
•
Publication
31484658 | J:295220
First Author: Del Prete A
Year: 2019
Journal: Cancer Immunol Res
Title: The Atypical Receptor CCRL2 Is Essential for Lung Cancer Immune Surveillance.
Volume: 7
Issue: 11
Pages: 1775-1788
•
•
•
•
•
Publication
31036704 | J:285455
 
First Author: Wang X
Year: 2019
Journal: EMBO Mol Med
Title: Nf1 loss promotes Kras-driven lung adenocarcinoma and results in Psat1-mediated glutamate dependence.
Volume: 11
Issue: 6
•
•
•
•
•
Publication
18509000 | J:149009
First Author: Hammoud Z
Year: 2008
Journal: Endocr Relat Cancer
Title: Estrogen promotes tumor progression in a genetically defined mouse model of lung adenocarcinoma.
Volume: 15
Issue: 2
Pages: 475-83
•
•
•
•
•
Publication
24307564 | J:208063
First Author: Rodriguez E
Year: 2014
Journal: J Pathol
Title: Versatile and enhanced tumour modelling in mice via somatic cell transduction.
Volume: 232
Issue: 4
Pages: 449-57
•
•
•
•
•
Publication
28967920 | J:251982
First Author: Romero R
Year: 2017
Journal: Nat Med
Title: Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.
Volume: 23
Issue: 11
Pages: 1362-1368
•
•
•
•
•
Publication
27702896 | J:238629
First Author: McFadden DG
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma.
Volume: 113
Issue: 42
Pages: E6409-E6417
•
•
•
•
•
Publication
20595231 | J:161357
First Author: Zhao Z
Year: 2010
Journal: Genes Dev
Title: p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal.
Volume: 24
Issue: 13
Pages: 1389-402
•
•
•
•
•
Publication
30753336 | J:288706
     
First Author: Ochiai M
Year: 2019
Journal: Carcinogenesis
Title: Kras-driven heterotopic tumor development from hepatobiliary organoids.
•
•
•
•
•
Publication
30626590 | J:273222
First Author: Carrer A
Year: 2019
Journal: Cancer Discov
Title: Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis.
Volume: 9
Issue: 3
Pages: 416-435
•
•
•
•
•
Publication
33998997 | J:308273
   
First Author: Li S
Year: 2021
Journal: Elife
Title: Signaling levels mold the RAS mutation tropism of urethane.
Volume: 10
•
•
•
•
•
Publication
27338794 | J:235729
First Author: Manchado E
Year: 2016
Journal: Nature
Title: A combinatorial strategy for treating KRAS-mutant lung cancer.
Volume: 534
Issue: 7609
Pages: 647-51
•
•
•
•
•
Publication
30956771 | J:298276
First Author: Khatri A
Year: 2019
Journal: Oncotarget
Title: ABL kinase inhibition sensitizes primary lung adenocarcinomas to chemotherapy by promoting tumor cell differentiation.
Volume: 10
Issue: 20
Pages: 1874-1886
•
•
•
•
•
Publication
23891977 | J:310917
First Author: Greer RL
Year: 2013
Journal: Gastroenterology
Title: Numb regulates acinar cell dedifferentiation and survival during pancreatic damage and acinar-to-ductal metaplasia.
Volume: 145
Issue: 5
Pages: 1088-1097.e8
•
•
•
•
•
Publication
37310065 | J:359038
First Author: Namikawa M
Year: 2023
Journal: J Pathol
Title: Simultaneous activation of Kras-Akt and Notch pathways induces extrahepatic biliary cancer via the mTORC1 pathway.
Volume: 260
Issue: 4
Pages: 478-492
•
•
•
•
•
Publication
32221533 | J:299115
First Author: Böttinger P
Year: 2020
Journal: Carcinogenesis
Title: Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens.
Volume: 41
Issue: 11
Pages: 1605-1615
•
•
•
•
•
Publication
23744837 | J:199569
First Author: Janzen DM
Year: 2013
Journal: Cancer Res
Title: Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy.
Volume: 73
Issue: 15
Pages: 4697-710
•
•
•
•
•
Publication
25801914 | J:224952
First Author: Chang YI
Year: 2015
Journal: Leukemia
Title: Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.
Volume: 29
Issue: 9
Pages: 1847-56
•
•
•
•
•
Publication
24569456 | J:209632
First Author: Gritsman K
Year: 2014
Journal: J Clin Invest
Title: Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α.
Volume: 124
Issue: 4
Pages: 1794-809
•
•
•
•
•
Publication
18356293 | J:133578
First Author: Podsypanina K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras.
Volume: 105
Issue: 13
Pages: 5242-7
•
•
•
•
•
Publication
24114272 | J:201963
First Author: Song Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Evolutionary etiology of high-grade astrocytomas.
Volume: 110
Issue: 44
Pages: 17933-8
•
•
•
•
•
Publication
34249932 | J:308024
 
First Author: Urrutia G
Year: 2021
Journal: Front Cell Dev Biol
Title: Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks.
Volume: 9
Pages: 681153
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom