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Search results 401 to 500 out of 645 for Lefty1

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:1289467
Assay Type: RNA in situ
Annotation Date: 2013-02-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619112
Stage: TS12
Assay Id: MGI:5463912
Age: embryonic day 8.0
Image: 3j (top right)
Specimen Label: 3j (top right)
Detected: false
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:3655502
Assay Type: RNA in situ
Annotation Date: 2006-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160517
Pattern: Non-Uniform
Stage: TS07
Assay Id: MGI:3655507
Age: embryonic day 5.5
Note: Expression is detected on one side of the primitive endoderm.
Specimen Label: E5.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3655502
Assay Type: RNA in situ
Annotation Date: 2006-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160516
Pattern: Non-Uniform
Stage: TS06
Assay Id: MGI:3655507
Age: embryonic day 4.25
Note: Expression is detected on one side (the upper side) of the primitive endoderm.
Specimen Label: E4.25
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5489775
Assay Type: RNA in situ
Annotation Date: 2013-06-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:5489804
Age: embryonic day 6.5
Image: 5H
Note: Expression was detected in the distal visceral endoderm in the mutant embryos.
Specimen Label: 5H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1278390
Assay Type: RNA in situ
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:5688691
Age: embryonic day 6.5
Image: 7F
Specimen Label: 7F
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1278390
Assay Type: RNA in situ
Annotation Date: 2015-10-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160518
Stage: TS08
Assay Id: MGI:5688691
Age: embryonic day 6.5
Image: 7G
Note: Expression was absent in 5 of 7 mutants.
Specimen Label: 7G
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1278390
Assay Type: RNA in situ
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:5688691
Age: embryonic day 6.5
Image: 7H
Note: Expression was detected in all the mutant embryos, but 4 of 11 revealed spotted disorganization.
Specimen Label: 7H
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1278390
Assay Type: RNA in situ
Annotation Date: 2015-10-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160518
Stage: TS08
Assay Id: MGI:5688691
Age: embryonic day 6.5
Image: 7I
Note: Expression was absent in 6 out of 11 mutants.
Specimen Label: 7I
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:1278390
Assay Type: RNA in situ
Annotation Date: 2015-10-01
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:5688691
Age: embryonic day 6.5
Image: 7J
Note: Expression was decreased in 5 out of 11 mutants.
Specimen Label: 7J
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:1278390
Assay Type: RNA in situ
Annotation Date: 2015-10-01
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:5688691
Age: embryonic day 6.5
Note: Expression was detected at a low level in only 2 of 7 mutants.
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1278390
Assay Type: RNA in situ
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160518
Pattern: Not Specified
Stage: TS08
Assay Id: MGI:5688691
Age: embryonic day 6.5
Note: All of the Otx2 mutant embryos showed normal expression.
Specimen Label: not shown
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:5810354
Assay Type: RNA in situ
Annotation Date: 2016-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160517
Pattern: Not Specified
Stage: TS07
Assay Id: MGI:5810385
Age: embryonic day 5.5
Image: 4d E5.5 WT
Specimen Label: 4d E5.5 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5810354
Assay Type: RNA in situ
Annotation Date: 2016-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160516
Pattern: Not Specified
Stage: TS06
Assay Id: MGI:5810385
Age: embryonic day 4.5
Image: 4d E4.5 WT
Specimen Label: 4d E4.5 WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5810354
Assay Type: RNA in situ
Annotation Date: 2016-11-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160517
Stage: TS07
Assay Id: MGI:5810385
Age: embryonic day 5.5
Image: 4d E5.5 KO
Specimen Label: 4d E5.5 KO
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5810354
Assay Type: RNA in situ
Annotation Date: 2016-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160516
Pattern: Not Specified
Stage: TS06
Assay Id: MGI:5810385
Age: embryonic day 4.5
Image: 4d E4.5 KO
Note: Equivalent expression as in the wild-type.
Specimen Label: 4d E4.5 KO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6315344
Assay Type: RNA in situ
Annotation Date: 2019-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160519
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:6315363
Age: embryonic day 6.5
Image: 3B
Note: Expression in distal visceral endoderm.
Specimen Label: 3B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1206113
Assay Type: RNA in situ
Annotation Date: 2013-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3187621
Stage: TS21
Assay Id: MGI:5520192
Age: embryonic day 13.5
Specimen Label: Table 1 13.5
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1206113
Assay Type: RNA in situ
Annotation Date: 2013-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3187625
Stage: TS25
Assay Id: MGI:5520192
Age: embryonic day 17.5
Specimen Label: Table 1 17.5
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:1278390
Assay Type: RNA in situ
Annotation Date: 2022-10-19
Strength: Present
Sex: Male
Emaps: EMAPS:381339
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:7356407
Age: embryonic day 6.5
Image: 9Aa'
Note: Expressing cells ectopically accumulated distally.
Specimen Label: 9Aa'
Detected: true
Specimen Num: 2
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Publication
25722189 | J:221138
First Author: Lee MS
Year: 2015
Journal: Dev Biol
Title: IFT46 plays an essential role in cilia development.
Volume: 400
Issue: 2
Pages: 248-57
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Publication
27655833 | J:238128
First Author: Shen Z
Year: 2016
Journal: Carcinogenesis
Title: Novel Helicobacter species H.japonicum isolated from laboratory mice from Japan induces typhlocolitis and lower bowel carcinoma in C57BL/129 IL10-/- mice.
Volume: 37
Issue: 12
Pages: 1190-1198
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Publication
15062104 | J:90108
First Author: Chen C
Year: 2004
Journal: Curr Biol
Title: Two modes by which Lefty proteins inhibit nodal signaling.
Volume: 14
Issue: 7
Pages: 618-24
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Publication
18393305 | J:134312
First Author: Zhang YQ
Year: 2008
Journal: Dev Dyn
Title: Nodal and lefty signaling regulates the growth of pancreatic cells.
Volume: 237
Issue: 5
Pages: 1255-67
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Publication
8610011 | J:32932
First Author: Meno C
Year: 1996
Journal: Nature
Title: Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos.
Volume: 381
Issue: 6578
Pages: 151-5
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Publication
9708732 | J:49484
First Author: Yoshioka H
Year: 1998
Journal: Cell
Title: Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry.
Volume: 94
Issue: 3
Pages: 299-305
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Publication
17011489 | J:119676
First Author: Nakamura T
Year: 2006
Journal: Dev Cell
Title: Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system.
Volume: 11
Issue: 4
Pages: 495-504
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Publication
9376323 | J:42770
First Author: Heymer J
Year: 1997
Journal: Mech Dev
Title: The expression pattern of nodal and lefty in the mouse mutant Ft suggests a function in the establishment of handedness.
Volume: 66
Issue: 1-2
Pages: 5-11
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Publication
23544137 | J:199895
First Author: Inácio JM
Year: 2013
Journal: PLoS One
Title: The dynamic right-to-left translocation of Cerl2 is involved in the regulation and termination of Nodal activity in the mouse node.
Volume: 8
Issue: 3
Pages: e60406
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Publication
11448943 | J:70583
First Author: Cummings CJ
Year: 2001
Journal: Hum Mol Genet
Title: Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.
Volume: 10
Issue: 14
Pages: 1511-8
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Publication
9889116 | J:52052
First Author: King T
Year: 1999
Journal: Curr Biol
Title: Embryonic asymmetry: the left side gets all the best genes.
Volume: 9
Issue: 1
Pages: R18-22
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Publication
17662710 | J:124666
First Author: Torres-Padilla ME
Year: 2007
Journal: Dev Biol
Title: The anterior visceral endoderm of the mouse embryo is established from both preimplantation precursor cells and by de novo gene expression after implantation.
Volume: 309
Issue: 1
Pages: 97-112
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Publication
31240264 | J:278278
 
First Author: Sasaki K
Year: 2019
Journal: Commun Biol
Title: Calaxin is required for cilia-driven determination of vertebrate laterality.
Volume: 2
Pages: 226
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Publication
9708731 | J:49052
First Author: Meno C
Year: 1998
Journal: Cell
Title: lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal.
Volume: 94
Issue: 3
Pages: 287-97
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Publication
17075880 | J:116645
First Author: Cota CD
Year: 2006
Journal: Dev Dyn
Title: Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis.
Volume: 235
Issue: 12
Pages: 3438-47
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Publication
9348041 | J:49270
First Author: Meno C
Year: 1997
Journal: Genes Cells
Title: Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos.
Volume: 2
Issue: 8
Pages: 513-24
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Publication
10349618 | J:52218
First Author: King T
Year: 1998
Journal: Mech Dev
Title: The role of the brachyury gene in heart development and left-right specification in the mouse.
Volume: 79
Issue: 1-2
Pages: 29-37
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Publication
26348837 | J:228916
First Author: Kluth O
Year: 2015
Journal: PLoS Genet
Title: Identification of Four Mouse Diabetes Candidate Genes Altering β-Cell Proliferation.
Volume: 11
Issue: 9
Pages: e1005506
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Publication
10385627 | J:56146
First Author: Adachi H
Year: 1999
Journal: Genes Dev
Title: Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer.
Volume: 13
Issue: 12
Pages: 1589-600
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Publication
21364967 | J:170681
First Author: Trichas G
Year: 2011
Journal: PLoS Biol
Title: Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm.
Volume: 9
Issue: 2
Pages: e1001019
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Publication
9990851 | J:53088
First Author: Saijoh Y
Year: 1999
Journal: Genes Dev
Title: Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of lefty-1 and lefty-2.
Volume: 13
Issue: 3
Pages: 259-69
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Publication
15466485 | J:93051
First Author: Marques S
Year: 2004
Journal: Genes Dev
Title: The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis.
Volume: 18
Issue: 19
Pages: 2342-7
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Publication
15121860 | J:89880
First Author: Bonnafe E
Year: 2004
Journal: Mol Cell Biol
Title: The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification.
Volume: 24
Issue: 10
Pages: 4417-27
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Publication
7649373 | J:28316
First Author: Bouillet P
Year: 1995
Journal: Dev Biol
Title: Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2).
Volume: 170
Issue: 2
Pages: 420-33
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Publication
14657239 | J:90046
First Author: Di Stefano P
Year: 2004
Journal: Mol Biol Cell
Title: P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading.
Volume: 15
Issue: 2
Pages: 787-800
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Publication
10727869 | J:61450
First Author: Sapin V
Year: 2000
Journal: Mech Dev
Title: Differential expression of retinoic acid-inducible (Stra) genes during mouse placentation.
Volume: 92
Issue: 2
Pages: 295-9
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Publication
15736223 | J:97079
First Author: Saijoh Y
Year: 2005
Journal: Dev Dyn
Title: Two nodal-responsive enhancers control left-right asymmetric expression of Nodal.
Volume: 232
Issue: 4
Pages: 1031-6
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Publication
10603343 | J:56972
First Author: Constam DB
Year: 2000
Journal: Development
Title: Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping.
Volume: 127
Issue: 2
Pages: 245-54
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Publication
10677256 | J:60975
First Author: Chang H
Year: 2000
Journal: Dev Biol
Title: Smad5 is essential for left-right asymmetry in mice.
Volume: 219
Issue: 1
Pages: 71-8
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Publication
10500184 | J:57950
First Author: Tsukui T
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1.
Volume: 96
Issue: 20
Pages: 11376-81
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Publication
18773491 | J:142430
First Author: Kumar A
Year: 2008
Journal: Dev Dyn
Title: Broad mesodermal and endodermal deletion of Nodal at postgastrulation stages results solely in left/right axial defects.
Volume: 237
Issue: 12
Pages: 3591-601
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Publication
32579954 | J:293791
First Author: Ngo J
Year: 2020
Journal: Dev Biol
Title: Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation.
Volume: 464
Issue: 2
Pages: 161-175
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Publication
11703930 | J:70483
First Author: Meno C
Year: 2001
Journal: Dev Cell
Title: Diffusion of nodal signaling activity in the absence of the feedback inhibitor Lefty2.
Volume: 1
Issue: 1
Pages: 127-38
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Publication
15504371 | J:113766
First Author: Zhang M
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Foxj1 regulates asymmetric gene expression during left-right axis patterning in mice.
Volume: 324
Issue: 4
Pages: 1413-20
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Publication
10700179 | J:60755
First Author: Rankin CT
Year: 2000
Journal: Nat Genet
Title: Regulation of left-right patterning in mice by growth/differentiation factor-1.
Volume: 24
Issue: 3
Pages: 262-5
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Publication
21802298 | J:175616
First Author: Clements M
Year: 2011
Journal: Curr Biol
Title: Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification.
Volume: 21
Issue: 15
Pages: 1289-95
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Publication
9825674 | J:51210
First Author: Ramsdell AF
Year: 1998
Journal: Trends Genet
Title: Molecular mechanisms of vertebrate left-right development.
Volume: 14
Issue: 11
Pages: 459-65
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Publication
27305836 | J:252050
 
First Author: Sung YH
Year: 2016
Journal: Sci Rep
Title: PIERCE1 is critical for specification of left-right asymmetry in mice.
Volume: 6
Pages: 27932
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Publication
15371312 | J:93573
First Author: Rana AA
Year: 2004
Journal: Development
Title: Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates.
Volume: 131
Issue: 20
Pages: 4999-5007
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Publication
12062060 | J:77401
First Author: Pennekamp P
Year: 2002
Journal: Curr Biol
Title: The ion channel polycystin-2 is required for left-right axis determination in mice.
Volume: 12
Issue: 11
Pages: 938-43
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Publication
21307093 | J:170490
First Author: Field S
Year: 2011
Journal: Development
Title: Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2.
Volume: 138
Issue: 6
Pages: 1131-42
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Publication
19666828 | J:152173
First Author: Maisonneuve C
Year: 2009
Journal: Development
Title: Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow.
Volume: 136
Issue: 17
Pages: 3019-30
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Publication
33199844 | J:306151
First Author: Nguyen DH
Year: 2020
Journal: Nat Cell Biol
Title: Apoptosis in the fetal testis eliminates developmentally defective germ cell clones.
Volume: 22
Issue: 12
Pages: 1423-1435
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Publication
12730123 | J:83387
First Author: Raya A
Year: 2003
Journal: Genes Dev
Title: Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos.
Volume: 17
Issue: 10
Pages: 1213-8
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Publication
9598342 | J:47841
 
First Author: Varlet I
Year: 1997
Journal: Cold Spring Harb Symp Quant Biol
Title: Nodal signaling and axis formation in the mouse.
Volume: 62
Pages: 105-13
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Publication
12730124 | J:83358
First Author: Krebs LT
Year: 2003
Journal: Genes Dev
Title: Notch signaling regulates left-right asymmetry determination by inducing Nodal expression.
Volume: 17
Issue: 10
Pages: 1207-12
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Publication
9466889 | J:45709
First Author: Melloy PG
Year: 1998
Journal: Dev Biol
Title: No turning, a mouse mutation causing left-right and axial patterning defects.
Volume: 193
Issue: 1
Pages: 77-89
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Publication
12231623 | J:79098
First Author: Brennan J
Year: 2002
Journal: Genes Dev
Title: Nodal activity in the node governs left-right asymmetry.
Volume: 16
Issue: 18
Pages: 2339-44
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Publication
18854136 | J:143286
First Author: Kwon GS
Year: 2008
Journal: Dev Cell
Title: The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages.
Volume: 15
Issue: 4
Pages: 509-20
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Publication
22990867 | J:187732
 
First Author: Kawamura N
Year: 2012
Journal: Nat Commun
Title: Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos.
Volume: 3
Pages: 1071
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Publication
12654299 | J:82703
First Author: Saijoh Y
Year: 2003
Journal: Dev Biol
Title: Left-right patterning of the mouse lateral plate requires nodal produced in the node.
Volume: 256
Issue: 1
Pages: 160-72
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Publication
23221368 | J:191052
First Author: Wu Q
Year: 2013
Journal: Development
Title: Nodal/activin signaling promotes male germ cell fate and suppresses female programming in somatic cells.
Volume: 140
Issue: 2
Pages: 291-300
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Publication
17913787 | J:126337
First Author: Oki S
Year: 2007
Journal: Development
Title: Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo.
Volume: 134
Issue: 21
Pages: 3893-904
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Publication
10985852 | J:64866
First Author: Kimura C
Year: 2000
Journal: Dev Biol
Title: Visceral endoderm mediates forebrain development by suppressing posteriorizing signals.
Volume: 225
Issue: 2
Pages: 304-21
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Publication
10545241 | J:58413
First Author: Wasiak S
Year: 1999
Journal: Dev Biol
Title: Retinoic acid affects left-right patterning.
Volume: 215
Issue: 2
Pages: 332-42
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Publication
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