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Search results 401 to 500 out of 1374 for Lox

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Allele
Pip5k1c<tm2Csab> | MGI:5496877
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma; targeted mutation 2, Charles Abrams
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tuba8<tm1.2Ctpd> | MGI:6094271
Name: tubulin, alpha 8; targeted mutation 1.2, Christine P Diggle
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Pten<tm1Jcad> | MGI:6159663
Name: phosphatase and tensin homolog; targeted mutation 1, Juan Cadinanos
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Pten<tm1.1Jcad> | MGI:6159664
Name: phosphatase and tensin homolog; targeted mutation 1.1, Juan Cadinanos
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Gpr15<em2J> | MGI:6506232
Name: G protein-coupled receptor 15; endonuclease-mediated mutation 2, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Reporter
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Allele
Rxfp3<em2J> | MGI:6506220
Name: relaxin family peptide receptor 3; endonuclease-mediated mutation 2, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Reporter
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Allele
Cldn13<em2J> | MGI:6506234
Name: claudin 13; endonuclease-mediated mutation 2, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Reporter
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Allele
Gcgr<tm1.2Rdi> | MGI:6492461
Name: glucagon receptor; targeted mutation 1.2, Richard DiMarchi
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Pomc<tm2.1Lowl> | MGI:6718624
Name: pro-opiomelanocortin-alpha; targeted mutation 2.1, Bradford B Lowell
Allele Type: Targeted
Attribute String: Conditional ready
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Strain
MGI:7382783 | B6.Cg-H2-K1<b-em1Tyj>/AjgrJ
Attribute String: congenic, endonuclease-mediated mutation, mutant strain
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Allele
Inpp4a<tm2.1Tsak> | MGI:7520501
Name: inositol polyphosphate-4-phosphatase, type I; targeted mutation 2.1, Takehiko Sasaki
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Inpp4a<tm2.2Tsak> | MGI:7520502
Name: inositol polyphosphate-4-phosphatase, type I; targeted mutation 2.2, Takehiko Sasaki
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tmem117<tm1.1Thor> | MGI:7616761
Name: transmembrane protein 117; targeted mutation 1.1, Bernard Thorens
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
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Genotype
Genotype
Symbol: C5ar1/C5ar1
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Npy1r/Npy1r
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: C5ar1/C5ar1
Background: B6.Cg-C5ar1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aplnr/Aplnr<+>
Background: C57BL/6-Aplnr
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aplnr/Aplnr
Background: C57BL/6-Aplnr
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sparc/Sparc
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tspyl2/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aplnr/Aplnr
Background: involves: C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Publication
18949503 | -
First Author: Bannenberg G
Year: 2009
Journal: Lipids
Title: Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana.
Volume: 44
Issue: 2
Pages: 85-95
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HT Experiment
E-GEOD-44110 | Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice
Series Id: GSE44110
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE256400 | The Ciliary GTPase ARL13B maintains Ductule Physiology through the Primary and Motile Cilia in Male Reproduction
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
20534727 | J:163027
First Author: Canalis E
Year: 2010
Journal: Endocrinology
Title: Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice.
Volume: 151
Issue: 8
Pages: 3490-501
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Publication
12226483 | -
First Author: Porta H
Year: 2002
Journal: Plant Physiol
Title: Plant lipoxygenases. Physiological and molecular features.
Volume: 130
Issue: 1
Pages: 15-21
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Publication
12221977 | -
 
First Author: Feussner I
Year: 2002
Journal: Annu Rev Plant Biol
Title: The lipoxygenase pathway.
Volume: 53
Pages: 275-97
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Publication
12432926 | -
 
First Author: Oliw EH
Year: 2002
Journal: Prostaglandins Other Lipid Mediat
Title: Plant and fungal lipoxygenases.
Volume: 68-69
Pages: 313-23
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Protein Domain
IPR042057 | Lipoxy_PLAT/LH2
Type: Domain
Description: This is the PLAT/LH2 domain of plant lipoxygenase related proteins. Lipoxygenases are nonheme, nonsulfur iron dioxygenases that act on lipid substrates containing one or more (Z,Z)-1,4-pentadiene moieties. In plants, the immediate products are involved in defense mechanisms against pathogens and may be precursors of metabolic regulators [, , ]. The generally proposed function of PLAT/LH2 domains is to mediate interaction with lipids or membrane bound proteins [].Lipoxygenases can be classified as 9- and 13-lipoxygenases, according to the position of oxygen incorporation in linoleic acid and linolenic acid, the most important substrates for LOX catalysis in plants. There are six A. thaliana lipoxygenases identified: AtLOX1-6, among which AtLOX-1 and AtLOX-5 are 9S-lipoxygenases, and AtLOX-2, AtLOX-3, AtLOX-4 and AtLOX-6 are 13S-lipoxygenases [].
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Publication
9820538 | J:115035
First Author: Andersson A
Year: 1998
Journal: J Immunol
Title: Early IFN-gamma production and innate immunity during Listeria monocytogenes infection in the absence of NK cells.
Volume: 161
Issue: 10
Pages: 5600-6
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Strain
MGI:2164732 | STOCK Il2rg<tm1Cgn>/J
Attribute String: mutant stock, targeted mutation
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Publication
22957096 | J:191642
First Author: Greenblatt MB
Year: 2012
Journal: PLoS One
Title: Graft versus host disease in the bone marrow, liver and thymus humanized mouse model.
Volume: 7
Issue: 9
Pages: e44664
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Publication
18974303 | J:143923
First Author: von Köckritz-Blickwede M
Year: 2008
Journal: Am J Pathol
Title: Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model.
Volume: 173
Issue: 6
Pages: 1657-68
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Publication
23287858 | J:194772
First Author: García-Ojeda ME
Year: 2013
Journal: Blood
Title: GATA-3 promotes T-cell specification by repressing B-cell potential in pro-T cells in mice.
Volume: 121
Issue: 10
Pages: 1749-59
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Strain
MGI:4437261 | B6;FVB-Tg(GFP/KRAS2/ALPP)1Brn/Cnrm
Attribute String: transgenic, mutant stock
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Publication
11641780 | J:72206
First Author: Meuwissen R
Year: 2001
Journal: Oncogene
Title: Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene.
Volume: 20
Issue: 45
Pages: 6551-8
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Strain
MGI:4821472 | B6.129S6-Neurog3<tm1(EGFP)Khk>/Mmucd
Attribute String: targeted mutation, mutant strain, congenic
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Publication
12080087 | J:77398
First Author: Lee CS
Year: 2002
Journal: Genes Dev
Title: Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity.
Volume: 16
Issue: 12
Pages: 1488-97
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Publication
30661759 | J:338071
First Author: Sharon N
Year: 2019
Journal: Cell
Title: A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets.
Volume: 176
Issue: 4
Pages: 790-804.e13
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Publication
19563657 | J:152852
 
First Author: Zheng K
Year: 2009
Journal: BMC Dev Biol
Title: The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse.
Volume: 9
Pages: 38
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Publication
18071024 | J:132455
First Author: White P
Year: 2008
Journal: Diabetes
Title: Defining pancreatic endocrine precursors and their descendants.
Volume: 57
Issue: 3
Pages: 654-68
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Allele
Fgf8<tm3Mrc> | MGI:2686826
Name: fibroblast growth factor 8; targeted mutation 3, Mario R Capecchi
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph, Reporter
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Publication
31298935 | J:290942
First Author: Nabizadeh JA
Year: 2019
Journal: FASEB J
Title: C5a receptors C5aR1 and C5aR2 mediate opposing pathologies in a mouse model of melanoma.
Volume: 33
Issue: 10
Pages: 11060-11071
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Allele
Kit<tm3.1Bsm> | MGI:3044953
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 3.1, Peter Besmer
Allele Type: Targeted
Attribute String: Hypomorph
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Strain
MGI:6802118 | STOCK Prkar1a<tm1.2Lsk>/J
Attribute String: targeted mutation, mutant stock
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Publication
37577930 | J:340497
 
First Author: Wang W
Year: 2023
Journal: Dis Model Mech
Title: Disrupting Hedgehog signaling in melanocytes by SUFU knockout leads to ocular melanocytosis and anterior segment malformation.
Volume: 16
Issue: 8
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Publication
26988598 | J:259565
 
First Author: Saito K
Year: 2016
Journal: Sci Rep
Title: PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice.
Volume: 6
Pages: 23459
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Allele
Akr1b7<tm1.1Fth> | MGI:3629297
Name: aldo-keto reductase family 1, member B7; targeted mutation 1.1, Franz Theuring
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
30177795 | J:267039
First Author: Menegas W
Year: 2018
Journal: Nat Neurosci
Title: Dopamine neurons projecting to the posterior striatum reinforce avoidance of threatening stimuli.
Volume: 21
Issue: 10
Pages: 1421-1430
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Strain
MGI:3699940 | B6.129-St6gal1<tm2Jxm>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3699942 | B6.129-St6gal1<tm2Jxm>
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Tamalin<tm1.1Nak> | MGI:3723519
Name: trafficking regulator and scaffold protein tamalin; targeted mutation 1.1, Shigetada Nakanishi
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3758633 | B6.129S-Tamalin<tm1.1Nak>
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Tamalin<tm2.1Nak> | MGI:3757981
Name: trafficking regulator and scaffold protein tamalin; targeted mutation 2.1, Shigetada Nakanishi
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3758634 | B6.Cg-Tamalin<tm2.1Nak>
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:6145202 | B6.Cg-Tamalin<tm2.1Nak>/SiaRbrc
Attribute String: mutant strain, congenic, targeted mutation
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Publication
20689039 | J:163696
First Author: Sun Z
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Adult testicular dysgenesis of Inhba conditional knockout mice may also be caused by disruption of cross-talk between Leydig cells and germ cells.
Volume: 107
Issue: 35
Pages: E135; author reply E136
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Allele
Pyy<tm1.1Batt> | MGI:3771165
Name: peptide YY; targeted mutation 1.1, Rachel L Batterham
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
29117554 | J:255219
First Author: Rai R
Year: 2017
Journal: Cell Rep
Title: Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan.
Volume: 21
Issue: 6
Pages: 1471-1480
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Allele
Cyp11a1<tm2Bcc> | MGI:3778793
 
Name: cytochrome P450, family 11, subfamily a, polypeptide 1; targeted mutation 2, Bon-Chu Chung
Allele Type: Targeted
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Allele
Ccn2<tm1.1Vlcg> | MGI:4822056
Name: cellular communication network factor 2; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Dll4<tm2.1Vlcg> | MGI:5302387
Name: delta like canonical Notch ligand 4; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Gt(ROSA)26Sor<tm10(ACTB-tdTomato)Luo> | MGI:5314256
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 10, Liqun Luo
Allele Type: Targeted
Attribute String: Reporter
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Publication
23754961 | J:199075
First Author: Carofiglio F
Year: 2013
Journal: PLoS Genet
Title: SPO11-independent DNA repair foci and their role in meiotic silencing.
Volume: 9
Issue: 6
Pages: e1003538
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Allele
Etl4<tm1(cre)Kymm> | MGI:5435947
Name: enhancer trap locus 4; targeted mutation 1, Ken-ichi Yamamura
Allele Type: Targeted
Attribute String: Recombinase, RMCE-ready
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Publication
26794869 | J:240799
First Author: Yim HC
Year: 2016
Journal: Cell Res
Title: The kinase activity of PKR represses inflammasome activity.
Volume: 26
Issue: 3
Pages: 367-79
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Allele
Ghrl<tm1Suss> | MGI:5485212
Name: ghrelin; targeted mutation 1, Lori Sussel
Allele Type: Targeted
Attribute String: Null/knockout, RMCE-ready
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Allele
Gt(ROSA)26Sor<tm2.1Vlcg> | MGI:5546020
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Reporter
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Allele
Tgfbr1<tm1.1Vlcg> | MGI:5544796
Name: transforming growth factor, beta receptor I; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tie1<tm1.1Vlcg> | MGI:5544797
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Flt1<tm1.1Vlcg> | MGI:5544799
Name: FMS-like tyrosine kinase 1; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Kdr<tm1.1Vlcg> | MGI:5544800
Name: kinase insert domain protein receptor; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Dll4<tm3.1Vlcg> | MGI:5545924
Name: delta like canonical Notch ligand 4; targeted mutation 3.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change, Reporter
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Allele
Acvr1b<tm2.1Vlcg> | MGI:5544768
Name: activin A receptor, type 1B; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Chrd<tm2.1Vlcg> | MGI:5544769
Name: chordin; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Dicer1<tm2.1Vlcg> | MGI:5544770
Name: dicer 1, ribonuclease type III; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Dkk4<tm2.1Vlcg> | MGI:5544771
Name: dickkopf WNT signaling pathway inhibitor 4; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Exosc3<tm2.1Vlcg> | MGI:5544772
Name: exosome component 3; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Exosc10<tm1.1Vlcg> | MGI:5544774
Name: exosome component 10; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Gdf11<tm1.1Vlcg> | MGI:5544775
Name: growth differentiation factor 11; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Adgra2<tm2.1Vlcg> | MGI:5544776
Name: adhesion G protein-coupled receptor A2; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Gt(ROSA)26Sor<tm2Vlcg> | MGI:5544780
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Hprt1<tm1.1Vlcg> | MGI:5544781
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Il2rg<tm1.1Vlcg> | MGI:5544782
Name: interleukin 2 receptor, gamma chain; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Il2rg<tm2.1Vlcg> | MGI:5544783
Name: interleukin 2 receptor, gamma chain; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Mstn<tm1.1Vlcg> | MGI:5544784
Name: myostatin; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph
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Allele
Plxnd1<tm1.1Vlcg> | MGI:5544786
Name: plexin D1; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Ret<tm1.1Vlcg> | MGI:5544788
Name: ret proto-oncogene; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Drosha<tm1.1Vlcg> | MGI:5544789
Name: drosha, ribonuclease type III; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Drosha<tm2.1Vlcg> | MGI:5544790
Name: drosha, ribonuclease type III; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Scn9a<tm1.1Vlcg> | MGI:5544791
Name: sodium channel, voltage-gated, type IX, alpha; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Sirt1<tm1.1Vlcg> | MGI:5544792
Name: sirtuin 1; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Sost<tm2.1Vlcg> | MGI:5544793
Name: sclerostin; targeted mutation 2.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Sox10<tm1.1Sout> | MGI:5544794
Name: SRY (sex determining region Y)-box 10; targeted mutation 1.1, E Southard-Smith
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tek<tm1.1Vlcg> | MGI:5544795
Name: TEK receptor tyrosine kinase; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Exosc3<tm1.1Uba> | MGI:5702728
Name: exosome component 3; targeted mutation 1.1, Uttiya Basu
Allele Type: Targeted
Attribute String: Conditional ready, No functional change, Reporter
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Allele
Shank3<tm1Cmpl> | MGI:5788281
Name: SH3 and multiple ankyrin repeat domains 3; targeted mutation 1, Craig M Powell
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Trp53<tm1.1Dmfe> | MGI:5907990
Name: transformation related protein 53; targeted mutation 1.1, David M Feldser
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
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Allele
Rb1<tm1.1Dmfe> | MGI:5907993
Name: RB transcriptional corepressor 1; targeted mutation 1.1, David M Feldser
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
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Allele
Notch2<tm2.2Ecan> | MGI:6157623
Name: notch 2; targeted mutation 2.2, Ernesto Canalis
Allele Type: Targeted
Attribute String: Reporter
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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