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Search results 401 to 500 out of 545 for Map2k1

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Type Details Score
Publication
9852579 | J:68953
First Author: Klesse LJ
Year: 1998
Journal: J Neurosci
Title: p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons.
Volume: 18
Issue: 24
Pages: 10420-8
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Publication
26435415 | J:227204
First Author: Li A
Year: 2015
Journal: Am J Pathol
Title: Human polycystin-2 transgene dose-dependently rescues ADPKD phenotypes in Pkd2 mutant mice.
Volume: 185
Issue: 10
Pages: 2843-60
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Publication
34010630 | J:321004
First Author: Jiang M
Year: 2021
Journal: Dev Cell
Title: VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway.
Volume: 56
Issue: 11
Pages: 1646-1660.e5
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Publication
25359213 | J:223433
First Author: Hernández-Porras I
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: K-RasV14I recapitulates Noonan syndrome in mice.
Volume: 111
Issue: 46
Pages: 16395-400
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Publication
36111785 | J:329259
   
First Author: Tomita H
Year: 2022
Journal: Elife
Title: 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome.
Volume: 11
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Publication
12663500 | J:82839
First Author: Popova NV
Year: 2003
Journal: Carcinogenesis
Title: Identification of two keratinocyte stem cell regulatory loci implicated in skin carcinogenesis.
Volume: 24
Issue: 3
Pages: 417-25
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Publication
14594209 | J:86336
 
First Author: Popova NV
Year: 2004
Journal: Curr Top Microbiol Immunol
Title: Genetic regulation of mouse stem cells: identification of two keratinocyte stem cell regulatory loci.
Volume: 280
Pages: 111-37
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Publication
18619436 | J:138857
First Author: Hislop NR
Year: 2008
Journal: Dev Biol
Title: Grhl3 and Lmo4 play coordinate roles in epidermal migration.
Volume: 321
Issue: 1
Pages: 263-72
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Publication
27693558 | J:237841
First Author: Xu P
Year: 2016
Journal: Cancer Lett
Title: Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.
Volume: 383
Issue: 2
Pages: 161-170
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Publication
17707671 | J:127326
First Author: Elsaid AF
Year: 2007
Journal: Mol Genet Metab
Title: Differential perturbation of the Fgf/Erk1/2 and Shh pathways in the C57BL/6N and SWV embryonic limb buds after mid-gestational cadmium chloride administration.
Volume: 92
Issue: 3
Pages: 258-70
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Publication
19734904 | J:152783
First Author: Mandal M
Year: 2009
Journal: Nat Immunol
Title: Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development.
Volume: 10
Issue: 10
Pages: 1110-7
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Publication
22919064 | J:192943
First Author: Cuffe JS
Year: 2012
Journal: Endocrinology
Title: Maternal corticosterone exposure in the mouse has sex-specific effects on placental growth and mRNA expression.
Volume: 153
Issue: 11
Pages: 5500-11
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Publication
23469020 | J:199499
First Author: Gerhardt C
Year: 2013
Journal: PLoS One
Title: The ciliary protein Ftm is required for ventricular wall and septal development.
Volume: 8
Issue: 2
Pages: e57545
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Publication
30592646 | J:288966
First Author: Chang S
Year: 2019
Journal: FASEB J
Title: The effect of folic acid deficiency on FGF pathway via Brachyury regulation in neural tube defects.
Volume: 33
Issue: 4
Pages: 4688-4702
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Publication
31424120 | J:282259
First Author: Gal H
Year: 2019
Journal: EMBO J
Title: Molecular pathways of senescence regulate placental structure and function.
Volume: 38
Issue: 18
Pages: e100849
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Publication
11435472 | J:71331
First Author: Ingram DA
Year: 2001
Journal: J Exp Med
Title: Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro.
Volume: 194
Issue: 1
Pages: 57-69
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Publication
10704452 | J:75421
First Author: Garratt AN
Year: 2000
Journal: J Cell Biol
Title: A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool.
Volume: 148
Issue: 5
Pages: 1035-46
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Publication
20884876 | J:182094
First Author: Huang ZP
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects.
Volume: 30
Issue: 12
Pages: 2575-86
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Publication
18760695 | J:145464
First Author: Brinkmann BG
Year: 2008
Journal: Neuron
Title: Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
Volume: 59
Issue: 4
Pages: 581-95
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Publication
20530870 | J:163721
First Author: Yang T
Year: 2010
Journal: J Clin Invest
Title: E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta.
Volume: 120
Issue: 7
Pages: 2474-85
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Publication
18483625 | J:137729
First Author: Schuhmacher AJ
Year: 2008
Journal: J Clin Invest
Title: A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition.
Volume: 118
Issue: 6
Pages: 2169-79
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Publication
27799550 | J:283483
First Author: Mathew G
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor.
Volume: 113
Issue: 46
Pages: 13156-13161
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Publication
27748998 | J:237426
First Author: Boucherat O
Year: 2017
Journal: Dev Dyn
Title: Lung development requires an active ERK/MAPK pathway in the lung mesenchyme.
Volume: 246
Issue: 1
Pages: 72-82
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Publication
14627958 | J:125580
 
First Author: Zhang L
Year: 2003
Journal: Mol Vis
Title: MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis.
Volume: 9
Pages: 584-93
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Publication
24361260 | J:206582
First Author: Ching ST
Year: 2014
Journal: Dev Biol
Title: Coordinated activity of Spry1 and Spry2 is required for normal development of the external genitalia.
Volume: 386
Issue: 1
Pages: 1-11
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Publication
15509711 | J:93217
First Author: Liu J
Year: 2004
Journal: Reproduction
Title: Serine-threonine kinases and transcription factors active in signal transduction are detected at high levels of phosphorylation during mitosis in preimplantation embryos and trophoblast stem cells.
Volume: 128
Issue: 5
Pages: 643-54
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Publication
15305288 | J:91734
First Author: Wang Y
Year: 2004
Journal: Dev Dyn
Title: Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos.
Volume: 231
Issue: 1
Pages: 72-87
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Publication
33277484 | J:300967
First Author: Pajovic S
Year: 2020
Journal: Nat Commun
Title: Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer.
Volume: 11
Issue: 1
Pages: 6216
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Publication
20019329 | J:170883
First Author: Huang J
Year: 2010
Journal: Circ Res
Title: Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression.
Volume: 106
Issue: 3
Pages: 583-92
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Publication
32428860 | J:336999
First Author: Riedelberger M
Year: 2020
Journal: iScience
Title: Type I Interferons Ameliorate Zinc Intoxication of Candida glabrata by Macrophages and Promote Fungal Immune Evasion.
Volume: 23
Issue: 5
Pages: 101121
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Publication
24733831 | J:213126
First Author: O'Donovan KJ
Year: 2014
Journal: J Exp Med
Title: B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS.
Volume: 211
Issue: 5
Pages: 801-14
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Publication
34428430 | J:314108
First Author: Jecrois ES
Year: 2021
Journal: Dev Cell
Title: Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.
Volume: 56
Issue: 20
Pages: 2871-2885.e6
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Publication
21965329 | J:178461
First Author: Pearson HB
Year: 2011
Journal: J Clin Invest
Title: SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.
Volume: 121
Issue: 11
Pages: 4257-67
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Publication
17396120 | J:121660
First Author: Zhong J
Year: 2007
Journal: Nat Neurosci
Title: Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo.
Volume: 10
Issue: 5
Pages: 598-607
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Publication
26633882 | J:269511
   
First Author: Roy A
Year: 2015
Journal: Elife
Title: Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy.
Volume: 4
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Publication
32075740 | J:349194
First Author: Riedelberger M
Year: 2020
Journal: Cell Host Microbe
Title: Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection.
Volume: 27
Issue: 3
Pages: 454-466.e8
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Publication
33227706 | J:308923
 
First Author: Li Z
Year: 2021
Journal: Biomed Pharmacother
Title: SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth.
Volume: 133
Pages: 111011
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Publication
38498715 | J:354182
First Author: Sun M
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period.
Volume: 121
Issue: 13
Pages: e2314802121
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Publication
30188892 | J:266214
First Author: Garg A
Year: 2018
Journal: PLoS Genet
Title: FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination.
Volume: 14
Issue: 9
Pages: e1007660
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Publication
32043969 | J:290269
   
First Author: Garg A
Year: 2020
Journal: Elife
Title: Etv transcription factors functionally diverge from their upstream FGF signaling in lens development.
Volume: 9
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Publication
24603431 | J:210997
First Author: Ihermann-Hella A
Year: 2014
Journal: PLoS Genet
Title: Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion.
Volume: 10
Issue: 3
Pages: e1004193
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Publication
25926459 | J:221658
First Author: Vithayathil J
Year: 2015
Journal: J Neurosci
Title: Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation.
Volume: 35
Issue: 17
Pages: 6836-48
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Publication
27122033 | J:231817
First Author: Matsumoto S
Year: 2016
Journal: J Neurosci
Title: Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development.
Volume: 36
Issue: 17
Pages: 4744-57
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Publication
19047410 | J:143745
First Author: Kamda JD
Year: 2009
Journal: Infect Immun
Title: Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia.
Volume: 77
Issue: 2
Pages: 685-93
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Publication
29028795 | J:246663
First Author: Garg A
Year: 2017
Journal: PLoS Genet
Title: Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis.
Volume: 13
Issue: 10
Pages: e1007047
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Publication
34757798 | J:314666
First Author: Balasubramanian R
Year: 2021
Journal: Sci Adv
Title: Phase transition specified by a binary code patterns the vertebrate eye cup.
Volume: 7
Issue: 46
Pages: eabj9846
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Publication
25100655 | J:214083
First Author: Boucherat O
Year: 2014
Journal: Development
Title: Crucial requirement of ERK/MAPK signaling in respiratory tract development.
Volume: 141
Issue: 16
Pages: 3197-211
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Publication
21220101 | J:264453
First Author: Newbern JM
Year: 2011
Journal: Neuron
Title: Specific functions for ERK/MAPK signaling during PNS development.
Volume: 69
Issue: 1
Pages: 91-105
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Publication
24431450 | J:205567
First Author: Li K
Year: 2014
Journal: J Neurosci
Title: Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum.
Volume: 34
Issue: 3
Pages: 922-31
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Publication
30220628 | J:333402
First Author: Ihermann-Hella A
Year: 2018
Journal: Stem Cell Reports
Title: Dynamic MAPK/ERK Activity Sustains Nephron Progenitors through Niche Regulation and Primes Precursors for Differentiation.
Volume: 11
Issue: 4
Pages: 912-928
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Publication
24982181 | J:212272
First Author: Wu J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis.
Volume: 111
Issue: 28
Pages: E2851-7
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Publication
32747435 | J:295894
 
First Author: Wei G
Year: 2020
Journal: Development
Title: Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation.
Volume: 147
Issue: 17
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 183
Description: Phosphothreonine; by MAP2K1 and MAP2K2
Type: modified residue
End: 183
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UniProt Feature
UniProt Feature
Begin: 185
Description: Phosphotyrosine; by MAP2K1 and MAP2K2
Type: modified residue
End: 185
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UniProt Feature
UniProt Feature
Begin: 203
Description: Phosphothreonine; by MAP2K1 and MAP2K2
Type: modified residue
End: 203
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UniProt Feature
UniProt Feature
Begin: 205
Description: Phosphotyrosine; by MAP2K1 and MAP2K2
Type: modified residue
End: 205
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DO Term
DOID:0111462 | cardiofaciocutaneous syndrome 3
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Allele
Map2k1<em1Smoc> | MGI:7290950
Name: mitogen-activated protein kinase kinase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
19602595 | J:150956
First Author: Nesbeth Y
Year: 2009
Journal: Cancer Res
Title: CCL5-mediated endogenous antitumor immunity elicited by adoptively transferred lymphocytes and dendritic cell depletion.
Volume: 69
Issue: 15
Pages: 6331-8
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Publication
26460096 | J:228517
First Author: Xing Y
Year: 2015
Journal: Dev Biol
Title: PTEN regulates lung endodermal morphogenesis through MEK/ERK pathway.
Volume: 408
Issue: 1
Pages: 56-65
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Publication
15016380 | J:88546
First Author: Kelleher RJ 3rd
Year: 2004
Journal: Cell
Title: Translational control by MAPK signaling in long-term synaptic plasticity and memory.
Volume: 116
Issue: 3
Pages: 467-79
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Publication
37842094 | J:341659
 
First Author: Fernandes LM
Year: 2023
Journal: Front Cell Dev Biol
Title: Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function.
Volume: 11
Pages: 1276333
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