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Search results 401 to 500 out of 540 for Map3k5

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
Probe: MGI:4423634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826082
Age: embryonic day 14.5
Image: euxassay_011097_14
Note: facial motor nucleus
Specimen Label: euxassay_011097_14
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:4423634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826082
Age: embryonic day 14.5
Image: euxassay_011097_15
Note: facial motor nucleus
Specimen Label: euxassay_011097_15
Detected: true
Specimen Num: 15
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•
GXD Expression
GXD Expression
 
Probe: MGI:4423634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826082
Age: embryonic day 14.5
Image: euxassay_011097_11
Specimen Label: euxassay_011097_11
Detected: true
Specimen Num: 11
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826082
Age: embryonic day 14.5
Image: euxassay_011097_12
Specimen Label: euxassay_011097_12
Detected: true
Specimen Num: 12
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423634
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826082
Age: embryonic day 14.5
Image: euxassay_011097_15
Specimen Label: euxassay_011097_15
Detected: true
Specimen Num: 15
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:3724872
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5421523
Age: embryonic day 14.5
Specimen Label: MH1464; Specimen C1143
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002080
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542634
Age: embryonic day 15.5
Image: GUDMAP:10540
Specimen Label: GUDMAP:10540
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002080
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542634
Age: embryonic day 15.5
Image: GUDMAP:10561
Specimen Label: GUDMAP:10561
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
     
Probe: MGI:3724872
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5421523
Age: embryonic day 14.5
Specimen Label: MH1464; Specimen C1143
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:3724872
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5421523
Age: embryonic day 14.5
Specimen Label: MH1464; Specimen C1143
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6287866
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6287869
Age: embryonic day 17.0
Specimen Label: 4B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6287868
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6287967
Age: embryonic day 17.0
Specimen Label: not shown
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3720343
Age: embryonic day 9.5
Image: 4B
Specimen Label: 4B
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3720343
Age: embryonic day 9.5
Image: 4B'
Specimen Label: 4B'
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
 
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3720343
Age: embryonic day 9.5
Image: 4B''
Specimen Label: 4B''
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
   
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3720343
Age: embryonic day 9.5
Specimen Label: Table 1 E9.5
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
   
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3720343
Age: embryonic day 10.5
Specimen Label: Table 1 E10.5
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
   
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:3720343
Age: embryonic day 11.5
Specimen Label: Table 1 E11.5
Detected: true
Specimen Num: 24
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002080
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542634
Age: embryonic day 15.5
Image: GUDMAP:10561
Specimen Label: GUDMAP:10561
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
Probe: MGI:3724872
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421523
Age: embryonic day 14.5
Image: MH1464; Specimen C1143
Note: Expression was weak in the skull (base and vault).
Specimen Label: MH1464; Specimen C1143
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689317
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3720343
Age: embryonic day 10.5
Image: 4C
Note: Expression is in the body wall enclosing the heart and nearby organs.
Specimen Label: 4C
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689317
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3720343
Age: embryonic day 10.5
Specimen Label: Table 1 E10.5
Detected: true
Specimen Num: 23
•
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:3720343
Age: embryonic day 11.5
Specimen Label: Table 1 E11.5
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3724872
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421523
Age: embryonic day 14.5
Image: MH1464; Specimen C1143
Note: Expression was detected in whisker follicle.
Specimen Label: MH1464; Specimen C1143
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3720337
Assay Type: RNA in situ
Annotation Date: 2007-09-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1657715
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3720343
Age: embryonic day 9.5
Image: 4B'''
Specimen Label: 4B'''
Detected: true
Specimen Num: 7
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Publication
17210579 | J:120898
First Author: Takeda K
Year: 2007
Journal: J Biol Chem
Title: Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1.
Volume: 282
Issue: 10
Pages: 7522-31
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Publication
32242025 | J:287157
First Author: Lucchini FC
Year: 2020
Journal: Nat Commun
Title: ASK1 inhibits browning of white adipose tissue in obesity.
Volume: 11
Issue: 1
Pages: 1642
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Publication
33108364 | J:296891
First Author: Hattori K
Year: 2020
Journal: PLoS One
Title: β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes.
Volume: 15
Issue: 10
Pages: e0232645
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Publication
19214184 | J:148044
First Author: Iriyama T
Year: 2009
Journal: EMBO J
Title: ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.
Volume: 28
Issue: 7
Pages: 843-53
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Publication
26243192 | J:258562
First Author: Okazaki T
Year: 2015
Journal: Sci Signal
Title: The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.
Volume: 8
Issue: 388
Pages: ra78
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Publication
33640602 | J:305766
 
First Author: Sun J
Year: 2021
Journal: Biochem Biophys Res Commun
Title: FBXW11 deletion alleviates Alzheimer's disease by reducing neuroinflammation and amyloid-β plaque formation via repression of ASK1 signaling.
Volume: 548
Pages: 104-111
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Publication
25628390 | J:234135
First Author: Huang Q
Year: 2015
Journal: Circulation
Title: Thioredoxin-2 inhibits mitochondrial reactive oxygen species generation and apoptosis stress kinase-1 activity to maintain cardiac function.
Volume: 131
Issue: 12
Pages: 1082-97
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Publication
19052195 | J:143058
First Author: Stetler RA
Year: 2008
Journal: J Neurosci
Title: Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling.
Volume: 28
Issue: 49
Pages: 13038-55
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Publication
16648474 | J:109068
First Author: Liu Q
Year: 2006
Journal: Mol Cell Biol
Title: Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth.
Volume: 26
Issue: 10
Pages: 3785-97
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Publication
17456047 | J:125559
First Author: Saito J
Year: 2007
Journal: Biochem J
Title: Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon.
Volume: 405
Issue: 3
Pages: 591-6
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Publication
27631783 | J:251158
First Author: Yamaguchi N
Year: 2016
Journal: PLoS One
Title: KLHDC10 Deficiency Protects Mice against TNFα-Induced Systemic Inflammation.
Volume: 11
Issue: 9
Pages: e0163118
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Publication
30961932 | J:291672
First Author: Tian H
Year: 2019
Journal: Biochem Biophys Res Commun
Title: SHP-1 inhibits renal ischemia reperfusion injury via dephosphorylating ASK1 and suppressing apoptosis.
Volume: 513
Issue: 2
Pages: 360-367
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Publication
20489729 | J:186353
First Author: Harada C
Year: 2010
Journal: Cell Death Differ
Title: ASK1 deficiency attenuates neural cell death in GLAST-deficient mice, a model of normal tension glaucoma.
Volume: 17
Issue: 11
Pages: 1751-9
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Publication
15467832 | J:93418
First Author: Yamaguchi O
Year: 2004
Journal: J Clin Invest
Title: Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis.
Volume: 114
Issue: 7
Pages: 937-43
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Publication
19597496 | J:151578
First Author: Kundu M
Year: 2009
Journal: Nat Immunol
Title: A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis.
Volume: 10
Issue: 8
Pages: 918-26
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Publication
19815822 | J:170149
First Author: Liu Q
Year: 2009
Journal: Circ Res
Title: ASK1 regulates cardiomyocyte death but not hypertrophy in transgenic mice.
Volume: 105
Issue: 11
Pages: 1110-7
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Publication
18676690 | J:141278
First Author: Ebrahimian T
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac hypertrophy is associated with altered thioredoxin and ASK-1 signaling in a mouse model of menopause.
Volume: 295
Issue: 4
Pages: H1481-8
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Publication
18195174 | J:145085
First Author: Taniike M
Year: 2008
Journal: Circulation
Title: Apoptosis signal-regulating kinase 1/p38 signaling pathway negatively regulates physiological hypertrophy.
Volume: 117
Issue: 4
Pages: 545-52
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Publication
19646509 | J:154511
First Author: Cho KJ
Year: 2009
Journal: Neuroscience
Title: Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease.
Volume: 163
Issue: 4
Pages: 1128-34
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Publication
24523853 | J:212947
First Author: Adekeye A
Year: 2014
Journal: PLoS One
Title: Ablation of the proapoptotic genes CHOP or Ask1 does not prevent or delay loss of visual function in a P23H transgenic mouse model of retinitis pigmentosa.
Volume: 9
Issue: 2
Pages: e83871
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Publication
35438255 | J:339005
First Author: Singh V
Year: 2022
Journal: Hepatol Commun
Title: Phosphoproteomics identifies pathways underlying the role of receptor-interaction protein kinase 3 in alcohol-associated liver disease and uncovers apoptosis signal-regulating kinase 1 as a target.
Volume: 6
Issue: 8
Pages: 2022-2041
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Publication
21187402 | J:169419
First Author: Hayakawa Y
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer.
Volume: 108
Issue: 2
Pages: 780-5
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Publication
16400028 | J:104441
First Author: Harada C
Year: 2006
Journal: Am J Pathol
Title: Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo.
Volume: 168
Issue: 1
Pages: 261-9
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Publication
29555767 | J:261077
First Author: Imamura K
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ASK family kinases mediate cellular stress and redox signaling to circadian clock.
Volume: 115
Issue: 14
Pages: 3646-3651
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Publication
28939911 | J:256561
First Author: Yoon KW
Year: 2017
Journal: Sci Rep
Title: CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1.
Volume: 7
Issue: 1
Pages: 12178
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Publication
25298527 | J:216585
First Author: Ma FY
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: ASK1/p38 signaling in renal tubular epithelial cells promotes renal fibrosis in the mouse obstructed kidney.
Volume: 307
Issue: 11
Pages: F1263-73
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Publication
17068291 | J:129085
First Author: Fan GC
Year: 2006
Journal: Circ Res
Title: Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1.
Volume: 99
Issue: 11
Pages: 1233-42
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Publication
19766627 | J:155494
First Author: Furuhata M
Year: 2009
Journal: Exp Cell Res
Title: Apoptosis signal-regulating kinase (ASK)-1 mediates apoptosis through activation of JNK1 following engagement of membrane immunoglobulin.
Volume: 315
Issue: 20
Pages: 3467-76
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Publication
19920149 | J:159953
First Author: Seong HA
Year: 2010
Journal: J Biol Chem
Title: Reciprocal negative regulation of PDK1 and ASK1 signaling by direct interaction and phosphorylation.
Volume: 285
Issue: 4
Pages: 2397-414
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Publication
21496457 | J:172060
First Author: Kwon JE
Year: 2011
Journal: FEBS Lett
Title: Stabilization of the survival motor neuron protein by ASK1.
Volume: 585
Issue: 9
Pages: 1287-92
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Publication
25752609 | J:222175
First Author: Watanabe T
Year: 2015
Journal: J Biol Chem
Title: Apoptosis Signal-regulating Kinase 1 (ASK1)-p38 Pathway-dependent Cytoplasmic Translocation of the Orphan Nuclear Receptor NR4A2 Is Required for Oxidative Stress-induced Necrosis.
Volume: 290
Issue: 17
Pages: 10791-803
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Publication
30172704 | J:267053
 
First Author: Cheon SY
Year: 2018
Journal: Neuroscience
Title: Apoptosis Signal-regulating Kinase 1 Silencing on Astroglial Inflammasomes in an Experimental Model of Ischemic Stroke.
Volume: 390
Pages: 218-230
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Publication
32544093 | J:306933
 
First Author: Ma J
Year: 2020
Journal: JCI Insight
Title: Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/p38MAPKα-dependent mechanisms.
Volume: 5
Issue: 14
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Publication
18948261 | J:143783
First Author: Jung H
Year: 2008
Journal: J Biol Chem
Title: Murine protein serine/threonine kinase 38 activates apoptosis signal-regulating kinase 1 via Thr 838 phosphorylation.
Volume: 283
Issue: 50
Pages: 34541-53
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Publication
16449798 | J:105801
First Author: Hsieh CC
Year: 2006
Journal: FASEB J
Title: Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice.
Volume: 20
Issue: 2
Pages: 259-68
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Publication
21527753 | J:191468
First Author: Yamada S
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Apoptosis signal-regulating kinase 1 deficiency accelerates hyperlipidemia-induced atheromatous plaques via suppression of macrophage apoptosis.
Volume: 31
Issue: 7
Pages: 1555-64
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Publication
16109778 | J:124062
First Author: Bijangi-Vishehsaraei K
Year: 2005
Journal: Blood
Title: Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1.
Volume: 106
Issue: 13
Pages: 4124-30
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Publication
26452228 | J:243688
First Author: Brobey RK
Year: 2015
Journal: PLoS One
Title: Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways.
Volume: 10
Issue: 10
Pages: e0139914
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Publication
17602894 | J:123567
First Author: Ferrer-Vaquer A
Year: 2007
Journal: Gene Expr Patterns
Title: Expression of ASK1 during chick and early mouse development.
Volume: 7
Issue: 7
Pages: 808-16
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Publication
28753204 | J:268897
First Author: Kamiyama M
Year: 2017
Journal: Cell Death Differ
Title: ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.
Volume: 24
Issue: 12
Pages: 2066-2076
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Publication
32445435 | J:307430
First Author: Xu X
Year: 2020
Journal: J Cell Mol Med
Title: ARRB1 ameliorates liver ischaemia/reperfusion injury via antagonizing TRAF6-mediated Lysine 6-linked polyubiquitination of ASK1 in hepatocytes.
Volume: 24
Issue: 14
Pages: 7814-7828
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Publication
28028021 | J:240103
First Author: Naik MU
Year: 2017
Journal: Blood
Title: Ask1 regulates murine platelet granule secretion, thromboxane A2 generation, and thrombus formation.
Volume: 129
Issue: 9
Pages: 1197-1209
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Publication
31996485 | J:283735
 
First Author: Schuster-Gaul S
Year: 2020
Journal: JCI Insight
Title: ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.
Volume: 5
Issue: 2
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Publication
18519638 | J:136428
First Author: Nishitoh H
Year: 2008
Journal: Genes Dev
Title: ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.
Volume: 22
Issue: 11
Pages: 1451-64
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Publication
29629899 | J:262879
First Author: Tartey S
Year: 2018
Journal: J Clin Invest
Title: ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.
Volume: 128
Issue: 5
Pages: 2042-2047
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Publication
20385180 | J:161867
First Author: Im JY
Year: 2010
Journal: Neurosci Res
Title: DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
Volume: 67
Issue: 3
Pages: 203-8
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Publication
19451227 | J:151342
First Author: Zhou J
Year: 2009
Journal: Mol Cell Biol
Title: Serine 58 of 14-3-3zeta is a molecular switch regulating ASK1 and oxidant stress-induced cell death.
Volume: 29
Issue: 15
Pages: 4167-76
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Publication
11959862 | J:77617
First Author: Zama T
Year: 2002
Journal: J Biol Chem
Title: Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway.
Volume: 277
Issue: 26
Pages: 23919-26
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Publication
12050113 | J:218004
First Author: Nishitoh H
Year: 2002
Journal: Genes Dev
Title: ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats.
Volume: 16
Issue: 11
Pages: 1345-55
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Publication
11154276 | J:121580
First Author: Kim AH
Year: 2001
Journal: Mol Cell Biol
Title: Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1.
Volume: 21
Issue: 3
Pages: 893-901
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Publication
33460648 | J:302170
   
First Author: Iorga A
Year: 2021
Journal: J Biol Chem
Title: Interaction of RIPK1 and A20 modulates MAPK signaling in murine acetaminophen toxicity.
Pages: 100300
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UniProt Feature
UniProt Feature
Begin: 401
Description: Phosphoserine; by MAP3K5
Type: modified residue
End: 401
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UniProt Feature
UniProt Feature
Begin: 397
Description: Phosphoserine; by MAP3K5
Type: modified residue
End: 397
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Publication
15864310 | J:98954
First Author: Matsuzawa A
Year: 2005
Journal: Nat Immunol
Title: ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.
Volume: 6
Issue: 6
Pages: 587-92
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Publication
14557248 | J:273504
First Author: Cho SG
Year: 2003
Journal: J Cell Biol
Title: Identification of a novel antiapoptotic protein that antagonizes ASK1 and CAD activities.
Volume: 163
Issue: 1
Pages: 71-81
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Publication
30024858 | J:266922
First Author: Liles JT
Year: 2018
Journal: J Clin Invest
Title: ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
Volume: 128
Issue: 10
Pages: 4485-4500
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Publication
23416061 | J:202436
First Author: Yamaguchi K
Year: 2013
Journal: Biochim Biophys Acta
Title: Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion.
Volume: 1830
Issue: 6
Pages: 3656-63
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Publication
18700144 | J:142119
First Author: Nakagawa H
Year: 2008
Journal: Gastroenterology
Title: Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation.
Volume: 135
Issue: 4
Pages: 1311-21
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Publication
25713304 | J:222130
First Author: Wu QQ
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-α/ASK1/JNK pathway.
Volume: 308
Issue: 9
Pages: H1143-54
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Publication
22337877 | J:184291
First Author: Tran P
Year: 2012
Journal: J Biol Chem
Title: TGF-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) interact with the promyogenic receptor Cdo to promote myogenic differentiation via activation of p38MAPK pathway.
Volume: 287
Issue: 15
Pages: 11602-15
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Publication
25135476 | J:224336
First Author: Gade P
Year: 2014
Journal: Mol Cell Biol
Title: Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1.
Volume: 34
Issue: 21
Pages: 4033-48
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Publication
27321923 | J:239629
First Author: Lee S
Year: 2016
Journal: Neuron
Title: Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis.
Volume: 91
Issue: 1
Pages: 41-55
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Publication
18007661 | J:146389
First Author: Wu YT
Year: 2008
Journal: Cell Death Differ
Title: Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death.
Volume: 15
Issue: 2
Pages: 386-97
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Publication
18776134 | J:157428
First Author: Kolliputi N
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation.
Volume: 40
Issue: 3
Pages: 314-24
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Publication
20200402 | J:162270
First Author: Hsu MJ
Year: 2010
Journal: J Leukoc Biol
Title: Apoptosis signal-regulating kinase 1 in peptidoglycan-induced COX-2 expression in macrophages.
Volume: 87
Issue: 6
Pages: 1069-82
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Publication
27450812 | J:238873
First Author: Pei B
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Quercetin ameliorates ischemia/reperfusion-induced cognitive deficits by inhibiting ASK1/JNK3/caspase-3 by enhancing the Akt signaling pathway.
Volume: 478
Issue: 1
Pages: 199-205
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Publication
16670275 | J:131688
First Author: Chiang E
Year: 2006
Journal: J Immunol
Title: Cutting edge: apoptosis-regulating signal kinase 1 is required for reactive oxygen species-mediated activation of IFN regulatory factor 3 by lipopolysaccharide.
Volume: 176
Issue: 10
Pages: 5720-4
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Publication
17219248 | J:122230
First Author: Gerits N
Year: 2007
Journal: Transgenic Res
Title: In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice.
Volume: 16
Issue: 3
Pages: 281-314
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Publication
29353059 | J:261112
First Author: Place DE
Year: 2018
Journal: Am J Pathol
Title: ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming.
Volume: 188
Issue: 4
Pages: 1021-1030
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Publication
19287004 | J:149742
First Author: Yu L
Year: 2009
Journal: J Biol Chem
Title: JAK2 and SHP2 reciprocally regulate tyrosine phosphorylation and stability of proapoptotic protein ASK1.
Volume: 284
Issue: 20
Pages: 13481-8
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Publication
15767678 | J:97560
First Author: Kelkar N
Year: 2005
Journal: Mol Cell Biol
Title: Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways.
Volume: 25
Issue: 7
Pages: 2733-43
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Publication
23319608 | J:193698
First Author: Li W
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.
Volume: 110
Issue: 5
Pages: 1738-43
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Publication
17015619 | J:114498
First Author: Gan B
Year: 2006
Journal: J Cell Biol
Title: Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways.
Volume: 175
Issue: 1
Pages: 121-33
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Publication
18855897 | J:141097
First Author: Craig EA
Year: 2008
Journal: Dev Dyn
Title: MAP3Ks as central regulators of cell fate during development.
Volume: 237
Issue: 11
Pages: 3102-14
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Publication
23982205 | J:260330
First Author: Yang P
Year: 2013
Journal: Sci Signal
Title: Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects.
Volume: 6
Issue: 290
Pages: ra74
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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