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Search results 401 to 500 out of 799 for Mmp13

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:7506284
Assay Type: RNA in situ
Annotation Date: 2023-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7506320
Age: embryonic day 16.5
Image: 5E WT
Note: Expression is in hypertrophic chondrocytes.
Specimen Label: 5E WT
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:7506284
Assay Type: RNA in situ
Annotation Date: 2023-07-11
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1914224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7506320
Age: embryonic day 16.5
Image: 5E Gadd45b<-/->
Note: In this mutant the number and distribution of expressing hypertrophic chondrocytes was reduced compared to wild-type.
Specimen Label: 5E Gadd45b<-/->
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:7546860
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7546921
Age: embryonic day 18.5
Image: 2D WT
Note: Expression in late hypertrophic chondrocytes.
Specimen Label: 2D WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7546860
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7546921
Age: embryonic day 15.5
Image: S2F WT
Specimen Label: S2F WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7546860
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1914223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7546921
Age: embryonic day 15.5
Image: S2F CKO
Note: Expression decreased compared to wild type.
Specimen Label: S2F CKO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7546860
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7546921
Age: embryonic day 18.5
Image: 2D CKO
Note: Expression increased significantly compared with wild type, indicating premature differentiation of chondrocytes.
Specimen Label: 2D CKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1340564
Assay Type: RNA in situ
Annotation Date: 2025-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7840090
Age: embryonic day 18.5
Note: Expression was detected in cells from the periosteal bud.
Specimen Label: 9e
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1340564
Assay Type: RNA in situ
Annotation Date: 2025-01-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7840090
Age: embryonic day 18.5
Note: Only a very low number of scattered cells located near the periosteal bud showed weak signal.
Specimen Label: 9g
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1340564
Assay Type: RNA in situ
Annotation Date: 2025-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7840090
Age: embryonic day 18.5
Note: Expression was weaker in the heterozygote compared with wild type.
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2013-04-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3550628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5472166
Age: postnatal week 2
Note: High level of expression in cells in the lower zone of hypertrophic chondrocytes in calcified cartilage.
Specimen Label: 6a/b
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:1340564
Assay Type: RNA in situ
Annotation Date: 2025-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7840090
Age: embryonic day 18.5
Note: Expression was detected in hypertrophic chondrocytes in the most distal portion of the epiphyses.
Specimen Label: 9e
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1340564
Assay Type: RNA in situ
Annotation Date: 2025-01-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3550626
Stage: TS26
Assay Id: MGI:7840090
Age: embryonic day 18.5
Specimen Label: 9g
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1340564
Assay Type: RNA in situ
Annotation Date: 2025-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7840090
Age: embryonic day 18.5
Note: Expression was weaker in the heterozygote hypertrophic chondrocytes in the most distal portion of the epiphyses compared with wild type.
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1801024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5472166
Age: embryonic day 16.5
Note: Expression in dorsal, but not in ventral, parts of ribs.
Specimen Label: 2a/b
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1801024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5472166
Age: embryonic day 16.5
Note: Expression in central region of clavicle, scapula and dorsal part of rib.
Specimen Label: 5a
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:5472173
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1801025
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5472174
Age: embryonic day 17.5
Note: Authors report expression at all sites identified by in situ hybridization (see assay MGI:5472166), such as dorsal areas of ribs, mandibular bone, metatarsals, and clavicle.
Specimen Label: not shown E17.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:16698
Assay Type: RNA in situ
Annotation Date: 2019-08-21
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6356412
Age: embryonic day 15.0
Note: Expression is in young chondroblasts in the dorsal ribs, weak in hypertrophied chondrocytes, and is absent in the ventral ribs.
Specimen Label: 2C/D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:16698
Assay Type: RNA in situ
Annotation Date: 2019-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1801025
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6356412
Age: embryonic day 17.0
Note: Expression is in the dorsal ribs in hypertrophied chondrocytes and is absent in immature chondrocytes.
Specimen Label: 2E/F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5472173
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3294025
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5472174
Age: embryonic day 17.5
Note: Expression in diaphysis of metatarsal bone.
Specimen Label: 4a
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5472173
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3294025
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5472174
Age: embryonic day 17.5
Note: Expression in diaphysis of metatarsal bone.
Specimen Label: 4b
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2023-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3657226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7545719
Age: embryonic day 18.5
Specimen Label: 6g
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2023-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3657226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7545719
Age: embryonic day 18.5
Note: Expressed in similar intensity but closer vicinity of the condylar apex in the mutants, compared with the wild-type.
Specimen Label: 6h
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:16698
Assay Type: RNA in situ
Annotation Date: 2019-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1767425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6356412
Age: embryonic day 17.0
Specimen Label: not shown, E17
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:16698
Assay Type: RNA in situ
Annotation Date: 2019-08-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1739221
Stage: TS21
Assay Id: MGI:6356412
Age: embryonic day 13.0
Specimen Label: 2A/B
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5447310
Assay Type: RNA in situ
Annotation Date: 2013-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5447320
Age: embryonic day 18.25
Image: 2B mmp13/cbfa1
Note: No expression in periosteum.
Specimen Label: 2B mmp13/cbfa1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4423650
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1829123
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826404
Age: embryonic day 14.5
Image: euxassay_009345_10
Specimen Label: euxassay_009345_10
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423650
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1829123
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826404
Age: embryonic day 14.5
Image: euxassay_009345_11
Specimen Label: euxassay_009345_11
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423650
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1829123
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826404
Age: embryonic day 14.5
Image: euxassay_009345_16
Specimen Label: euxassay_009345_16
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423650
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1829123
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826404
Age: embryonic day 14.5
Image: euxassay_009345_17
Specimen Label: euxassay_009345_17
Detected: true
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423650
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1829123
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826404
Age: embryonic day 14.5
Image: euxassay_009345_18
Specimen Label: euxassay_009345_18
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5429519
Assay Type: Immunohistochemistry
Annotation Date: 2012-07-30
Strength: Present
Sex: Male
Emaps: EMAPS:3273023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5429521
Age: embryonic day 15.5
Image: 7 Ror2+/+
Note: Expression is in the ossification centers.
Specimen Label: 7 Ror2+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5429519
Assay Type: Immunohistochemistry
Annotation Date: 2012-07-30
Strength: Absent
Sex: Male
Emaps: EMAPS:3273023
Stage: TS23
Assay Id: MGI:5429521
Age: embryonic day 15.5
Image: 7 Ror2-/-
Specimen Label: 7 Ror2-/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6711296
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3273024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6711298
Age: embryonic day 16.5
Note: Expressin is in hypertrophic zones.
Specimen Label: 1g
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6711296
Assay Type: Immunohistochemistry
Annotation Date: 2021-05-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3273024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6711298
Age: embryonic day 16.5
Note: Expression in hypertrophic zones has increased in this mutant compared to wild-type.
Specimen Label: 1k
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4423650
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1793723
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826404
Age: embryonic day 14.5
Image: euxassay_009345_10
Specimen Label: euxassay_009345_10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4423650
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1793723
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826404
Age: embryonic day 14.5
Image: euxassay_009345_11
Specimen Label: euxassay_009345_11
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423650
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1793723
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826404
Age: embryonic day 14.5
Image: euxassay_009345_17
Specimen Label: euxassay_009345_17
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4423650
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1793723
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4826404
Age: embryonic day 14.5
Image: euxassay_009345_18
Specimen Label: euxassay_009345_18
Detected: true
Specimen Num: 5
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1872224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5472166
Age: embryonic day 16.5
Specimen Label: not shown E16.5
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
 
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1872224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5472166
Age: embryonic day 16.5
Note: Expression in central region of clavicle, scapula and dorsal part of rib.
Specimen Label: 5a
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:16698
Assay Type: RNA in situ
Annotation Date: 2019-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1872225
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6356412
Age: embryonic day 17.0
Note: Expression is in a narrow band of the dorsal part in hypertrophied chondrocytes and is absent in immature chondrocytes.
Specimen Label: 2E/F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6361577
Assay Type: RNA in situ
Annotation Date: 2019-10-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6361661
Age: embryonic day 16.5
Image: 6i
Note: Expression is in the perichondrium of the bone collar of the mandible.
Specimen Label: 6i
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:16698
Assay Type: RNA in situ
Annotation Date: 2019-08-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:6356412
Age: embryonic day 15.0
Specimen Label: 2C/D
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768124
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5472166
Age: embryonic day 16.5
Note: Expression in the base of the skull (exoccipital).
Specimen Label: not shown E16.5
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1763924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5472166
Age: embryonic day 16.5
Specimen Label: not shown E16.5
Detected: true
Specimen Num: 10
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5472160
Assay Type: RNA in situ
Annotation Date: 2013-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1763922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5472166
Age: embryonic day 14.5
Note: Expression first detected at E14.5.
Specimen Label: 1a
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:16698
Assay Type: RNA in situ
Annotation Date: 2019-08-21
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1768023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6356412
Age: embryonic day 15.0
Note: Expression is in hypertrophied chondrocytes and is absent in immature cartilagenous matrix.
Specimen Label: 2C/D
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:16698
Assay Type: RNA in situ
Annotation Date: 2019-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3724525
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6356412
Age: embryonic day 17.0
Note: Expression is in the cartilaginous matrix in hypertrophied chondrocytes and is absent in immature chondrocytes.
Specimen Label: 2E/F
Detected: true
Specimen Num: 3
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Publication
25964075 | J:317046
 
First Author: Niebler S
Year: 2015
Journal: Arthritis Res Ther
Title: Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development.
Volume: 17
Pages: 119
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Publication
19590036 | J:150790
First Author: Hattori N
Year: 2009
Journal: Am J Pathol
Title: MMP-13 plays a role in keratinocyte migration, angiogenesis, and contraction in mouse skin wound healing.
Volume: 175
Issue: 2
Pages: 533-46
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Publication
9425170 | J:45379
First Author: Carmeliet P
Year: 1998
Journal: J Cell Biol
Title: Receptor-independent role of urokinase-type plasminogen activator in pericellular plasmin and matrix metalloproteinase proteolysis during vascular wound healing in mice.
Volume: 140
Issue: 1
Pages: 233-45
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Publication
26474296 | J:244228
First Author: Goto H
Year: 2015
Journal: PLoS One
Title: Interleukin-1 Receptor Antagonist Has a Novel Function in the Regulation of Matrix Metalloproteinase-13 Expression.
Volume: 10
Issue: 10
Pages: e0140942
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Publication
15507443 | J:94563
First Author: Kong W
Year: 2004
Journal: J Biol Chem
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