Type |
Details |
Score |
Publication |
First Author: |
González IM |
Year: |
2012 |
Journal: |
Dev Biol |
Title: |
Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo. |
Volume: |
361 |
Issue: |
2 |
Pages: |
286-300 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Q |
Year: |
2020 |
Journal: |
Immunol Cell Biol |
Title: |
Hyperglycemia aggravates acute liver injury by promoting liver-resident macrophage NLRP3 inflammasome activation via the inhibition of AMPK/mTOR-mediated autophagy induction. |
Volume: |
98 |
Issue: |
1 |
Pages: |
54-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leontieva OV |
Year: |
2012 |
Journal: |
Aging (Albany NY) |
Title: |
Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging. |
Volume: |
4 |
Issue: |
12 |
Pages: |
899-916 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tao H |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals. |
Volume: |
12 |
Issue: |
1 |
Pages: |
2029 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lamming DW |
Year: |
2014 |
Journal: |
Aging Cell |
Title: |
Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan. |
Volume: |
13 |
Issue: |
5 |
Pages: |
911-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iwata TN |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism. |
Volume: |
197 |
Issue: |
6 |
Pages: |
2250-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Drägert K |
Year: |
2016 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue. |
Volume: |
473 |
Issue: |
1 |
Pages: |
317-322 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carson RP |
Year: |
2013 |
Journal: |
Hum Mol Genet |
Title: |
Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex. |
Volume: |
22 |
Issue: |
1 |
Pages: |
140-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li D |
Year: |
2016 |
Journal: |
FASEB J |
Title: |
mTORC1 pathway disruption ameliorates brain inflammation following stroke via a shift in microglia phenotype from M1 type to M2 type. |
Volume: |
30 |
Issue: |
10 |
Pages: |
3388-3399 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baffi TR |
Year: |
2021 |
Journal: |
Sci Signal |
Title: |
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif. |
Volume: |
14 |
Issue: |
678 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Oh WJ |
Year: |
2010 |
Journal: |
EMBO J |
Title: |
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide. |
Volume: |
29 |
Issue: |
23 |
Pages: |
3939-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miao L |
Year: |
2016 |
Journal: |
Elife |
Title: |
mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system. |
Volume: |
5 |
|
Pages: |
e14908 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng M |
Year: |
2011 |
Journal: |
Nat Cell Biol |
Title: |
Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1. |
Volume: |
13 |
Issue: |
3 |
Pages: |
263-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie X |
Year: |
2018 |
Journal: |
Nat Cell Biol |
Title: |
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168. |
Volume: |
20 |
Issue: |
3 |
Pages: |
320-331 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bernardi R |
Year: |
2011 |
Journal: |
EMBO Mol Med |
Title: |
Pml represses tumour progression through inhibition of mTOR. |
Volume: |
3 |
Issue: |
5 |
Pages: |
249-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmitz F |
Year: |
2008 |
Journal: |
Eur J Immunol |
Title: |
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells. |
Volume: |
38 |
Issue: |
11 |
Pages: |
2981-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robert F |
Year: |
2012 |
Journal: |
Cancer Res |
Title: |
Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival. |
Volume: |
72 |
Issue: |
3 |
Pages: |
747-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schewe DM |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo. |
Volume: |
105 |
Issue: |
30 |
Pages: |
10519-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weichhart T |
Year: |
2008 |
Journal: |
Immunity |
Title: |
The TSC-mTOR signaling pathway regulates the innate inflammatory response. |
Volume: |
29 |
Issue: |
4 |
Pages: |
565-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
La P |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation stabilizes ISCU protein: implications for iron metabolism. |
Volume: |
288 |
Issue: |
18 |
Pages: |
12901-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu FY |
Year: |
2023 |
Journal: |
J Inflamm Res |
Title: |
Rapamycin Exacerbates Staphylococcus aureus Pneumonia by Inhibiting mTOR-RPS6 in Macrophages. |
Volume: |
16 |
|
Pages: |
5715-5728 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deason K |
Year: |
2018 |
Journal: |
J Exp Med |
Title: |
BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation. |
Volume: |
215 |
Issue: |
9 |
Pages: |
2413-2428 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borsting E |
Year: |
2014 |
Journal: |
J Am Soc Nephrol |
Title: |
Tribbles homolog 3 attenuates mammalian target of rapamycin complex-2 signaling and inflammation in the diabetic kidney. |
Volume: |
25 |
Issue: |
9 |
Pages: |
2067-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen B |
Year: |
2021 |
Journal: |
Front Physiol |
Title: |
Selective Deletion of the Mechanistic Target of Rapamycin From the Renal Collecting Duct Principal Cell in Mice Down-Regulates the Epithelial Sodium Channel. |
Volume: |
12 |
|
Pages: |
787521 |
|
•
•
•
•
•
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Publication |
First Author: |
Rodriguez Y |
Year: |
2022 |
Journal: |
Liver Res |
Title: |
Liver-adipose tissue crosstalk in alcohol-associated liver disease: The role of mTOR. |
Volume: |
6 |
Issue: |
4 |
Pages: |
227-237 |
|
•
•
•
•
•
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Publication |
First Author: |
Jarmas AE |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Progenitor translatome changes coordinated by Tsc1 increase perception of Wnt signals to end nephrogenesis. |
Volume: |
12 |
Issue: |
1 |
Pages: |
6332 |
|
•
•
•
•
•
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Publication |
First Author: |
Zhu L |
Year: |
2014 |
Journal: |
Nat Commun |
Title: |
TSC1 controls macrophage polarization to prevent inflammatory disease. |
Volume: |
5 |
|
Pages: |
4696 |
|
•
•
•
•
•
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Publication |
First Author: |
Lee D |
Year: |
2014 |
Journal: |
Stem Cell Reports |
Title: |
Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors. |
Volume: |
3 |
Issue: |
5 |
Pages: |
832-40 |
|
•
•
•
•
•
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Publication |
First Author: |
Huang H |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis. |
Volume: |
42 |
Issue: |
7 |
Pages: |
112801 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen J |
Year: |
2014 |
Journal: |
Development |
Title: |
mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis. |
Volume: |
141 |
Issue: |
14 |
Pages: |
2848-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gui Y |
Year: |
2018 |
Journal: |
J Biol Chem |
Title: |
Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis. |
Volume: |
293 |
Issue: |
42 |
Pages: |
16364-16375 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li S |
Year: |
2016 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Promoting axon regeneration in the adult CNS by modulation of the melanopsin/GPCR signaling. |
Volume: |
113 |
Issue: |
7 |
Pages: |
1937-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ni HM |
Year: |
2019 |
Journal: |
Hepatology |
Title: |
Dual Roles of Mammalian Target of Rapamycin in Regulating Liver Injury and Tumorigenesis in Autophagy-Defective Mouse Liver. |
Volume: |
70 |
Issue: |
6 |
Pages: |
2142-2155 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen LC |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells. |
Volume: |
197 |
Issue: |
4 |
Pages: |
1137-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dai Q |
Year: |
2017 |
Journal: |
Cell Death Differ |
Title: |
mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression. |
Volume: |
24 |
Issue: |
11 |
Pages: |
1886-1899 |
|
•
•
•
•
•
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Publication |
First Author: |
Araujo A |
Year: |
2021 |
Journal: |
Elife |
Title: |
IFN-γ mediates Paneth cell death via suppression of mTOR. |
Volume: |
10 |
|
|
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•
•
•
•
•
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Publication |
First Author: |
Carter HN |
Year: |
2012 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Contractile activity-induced mitochondrial biogenesis and mTORC1. |
Volume: |
303 |
Issue: |
5 |
Pages: |
C540-7 |
|
•
•
•
•
•
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Publication |
First Author: |
Xie C |
Year: |
2007 |
Journal: |
Int Immunol |
Title: |
PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr. |
Volume: |
19 |
Issue: |
4 |
Pages: |
509-22 |
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•
•
•
•
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Publication |
First Author: |
Ivanov SS |
Year: |
2013 |
Journal: |
Nat Immunol |
Title: |
Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR. |
Volume: |
14 |
Issue: |
12 |
Pages: |
1219-28 |
|
•
•
•
•
•
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Publication |
First Author: |
Saci A |
Year: |
2011 |
Journal: |
Mol Cell |
Title: |
Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size. |
Volume: |
42 |
Issue: |
1 |
Pages: |
50-61 |
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•
•
•
•
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Publication |
First Author: |
Nardella C |
Year: |
2011 |
Journal: |
Cancer Res |
Title: |
Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis. |
Volume: |
71 |
Issue: |
10 |
Pages: |
3669-75 |
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•
•
•
•
•
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Publication |
First Author: |
Rieker C |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling. |
Volume: |
31 |
Issue: |
2 |
Pages: |
453-60 |
|
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•
•
•
•
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Publication |
First Author: |
Daley SR |
Year: |
2013 |
Journal: |
Elife |
Title: |
Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies. |
Volume: |
2 |
|
Pages: |
e01020 |
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•
•
•
•
•
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Publication |
First Author: |
Liao CY |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Rapamycin Reverses Metabolic Deficits in Lamin A/C-Deficient Mice. |
Volume: |
17 |
Issue: |
10 |
Pages: |
2542-2552 |
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•
•
•
•
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Publication |
First Author: |
Bartley CM |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity. |
Volume: |
9 |
Issue: |
5 |
Pages: |
e96956 |
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•
•
•
•
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Publication |
First Author: |
Ghosh HS |
Year: |
2010 |
Journal: |
PLoS One |
Title: |
SIRT1 negatively regulates the mammalian target of rapamycin. |
Volume: |
5 |
Issue: |
2 |
Pages: |
e9199 |
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•
•
•
•
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Publication |
First Author: |
Pema M |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex. |
Volume: |
7 |
|
Pages: |
10786 |
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•
•
•
•
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Publication |
First Author: |
Xing X |
Year: |
2020 |
Journal: |
Neuropharmacology |
Title: |
Hyperactive Akt-mTOR pathway as a therapeutic target for pain hypersensitivity in Cntnap2-deficient mice. |
Volume: |
165 |
|
Pages: |
107816 |
|
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•
•
•
•
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Publication |
First Author: |
Yeager N |
Year: |
2008 |
Journal: |
Cancer Res |
Title: |
Mammalian target of rapamycin is the key effector of phosphatidylinositol-3-OH-initiated proliferative signals in the thyroid follicular epithelium. |
Volume: |
68 |
Issue: |
2 |
Pages: |
444-9 |
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•
•
•
•
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Publication |
First Author: |
Ozcan U |
Year: |
2008 |
Journal: |
Mol Cell |
Title: |
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis. |
Volume: |
29 |
Issue: |
5 |
Pages: |
541-51 |
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•
•
•
•
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Publication |
First Author: |
Khayati K |
Year: |
2017 |
Journal: |
FASEB J |
Title: |
The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice. |
Volume: |
31 |
Issue: |
2 |
Pages: |
598-609 |
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•
•
•
•
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Publication |
First Author: |
Zhao C |
Year: |
2011 |
Journal: |
J Clin Invest |
Title: |
mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice. |
Volume: |
121 |
Issue: |
1 |
Pages: |
369-83 |
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•
•
•
•
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Publication |
First Author: |
Mori H |
Year: |
2009 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Critical roles for the TSC-mTOR pathway in β-cell function. |
Volume: |
297 |
Issue: |
5 |
Pages: |
E1013-22 |
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•
•
•
•
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Publication |
First Author: |
Ruffolo SC |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice. |
Volume: |
282 |
Issue: |
42 |
Pages: |
30423-33 |
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•
•
•
•
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Publication |
First Author: |
Li Y |
Year: |
2021 |
Journal: |
Development |
Title: |
Regulation of the mammalian maternal-to-embryonic transition by eukaryotic translation initiation factor 4E. |
Volume: |
148 |
Issue: |
12 |
|
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•
•
•
•
•
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Publication |
First Author: |
Riddle RC |
Year: |
2014 |
Journal: |
Mol Cell Biol |
Title: |
Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis. |
Volume: |
34 |
Issue: |
10 |
Pages: |
1850-62 |
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•
•
•
•
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Publication |
First Author: |
Houssaini A |
Year: |
2016 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension. |
Volume: |
55 |
Issue: |
3 |
Pages: |
352-67 |
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•
•
•
•
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Publication |
First Author: |
Puelles VG |
Year: |
2019 |
Journal: |
JCI Insight |
Title: |
mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans. |
Volume: |
4 |
Issue: |
18 |
|
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•
•
•
•
•
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Publication |
First Author: |
Asao R |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Rac1 in podocytes promotes glomerular repair and limits the formation of sclerosis. |
Volume: |
8 |
Issue: |
1 |
Pages: |
5061 |
|
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•
•
•
•
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Publication |
First Author: |
Chen Z |
Year: |
2014 |
Journal: |
J Am Soc Nephrol |
Title: |
Activation of mTORC1 in collecting ducts causes hyperkalemia. |
Volume: |
25 |
Issue: |
3 |
Pages: |
534-45 |
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•
•
•
•
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Publication |
First Author: |
You JS |
Year: |
2014 |
Journal: |
J Biol Chem |
Title: |
The role of diacylglycerol kinase ζ and phosphatidic acid in the mechanical activation of mammalian target of rapamycin (mTOR) signaling and skeletal muscle hypertrophy. |
Volume: |
289 |
Issue: |
3 |
Pages: |
1551-63 |
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•
•
•
•
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Publication |
First Author: |
Mounier R |
Year: |
2009 |
Journal: |
FASEB J |
Title: |
Important role for AMPKalpha1 in limiting skeletal muscle cell hypertrophy. |
Volume: |
23 |
Issue: |
7 |
Pages: |
2264-73 |
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•
•
•
•
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Publication |
First Author: |
Shimada BK |
Year: |
2021 |
Journal: |
Physiol Rep |
Title: |
mTOR-mediated calcium transients affect cardiac function in ex vivo ischemia-reperfusion injury. |
Volume: |
9 |
Issue: |
6 |
Pages: |
e14807 |
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•
•
•
•
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Publication |
First Author: |
Wahl SE |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination. |
Volume: |
34 |
Issue: |
13 |
Pages: |
4453-65 |
|
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•
•
•
•
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Publication |
First Author: |
Webb LM |
Year: |
2019 |
Journal: |
Front Immunol |
Title: |
NF-κB/mTOR/MYC Axis Drives PRMT5 Protein Induction After T Cell Activation via Transcriptional and Non-transcriptional Mechanisms. |
Volume: |
10 |
|
Pages: |
524 |
|
•
•
•
•
•
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Publication |
First Author: |
Nadon AM |
Year: |
2014 |
Journal: |
Am J Pathol |
Title: |
Rtp801 suppression of epithelial mTORC1 augments endotoxin-induced lung inflammation. |
Volume: |
184 |
Issue: |
9 |
Pages: |
2382-9 |
|
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•
•
•
•
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Publication |
First Author: |
Gordon BS |
Year: |
2014 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Reduced REDD1 expression contributes to activation of mTORC1 following electrically induced muscle contraction. |
Volume: |
307 |
Issue: |
8 |
Pages: |
E703-11 |
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•
•
•
•
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Publication |
First Author: |
Xiong Y |
Year: |
2017 |
Journal: |
EBioMedicine |
Title: |
Peripheral Neuropathy and Hindlimb Paralysis in a Mouse Model of Adipocyte-Specific Knockout of Lkb1. |
Volume: |
24 |
|
Pages: |
127-136 |
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•
•
•
•
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Publication |
First Author: |
Bodur C |
Year: |
2018 |
Journal: |
EMBO J |
Title: |
The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists. |
Volume: |
37 |
Issue: |
1 |
Pages: |
19-38 |
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•
•
•
•
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Publication |
First Author: |
Tooley AS |
Year: |
2021 |
Journal: |
J Biol Chem |
Title: |
The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt. |
Volume: |
297 |
Issue: |
2 |
Pages: |
100942 |
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•
•
•
•
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Publication |
First Author: |
Lin JT |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression. |
Volume: |
182 |
Issue: |
10 |
Pages: |
5919-28 |
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•
•
•
•
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Publication |
First Author: |
Agrawal P |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR). |
Volume: |
287 |
Issue: |
25 |
Pages: |
21164-75 |
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•
•
•
•
•
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Publication |
First Author: |
Hernández G |
Year: |
2011 |
Journal: |
Exp Cell Res |
Title: |
A novel cardioprotective p38-MAPK/mTOR pathway. |
Volume: |
317 |
Issue: |
20 |
Pages: |
2938-49 |
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•
•
•
•
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Publication |
First Author: |
Chen CJ |
Year: |
2019 |
Journal: |
Nat Med |
Title: |
Therapeutic inhibition of mTORC2 rescues the behavioral and neurophysiological abnormalities associated with Pten-deficiency. |
Volume: |
25 |
Issue: |
11 |
Pages: |
1684-1690 |
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•
•
•
•
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Publication |
First Author: |
Patursky-Polischuk I |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner. |
Volume: |
29 |
Issue: |
3 |
Pages: |
640-9 |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
256
 |
Fragment?: |
false |
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•
•
•
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Publication |
First Author: |
Harris TE |
Year: |
2006 |
Journal: |
EMBO J |
Title: |
mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin. |
Volume: |
25 |
Issue: |
8 |
Pages: |
1659-68 |
|
•
•
•
•
•
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Publication |
First Author: |
Liu G |
Year: |
2010 |
Journal: |
Nat Immunol |
Title: |
The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells. |
Volume: |
11 |
Issue: |
11 |
Pages: |
1047-56 |
|
•
•
•
•
•
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Publication |
First Author: |
Essig K |
Year: |
2017 |
Journal: |
Immunity |
Title: |
Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells. |
Volume: |
47 |
Issue: |
6 |
Pages: |
1067-1082.e12 |
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•
•
•
•
•
|
Publication |
First Author: |
Gulen MF |
Year: |
2012 |
Journal: |
Immunity |
Title: |
Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance. |
Volume: |
37 |
Issue: |
5 |
Pages: |
800-12 |
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•
•
•
•
•
|
Publication |
First Author: |
González-Fernández E |
Year: |
2018 |
Journal: |
Elife |
Title: |
PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling. |
Volume: |
7 |
|
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•
•
•
•
•
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Publication |
First Author: |
Marabita M |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
S6K1 Is Required for Increasing Skeletal Muscle Force during Hypertrophy. |
Volume: |
17 |
Issue: |
2 |
Pages: |
501-513 |
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•
•
•
•
•
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Publication |
First Author: |
Cam H |
Year: |
2010 |
Journal: |
Mol Cell |
Title: |
mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α. |
Volume: |
40 |
Issue: |
4 |
Pages: |
509-20 |
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•
•
•
•
•
|
Publication |
First Author: |
Floyd S |
Year: |
2007 |
Journal: |
Mol Biol Cell |
Title: |
The insulin-like growth factor-I-mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth. |
Volume: |
18 |
Issue: |
9 |
Pages: |
3545-55 |
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•
•
•
•
•
|
Publication |
First Author: |
Lu M |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel. |
Volume: |
286 |
Issue: |
35 |
Pages: |
30647-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun X |
Year: |
2012 |
Journal: |
Gastroenterology |
Title: |
Campylobacter jejuni induces colitis through activation of mammalian target of rapamycin signaling. |
Volume: |
142 |
Issue: |
1 |
Pages: |
86-95.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hentges KE |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse. |
Volume: |
98 |
Issue: |
24 |
Pages: |
13796-801 |
|
•
•
•
•
•
|
Publication |
First Author: |
Orr ME |
Year: |
2014 |
Journal: |
Neurobiol Aging |
Title: |
Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology. |
Volume: |
35 |
Issue: |
6 |
Pages: |
1233-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Linder M |
Year: |
2018 |
Journal: |
Cell Death Differ |
Title: |
EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation. |
Volume: |
25 |
Issue: |
6 |
Pages: |
1094-1106 |
|
•
•
•
•
•
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Publication |
First Author: |
Donahue AC |
Year: |
2007 |
Journal: |
Eur J Immunol |
Title: |
Distinct signaling mechanisms activate the target of rapamycin in response to different B-cell stimuli. |
Volume: |
37 |
Issue: |
10 |
Pages: |
2923-36 |
|
•
•
•
•
•
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Publication |
First Author: |
Lee DH |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
Mammalian target of rapamycin's distinct roles and effectiveness in promoting compensatory axonal sprouting in the injured CNS. |
Volume: |
34 |
Issue: |
46 |
Pages: |
15347-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson C |
Year: |
2006 |
Journal: |
Cancer Res |
Title: |
Tsc1 haploinsufficiency without mammalian target of rapamycin activation is sufficient for renal cyst formation in Tsc1+/- mice. |
Volume: |
66 |
Issue: |
16 |
Pages: |
7934-8 |
|
•
•
•
•
•
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Publication |
First Author: |
Zhang D |
Year: |
2010 |
Journal: |
J Clin Invest |
Title: |
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. |
Volume: |
120 |
Issue: |
8 |
Pages: |
2805-16 |
|
•
•
•
•
•
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Publication |
First Author: |
Hodges SL |
Year: |
2018 |
Journal: |
Neuroreport |
Title: |
Molecular interplay between hyperactive mammalian target of rapamycin signaling and Alzheimer's disease neuropathology in the NS-Pten knockout mouse model. |
Volume: |
29 |
Issue: |
13 |
Pages: |
1109-1113 |
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•
•
•
•
•
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Publication |
First Author: |
Zhou AC |
Year: |
2019 |
Journal: |
J Immunol |
Title: |
4-1BB Regulates Effector CD8 T Cell Accumulation in the Lung Tissue through a TRAF1-, mTOR-, and Antigen-Dependent Mechanism to Enhance Tissue-Resident Memory T Cell Formation during Respiratory Influenza Infection. |
Volume: |
202 |
Issue: |
8 |
Pages: |
2482-2492 |
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•
•
•
•
•
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Publication |
First Author: |
Pastor MD |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia. |
Volume: |
284 |
Issue: |
33 |
Pages: |
22067-78 |
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•
•
•
•
•
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Publication |
First Author: |
Gleason CE |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity. |
Volume: |
125 |
Issue: |
1 |
Pages: |
117-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang M |
Year: |
2018 |
Journal: |
Glia |
Title: |
The TSC1-mTOR-PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage-specific manner. |
Volume: |
66 |
Issue: |
9 |
Pages: |
1947-1959 |
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•
•
•
•
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Publication |
First Author: |
Wang Y |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Nesfatin-1 promotes brown adipocyte phenotype. |
Volume: |
6 |
|
Pages: |
34747 |
|
•
•
•
•
•
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Publication |
First Author: |
Simonson B |
Year: |
2017 |
Journal: |
Sci Signal |
Title: |
DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress. |
Volume: |
10 |
Issue: |
468 |
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•
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•
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