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Search results 401 to 483 out of 483 for Myocd

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Type Details Score
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Myocd<em1H> | MGI:6716308
Name: myocardin; endonuclease-mediated mutation 1, Harwell
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Myocd<em2H> | MGI:6741028
Name: myocardin; endonuclease-mediated mutation 2, Harwell
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6716309 | C57BL/6J-Myocd<em1H>/H
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6741029 | C57BL/6NTac-Myocd<em2H>/H
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Myocd/Myocd<+> mgb/?
Background: involves: 129/Sv * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Allele
Gt(ROSA)26Sor<tm1(Myocd)Jomm> | MGI:7529625
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Joseph M Miano
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence
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Genotype
Genotype
Symbol: Myocd/Myocd
Background: involves: 129
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0112014 | congenital megabladder
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Allele
Myocd<tm1(cre)Jomm> | MGI:3849559
Name: myocardin; targeted mutation 1, Joseph M Miano
Allele Type: Targeted
Attribute String: Recombinase
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Strain
MGI:4946638 | STOCK Myocd<tm1(cre)Jomm>/J
Attribute String: targeted mutation, mutant stock
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Genotype
Genotype
Symbol: Myocd/Myocd<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Allele
mgb | MGI:3772357
 
Name: megabladder
Allele Type: Transgenic
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Publication
19098903 | J:187572
First Author: Bell RD
Year: 2009
Journal: Nat Cell Biol
Title: SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells.
Volume: 11
Issue: 2
Pages: 143-53
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HT Experiment
GSE15232 | A Regulatory Pathway Involving Notch1/beta-Catenin/Isl1 Determines Cardiac Progenitor Cell Fate
Series Id: E-GEOD-15232
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Publication
17202422 | J:130545
First Author: Singh S
Year: 2007
Journal: J Am Soc Nephrol
Title: Identification of a unique transgenic mouse line that develops megabladder, obstructive uropathy, and renal dysfunction.
Volume: 18
Issue: 2
Pages: 461-71
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Publication
18069694 | J:130365
First Author: Singh S
Year: 2008
Journal: Dev Dyn
Title: Transcriptional profiling of the megabladder mouse: a unique model of bladder dysmorphogenesis.
Volume: 237
Issue: 1
Pages: 170-86
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Publication
20736884 | J:292557
First Author: Ingraham SE
Year: 2010
Journal: Pediatr Res
Title: Pathogenesis of renal injury in the megabladder mouse: a genetic model of congenital obstructive nephropathy.
Volume: 68
Issue: 6
Pages: 500-7
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Publication
27384406 | J:292559
First Author: Wilhide ME
Year: 2016
Journal: Pediatr Res
Title: Renal epithelial miR-205 expression correlates with disease severity in a mouse model of congenital obstructive nephropathy.
Volume: 80
Issue: 4
Pages: 602-9
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Publication
23523293 | J:292560
First Author: Becknell B
Year: 2013
Journal: Urology
Title: Struvite urolithiasis and chronic urinary tract infection in a murine model of urinary diversion.
Volume: 81
Issue: 5
Pages: 943-8
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Publication
29410288 | J:292561
 
First Author: Xin G
Year: 2018
Journal: Gene
Title: Identification of key microRNAs, transcription factors and genes associated with congenital obstructive nephropathy in a mouse model of megabladder.
Volume: 650
Pages: 77-85
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Publication
24276861 | J:292558
First Author: McHugh KM
Year: 2014
Journal: Pediatr Nephrol
Title: Megabladder mouse model of congenital obstructive nephropathy: genetic etiology and renal adaptation.
Volume: 29
Issue: 4
Pages: 645-50
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Publication
30015886 | J:294749
First Author: Xin G
Year: 2018
Journal: Mol Med Rep
Title: Candidate gene and mechanism investigations in congenital obstructive nephropathy based on bioinformatics analysis.
Volume: 18
Issue: 3
Pages: 2651-2660
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Publication
24023768 | J:207566
First Author: Becknell B
Year: 2013
Journal: PLoS One
Title: Molecular basis of renal adaptation in a murine model of congenital obstructive nephropathy.
Volume: 8
Issue: 9
Pages: e72762
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Publication
26401845 | J:292358
First Author: Becknell B
Year: 2015
Journal: PLoS One
Title: Urine Stasis Predisposes to Urinary Tract Infection by an Opportunistic Uropathogen in the Megabladder (Mgb) Mouse.
Volume: 10
Issue: 9
Pages: e0139077
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Genotype
Genotype
Symbol: mgb/mgb
Background: involves: C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: mgb/?
Background: involves: C57BL/6 * FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: mgb/mgb
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Myocd/Myocd<+>
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Publication
24275180 | J:211889
First Author: Kararigas G
Year: 2014
Journal: Mol Cell Endocrinol
Title: Estrogen modulates cardiac growth through an estrogen receptor α-dependent mechanism in healthy ovariectomized mice.
Volume: 382
Issue: 2
Pages: 909-14
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Publication
29183906 | J:257963
 
First Author: Sun X
Year: 2018
Journal: Biol Open
Title: Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function.
Volume: 7
Issue: 1
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Protein
Q8R2L3
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
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Publication
14565952 | -
First Author: Selvaraj A
Year: 2003
Journal: J Biol Chem
Title: Megakaryoblastic leukemia-1/2, a transcriptional co-activator of serum response factor, is required for skeletal myogenic differentiation.
Volume: 278
Issue: 43
Pages: 41977-87
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Protein Domain
IPR043451 | Myocardin-like
Type: Family
Description: Myocardin (Myocd) is a coactivator of serum response factor (SRF), which is a key regulator of the expression of smooth and cardiac muscle genes. Myocardin plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis) [, ]. It contains the RPEL repeats, which are monomeric globular actin (G-actin) binding elements. However, it binds to actin-related protein 5 (Arp5) instead of conventional actin, resulting in a significant suppression of Myocd activity [].Myocardin-related transcription factor A (MRTFA, also known MKL1) is an actin-binding transcriptional coactivator whose localisation is regulated by its interaction with monomeric actin (G-actin) []. Its N-terminal domain consists of three tandem RPEL repeats, where the G-actin binding site and the nuclear localisation signal can be found [, ]. In the nucleus MAL associates with SRF (serum response factor) and activates transcription of SRF:MAL-dependent target genes []. It has been implicated in human diseases, such as acute megakaryocytic leukemia []and other cancers [].MKL2 binds to and activates SRF (serum response factor) similar to myocardin and MKL1 [].This entry includes Myocardin and MKL/myocardin-like protein 1/2 (MKL1/2).
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Publication
22275180 | J:181270
First Author: Carpenter A
Year: 2012
Journal: Dev Dyn
Title: 3-Dimensional morphometric analysis of murine bladder development and dysmorphogenesis.
Volume: 241
Issue: 3
Pages: 522-33
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Publication
36424917 | J:340471
First Author: Warthi G
Year: 2022
Journal: Nat Cardiovasc Res
Title: Generation and Comparative Analysis of an Itga8-CreER (T2) Mouse with Preferential Activity in Vascular Smooth Muscle Cells.
Volume: 1
Issue: 11
Pages: 1084-1100
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Publication
27115886 | J:292562
First Author: Carpenter AR
Year: 2017
Journal: Pediatr Nephrol
Title: Role of renal urothelium in the development and progression of kidney disease.
Volume: 32
Issue: 4
Pages: 557-564
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Publication
27311482 | J:247205
First Author: Row S
Year: 2016
Journal: J Cell Sci
Title: Cadherin-11 is a novel regulator of extracellular matrix synthesis and tissue mechanics.
Volume: 129
Issue: 15
Pages: 2950-61
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Publication
29025710 | J:269229
First Author: Jin Y
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Opposing Actions of AKT (Protein Kinase B) Isoforms in Vascular Smooth Muscle Injury and Therapeutic Response.
Volume: 37
Issue: 12
Pages: 2311-2321
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Publication
24920580 | J:213570
First Author: Muraoka N
Year: 2014
Journal: EMBO J
Title: MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures.
Volume: 33
Issue: 14
Pages: 1565-81
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Publication
27521420 | J:236728
First Author: Chettimada S
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency.
Volume: 311
Issue: 4
Pages: H904-H912
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Publication
31461342 | J:282012
First Author: Swärd K
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Identification of the intermediate filament protein synemin/SYNM as a target of myocardin family coactivators.
Volume: 317
Issue: 6
Pages: C1128-C1142
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Publication
21545794 | J:173631
First Author: Zacharias WJ
Year: 2011
Journal: Dev Biol
Title: Hedgehog signaling controls homeostasis of adult intestinal smooth muscle.
Volume: 355
Issue: 1
Pages: 152-62
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Publication
36120506 | J:356584
First Author: Wu SP
Year: 2022
Journal: PNAS Nexus
Title: Myometrial progesterone receptor determines a transcription program for uterine remodeling and contractions during pregnancy.
Volume: 1
Issue: 4
Pages: pgac155
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Publication
28542204 | J:248524
First Author: Zhu B
Year: 2017
Journal: PLoS One
Title: Similar regulatory mechanisms of caveolins and cavins by myocardin family coactivators in arterial and bladder smooth muscle.
Volume: 12
Issue: 5
Pages: e0176759
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Publication
27105846 | J:246662
First Author: Wang Y
Year: 2016
Journal: Nucleic Acids Res
Title: ISL1 and JMJD3 synergistically control cardiac differentiation of embryonic stem cells.
Volume: 44
Issue: 14
Pages: 6741-55
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Publication
30026272 | J:285176
First Author: Hirai H
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Direct Reprogramming of Fibroblasts Into Smooth Muscle-Like Cells With Defined Transcription Factors-Brief Report.
Volume: 38
Issue: 9
Pages: 2191-2197
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Publication
21673315 | -
First Author: Mouilleron S
Year: 2011
Journal: Sci Signal
Title: Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator.
Volume: 4
Issue: 177
Pages: ra40
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Publication
21964294 | -
First Author: Hirano H
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL.
Volume: 414
Issue: 2
Pages: 373-8
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Publication
20818336 | J:165431
First Author: Pawłowski R
Year: 2010
Journal: EMBO J
Title: An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A.
Volume: 29
Issue: 20
Pages: 3448-58
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Publication
11344311 | -
First Author: Mercher T
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia.
Volume: 98
Issue: 10
Pages: 5776-9
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Publication
31055035 | J:274667
 
First Author: Madonna R
Year: 2019
Journal: J Mol Cell Cardiol
Title: Proteomic analysis of the secretome of adipose tissue-derived murine mesenchymal cells overexpressing telomerase and myocardin.
Volume: 131
Pages: 171-186
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Publication
19350017 | J:150313
First Author: Brandt DT
Year: 2009
Journal: Nat Cell Biol
Title: SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.
Volume: 11
Issue: 5
Pages: 557-68
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Protein
A0A668KL76
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Publication
29897287 | J:283631
First Author: Jackson AR
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: The uroplakin plaque promotes renal structural integrity during congenital and acquired urinary tract obstruction.
Volume: 315
Issue: 4
Pages: F1019-F1031
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Publication
34539433 | J:312497
 
First Author: Liu L
Year: 2021
Journal: Front Physiol
Title: Regulation of the Muscarinic M3 Receptor by Myocardin-Related Transcription Factors.
Volume: 12
Pages: 710968
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Publication
34671275 | J:312663
 
First Author: Liu L
Year: 2021
Journal: Front Physiol
Title: Cell Type Dependent Suppression of Inflammatory Mediators by Myocardin Related Transcription Factors.
Volume: 12
Pages: 732564
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Publication
37927241 | J:353636
First Author: Liu L
Year: 2023
Journal: Am J Physiol Cell Physiol
Title: Itga8-Cre-mediated deletion of YAP and TAZ impairs bladder contractility with minimal inflammation and chondrogenic differentiation.
Volume: 325
Issue: 6
Pages: C1485-C1501
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Publication
33416454 | J:304340
First Author: Dhagia V
Year: 2021
Journal: Am J Physiol Heart Circ Physiol
Title: G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases.
Volume: 320
Issue: 3
Pages: H999-H1016
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Protein
Q8K4J6
Organism: Mus musculus/domesticus
Length: 964  
Fragment?: false
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Protein
P59759
Organism: Mus musculus/domesticus
Length: 1080  
Fragment?: false
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Protein
A0A5F8MQ33
Organism: Mus musculus/domesticus
Length: 1029  
Fragment?: false
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Protein
Q5DTZ3
Organism: Mus musculus/domesticus
Length: 1080  
Fragment?: true
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Protein
G3X8R8
Organism: Mus musculus/domesticus
Length: 1091  
Fragment?: false
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Protein
Q3U1I6
Organism: Mus musculus/domesticus
Length: 964  
Fragment?: false
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Protein
A0A8D4USI8
Organism: Mus musculus/domesticus
Length: 1112  
Fragment?: false
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Protein
D3YUI2
Organism: Mus musculus/domesticus
Length: 979  
Fragment?: false
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Protein
D3YUG5
Organism: Mus musculus/domesticus
Length: 705  
Fragment?: true
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Protein
Q3U3V7
Organism: Mus musculus/domesticus
Length: 574  
Fragment?: true
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Protein
A3KMF2
Organism: Mus musculus/domesticus
Length: 1079  
Fragment?: true
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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