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Search results 401 to 453 out of 453 for Nampt

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0.028s

Type

Details

Score

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

•

Publication

30514106 | J:286576

First Author:	Sociali G
Year:	2019
Journal:	FASEB J
Title:	SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
Volume:	33
Issue:	3
Pages:	3704-3717

•

Publication

24347567 | J:206286

First Author:	Yang S
Year:	2015
Journal:	Ann Rheum Dis
Title:	NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.
Volume:	74
Issue:	3
Pages:	595-602

•

Publication

28408371 | J:262831

First Author:	Bermudez B
Year:	2017
Journal:	Arterioscler Thromb Vasc Biol
Title:	Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function.
Volume:	37
Issue:	6
Pages:	1157-1167

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Publication

37673371 | J:340834

First Author:	Han S
Year:	2023
Journal:	Neurosci Lett
Title:	Inhibition of neuronal Kv7 channels ameliorates MK-801-induced cognitive dysfunction in mice via up-regulating NAMPT expression.
Volume:	814

Pages:	137471

•

Publication

22190494 | J:179993

First Author:	Menssen A
Year:	2012
Journal:	Proc Natl Acad Sci U S A
Title:	The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.
Volume:	109
Issue:	4
Pages:	E187-96

•

Protein

Q99KQ4

Organism:	Mus musculus/domesticus
Length:	491
Fragment?:	false

•

Allele

Rr360<tm1Bcgen> | MGI:7435007

Name:	regulatory region 360; targeted mutation 1, Biocytogen LLC
Allele Type:	Targeted
Attribute String:	Conditional ready, Modified regulatory region

•

Allele

Col1a1<tm1(CAG-Nampt)Jbau> | MGI:5706806

Name:	collagen, type I, alpha 1; targeted mutation 1, Joseph A Baur
Allele Type:	Targeted
Attribute String:	Conditional ready, Inserted expressed sequence

•

Allele

Nampt<em1Smoc> | MGI:7291228

Name:	nicotinamide phosphoribosyltransferase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Conditional ready, No functional change

•

Publication

19819904 | -

First Author:	Takahashi R
Year:	2010
Journal:	J Biochem
Title:	Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase.
Volume:	147
Issue:	1
Pages:	95-107

•

Protein Domain

IPR041529 | DUF5598

Type:	Domain
Description:	This is the N-terminal domain found in Nicotinamide phosphoribosyltransferase (NAMPT) present in Homo sapiens. NAMPT captures nicotinamide (NAM) and replenishes the nicotinamide adenine dinucleotide (NAD+) pool during ADP-ribosylation and transferase reactions [].

•

Protein Domain

IPR016471 | Nicotinamide_PRibTrfase

Type:	Family
Description:	Nicotinamide phosphoribosyl transferase (NAMPT) catalyses the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD [, ]. NAMPT is also known as pre-B cell colony-enhancing factor (PBEF) or visfatin.

•

Strain

MGI:6475855 | C57BL/6JSmoc-Nampt<em1Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Publication

33771896 | J:312193

First Author:	Yoo KH
Year:	2021
Journal:	Cancer Res
Title:	Nicotinamide Mononucleotide Prevents Cisplatin-Induced Cognitive Impairments.
Volume:	81
Issue:	13
Pages:	3727-3737

•

HT Experiment

E-GEOD-74570 | Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle

Series Id:	GSE74570
Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	ArrayExpress

•

HT Experiment

GSE152067 | Adipocyte-specific inactivation of NAMPT, a key NAD+ biosynthetic enzyme, causes a metabolically-unhealthy lean phenotype in female mice during aging


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

•

Protein

Q3TLX1

Organism:	Mus musculus/domesticus
Length:	491
Fragment?:	false

•

Publication

19149599 | -

First Author:	Imai S
Year:	2009
Journal:	Curr Pharm Des
Title:	Nicotinamide phosphoribosyltransferase (Nampt): a link between NAD biology, metabolism, and diseases.
Volume:	15
Issue:	1
Pages:	20-8

•

Publication

19109034 | -

First Author:	Garten A
Year:	2009
Journal:	Trends Endocrinol Metab
Title:	Nampt: linking NAD biology, metabolism and cancer.
Volume:	20
Issue:	3
Pages:	130-8

•

Protein Domain

IPR041525 | N/Namide_PRibTrfase

Type:

Domain

Description:

Nicotinate phosphoribosyltransferase () is the rate-limiting enzyme that catalyses the first reaction in the NAD salvage synthesis []. Members in this family can be split into two further subfamilies represented in and . Members in have a different (longer) spacing of several key motifs and have an additional C-terminal domain of up to 100 residues. However, one argument suggesting that this family represents the same enzyme is that no species has a member of both subfamilies. Another is that the gene encoding this protein is located near other NAD salvage biosynthesis genes in Nostoc and in at least four different Gram-positive bacteria.Nicotinamide phosphoribosyl transferase (NAMPT) catalyses the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD [, ]. NAMPT is also known as pre-B cell colony-enhancing factor (PBEF) or visfatin.

•

Publication

25818290 | J:228171

First Author:	Gilley J
Year:	2015
Journal:	Cell Rep
Title:	Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
Volume:	10
Issue:	12
Pages:	1974-81

•

Publication

34290089 | J:320591

First Author:	Shi X
Year:	2021
Journal:	Sci Adv
Title:	Nuclear NAD⁺ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells.
Volume:	7
Issue:	30

•

Publication

35179955 | J:321691

First Author:	Quattrocelli M
Year:	2022
Journal:	Sci Adv
Title:	Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α.
Volume:	8
Issue:	7
Pages:	eabm1189

•

Publication

38092728 | J:347101

First Author:	Nomura M
Year:	2023
Journal:	Nat Commun
Title:	Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Volume:	14
Issue:	1
Pages:	8095

•

Publication

18490451 | -

First Author:	Boshoff HI
Year:	2008
Journal:	J Biol Chem
Title:	Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.
Volume:	283
Issue:	28
Pages:	19329-41

•

Publication

23750248 | J:203142

First Author:	Kennaway DJ
Year:	2013
Journal:	PLoS One
Title:	Global loss of bmal1 expression alters adipose tissue hormones, gene expression and glucose metabolism.
Volume:	8
Issue:	6
Pages:	e65255

•

Publication

32439965 | J:292058

First Author:	Locatelli M
Year:	2020
Journal:	Sci Rep
Title:	Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes.
Volume:	10
Issue:	1
Pages:	8418

•

Publication

21918578 | J:322727

First Author:	Kennaway DJ
Year:	2012
Journal:	Obesity (Silver Spring)
Title:	Adipokines and adipocyte function in Clock mutant mice that retain melatonin rhythmicity.
Volume:	20
Issue:	2
Pages:	295-305

•

Publication

24655393 | J:217239

First Author:	Ghosh D
Year:	2014
Journal:	Aging Cell
Title:	Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons.
Volume:	13
Issue:	4
Pages:	631-40

•

Publication

31003779 | J:291658

First Author:	Hoizumi M
Year:	2019
Journal:	Biochem Biophys Res Commun
Title:	Inhibition of GIP signaling extends lifespan without caloric restriction.
Volume:	513
Issue:	4
Pages:	974-982

•

Publication

21483791 | J:171657

First Author:	Um JH
Year:	2011
Journal:	PLoS One
Title:	AMPK regulates circadian rhythms in a tissue- and isoform-specific manner.
Volume:	6
Issue:	3
Pages:	e18450

•

Publication

25203735 | J:223418

First Author:	Hiragaki S
Year:	2014
Journal:	PLoS One
Title:	Melatonin signaling modulates clock genes expression in the mouse retina.
Volume:	9
Issue:	9
Pages:	e106819

•

Publication

37031230 | J:352454

First Author:	Park JW
Year:	2023
Journal:	Nat Commun
Title:	Circulating blood eNAMPT drives the circadian rhythms in locomotor activity and energy expenditure.
Volume:	14
Issue:	1
Pages:	1994

•

Publication

26982719 | J:232716

First Author:	Tran MT
Year:	2016
Journal:	Nature
Title:	PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.
Volume:	531
Issue:	7595
Pages:	528-32

•

Publication

27435822 | J:337573

First Author:	Morris-Blanco KC
Year:	2016
Journal:	Sci Rep
Title:	Protein Kinase C Epsilon Promotes Cerebral Ischemic Tolerance Via Modulation of Mitochondrial Sirt5.
Volume:	6

Pages:	29790

•

Publication

28752046 | J:321783

First Author:	Fletcher RS
Year:	2017
Journal:	Mol Metab
Title:	Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.
Volume:	6
Issue:	8
Pages:	819-832

•

Publication

29447131 | J:262881

First Author:	Touat M
Year:	2018
Journal:	J Clin Invest
Title:	DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.
Volume:	128
Issue:	4
Pages:	1671-1687

•

Publication

28254441 | J:250697

First Author:	Inoue T
Year:	2017
Journal:	Biochim Biophys Acta
Title:	Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways.
Volume:	1862
Issue:	5
Pages:	552-560

•

Publication

33051211 | J:300100

First Author:	Heer CD
Year:	2020
Journal:	J Biol Chem
Title:	Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity.
Volume:	295
Issue:	52
Pages:	17986-17996

•

Publication

23918774 | J:215852

First Author:	Brandauer J
Year:	2013
Journal:	J Physiol
Title:	AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle.
Volume:	591
Issue:	20
Pages:	5207-20

•

Publication

24905194 | J:218505

First Author:	Yamamoto T
Year:	2014
Journal:	PLoS One
Title:	Nicotinamide mononucleotide, an intermediate of NAD+ synthesis, protects the heart from ischemia and reperfusion.
Volume:	9
Issue:	6
Pages:	e98972

•

Publication

37457744 | J:338421

First Author:	Izadpanah A
Year:	2023
Journal:	Front Immunol
Title:	SARS-CoV-2 infection dysregulates NAD metabolism.
Volume:	14

Pages:	1158455

•

Publication

21478870 | J:171353

First Author:	Schoggins JW
Year:	2011
Journal:	Nature
Title:	A diverse range of gene products are effectors of the type I interferon antiviral response.
Volume:	472
Issue:	7344
Pages:	481-5

•

Publication

29146412 | J:263991

First Author:	Costford SR
Year:	2018
Journal:	Mol Metab
Title:	Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance.
Volume:	7

Pages:	1-11

•

Publication

30283350 | J:276044

First Author:	Deloux R
Year:	2018
Journal:	Front Physiol
Title:	Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training.
Volume:	9

Pages:	1290

•

Publication

29942262 | J:274996

First Author:	Brouwers B
Year:	2018
Journal:	Front Physiol
Title:	Elevated Nicotinamide Phosphoribosyl Transferase in Skeletal Muscle Augments Exercise Performance and Mitochondrial Respiratory Capacity Following Exercise Training.
Volume:	9

Pages:	704

•

Publication

34098144 | J:344992

First Author:	Spinelli S
Year:	2021
Journal:	Mol Metab
Title:	LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway.
Volume:	53

Pages:	101263

•

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