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Search results 401 to 450 out of 450 for Nampt

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Type

Details

Score

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

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Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

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Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

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Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

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Publication

30514106 | J:286576

First Author:	Sociali G
Year:	2019
Journal:	FASEB J
Title:	SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
Volume:	33
Issue:	3
Pages:	3704-3717

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Publication

24347567 | J:206286

First Author:	Yang S
Year:	2015
Journal:	Ann Rheum Dis
Title:	NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.
Volume:	74
Issue:	3
Pages:	595-602

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Publication

28408371 | J:262831

First Author:	Bermudez B
Year:	2017
Journal:	Arterioscler Thromb Vasc Biol
Title:	Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function.
Volume:	37
Issue:	6
Pages:	1157-1167

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Publication

37673371 | J:340834

First Author:	Han S
Year:	2023
Journal:	Neurosci Lett
Title:	Inhibition of neuronal Kv7 channels ameliorates MK-801-induced cognitive dysfunction in mice via up-regulating NAMPT expression.
Volume:	814

Pages:	137471

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Publication

22190494 | J:179993

First Author:	Menssen A
Year:	2012
Journal:	Proc Natl Acad Sci U S A
Title:	The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.
Volume:	109
Issue:	4
Pages:	E187-96

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Protein

Q99KQ4

Organism:	Mus musculus/domesticus
Length:	491
Fragment?:	false

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Allele

Rr360<tm1Bcgen> | MGI:7435007

Name:	regulatory region 360; targeted mutation 1, Biocytogen LLC
Allele Type:	Targeted
Attribute String:	Conditional ready, Modified regulatory region

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Allele

Col1a1<tm1(CAG-Nampt)Jbau> | MGI:5706806

Name:	collagen, type I, alpha 1; targeted mutation 1, Joseph A Baur
Allele Type:	Targeted
Attribute String:	Conditional ready, Inserted expressed sequence

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Allele

Nampt<em1Smoc> | MGI:7291228

Name:	nicotinamide phosphoribosyltransferase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Conditional ready, No functional change

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Publication

19819904 | -

First Author:	Takahashi R
Year:	2010
Journal:	J Biochem
Title:	Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase.
Volume:	147
Issue:	1
Pages:	95-107

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Protein Domain

IPR041529 | DUF5598

Type:	Domain
Description:	This is the N-terminal domain found in Nicotinamide phosphoribosyltransferase (NAMPT) present in Homo sapiens. NAMPT captures nicotinamide (NAM) and replenishes the nicotinamide adenine dinucleotide (NAD+) pool during ADP-ribosylation and transferase reactions [].

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Protein Domain

IPR016471 | Nicotinamide_PRibTrfase

Type:	Family
Description:	Nicotinamide phosphoribosyl transferase (NAMPT) catalyses the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD [, ]. NAMPT is also known as pre-B cell colony-enhancing factor (PBEF) or visfatin.

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Strain

MGI:6475855 | C57BL/6J-Nampt<em1Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

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Publication

33771896 | J:312193

First Author:	Yoo KH
Year:	2021
Journal:	Cancer Res
Title:	Nicotinamide Mononucleotide Prevents Cisplatin-Induced Cognitive Impairments.
Volume:	81
Issue:	13
Pages:	3727-3737

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HT Experiment

E-GEOD-74570 | Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle

Series Id:	GSE74570
Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	ArrayExpress

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Protein

Q3TLX1

Organism:	Mus musculus/domesticus
Length:	491
Fragment?:	false

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Publication

19149599 | -

First Author:	Imai S
Year:	2009
Journal:	Curr Pharm Des
Title:	Nicotinamide phosphoribosyltransferase (Nampt): a link between NAD biology, metabolism, and diseases.
Volume:	15
Issue:	1
Pages:	20-8

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Publication

19109034 | -

First Author:	Garten A
Year:	2009
Journal:	Trends Endocrinol Metab
Title:	Nampt: linking NAD biology, metabolism and cancer.
Volume:	20
Issue:	3
Pages:	130-8

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Protein Domain

IPR041525 | N/Namide_PRibTrfase

Type:

Domain

Description:

Nicotinate phosphoribosyltransferase () is the rate-limiting enzyme that catalyses the first reaction in the NAD salvage synthesis []. Members in this family can be split into two further subfamilies represented in and . Members in have a different (longer) spacing of several key motifs and have an additional C-terminal domain of up to 100 residues. However, one argument suggesting that this family represents the same enzyme is that no species has a member of both subfamilies. Another is that the gene encoding this protein is located near other NAD salvage biosynthesis genes in Nostoc and in at least four different Gram-positive bacteria.Nicotinamide phosphoribosyl transferase (NAMPT) catalyses the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD [, ]. NAMPT is also known as pre-B cell colony-enhancing factor (PBEF) or visfatin.

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Publication

25818290 | J:228171

First Author:	Gilley J
Year:	2015
Journal:	Cell Rep
Title:	Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
Volume:	10
Issue:	12
Pages:	1974-81

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Publication

35179955 | J:321691

First Author:	Quattrocelli M
Year:	2022
Journal:	Sci Adv
Title:	Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α.
Volume:	8
Issue:	7
Pages:	eabm1189

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Publication

34290089 | J:320591

First Author:	Shi X
Year:	2021
Journal:	Sci Adv
Title:	Nuclear NAD⁺ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells.
Volume:	7
Issue:	30

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Publication

38092728 | J:347101

First Author:	Nomura M
Year:	2023
Journal:	Nat Commun
Title:	Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Volume:	14
Issue:	1
Pages:	8095

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Publication

18490451 | -

First Author:	Boshoff HI
Year:	2008
Journal:	J Biol Chem
Title:	Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.
Volume:	283
Issue:	28
Pages:	19329-41

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Publication

23750248 | J:203142

First Author:	Kennaway DJ
Year:	2013
Journal:	PLoS One
Title:	Global loss of bmal1 expression alters adipose tissue hormones, gene expression and glucose metabolism.
Volume:	8
Issue:	6
Pages:	e65255

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Publication

21483791 | J:171657

First Author:	Um JH
Year:	2011
Journal:	PLoS One
Title:	AMPK regulates circadian rhythms in a tissue- and isoform-specific manner.
Volume:	6
Issue:	3
Pages:	e18450

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Publication

31003779 | J:291658

First Author:	Hoizumi M
Year:	2019
Journal:	Biochem Biophys Res Commun
Title:	Inhibition of GIP signaling extends lifespan without caloric restriction.
Volume:	513
Issue:	4
Pages:	974-982

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Publication

27435822 | J:337573

First Author:	Morris-Blanco KC
Year:	2016
Journal:	Sci Rep
Title:	Protein Kinase C Epsilon Promotes Cerebral Ischemic Tolerance Via Modulation of Mitochondrial Sirt5.
Volume:	6

Pages:	29790

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Publication

32439965 | J:292058

First Author:	Locatelli M
Year:	2020
Journal:	Sci Rep
Title:	Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes.
Volume:	10
Issue:	1
Pages:	8418

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Publication

26982719 | J:232716

First Author:	Tran MT
Year:	2016
Journal:	Nature
Title:	PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.
Volume:	531
Issue:	7595
Pages:	528-32

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Publication

24655393 | J:217239

First Author:	Ghosh D
Year:	2014
Journal:	Aging Cell
Title:	Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons.
Volume:	13
Issue:	4
Pages:	631-40

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Publication

25203735 | J:223418

First Author:	Hiragaki S
Year:	2014
Journal:	PLoS One
Title:	Melatonin signaling modulates clock genes expression in the mouse retina.
Volume:	9
Issue:	9
Pages:	e106819

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Publication

28752046 | J:321783

First Author:	Fletcher RS
Year:	2017
Journal:	Mol Metab
Title:	Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.
Volume:	6
Issue:	8
Pages:	819-832

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Publication

21918578 | J:322727

First Author:	Kennaway DJ
Year:	2012
Journal:	Obesity (Silver Spring)
Title:	Adipokines and adipocyte function in Clock mutant mice that retain melatonin rhythmicity.
Volume:	20
Issue:	2
Pages:	295-305

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Publication

29447131 | J:262881

First Author:	Touat M
Year:	2018
Journal:	J Clin Invest
Title:	DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.
Volume:	128
Issue:	4
Pages:	1671-1687

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Publication

28254441 | J:250697

First Author:	Inoue T
Year:	2017
Journal:	Biochim Biophys Acta
Title:	Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways.
Volume:	1862
Issue:	5
Pages:	552-560

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Publication

33051211 | J:300100

First Author:	Heer CD
Year:	2020
Journal:	J Biol Chem
Title:	Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity.
Volume:	295
Issue:	52
Pages:	17986-17996

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Publication

37457744 | J:338421

First Author:	Izadpanah A
Year:	2023
Journal:	Front Immunol
Title:	SARS-CoV-2 infection dysregulates NAD metabolism.
Volume:	14

Pages:	1158455

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Publication

24905194 | J:218505

First Author:	Yamamoto T
Year:	2014
Journal:	PLoS One
Title:	Nicotinamide mononucleotide, an intermediate of NAD+ synthesis, protects the heart from ischemia and reperfusion.
Volume:	9
Issue:	6
Pages:	e98972

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Publication

23918774 | J:215852

First Author:	Brandauer J
Year:	2013
Journal:	J Physiol
Title:	AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle.
Volume:	591
Issue:	20
Pages:	5207-20

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Publication

21478870 | J:171353

First Author:	Schoggins JW
Year:	2011
Journal:	Nature
Title:	A diverse range of gene products are effectors of the type I interferon antiviral response.
Volume:	472
Issue:	7344
Pages:	481-5

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Publication

29146412 | J:263991

First Author:	Costford SR
Year:	2018
Journal:	Mol Metab
Title:	Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance.
Volume:	7

Pages:	1-11

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Publication

30283350 | J:276044

First Author:	Deloux R
Year:	2018
Journal:	Front Physiol
Title:	Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training.
Volume:	9

Pages:	1290

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Publication

29942262 | J:274996

First Author:	Brouwers B
Year:	2018
Journal:	Front Physiol
Title:	Elevated Nicotinamide Phosphoribosyl Transferase in Skeletal Muscle Augments Exercise Performance and Mitochondrial Respiratory Capacity Following Exercise Training.
Volume:	9

Pages:	704

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Publication

34098144 | J:344992

First Author:	Spinelli S
Year:	2021
Journal:	Mol Metab
Title:	LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway.
Volume:	53

Pages:	101263

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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