|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 401 to 500 out of 634 for Nphs2

0.033s
Type Details Score
Publication
First Author: Ding M
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Regulation of hypoxia-inducible factor 2-a is essential for integrity of the glomerular barrier.
Volume: 304
Issue: 1
Pages: F120-6
Publication
First Author: Fukusumi Y
Year: 2018
Journal: J Am Soc Nephrol
Title: Nephrin-Binding Ephrin-B1 at the Slit Diaphragm Controls Podocyte Function through the JNK Pathway.
Volume: 29
Issue: 5
Pages: 1462-1474
Publication
First Author: Fukusumi Y
Year: 2021
Journal: Am J Pathol
Title: Nephrin-Ephrin-B1-Na+/H+ Exchanger Regulatory Factor 2-Ezrin-Actin Axis Is Critical in Podocyte Injury.
Volume: 191
Issue: 7
Pages: 1209-1226
Publication
First Author: Hong Q
Year: 2018
Journal: Kidney Int
Title: Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury.
Volume: 93
Issue: 6
Pages: 1330-1343
Publication
First Author: Wang L
Year: 2015
Journal: J Clin Invest
Title: Gq signaling causes glomerular injury by activating TRPC6.
Volume: 125
Issue: 5
Pages: 1913-26
Publication
First Author: Nijenhuis T
Year: 2011
Journal: Am J Pathol
Title: Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.
Volume: 179
Issue: 4
Pages: 1719-32
Allele
Name: nephrosis 2, podocin; targeted mutation 1.1, Paul T Brinkkoetter
Allele Type: Targeted
Attribute String: No functional change, Recombinase, Reporter
Publication
First Author: de Seigneux S
Year: 2015
Journal: J Am Soc Nephrol
Title: Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling.
Volume: 26
Issue: 7
Pages: 1608-18
Publication
First Author: Dizin E
Year: 2020
Journal: FASEB J
Title: Time-course of sodium transport along the nephron in nephrotic syndrome: The role of potassium.
Volume: 34
Issue: 2
Pages: 2408-2424
Publication
First Author: Faivre A
Year: 2021
Journal: Nephrol Dial Transplant
Title: Differential role of nicotinamide adenine dinucleotide deficiency in acute and chronic kidney disease.
Volume: 36
Issue: 1
Pages: 60-68
Publication
First Author: Baranwal G
Year: 2021
Journal: Physiol Rep
Title: Expanded renal lymphatics improve recovery following kidney injury.
Volume: 9
Issue: 22
Pages: e15094
Publication
First Author: Verissimo T
Year: 2022
Journal: J Am Soc Nephrol
Title: Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease.
Volume: 33
Issue: 4
Pages: 810-827
Genotype
Symbol: Tg(NPHS2-rtTA,tetO-cre)1Holt/?
Background: involves: C57BL/6 * FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Lama5/Lama5 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hprt1/? Tg(NPHS2-rtTA2*M2)1Jbk/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Jaml/Jaml Lepr/Lepr Tg(NPHS2-cre)295Lbh/?
Background: B6.Cg-Lepr Jaml Tg(NPHS2-cre)295Lbh
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Jaml/Jaml<+> Lepr/Lepr Tg(NPHS2-cre)295Lbh/?
Background: B6.Cg-Lepr Jaml Tg(NPHS2-cre)295Lbh
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(NPHS2-rtTA,tetO-cre)1Holt/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Miner JH
Year: 2002
Journal: J Clin Invest
Title: Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation.
Volume: 109
Issue: 8
Pages: 1065-72
Publication
First Author: Waters AM
Year: 2008
Journal: J Am Soc Nephrol
Title: Ectopic notch activation in developing podocytes causes glomerulosclerosis.
Volume: 19
Issue: 6
Pages: 1139-57
Publication
First Author: Okabe M
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Global polysome analysis of normal and injured podocytes.
Volume: 316
Issue: 2
Pages: F241-F252
Publication
First Author: Moeller MJ
Year: 2002
Journal: J Am Soc Nephrol
Title: Two gene fragments that direct podocyte-specific expression in transgenic mice.
Volume: 13
Issue: 6
Pages: 1561-7
Publication
First Author: Chittiprol S
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: Marker expression, behaviors, and responses vary in different lines of conditionally immortalized cultured podocytes.
Volume: 301
Issue: 3
Pages: F660-71
Publication
First Author: Guo J
Year: 2023
Journal: Cell Death Dis
Title: Long non-coding RNA DLX6-AS1 is the key mediator of glomerular podocyte injury and albuminuria in diabetic nephropathy by targeting the miR-346/GSK-3β signaling pathway.
Volume: 14
Issue: 2
Pages: 172
Publication
First Author: Majumder S
Year: 2019
Journal: Diabetologia
Title: Dysregulated expression but redundant function of the long non-coding RNA HOTAIR in diabetic kidney disease.
Volume: 62
Issue: 11
Pages: 2129-2142
Publication
First Author: Guzman J
Year: 2014
Journal: Diabetes
Title: Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy.
Volume: 63
Issue: 2
Pages: 701-14
Publication
First Author: Onions KL
Year: 2019
Journal: Diabetes
Title: VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy.
Volume: 68
Issue: 1
Pages: 172-187
Publication  
First Author: Veron D
Year: 2021
Journal: Front Pharmacol
Title: Podocyte VEGF-A Knockdown Induces Diffuse Glomerulosclerosis in Diabetic and in eNOS Knockout Mice.
Volume: 12
Pages: 788886
Publication
First Author: Kato H
Year: 2011
Journal: J Biol Chem
Title: Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival.
Volume: 286
Issue: 29
Pages: 26003-15
Publication
First Author: Delitsikou V
Year: 2020
Journal: FASEB J
Title: Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress.
Volume: 34
Issue: 2
Pages: 2087-2104
Publication
First Author: Shi Y
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Downregulation of PTEN promotes podocyte endocytosis of lipids aggravating obesity-related glomerulopathy.
Volume: 318
Issue: 3
Pages: F589-F599
Publication
First Author: Henique C
Year: 2016
Journal: J Am Soc Nephrol
Title: Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN.
Volume: 27
Issue: 1
Pages: 172-88
Publication  
First Author: Gee HY
Year: 2016
Journal: Nat Commun
Title: FAT1 mutations cause a glomerulotubular nephropathy.
Volume: 7
Pages: 10822
Publication
First Author: Guo JK
Year: 2013
Journal: Kidney Int
Title: The Terminator mouse is a diphtheria toxin-receptor knock-in mouse strain for rapid and efficient enrichment of desired cell lineages.
Volume: 84
Issue: 5
Pages: 1041-6
Publication
First Author: Chase SE
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Podocyte-specific knockout of myosin 1e disrupts glomerular filtration.
Volume: 303
Issue: 7
Pages: F1099-106
Publication  
First Author: Kunte SC
Year: 2023
Journal: Front Immunol
Title: No NLRP3 inflammasome activity in kidney epithelial cells, not even when the NLRP3-A350V Muckle-Wells variant is expressed in podocytes of diabetic mice.
Volume: 14
Pages: 1230050
Publication
First Author: Worthmann K
Year: 2013
Journal: Am J Pathol
Title: Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) λ/ι.
Volume: 183
Issue: 6
Pages: 1945-59
Publication
First Author: Ueda S
Year: 2021
Journal: Sci Rep
Title: TGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction.
Volume: 11
Issue: 1
Pages: 21643
Publication
First Author: Alquraishi M
Year: 2022
Journal: Cell Commun Signal
Title: Podocyte specific deletion of PKM2 ameliorates LPS-induced podocyte injury through beta-catenin.
Volume: 20
Issue: 1
Pages: 76
Publication
First Author: Tian X
Year: 2014
Journal: J Clin Invest
Title: Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.
Volume: 124
Issue: 3
Pages: 1098-113
Publication  
First Author: Ren J
Year: 2021
Journal: JCI Insight
Title: Twist1 in podocytes ameliorates podocyte injury and proteinuria by limiting CCL2-dependent macrophage infiltration.
Volume: 6
Issue: 15
Publication
First Author: Sweetwyne MT
Year: 2015
Journal: Diabetes
Title: Notch1 and Notch2 in Podocytes Play Differential Roles During Diabetic Nephropathy Development.
Volume: 64
Issue: 12
Pages: 4099-111
Publication
First Author: Veron D
Year: 2010
Journal: Kidney Int
Title: Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease.
Volume: 77
Issue: 11
Pages: 989-99
Publication
First Author: Oltean S
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: VEGF165b overexpression restores normal glomerular water permeability in VEGF164-overexpressing adult mice.
Volume: 303
Issue: 7
Pages: F1026-36
Publication
First Author: Chuang PY
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Reduction in podocyte SIRT1 accelerates kidney injury in aging mice.
Volume: 313
Issue: 3
Pages: F621-F628
Genotype
Symbol: Tcf3/Tcf3 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(NPHS2-icre/ERT2)1Dnsh/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Lama5/Lama5 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Vhl/Vhl Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S4/SvJae * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Myo1e/Myo1e Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nphs2/Nphs2<+>
Background: involves: C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Gao F
Year: 2004
Journal: Mol Cell Biol
Title: The Wt1+/R394W mouse displays glomerulosclerosis and early-onset renal failure characteristic of human Denys-Drash syndrome.
Volume: 24
Issue: 22
Pages: 9899-910
Publication
First Author: Lal MA
Year: 2015
Journal: J Am Soc Nephrol
Title: Rhophilin-1 is a key regulator of the podocyte cytoskeleton and is essential for glomerular filtration.
Volume: 26
Issue: 3
Pages: 647-62
Publication
First Author: Inoki K
Year: 2011
Journal: J Clin Invest
Title: mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
Volume: 121
Issue: 6
Pages: 2181-96
Publication
First Author: Li L
Year: 2021
Journal: Cell Rep
Title: PGC1α is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites.
Volume: 36
Issue: 6
Pages: 109510
Publication
First Author: Li L
Year: 2023
Journal: J Biol Chem
Title: The transcription factor ChREBP links mitochondrial lipidomes to mitochondrial morphology and progression of diabetic kidney disease.
Volume: 299
Issue: 9
Pages: 105185
Publication
First Author: Ayanga BA
Year: 2016
Journal: J Am Soc Nephrol
Title: Dynamin-Related Protein 1 Deficiency Improves Mitochondrial Fitness and Protects against Progression of Diabetic Nephropathy.
Volume: 27
Issue: 9
Pages: 2733-47
Publication
First Author: Kim JH
Year: 2021
Journal: Nat Commun
Title: Insulin-activated store-operated Ca2+ entry via Orai1 induces podocyte actin remodeling and causes proteinuria.
Volume: 12
Issue: 1
Pages: 6537
Publication
First Author: Manoharan J
Year: 2024
Journal: Immunity
Title: Tissue factor binds to and inhibits interferon-α receptor 1 signaling.
Volume: 57
Issue: 1
Pages: 68-85.e11
Publication
First Author: Hayashi K
Year: 2014
Journal: J Clin Invest
Title: KLF4-dependent epigenetic remodeling modulates podocyte phenotypes and attenuates proteinuria.
Volume: 124
Issue: 6
Pages: 2523-37
Publication
First Author: Liu R
Year: 2014
Journal: Diabetes
Title: Role of transcription factor acetylation in diabetic kidney disease.
Volume: 63
Issue: 7
Pages: 2440-53
Publication
First Author: Hahm E
Year: 2017
Journal: Nat Med
Title: Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Volume: 23
Issue: 1
Pages: 100-106
Publication
First Author: Reidy KJ
Year: 2009
Journal: Development
Title: Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development.
Volume: 136
Issue: 23
Pages: 3979-89
Publication
First Author: Qi W
Year: 2017
Journal: Nat Med
Title: Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction.
Volume: 23
Issue: 6
Pages: 753-762
Strain
Attribute String: congenic, targeted mutation, transgenic, mutant strain
Publication
First Author: Alghamdi TA
Year: 2017
Journal: J Am Soc Nephrol
Title: Janus Kinase 2 Regulates Transcription Factor EB Expression and Autophagy Completion in Glomerular Podocytes.
Volume: 28
Issue: 9
Pages: 2641-2653
Publication
First Author: Jia Q
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Ablation of developing podocytes disrupts cellular interactions and nephrogenesis both inside and outside the glomerulus.
Volume: 295
Issue: 6
Pages: F1790-8
Publication
First Author: Majumder S
Year: 2018
Journal: J Clin Invest
Title: Shifts in podocyte histone H3K27me3 regulate mouse and human glomerular disease.
Volume: 128
Issue: 1
Pages: 483-499
Publication
First Author: Möller-Hackbarth K
Year: 2021
Journal: Kidney Int
Title: Retinoic acid receptor responder1 promotes development of glomerular diseases via the Nuclear Factor-κB signaling pathway.
Volume: 100
Issue: 4
Pages: 809-823
Publication
First Author: Lin J
Year: 2015
Journal: J Pathol
Title: Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy.
Volume: 236
Issue: 1
Pages: 30-40
Publication
First Author: Gebeshuber CA
Year: 2013
Journal: Nat Med
Title: Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1.
Volume: 19
Issue: 4
Pages: 481-7
Publication
First Author: Hartleben B
Year: 2013
Journal: J Am Soc Nephrol
Title: aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation.
Volume: 24
Issue: 2
Pages: 253-67
Publication
First Author: Staffel J
Year: 2017
Journal: J Am Soc Nephrol
Title: Natriuretic Peptide Receptor Guanylyl Cyclase-A in Podocytes is Renoprotective but Dispensable for Physiologic Renal Function.
Volume: 28
Issue: 1
Pages: 260-277
Publication
First Author: Smeets B
Year: 2009
Journal: J Am Soc Nephrol
Title: Tracing the origin of glomerular extracapillary lesions from parietal epithelial cells.
Volume: 20
Issue: 12
Pages: 2604-15
Publication
First Author: Sun H
Year: 2022
Journal: Nat Commun
Title: Loss of CLDN5 in podocytes deregulates WIF1 to activate WNT signaling and contributes to kidney disease.
Volume: 13
Issue: 1
Pages: 1600
Publication
First Author: Wang Y
Year: 2010
Journal: J Am Soc Nephrol
Title: Activation of NFAT signaling in podocytes causes glomerulosclerosis.
Volume: 21
Issue: 10
Pages: 1657-66
Publication
First Author: Boehm M
Year: 2019
Journal: PLoS One
Title: A systems pharmacology workflow with experimental validation to assess the potential of anakinra for treatment of focal and segmental glomerulosclerosis.
Volume: 14
Issue: 3
Pages: e0214332
Publication
First Author: Francis M
Year: 2022
Journal: FASEB J
Title: SMPDL3b modulates radiation-induced DNA damage response in renal podocytes.
Volume: 36
Issue: 10
Pages: e22545
Publication
First Author: Ising C
Year: 2015
Journal: EMBO Mol Med
Title: Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure.
Volume: 7
Issue: 3
Pages: 275-87
Publication
First Author: Verma R
Year: 2018
Journal: PLoS One
Title: Nephrin is necessary for podocyte recovery following injury in an adult mature glomerulus.
Volume: 13
Issue: 6
Pages: e0198013
Publication  
First Author: Liu W
Year: 2021
Journal: Dis Model Mech
Title: Loss of phosphatidylserine flippase β-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis.
Volume: 14
Issue: 6
Publication
First Author: Guo JK
Year: 2012
Journal: J Am Soc Nephrol
Title: Increased tubular proliferation as an adaptive response to glomerular albuminuria.
Volume: 23
Issue: 3
Pages: 429-37
Publication
First Author: Zhdanova O
Year: 2011
Journal: Kidney Int
Title: The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy.
Volume: 80
Issue: 7
Pages: 719-30
Publication
First Author: Gödel M
Year: 2015
Journal: PLoS One
Title: Microtubule Associated Protein 1b (MAP1B) Is a Marker of the Microtubular Cytoskeleton in Podocytes but Is Not Essential for the Function of the Kidney Filtration Barrier in Mice.
Volume: 10
Issue: 10
Pages: e0140116
Publication
First Author: Sachs N
Year: 2006
Journal: J Cell Biol
Title: Kidney failure in mice lacking the tetraspanin CD151.
Volume: 175
Issue: 1
Pages: 33-9
Publication
First Author: Mallipattu SK
Year: 2015
Journal: J Clin Invest
Title: Krüppel-like factor 6 regulates mitochondrial function in the kidney.
Volume: 125
Issue: 3
Pages: 1347-61
Publication
First Author: Sheikh BN
Year: 2016
Journal: Oncogene
Title: MOF maintains transcriptional programs regulating cellular stress response.
Volume: 35
Issue: 21
Pages: 2698-710
Publication  
First Author: Puelles VG
Year: 2019
Journal: JCI Insight
Title: mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans.
Volume: 4
Issue: 18
Publication
First Author: Matsuura R
Year: 2020
Journal: Sci Rep
Title: SHROOM3, the gene associated with chronic kidney disease, affects the podocyte structure.
Volume: 10
Issue: 1
Pages: 21103
Publication
First Author: Johnstone DB
Year: 2013
Journal: PLoS One
Title: Background strain and the differential susceptibility of podocyte-specific deletion of Myh9 on murine models of experimental glomerulosclerosis and HIV nephropathy.
Volume: 8
Issue: 7
Pages: e67839
Publication
First Author: Niculovic KM
Year: 2019
Journal: J Am Soc Nephrol
Title: Podocyte-Specific Sialylation-Deficient Mice Serve as a Model for Human FSGS.
Volume: 30
Issue: 6
Pages: 1021-1035
Publication
First Author: Rinschen MM
Year: 2018
Journal: Cell Rep
Title: A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes.
Volume: 23
Issue: 8
Pages: 2495-2508
Publication
First Author: Arora S
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Human immunodeficiency virus downregulates podocyte apoE expression.
Volume: 297
Issue: 3
Pages: F653-61
Publication
First Author: Boerries M
Year: 2013
Journal: Kidney Int
Title: Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks.
Volume: 83
Issue: 6
Pages: 1052-64
Publication
First Author: Lin JS
Year: 2017
Journal: PLoS One
Title: ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics.
Volume: 12
Issue: 9
Pages: e0184575
Publication  
First Author: Rinschen MM
Year: 2017
Journal: Sci Signal
Title: YAP-mediated mechanotransduction determines the podocyte's response to damage.
Volume: 10
Issue: 474
Publication
First Author: Wu J
Year: 2015
Journal: J Clin Invest
Title: MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes.
Volume: 125
Issue: 11
Pages: 4091-106
Publication
First Author: Koehler S
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Par3A is dispensable for the function of the glomerular filtration barrier of the kidney.
Volume: 311
Issue: 1
Pages: F112-9
Publication
First Author: Kaverina NV
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Partial podocyte replenishment in experimental FSGS derives from nonpodocyte sources.
Volume: 310
Issue: 11
Pages: F1397-413
Publication
First Author: Juhila J
Year: 2006
Journal: J Am Soc Nephrol
Title: Podocyte cell-specific expression of doxycycline inducible Cre recombinase in mice.
Volume: 17
Issue: 3
Pages: 648-54