Type |
Details |
Score |
Publication |
First Author: |
Thaete LG |
Year: |
1991 |
Journal: |
Cancer Lett |
Title: |
Lung adenoma structure among inbred strains of mice: the pulmonary adenoma histologic type (Pah) genes. |
Volume: |
61 |
Issue: |
1 |
Pages: |
15-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato S |
Year: |
1998 |
Journal: |
Biol Pharm Bull |
Title: |
Response differences among mouse strains in DNA damage and skin carcinogenicity of 7,12-dimethylbenz[a]anthracene are due to inducible aryl hydrocarbon hydroxylase activity. |
Volume: |
21 |
Issue: |
1 |
Pages: |
90-2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berge G |
Year: |
2004 |
Journal: |
Br J Cancer |
Title: |
Analysis of resveratrol as a lung cancer chemopreventive agent in A/J mice exposed to benzo[a]pyrene. |
Volume: |
91 |
Issue: |
7 |
Pages: |
1380-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sutendra G |
Year: |
2014 |
Journal: |
Cell Metab |
Title: |
The metabolic basis of pulmonary arterial hypertension. |
Volume: |
19 |
Issue: |
4 |
Pages: |
558-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lai YC |
Year: |
2014 |
Journal: |
Circ Res |
Title: |
Pulmonary arterial hypertension: the clinical syndrome. |
Volume: |
115 |
Issue: |
1 |
Pages: |
115-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakayama J |
Year: |
2003 |
Journal: |
EMBO J |
Title: |
Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity. |
Volume: |
22 |
Issue: |
11 |
Pages: |
2776-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhagwani AR |
Year: |
2023 |
Journal: |
iScience |
Title: |
A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3. |
Volume: |
26 |
Issue: |
2 |
Pages: |
105935 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arnold ND |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension. |
Volume: |
10 |
Issue: |
1 |
Pages: |
5183 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar R |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension. |
Volume: |
8 |
|
Pages: |
15494 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo Y |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
CD146-HIF-1α hypoxic reprogramming drives vascular remodeling and pulmonary arterial hypertension. |
Volume: |
10 |
Issue: |
1 |
Pages: |
3551 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang GZ |
Year: |
2015 |
Journal: |
Elife |
Title: |
The chemokine CXCL13 in lung cancers associated with environmental polycyclic aromatic hydrocarbons pollution. |
Volume: |
4 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Liu D |
Year: |
2007 |
Journal: |
Blood |
Title: |
Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity. |
Volume: |
110 |
Issue: |
5 |
Pages: |
1502-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Calvier L |
Year: |
2017 |
Journal: |
Cell Metab |
Title: |
PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism. |
Volume: |
25 |
Issue: |
5 |
Pages: |
1118-1134.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li CG |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis. |
Volume: |
26 |
Issue: |
5 |
Pages: |
1333-1343.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ide F |
Year: |
2004 |
Journal: |
Cancer Lett |
Title: |
Skin and salivary gland carcinogenicity of 7,12-dimethylbenz[a]anthracene is equivalent in the presence or absence of aryl hydrocarbon receptor. |
Volume: |
214 |
Issue: |
1 |
Pages: |
35-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seki M |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension. |
Volume: |
14 |
Issue: |
8 |
Pages: |
e0220795 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diebold I |
Year: |
2015 |
Journal: |
Cell Metab |
Title: |
BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension. |
Volume: |
21 |
Issue: |
4 |
Pages: |
596-608 |
|
•
•
•
•
•
|
Publication |
First Author: |
Isobe S |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension. |
Volume: |
14 |
Issue: |
1 |
Pages: |
7578 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tamura Y |
Year: |
2018 |
Journal: |
J Clin Invest |
Title: |
Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension. |
Volume: |
128 |
Issue: |
5 |
Pages: |
1956-1970 |
|
•
•
•
•
•
|
Publication |
First Author: |
Modi BG |
Year: |
2012 |
Journal: |
Science |
Title: |
Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma. |
Volume: |
335 |
Issue: |
6064 |
Pages: |
104-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim JD |
Year: |
2023 |
Journal: |
J Biol Chem |
Title: |
Increased angiotensin II coupled with decreased Adra1a expression enhances cardiac hypertrophy in pregnancy-associated hypertensive mice. |
Volume: |
299 |
Issue: |
3 |
Pages: |
102964 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paulin R |
Year: |
2014 |
Journal: |
Cell Metab |
Title: |
Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans. |
Volume: |
20 |
Issue: |
5 |
Pages: |
827-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Syed M |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1173 |
|
•
•
•
•
•
|
Publication |
First Author: |
Threadgill DW |
Year: |
1990 |
Journal: |
Genomics |
Title: |
Syntenic conservation between humans and cattle. II. Human chromosome 12. |
Volume: |
8 |
Issue: |
1 |
Pages: |
29-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Race JE |
Year: |
1999 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). |
Volume: |
255 |
Issue: |
2 |
Pages: |
508-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hurst LA |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. |
Volume: |
8 |
|
Pages: |
14079 |
|
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•
•
•
•
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Publication |
First Author: |
Dai J |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway. |
Volume: |
9 |
Issue: |
1 |
Pages: |
3850 |
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•
•
•
•
|
Publication |
First Author: |
Sato S |
Year: |
1987 |
Journal: |
Mutat Res |
Title: |
Mouse strain differences in the induction of micronuclei by polycyclic aromatic hydrocarbons. |
Volume: |
192 |
Issue: |
3 |
Pages: |
185-9 |
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•
•
•
•
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Publication |
First Author: |
Morikawa M |
Year: |
2019 |
Journal: |
Sci Signal |
Title: |
The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension. |
Volume: |
12 |
Issue: |
607 |
|
|
•
•
•
•
•
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Publication |
First Author: |
Chu L |
Year: |
2021 |
Journal: |
Front Immunol |
Title: |
Perillaldehyde Inhibition of cGAS Reduces dsDNA-Induced Interferon Response. |
Volume: |
12 |
|
Pages: |
655637 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
232
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
45
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
171
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
174
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Csaki LS |
Year: |
2010 |
Journal: |
Annu Rev Nutr |
Title: |
Lipins: multifunctional lipid metabolism proteins. |
Volume: |
30 |
|
Pages: |
257-72 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
155
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
195
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
205
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
115
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
158
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
287
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Grenett HE |
Year: |
1987 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Full-length cDNA for rabbit tryptophan hydroxylase: functional domains and evolution of aromatic amino acid hydroxylases. |
Volume: |
84 |
Issue: |
16 |
Pages: |
5530-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fleischer TC |
Year: |
2003 |
Journal: |
Mol Cell Biol |
Title: |
Identification and characterization of three new components of the mSin3A corepressor complex. |
Volume: |
23 |
Issue: |
10 |
Pages: |
3456-67 |
|
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•
•
•
•
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Publication |
First Author: |
Sykes D |
Year: |
2004 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice. |
Volume: |
286 |
Issue: |
5 |
Pages: |
F972-8 |
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•
•
•
•
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Publication |
First Author: |
Tanaka K |
Year: |
2004 |
Journal: |
Biochem J |
Title: |
Cysteine residues in the organic anion transporter mOAT1. |
Volume: |
380 |
Issue: |
Pt 1 |
Pages: |
283-7 |
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•
•
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Publication |
First Author: |
Mair KM |
Year: |
2019 |
Journal: |
Eur Respir J |
Title: |
Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension. |
Volume: |
53 |
Issue: |
6 |
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•
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Publication |
First Author: |
Jamin EL |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Combined genotoxic effects of a polycyclic aromatic hydrocarbon (B(a)P) and an heterocyclic amine (PhIP) in relation to colorectal carcinogenesis. |
Volume: |
8 |
Issue: |
3 |
Pages: |
e58591 |
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•
•
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Publication |
First Author: |
Halberg RB |
Year: |
2008 |
Journal: |
Cancer Res |
Title: |
Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates. |
Volume: |
68 |
Issue: |
18 |
Pages: |
7394-402 |
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•
•
•
•
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Publication |
First Author: |
Hansmann G |
Year: |
2007 |
Journal: |
Circulation |
Title: |
Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation. |
Volume: |
115 |
Issue: |
10 |
Pages: |
1275-84 |
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•
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•
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Publication |
First Author: |
Hameed AG |
Year: |
2012 |
Journal: |
J Exp Med |
Title: |
Inhibition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension. |
Volume: |
209 |
Issue: |
11 |
Pages: |
1919-35 |
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•
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Publication |
First Author: |
Lawrie A |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Paigen diet-fed apolipoprotein E knockout mice develop severe pulmonary hypertension in an interleukin-1-dependent manner. |
Volume: |
179 |
Issue: |
4 |
Pages: |
1693-705 |
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Publication |
First Author: |
Hansmann G |
Year: |
2008 |
Journal: |
J Clin Invest |
Title: |
An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension. |
Volume: |
118 |
Issue: |
5 |
Pages: |
1846-57 |
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Publication |
First Author: |
Kwapiszewska G |
Year: |
2012 |
Journal: |
Am J Pathol |
Title: |
BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension. |
Volume: |
181 |
Issue: |
6 |
Pages: |
2018-29 |
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Publication |
First Author: |
Goten C |
Year: |
2023 |
Journal: |
Int J Mol Sci |
Title: |
Important Role of Endogenous Nerve Growth Factor Receptor in the Pathogenesis of Hypoxia-Induced Pulmonary Hypertension in Mice. |
Volume: |
24 |
Issue: |
3 |
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Publication |
First Author: |
Palmer LA |
Year: |
2007 |
Journal: |
J Clin Invest |
Title: |
S-nitrosothiols signal hypoxia-mimetic vascular pathology. |
Volume: |
117 |
Issue: |
9 |
Pages: |
2592-601 |
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Publication |
First Author: |
Zuckerbraun BS |
Year: |
2006 |
Journal: |
J Exp Med |
Title: |
Carbon monoxide reverses established pulmonary hypertension. |
Volume: |
203 |
Issue: |
9 |
Pages: |
2109-19 |
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•
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Publication |
First Author: |
Liu JQ |
Year: |
2006 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Hypoxic pulmonary hypertension: role of superoxide and NADPH oxidase (gp91phox). |
Volume: |
290 |
Issue: |
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Pages: |
L2-10 |
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Publication |
First Author: |
Haque MZ |
Year: |
2004 |
Journal: |
Hypertension |
Title: |
Assessment of renal functional phenotype in mice lacking gp91PHOX subunit of NAD(P)H oxidase. |
Volume: |
43 |
Issue: |
2 |
Pages: |
335-40 |
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Publication |
First Author: |
Larsen MC |
Year: |
2023 |
Journal: |
Int J Mol Sci |
Title: |
AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors. |
Volume: |
24 |
Issue: |
23 |
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First Author: |
Gastelum G |
Year: |
2020 |
Journal: |
Toxicol Sci |
Title: |
Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2. |
Volume: |
177 |
Issue: |
2 |
Pages: |
347-361 |
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First Author: |
Stading R |
Year: |
2024 |
Journal: |
Free Radic Biol Med |
Title: |
Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1. |
Volume: |
211 |
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35-46 |
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First Author: |
Kovacs L |
Year: |
2016 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Activation of Calpain-2 by Mediators in Pulmonary Vascular Remodeling of Pulmonary Arterial Hypertension. |
Volume: |
54 |
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3 |
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384-93 |
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First Author: |
Spiekerkoetter E |
Year: |
2013 |
Journal: |
J Clin Invest |
Title: |
FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension. |
Volume: |
123 |
Issue: |
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Pages: |
3600-13 |
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First Author: |
Launay JM |
Year: |
2012 |
Journal: |
Blood |
Title: |
Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension. |
Volume: |
119 |
Issue: |
7 |
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1772-80 |
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First Author: |
Borland MG |
Year: |
2014 |
Journal: |
Carcinogenesis |
Title: |
Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes. |
Volume: |
35 |
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1602-12 |
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First Author: |
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Year: |
2013 |
Journal: |
Cardiovasc Res |
Title: |
Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension. |
Volume: |
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Cancer Res |
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Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene. |
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Year: |
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Journal: |
Nat Med |
Title: |
Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension. |
Volume: |
21 |
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First Author: |
Long L |
Year: |
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Journal: |
Circ Res |
Title: |
Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice. |
Volume: |
98 |
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Publication |
First Author: |
Kugathasan L |
Year: |
2009 |
Journal: |
J Exp Med |
Title: |
The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice. |
Volume: |
206 |
Issue: |
10 |
Pages: |
2221-34 |
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Publication |
First Author: |
Kinoshita D |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Growth Factor Midkine Aggravates Pulmonary Arterial Hypertension via Surface Nucleolin. |
Volume: |
10 |
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1 |
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Publication |
First Author: |
Nie X |
Year: |
2018 |
Journal: |
J Mol Cell Cardiol |
Title: |
CCL5 deficiency rescues pulmonary vascular dysfunction, and reverses pulmonary hypertension via caveolin-1-dependent BMPR2 activation. |
Volume: |
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First Author: |
Schwappacher R |
Year: |
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Journal: |
J Biol Chem |
Title: |
A molecular mechanism for therapeutic effects of cGMP-elevating agents in pulmonary arterial hypertension. |
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First Author: |
Feltner M |
Year: |
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Journal: |
Toxics |
Title: |
Differential Susceptibility to Benzo[a]pyrene Exposure during Gestation and Lactation in Mice with Genetic Variations in the Aryl Hydrocarbon Receptor and Cyp1 Genes. |
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11 |
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