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Search results 401 to 500 out of 6883 for Pax6

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Type Details Score
Publication
18507827 | J:137605
 
First Author: Manuel M
Year: 2008
Journal: BMC Dev Biol
Title: Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance.
Volume: 8
Pages: 59
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Publication
29317485 | J:257543
First Author: Owa T
Year: 2018
Journal: J Neurosci
Title: Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation.
Volume: 38
Issue: 5
Pages: 1277-1294
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Publication
27452274 | J:258293
 
First Author: Divya TS
Year: 2016
Journal: Sci Rep
Title: Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrnα3 in Cerebellar Granule Neuron progenitors during development.
Volume: 6
Pages: 30337
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Publication
23622063 | J:197897
First Author: Mi D
Year: 2013
Journal: Neuron
Title: Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb.
Volume: 78
Issue: 2
Pages: 269-84
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Publication
24284204 | J:206312
First Author: Agoston Z
Year: 2014
Journal: Development
Title: Meis2 is a Pax6 co-factor in neurogenesis and dopaminergic periglomerular fate specification in the adult olfactory bulb.
Volume: 141
Issue: 1
Pages: 28-38
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Publication
25176648 | J:266003
First Author: Caballero IM
Year: 2014
Journal: Cell Rep
Title: Cell-autonomous repression of Shh by transcription factor Pax6 regulates diencephalic patterning by controlling the central diencephalic organizer.
Volume: 8
Issue: 5
Pages: 1405-18
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Publication
19500363 | J:151427
 
First Author: Simpson TI
Year: 2009
Journal: Neural Dev
Title: Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice.
Volume: 4
Pages: 19
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Publication
21698109 | J:174786
First Author: Jang ES
Year: 2011
Journal: PLoS One
Title: Pax6 expression is sufficient to induce a neurogenic fate in glial progenitors of the neonatal subventricular zone.
Volume: 6
Issue: 6
Pages: e20894
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Publication
29141678 | J:251853
First Author: Godbole G
Year: 2017
Journal: Neural Dev
Title: Novel functions of LHX2 and PAX6 in the developing telencephalon revealed upon combined loss of both genes.
Volume: 12
Issue: 1
Pages: 19
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Publication
21418559 | J:171704
 
First Author: Manuel MN
Year: 2011
Journal: Neural Dev
Title: The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels.
Volume: 6
Pages: 9
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Publication
17202185 | J:119936
First Author: Manuel M
Year: 2007
Journal: Development
Title: Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization.
Volume: 134
Issue: 3
Pages: 545-55
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Publication
12351726 | J:79212
First Author: Pratt T
Year: 2002
Journal: J Neurosci
Title: Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.
Volume: 22
Issue: 19
Pages: 8523-31
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Publication
16023139 | J:99977
First Author: Yang Y
Year: 2005
Journal: J Mol Biol
Title: Tissue-specific regulation of the mouse alphaA-crystallin gene in lens via recruitment of Pax6 and c-Maf to its promoter.
Volume: 351
Issue: 3
Pages: 453-69
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Publication
11481423 | J:71087
First Author: Collinson JM
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Primary defects in the lens underlie complex anterior segment abnormalities of the Pax6 heterozygous eye.
Volume: 98
Issue: 17
Pages: 9688-93
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Publication
15548580 | J:94457
First Author: Haubst N
Year: 2004
Journal: Development
Title: Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development.
Volume: 131
Issue: 24
Pages: 6131-40
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Publication
23933087 | J:201894
First Author: Ninkovic J
Year: 2013
Journal: Cell Stem Cell
Title: The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network.
Volume: 13
Issue: 4
Pages: 403-18
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Publication
23816521 | J:203015
First Author: Panayiotou E
Year: 2013
Journal: Gene Expr Patterns
Title: Pax6 is expressed in subsets of V0 and V2 interneurons in the ventral spinal cord in mice.
Volume: 13
Issue: 8
Pages: 328-34
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Protein
Q9JHQ8
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
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Publication
34534285 | J:312856
     
First Author: Dudek KD
Year: 2021
Journal: G3 (Bethesda)
Title: Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs.
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Publication
22031545 | J:178696
First Author: Asami M
Year: 2011
Journal: Development
Title: The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.
Volume: 138
Issue: 23
Pages: 5067-78
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Publication
24948600 | J:213871
First Author: Li X
Year: 2014
Journal: Development
Title: Sp8 plays a supplementary role to Pax6 in establishing the pMN/p3 domain boundary in the spinal cord.
Volume: 141
Issue: 14
Pages: 2875-84
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Publication
9006082 | J:38379
First Author: Xu PX
Year: 1997
Journal: Development
Title: Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode.
Volume: 124
Issue: 1
Pages: 219-31
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Publication
- | J:86523
     
First Author: Rossant J
Year: 2003
Journal: MGI Direct Data Submission
Title: A new allele at the Pax6 locus from the Center of Modeling Human Disease
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Publication
15917450 | J:98539
First Author: Kimura J
Year: 2005
Journal: J Neurosci
Title: Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium.
Volume: 25
Issue: 21
Pages: 5097-108
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Publication
21471366 | J:171187
First Author: Cocas LA
Year: 2011
Journal: J Neurosci
Title: Pax6 is required at the telencephalic pallial-subpallial boundary for the generation of neuronal diversity in the postnatal limbic system.
Volume: 31
Issue: 14
Pages: 5313-24
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Publication
12196586 | J:78745
First Author: Bishop KM
Year: 2002
Journal: J Neurosci
Title: Distinct actions of Emx1, Emx2, and Pax6 in regulating the specification of areas in the developing neocortex.
Volume: 22
Issue: 17
Pages: 7627-38
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Publication
24528677 | J:224508
 
First Author: Chatterjee M
Year: 2014
Journal: BMC Biol
Title: Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates.
Volume: 12
Pages: 13
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Publication
24065827 | J:202469
First Author: Robertshaw E
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Irx3 and Pax6 establish differential competence for Shh-mediated induction of GABAergic and glutamatergic neurons of the thalamus.
Volume: 110
Issue: 41
Pages: E3919-26
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Publication
11069887 | J:65765
First Author: Ashery-Padan R
Year: 2000
Journal: Genes Dev
Title: Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye.
Volume: 14
Issue: 21
Pages: 2701-11
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CL Term
CL:4042032 | PAX6 GABAergic cortical interneuron
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Publication
9828088 | J:50974
First Author: Sun T
Year: 1998
Journal: Mol Cell Neurosci
Title: Pax6 influences the time and site of origin of glial precursors in the ventral neural tube.
Volume: 12
Issue: 4-5
Pages: 228-39
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Publication
15376329 | J:93817
First Author: Faedo A
Year: 2004
Journal: Dev Dyn
Title: Identification and characterization of a novel transcript down-regulated in Dlx1/Dlx2 and up-regulated in Pax6 mutant telencephalon.
Volume: 231
Issue: 3
Pages: 614-20
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GXD Expression
GXD Expression
Probe: MGI:7578946
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7579009
Age: postnatal day 0
Image: 8A
Note: Pax6 is a pan-amacrine cell marker.
Specimen Label: 8A
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:2157328
Assay Type: Immunohistochemistry
Annotation Date: 2003-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691016
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:2676225
Age: embryonic day 10.0
Image: 1D,1F
Note: Slight gap between Pax6 and Nkx2.1 expression.
Specimen Label: 1D,1F
Detected: true
Specimen Num: 2
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Publication
23798316 | J:204473
First Author: Elso C
Year: 2013
Journal: Genesis
Title: A reciprocal translocation dissects roles of Pax6 alternative promoters and upstream regulatory elements in the development of pancreas, brain, and eye.
Volume: 51
Issue: 9
Pages: 630-46
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Publication
16303964 | J:103785
First Author: Graw J
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: Three novel Pax6 alleles in the mouse leading to the same small-eye phenotype caused by different consequences at target promoters.
Volume: 46
Issue: 12
Pages: 4671-83
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Publication
15878992 | J:99239
First Author: Kroll TT
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate.
Volume: 102
Issue: 20
Pages: 7374-9
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Publication
11731235 | J:73289
First Author: Estivill-Torrús G
Year: 2001
Journal: Mech Dev
Title: The transcription factor Pax6 is required for development of the diencephalic dorsal midline secretory radial glia that form the subcommissural organ.
Volume: 109
Issue: 2
Pages: 215-24
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Publication
32014531 | J:292981
 
First Author: Grant MK
Year: 2020
Journal: Brain Res
Title: Global and age-related neuroanatomical abnormalities in a Pax6-deficient mouse model of aniridia suggests a role for Pax6 in adult structural neuroplasticity.
Volume: 1732
Pages: 146698
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Publication
26485579 | J:231105
First Author: Ghosh M
Year: 2016
Journal: J Neurochem
Title: The transcription factor Pax6 contributes to the induction of GLT-1 expression in astrocytes through an interaction with a distal enhancer element.
Volume: 136
Issue: 2
Pages: 262-75
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Publication
27771509 | J:256746
First Author: Wang X
Year: 2017
Journal: Biochim Biophys Acta
Title: A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye.
Volume: 1863
Issue: 1
Pages: 60-67
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Publication
9232602 | J:41401
First Author: Grindley JC
Year: 1997
Journal: Mech Dev
Title: Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon.
Volume: 64
Issue: 1-2
Pages: 111-26
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Publication
11807037 | J:73778
First Author: Estivill-Torrus G
Year: 2002
Journal: Development
Title: Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors.
Volume: 129
Issue: 2
Pages: 455-66
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Publication
16979618 | J:119877
First Author: Quinn JC
Year: 2007
Journal: Dev Biol
Title: Pax6 controls cerebral cortical cell number by regulating exit from the cell cycle and specifies cortical cell identity by a cell autonomous mechanism.
Volume: 302
Issue: 1
Pages: 50-65
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Publication
11967891 | J:76341
First Author: Hevner RF
Year: 2002
Journal: J Comp Neurol
Title: Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other.
Volume: 447
Issue: 1
Pages: 8-17
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GXD Expression
GXD Expression
   
Probe: MGI:6180109
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191024
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pax6
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6180109
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191024
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pax6
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6180109
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191024
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pax6
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6180109
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191024
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pax6
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6180109
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191024
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pax6
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6180109
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191024
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pax6
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180109
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191024
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pax6
Detected: true
Specimen Num: 6
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Publication
23990468 | J:297319
First Author: Kogawa M
Year: 2013
Journal: J Biol Chem
Title: The paired-box homeodomain transcription factor Pax6 binds to the upstream region of the TRAP gene promoter and suppresses receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation.
Volume: 288
Issue: 43
Pages: 31299-312
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Publication
17064680 | J:119940
First Author: Blixt A
Year: 2007
Journal: Dev Biol
Title: Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage.
Volume: 302
Issue: 1
Pages: 218-29
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Publication
9883582 | J:51693
First Author: Grimm C
Year: 1998
Journal: Dev Genet
Title: Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern.
Volume: 23
Issue: 4
Pages: 299-316
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Publication
26520399 | J:226607
 
First Author: Clegg JM
Year: 2015
Journal: Neural Dev
Title: Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons.
Volume: 10
Pages: 26
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Publication
11731698 | J:74539
First Author: Jaskoll T
Year: 2002
Journal: Cells Tissues Organs
Title: Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice.
Volume: 170
Issue: 2-3
Pages: 83-98
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GXD Expression
GXD Expression
Probe: MGI:1346398
Assay Type: RNA in situ
Annotation Date: 1999-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1346419
Age: embryonic day 9.5
Image: 3K
Note: Pax6 is expressed in both the dorsal diencephalon and telencephalon.
Specimen Label: 3K
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2150299
Assay Type: RNA in situ
Annotation Date: 2001-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:2150342
Age: embryonic day 12.5
Note: Expression of mutated Pax6 transcript throughout the LGE.
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2150299
Assay Type: RNA in situ
Annotation Date: 2001-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:2150342
Age: embryonic day 16.5
Image: 7G
Note: Downregulation of the mutated Pax6 transcript in cortical VZ.
Specimen Label: 7G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:2157328
Assay Type: Immunohistochemistry
Annotation Date: 2003-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:2676225
Age: embryonic day 10.5
Image: 1G,1H,1I
Note: Gap in expression of Pax6 and Nkx2.1 expands.
Specimen Label: 1G,1H,1I
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2157328
Assay Type: Immunohistochemistry
Annotation Date: 2003-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:2676225
Age: embryonic day 9.5
Image: 3C
Note: Expression of Pax6 and Nkx2.1 form a distinct border.
Specimen Label: 3C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:1346398
Assay Type: RNA in situ
Annotation Date: 1999-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1346419
Age: embryonic day 9.5
Image: 3K
Note: Pax6 is expressed in both the dorsal diencephalon and telencephalon.
Specimen Label: 3K
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5440615
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-12-27
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6269401
Age: postnatal day 80
Note: EGFP expressions in testis substantially overlap with the Pax6 expressions.
Specimen Label: S4B
Detected: true
Specimen Num: 8
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Protein
Q8VHH9
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
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HT Experiment
E-GEOD-32271 | Pax6 mutant neocortex vs. wild type
Series Id: GSE32271
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
12419357 | -
First Author: Gorlov IP
Year: 2002
Journal: Anal Biochem
Title: A method for isolating alternatively spliced isoforms: isolation of murine Pax6 isoforms.
Volume: 308
Issue: 2
Pages: 401-4
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GXD Expression
GXD Expression
Probe: MGI:6287823
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293892
Age: embryonic day 13.5
Image: 2B
Note: No difference was noted in Pax6 expression level in the Sox9 cKO.
Specimen Label: 2B
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6287823
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Widespread
Stage: TS21
Assay Id: MGI:6293892
Age: embryonic day 13.5
Image: S1F
Note: In the early optic cup, Pax6 was detected throughout the retinal pigmented epithelium.
Specimen Label: S1F
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6287823
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-22
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1717228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6293892
Age: postnatal day 8
Image: S1I
Note: Pax6 was gradually replaced by Sox9 in the retinal pigmented epithelium.
Specimen Label: S1I
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6287823
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293892
Age: embryonic day 13.5
Image: S4D/E
Note: No difference was noted in Pax6 expression level in the Sox9 cKO.
Specimen Label: S4D/E
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1277653
Assay Type: RNA in situ
Annotation Date: 2023-02-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1758521
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7432885
Age: embryonic day 13.5
Note: Expressed in a region dorsal to a region of relatively low Pax6 expression.
Specimen Label: 5C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5440615
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6269401
Age: postnatal day 2
Note: Expressed in most cells. Pax6 and EGFP expressed at the similar levels.
Specimen Label: S4A
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1859757
Assay Type: Immunohistochemistry
Annotation Date: 2018-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6269407
Age: postnatal day 2
Note: Expressed in most cells. Pax6 and EGFP expressed at the similar levels.
Specimen Label: S4A
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2150299
Assay Type: RNA in situ
Annotation Date: 2001-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:2150342
Age: embryonic day 12.5
Image: 7A
Note: Expression of mutated Pax6 transcript at wild-type levels throughout the LGE.
Specimen Label: 7A
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2157328
Assay Type: Immunohistochemistry
Annotation Date: 2003-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:2676225
Age: embryonic day 9.5
Image: 1A,1C
Note: Expression of Pax6 and Nkx2.1 forms a boundary in the ventral telencephalon.
Specimen Label: 1A,1C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1859757
Assay Type: Immunohistochemistry
Annotation Date: 2018-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6269407
Age: postnatal day 2
Note: Expressed in most cells. Pax6 and EGFP expressed at the similar levels.
Specimen Label: S4A
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5440615
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-12-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6269401
Age: postnatal day 2
Note: Expressed in most cells. Pax6 and EGFP expressed at the similar levels.
Specimen Label: S4A
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1277653
Assay Type: RNA in situ
Annotation Date: 2001-08-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1608912
Stage: TS12
Assay Id: MGI:2148277
Age: embryonic day 8.0
Note: Authors state that Pax6 expression is not detected in double mutants at the 4-somite stage.
Specimen Label: not shown
Detected: false
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360666
Age: embryonic day 14.5
Image: 2H
Note: No Pax6 positive interneurons originated from the Olig2 lineage (p3/pMN/ventral-p2 domain).
Specimen Label: 2H
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360662
Age: embryonic day 14.5
Image: 5E
Note: In the mutant, the Pax6 positive interneurons were mostly co-expressing Vsx2. There were no Pax6-positive/Gata3-positive cells.
Specimen Label: 5E
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6360666
Age: postnatal day 25
Image: S1N
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true into adulthood.
Specimen Label: S1N
Detected: true
Specimen Num: 14
•
•
•
•
•
Publication
1687460 | J:1914
First Author: Walther C
Year: 1991
Journal: Development
Title: Pax-6, a murine paired box gene, is expressed in the developing CNS.
Volume: 113
Issue: 4
Pages: 1435-49
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6293889
Assay Type: RNA in situ
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293898
Age: embryonic day 13.5
Image: 1C Proximal Control
Note: There was a spatial dose-dependent inverse relationship between Pax6 and Sox9, with a significant negative correlation between the mRNA levels.
Specimen Label: 1C Proximal Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6293889
Assay Type: RNA in situ
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293898
Age: embryonic day 13.5
Image: 1C Middle Control
Note: There was a spatial dose-dependent inverse relationship between Pax6 and Sox9, with a significant negative correlation between the mRNA levels.
Specimen Label: 1C Middle Control
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6293889
Assay Type: RNA in situ
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293898
Age: embryonic day 13.5
Image: 1C Distal Control
Note: There was a spatial dose-dependent inverse relationship between Pax6 and Sox9, with a significant negative correlation between the mRNA levels.
Specimen Label: 1C Distal Control
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7524697
Assay Type: RNA in situ
Annotation Date: 2023-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7524726
Age: embryonic day 12.5
Image: 7J
Note: present / RR Domain expressing Lhx1, Isl1 and Pax6 but not Lhx5. Expression in putative ventral lateral geniculate nucleus.
Specimen Label: 7J
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2676483
Assay Type: RNA in situ
Annotation Date: 2003-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1690915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:2676607
Age: embryonic day 9.5
Image: 1J
Note: Marked decrease in size of expression domain in the forebrain. Gap between Pax6 and En1 domains is reduced.
Specimen Label: 1J
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2676483
Assay Type: RNA in situ
Annotation Date: 2003-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665715
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:2676607
Age: embryonic day 9.5
Image: 1J
Note: Marked decrease in size of expression domain in the forebrain. Gap between Pax6 and En1 domains is reduced.
Specimen Label: 1J
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6360666
Age: embryonic day 13.5
Image: S1B
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1B
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757725
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6360666
Age: embryonic day 17.5
Image: S1H
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1H
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6360666
Age: postnatal day 4
Image: S1K
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1K
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6356544
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6360666
Age: embryonic day 15.5
Image: S1E
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1E
Detected: true
Specimen Num: 11
•
•
•
•
•
Publication
12388550 | -
First Author: Mishra R
Year: 2002
Journal: J Biol Chem
Title: PAX6, paired domain influences sequence recognition by the homeodomain.
Volume: 277
Issue: 51
Pages: 49488-94
•
•
•
•
•
Protein
Q8VBX9
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: false
•
•
•
•
•
Publication
30894800 | J:276894
 
First Author: Dorà E
Year: 2019
Journal: Front Cell Neurosci
Title: Loss of Pax6 Causes Regional Changes in Dll1 Expression in Developing Cerebral Cortex.
Volume: 13
Pages: 78
•
•
•
•
•
Publication
28377501 | J:243672
First Author: Mitchell RK
Year: 2017
Journal: J Biol Chem
Title: The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice.
Volume: 292
Issue: 21
Pages: 8892-8906
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5910082
Assay Type: Immunohistochemistry
Annotation Date: 2018-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6159121
Age: embryonic day 13.5
Image: S2I
Note: Authors report compound mutant embryos had patterns of expression indistinguishable from those of Sox2 +/- or Pax6 Sey/+ single heterozygous mutants.
Specimen Label: S2I
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1928078
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1616617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7432600
Age: embryonic day 10.5
Note: Expressed in the p2 domain (gives rise to V2 interneurons), which was dorsal to the motor neuron progenitor domain (low Pax6 expression).
Specimen Label: 5C +/+ E10.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5910082
Assay Type: Immunohistochemistry
Annotation Date: 2018-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1667215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6159121
Age: embryonic day 9.5
Image: S2C
Note: Authors report compound mutant embryos had patterns of expression indistinguishable from those of Sox2 +/- or Pax6 Sey/+ single heterozygous mutants.
Specimen Label: S2C
Detected: true
Specimen Num: 9
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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