Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
144
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang DH |
Year: |
2006 |
Journal: |
Nucleic Acids Res |
Title: |
The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity. |
Volume: |
34 |
Issue: |
5 |
Pages: |
1393-404 |
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; wild type |
Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Moon J |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
PIF1 directly and indirectly regulates chlorophyll biosynthesis to optimize the greening process in Arabidopsis. |
Volume: |
105 |
Issue: |
27 |
Pages: |
9433-8 |
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; targeted mutation 1, Lea Harrington |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap OST212192, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap OST232504, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap OST273881, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap OST273882, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap OST292155, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap OST327745, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap H32B, H Earl Ruley |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap 31B, H Earl Ruley |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; targeted mutation 1, Velocigene |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou JQ |
Year: |
2002 |
Journal: |
Mol Biol Cell |
Title: |
Schizosaccharomyces pombe pfh1+ encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases. |
Volume: |
13 |
Issue: |
6 |
Pages: |
2180-91 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap E170G11, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap EUCE0231g09, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; targeted mutation 1e, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; targeted mutation 1a, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap IST13406D5, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap IST14455E10, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap IST14505F1, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap IST14601E7, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
PIF1 5'-to-3' DNA helicase; gene trap IST14998A6, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pif1/Pif1 |
Background: |
B6.129P2-Pif1 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pif1/Pif1 |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Pif1/Pif1<+> |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents a domain found in viral DNA replication helicases, bacterial ATP-dependent DNA helicase Pif1 and eukaryotic ATP-dependent DNA helicase PIF7. |
|
•
•
•
•
•
|
Publication |
First Author: |
Mateyak MK |
Year: |
2006 |
Journal: |
Cell Cycle |
Title: |
Human PIF helicase is cell cycle regulated and associates with telomerase. |
Volume: |
5 |
Issue: |
23 |
Pages: |
2796-804 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou J |
Year: |
2000 |
Journal: |
Science |
Title: |
Pif1p helicase, a catalytic inhibitor of telomerase in yeast. |
Volume: |
289 |
Issue: |
5480 |
Pages: |
771-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pinter SF |
Year: |
2008 |
Journal: |
Mol Cell Biol |
Title: |
The Schizosaccharomyces pombe Pfh1p DNA helicase is essential for the maintenance of nuclear and mitochondrial DNA. |
Volume: |
28 |
Issue: |
21 |
Pages: |
6594-608 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry includes a group of DNA helicases, including Pif1 and Rrm3 from budding yeasts and Pfh1 from fusion yeast. This entry also includes Pif1 like proteins from prokaryotes and eukaryotes including plants. Pif1 is a DNA helicase conserved from bacteria to humans [, ]. It suppresses both G-quadruplex-associated DNA damage and telomere lengthening. In budding yeast, it exists in two forms, nuclear form and mitochondrial form. Its nuclear form inhibits telomerase, while its mitochondrial form is involved in repair and recombination of mitochondrial DNA [, ]. In budding yeasts, another DNA replicative helicase, Rrm3 is recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses []. It shares protein sequence similarities with another DNA helicase, Pif1. However, their functions are different. Rrm3promotes telomere replication, while Pif1 inhibits telomere replication []. They also have opposite effects on replication fork progression in ribosomal DNA [].In fission yeasts, Pfh1 is required for the maintenance of both mitochondrial and nuclear genome stability [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Ivessa AS |
Year: |
2000 |
Journal: |
Cell |
Title: |
The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. |
Volume: |
100 |
Issue: |
4 |
Pages: |
479-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rajani S |
Year: |
2001 |
Journal: |
Curr Biol |
Title: |
The Arabidopsis myc/bHLH gene ALCATRAZ enables cell separation in fruit dehiscence. |
Volume: |
11 |
Issue: |
24 |
Pages: |
1914-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alvarez J |
Year: |
1999 |
Journal: |
Development |
Title: |
CRABS CLAW and SPATULA, two Arabidopsis genes that control carpel development in parallel with AGAMOUS. |
Volume: |
126 |
Issue: |
11 |
Pages: |
2377-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khanna R |
Year: |
2007 |
Journal: |
Plant Cell |
Title: |
The basic helix-loop-helix transcription factor PIF5 acts on ethylene biosynthesis and phytochrome signaling by distinct mechanisms. |
Volume: |
19 |
Issue: |
12 |
Pages: |
3915-29 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents ATP-dependent DNA helicase Rrm3 from buddingyeasts. It is a 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses []. It shares protein sequence similarities with another DNA helicase, Pif1. However, their functions are different. Rrm3 promotes telomere replication, while Pif1 inhibits telomere replication []. They also have opposite effects on replication fork progression in ribosomal DNA []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of plant helix-loop-helix (bHLH) transcription factors, including ALC, PIFs (phy-interacting factors) and SPATULA from Arabidopsis [, ]. ALC enables cell separation in fruit dehiscence, the processes in which the fruit opens and releases the seed []. PIF1 regulates chlorophyll biosynthesis to optimise the greening process []. PIF5 is involved in ethylene biosynthesis and phytochrome signalling []. SPATULA plays a role in floral organogenesis []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
398
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Toledo-Ortiz G |
Year: |
2003 |
Journal: |
Plant Cell |
Title: |
The Arabidopsis basic/helix-loop-helix transcription factor family. |
Volume: |
15 |
Issue: |
8 |
Pages: |
1749-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li X |
Year: |
2006 |
Journal: |
Plant Physiol |
Title: |
Genome-wide analysis of basic/helix-loop-helix transcription factor family in rice and Arabidopsis. |
Volume: |
141 |
Issue: |
4 |
Pages: |
1167-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qiao J |
Year: |
2011 |
Journal: |
Plant Cell Physiol |
Title: |
Two novel proteins, MRL7 and its paralog MRL7-L, have essential but functionally distinct roles in chloroplast development and are involved in plastid gene expression regulation in Arabidopsis. |
Volume: |
52 |
Issue: |
6 |
Pages: |
1017-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yua QB |
Year: |
2014 |
Journal: |
Mol Plant |
Title: |
AtECB1/MRL7, a thioredoxin-like fold protein with disulfide reductase activity, regulates chloroplast gene expression and chloroplast biogenesis in Arabidopsis thaliana. |
Volume: |
7 |
Issue: |
1 |
Pages: |
206-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu F |
Year: |
2011 |
Journal: |
Mol Plant |
Title: |
SUPPRESSOR OF VARIEGATION4, a new var2 suppressor locus, encodes a pioneer protein that is required for chloroplast biogenesis. |
Volume: |
4 |
Issue: |
2 |
Pages: |
229-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Powikrowska M |
Year: |
2014 |
Journal: |
Physiol Plant |
Title: |
SVR4 (suppressor of variegation 4) and SVR4-like: two proteins with a role in proper organization of the chloroplast genetic machinery. |
Volume: |
150 |
Issue: |
3 |
Pages: |
477-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang EJ |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches. |
Volume: |
10 |
Issue: |
1 |
Pages: |
2630 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This family represents a group of plant thioredoxin-like fold domain-containing proteins, including MRL7 (Protein MESOPHYLL-CELL RNAI LIBRARY LINE 7, also known as Protein EARLY CHLOROPLAST BIOGENESIS 1 (ECB1) or Protein SUPPRESSOR OF VARIEGATION 4 SVR4) and its paralog MRL7L from Arabidopsis. These proteins are required for early chloroplast development and involved in the regulation of plastid gene expression [, , , , ]. They also mediate the degradation of two repressors of chloroplast biogenesis, PIF1 and PIF3 in nucleus []. MRL7L is a necessary component of phytochrome signalling for photosynthesis-associated plastid-encoded genes (PhAPGs) activation []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Her J |
Year: |
2024 |
Journal: |
J Clin Invest |
Title: |
RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication. |
Volume: |
134 |
Issue: |
10 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Qiao J |
Year: |
2013 |
Journal: |
Plant Cell Physiol |
Title: |
PRDA1, a novel chloroplast nucleoid protein, is required for early chloroplast development and is involved in the regulation of plastid gene expression in Arabidopsis. |
Volume: |
54 |
Issue: |
12 |
Pages: |
2071-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
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