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Search results 401 to 500 out of 578 for Pink1

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Type Details Score
Publication
29036556 | J:268431
First Author: Kang C
Year: 2018
Journal: Cardiovasc Res
Title: Deficit in PINK1/PARKIN-mediated mitochondrial autophagy at late stages of dystrophic cardiomyopathy.
Volume: 114
Issue: 1
Pages: 90-102
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Publication
21839811 | J:184659
 
First Author: Madeo G
Year: 2012
Journal: Neuroscience
Title: Aberrant striatal synaptic plasticity in monogenic parkinsonisms.
Volume: 211
Pages: 126-35
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Publication
30449314 | J:272711
First Author: Abuaita BH
Year: 2018
Journal: Cell Host Microbe
Title: Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus.
Volume: 24
Issue: 5
Pages: 625-636.e5
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Publication
24615332 | J:210989
First Author: Melchor L
Year: 2014
Journal: J Pathol
Title: Identification of cellular and genetic drivers of breast cancer heterogeneity in genetically engineered mouse tumour models.
Volume: 233
Issue: 2
Pages: 124-37
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Publication
35411325 | J:351587
First Author: Ma X
Year: 2022
Journal: JACC Basic Transl Sci
Title: TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis.
Volume: 7
Issue: 3
Pages: 223-243
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Publication
32080200 | J:286397
First Author: Luciani A
Year: 2020
Journal: Nat Commun
Title: Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency.
Volume: 11
Issue: 1
Pages: 970
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Publication
31536960 | J:282679
 
First Author: Moutaoufik MT
Year: 2019
Journal: iScience
Title: Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Volume: 19
Pages: 1114-1132
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Publication
37319285 | J:346282
First Author: Kinsella RL
Year: 2023
Journal: PLoS Biol
Title: Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophages.
Volume: 21
Issue: 6
Pages: e3002159
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Publication
30305733 | J:267715
First Author: Wiwatpanit T
Year: 2018
Journal: Nature
Title: Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1.
Volume: 563
Issue: 7733
Pages: 691-695
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Publication
36754021 | J:333326
First Author: Suh J
Year: 2023
Journal: Cell Metab
Title: Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis.
Volume: 35
Issue: 2
Pages: 345-360.e7
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Publication
28465321 | J:356661
First Author: Esteban-Martínez L
Year: 2017
Journal: EMBO J
Title: Programmed mitophagy is essential for the glycolytic switch during cell differentiation.
Volume: 36
Issue: 12
Pages: 1688-1706
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HT Experiment
GSE232119 | Analysis of gene expression of mice's thyroid glands according to the state of the Pink1 Knock-out
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
- | J:169366
     
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
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Publication
23341629 | J:193822
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 622
Description: Phosphoserine; by PINK1
Type: modified residue
End: 622
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UniProt Feature
UniProt Feature
Begin: 111
Description: Phosphothreonine; by PINK1
Type: modified residue
End: 111
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UniProt Feature
UniProt Feature
Begin: 250
Description: Phosphoserine; by PINK1
Type: modified residue
End: 250
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UniProt Feature
UniProt Feature
Begin: 65
Description: Phosphoserine; by PINK1
Type: modified residue
End: 65
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UniProt Feature
UniProt Feature
Begin: 65
Description: Phosphoserine; by PINK1
Type: modified residue
End: 65
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UniProt Feature
UniProt Feature
Begin: 174
Description: Phosphothreonine; by PINK1
Type: modified residue
End: 174
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UniProt Feature
UniProt Feature
Begin: 65
Description: Phosphoserine; by PINK1
Type: modified residue
End: 65
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UniProt Feature
UniProt Feature
Begin: 65
Description: Phosphoserine; by PINK1
Type: modified residue
End: 65
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UniProt Feature
UniProt Feature
Begin: 65
Description: Phosphoserine; by PINK1
Type: modified residue
End: 65
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HT Sample
GE1_P12 (1_1) PINK1 KO
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal month 6
Stage: 28
Structure . Name: cerebral cortex
Curation Status: Curated
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HT Sample
GE1_P13 (2_2) PINK1 KO
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal month 6
Stage: 28
Structure . Name: cerebral cortex
Curation Status: Curated
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HT Sample
GE1_P16 (2_3) PINK1 KO
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal month 6
Stage: 28
Structure . Name: cerebral cortex
Curation Status: Curated
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HT Sample
GE1_P18 (1_4) PINK1 KO
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal month 6
Stage: 28
Structure . Name: cerebral cortex
Curation Status: Curated
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HT Sample
miRNA_P12 (1_1) PINK1 KO
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal month 6
Stage: 28
Structure . Name: cerebral cortex
Curation Status: Curated
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HT Sample
miRNA_P13 (2_2) PINK1 KO
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal month 6
Stage: 28
Structure . Name: cerebral cortex
Curation Status: Curated
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HT Sample
miRNA_P16 (2_3) PINK1 KO
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal month 6
Stage: 28
Structure . Name: cerebral cortex
Curation Status: Curated
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HT Sample
miRNA_P18 (1_4) PINK1 KO
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal month 6
Stage: 28
Structure . Name: cerebral cortex
Curation Status: Curated
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Publication
21426348 | J:212792
First Author: Meissner C
Year: 2011
Journal: J Neurochem
Title: The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking.
Volume: 117
Issue: 5
Pages: 856-67
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Publication
21138942 | J:212795
First Author: Deas E
Year: 2011
Journal: Hum Mol Genet
Title: PINK1 cleavage at position A103 by the mitochondrial protease PARL.
Volume: 20
Issue: 5
Pages: 867-79
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Publication
21115803 | J:166967
First Author: Jin SM
Year: 2010
Journal: J Cell Biol
Title: Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.
Volume: 191
Issue: 5
Pages: 933-42
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HT Experiment
E-GEOD-60414 | Potentiation of neurotoxicity in double mutant mice with Pink1 ablation and A53T-SNCA overexpression
Series Id: GSE60414
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
35353626 | J:329258
First Author: Nagpal L
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Inositol hexakisphosphate kinase-2 non-catalytically regulates mitophagy by attenuating PINK1 signaling.
Volume: 119
Issue: 14
Pages: e2121946119
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Publication
27423393 | J:238665
First Author: Cang X
Year: 2016
Journal: Biochem Biophys Res Commun
Title: PINK1 alleviates palmitate induced insulin resistance in HepG2 cells by suppressing ROS mediated MAPK pathways.
Volume: 478
Issue: 1
Pages: 431-438
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Publication
20457924 | J:160541
First Author: Hao LY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function.
Volume: 107
Issue: 21
Pages: 9747-52
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Publication
27325644 | J:234923
First Author: Agnihotri S
Year: 2016
Journal: Cancer Res
Title: PINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma.
Volume: 76
Issue: 16
Pages: 4708-19
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Publication
22582012 | J:184762
First Author: Vos M
Year: 2012
Journal: Science
Title: Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.
Volume: 336
Issue: 6086
Pages: 1306-10
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Publication
22910362 | -
 
First Author: Okatsu K
Year: 2012
Journal: Nat Commun
Title: PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria.
Volume: 3
Pages: 1016
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Publication
25345844 | -
First Author: Kazlauskaite A
Year: 2015
Journal: FEBS J
Title: PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease.
Volume: 282
Issue: 2
Pages: 215-23
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Publication
22078885 | -
First Author: Wang X
Year: 2011
Journal: Cell
Title: PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility.
Volume: 147
Issue: 4
Pages: 893-906
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Allele
Pink1<tm1Shn> | MGI:3716083
Name: PTEN induced putative kinase 1; targeted mutation 1, Jie Shen
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Pink1<tm1Aub> | MGI:3850370
Name: PTEN induced putative kinase 1; targeted mutation 1, Georg Auburger
Allele Type: Targeted
Attribute String: Humanized sequence, Null/knockout
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Allele
Pink1<tm1Hbu> | MGI:4941901
Name: PTEN induced putative kinase 1; targeted mutation 1, Hansruedi Bueler
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Pink1<tm1.1Wrst> | MGI:5436308
Name: PTEN induced putative kinase 1; targeted mutation 1.1, Wolfgang Wurst
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
32140098 | J:313126
 
First Author: Huang Z
Year: 2020
Journal: Front Cell Neurosci
Title: Depletion of LncRNA NEAT1 Rescues Mitochondrial Dysfunction Through NEDD4L-Dependent PINK1 Degradation in Animal Models of Alzheimer's Disease.
Volume: 14
Pages: 28
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Interaction Experiment
Kim KH (2010)
Description: PINK1 gene knockdown leads to increased binding of parkin with actin filament.
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Interaction Experiment
Chen BB (2014)
Description: E3 Ligase Subunit Fbxo15 and PINK1 Kinase Regulate Cardiolipin Synthase 1 Stability and Mitochondrial Function in Pneumonia.
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Genotype
Genotype
Symbol: Pink1/Pink1
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pink1/Pink1
Background: involves: 129S/SvEv
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pink1/Pink1
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pink1/Pink1
Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0060369 | Parkinson's disease 6
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Publication
25474007 | -
First Author: Shiba-Fukushima K
Year: 2014
Journal: PLoS Genet
Title: Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering.
Volume: 10
Issue: 12
Pages: e1004861
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Publication
19909785 | -
First Author: Kim KH
Year: 2010
Journal: Neurosci Lett
Title: PINK1 gene knockdown leads to increased binding of parkin with actin filament.
Volume: 468
Issue: 3
Pages: 272-6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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