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Search results 401 to 500 out of 693 for Pkd2

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Type Details Score
Publication
First Author: Sohara E
Year: 2008
Journal: J Am Soc Nephrol
Title: Nek8 regulates the expression and localization of polycystin-1 and polycystin-2.
Volume: 19
Issue: 3
Pages: 469-76
Publication
First Author: Rezaie T
Year: 2005
Journal: Genomics
Title: Molecular cloning, genomic structure, and protein characterization of mouse optineurin.
Volume: 85
Issue: 1
Pages: 131-8
Publication
First Author: Arhatte M
Year: 2019
Journal: Nat Commun
Title: TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells.
Volume: 10
Issue: 1
Pages: 2024
Publication
First Author: Peyronnet R
Year: 2013
Journal: EMBO Rep
Title: Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells.
Volume: 14
Issue: 12
Pages: 1143-8
Publication
First Author: Doctor RB
Year: 2007
Journal: Biochim Biophys Acta
Title: Regulated ion transport in mouse liver cyst epithelial cells.
Volume: 1772
Issue: 3
Pages: 345-54
Publication
First Author: Amura CR
Year: 2008
Journal: Am J Physiol Cell Physiol
Title: CXCR2 agonists in ADPKD liver cyst fluids promote cell proliferation.
Volume: 294
Issue: 3
Pages: C786-96
Publication
First Author: Wang X
Year: 2017
Journal: PLoS One
Title: Generation and phenotypic characterization of Pde1a mutant mice.
Volume: 12
Issue: 7
Pages: e0181087
Publication
First Author: Pazour GJ
Year: 2002
Journal: Curr Biol
Title: Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease.
Volume: 12
Issue: 11
Pages: R378-80
Publication
First Author: Geng L
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.
Volume: 105
Issue: 41
Pages: 15920-5
Publication
First Author: Kleene SJ
Year: 2019
Journal: PLoS One
Title: The TRPP2-dependent channel of renal primary cilia also requires TRPM3.
Volume: 14
Issue: 3
Pages: e0214053
Publication
First Author: Lehtonen S
Year: 2000
Journal: J Biol Chem
Title: In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2.
Volume: 275
Issue: 42
Pages: 32888-93
Publication
First Author: Hopp K
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Effects of hydration in rats and mice with polycystic kidney disease.
Volume: 308
Issue: 3
Pages: F261-6
Publication
First Author: Masyuk AI
Year: 2010
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia.
Volume: 299
Issue: 4
Pages: G990-9
Publication
First Author: Warner G
Year: 2016
Journal: J Am Soc Nephrol
Title: Food Restriction Ameliorates the Development of Polycystic Kidney Disease.
Volume: 27
Issue: 5
Pages: 1437-47
Publication
First Author: Allen E
Year: 2006
Journal: Hum Mol Genet
Title: Loss of polycystin-1 or polycystin-2 results in dysregulated apolipoprotein expression in murine tissues via alterations in nuclear hormone receptors.
Volume: 15
Issue: 1
Pages: 11-21
Publication
First Author: Anyatonwu GI
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2.
Volume: 104
Issue: 15
Pages: 6454-9
Publication
First Author: Boulter C
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene.
Volume: 98
Issue: 21
Pages: 12174-9
Publication
First Author: Nikonova AS
Year: 2018
Journal: FASEB J
Title: Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD).
Volume: 32
Issue: 5
Pages: 2735-2746
Publication
First Author: Cai Y
Year: 2014
Journal: J Clin Invest
Title: Altered trafficking and stability of polycystins underlie polycystic kidney disease.
Volume: 124
Issue: 12
Pages: 5129-44
Publication
First Author: Chang E
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Restoring multidrug resistance-associated protein 3 attenuates cell proliferation in the polycystic kidney.
Volume: 308
Issue: 9
Pages: F1004-11
Publication    
First Author: MacKay CE
Year: 2022
Journal: Elife
Title: A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation.
Volume: 11
Publication
First Author: Woo YM
Year: 2017
Journal: Sci Rep
Title: Profiling of miRNAs and target genes related to cystogenesis in ADPKD mouse models.
Volume: 7
Issue: 1
Pages: 14151
Publication  
First Author: Kuo IY
Year: 2019
Journal: Sci Signal
Title: Polycystin 2 regulates mitochondrial Ca2+ signaling, bioenergetics, and dynamics through mitofusin 2.
Volume: 12
Issue: 580
Publication
First Author: Newby LJ
Year: 2002
Journal: J Biol Chem
Title: Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex.
Volume: 277
Issue: 23
Pages: 20763-73
Publication
First Author: Ong AC
Year: 1999
Journal: Nephrol Dial Transplant
Title: Cyst formation in ADPKD: new insights from natural and targeted mutants.
Volume: 14
Issue: 3
Pages: 544-6
Publication
First Author: Boletta A
Year: 2003
Journal: Trends Cell Biol
Title: Role of polycystins in renal tubulogenesis.
Volume: 13
Issue: 9
Pages: 484-92
Publication
First Author: Wang S
Year: 2007
Journal: Mol Cell Biol
Title: Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.
Volume: 27
Issue: 8
Pages: 3241-52
Publication
First Author: Kaja S
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Polycystin-2 expression and function in adult mouse lacrimal acinar cells.
Volume: 52
Issue: 8
Pages: 5605-11
Publication
First Author: Choi YH
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.
Volume: 108
Issue: 26
Pages: 10679-84
Publication
First Author: Follit JA
Year: 2006
Journal: Mol Biol Cell
Title: The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly.
Volume: 17
Issue: 9
Pages: 3781-92
Publication
First Author: Outeda P
Year: 2017
Journal: Kidney Int
Title: A novel model of autosomal recessive polycystic kidney questions the role of the fibrocystin C-terminus in disease mechanism.
Volume: 92
Issue: 5
Pages: 1130-1144
Publication
First Author: Nauli SM
Year: 2003
Journal: Nat Genet
Title: Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells.
Volume: 33
Issue: 2
Pages: 129-37
Publication
First Author: Monirujjaman M
Year: 2017
Journal: Biochim Biophys Acta
Title: Distinct oxylipin alterations in diverse models of cystic kidney diseases.
Volume: 1862
Issue: 12
Pages: 1562-1574
Publication
First Author: Manning DK
Year: 2013
Journal: J Am Soc Nephrol
Title: Loss of the ciliary kinase Nek8 causes left-right asymmetry defects.
Volume: 24
Issue: 1
Pages: 100-12
Publication
First Author: Amura CR
Year: 2007
Journal: Am J Physiol Cell Physiol
Title: VEGF receptor inhibition blocks liver cyst growth in pkd2(WS25/-) mice.
Volume: 293
Issue: 1
Pages: C419-28
Publication
First Author: Ghosh Roy S
Year: 2023
Journal: J Am Soc Nephrol
Title: Dnajb11 -Kidney supDevelops from Reduced Polycystin-1 Dosage but not Unfolded Protein Response in Mice.
Volume: 34
Issue: 9
Pages: 1521-1534
Publication
First Author: Masyuk TV
Year: 2014
Journal: Am J Pathol
Title: Centrosomal abnormalities characterize human and rodent cystic cholangiocytes and are associated with Cdc25A overexpression.
Volume: 184
Issue: 1
Pages: 110-21
Publication
First Author: Li X
Year: 2008
Journal: Nat Med
Title: A tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney disease.
Volume: 14
Issue: 8
Pages: 863-8
Publication
First Author: McGrath J
Year: 2003
Journal: Cell
Title: Two populations of node monocilia initiate left-right asymmetry in the mouse.
Volume: 114
Issue: 1
Pages: 61-73
Publication
First Author: Aboualaiwi WA
Year: 2014
Journal: Circulation
Title: Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation.
Volume: 129
Issue: 6
Pages: 660-72
Publication
First Author: Yoder BK
Year: 2002
Journal: J Am Soc Nephrol
Title: The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia.
Volume: 13
Issue: 10
Pages: 2508-16
Publication
First Author: Liu M
Year: 2018
Journal: Shock
Title: Primary Cilia Deficiency Induces Intracranial Aneurysm.
Volume: 49
Issue: 5
Pages: 604-611
Publication
First Author: Rah G
Year: 2022
Journal: J Am Soc Nephrol
Title: KLC3 Regulates Ciliary Trafficking and Cyst Progression in CILK1 Deficiency-Related Polycystic Kidney Disease.
Volume: 33
Issue: 9
Pages: 1726-1741
Publication
First Author: Ermakov A
Year: 2009
Journal: Dev Dyn
Title: Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development.
Volume: 238
Issue: 3
Pages: 581-94
Publication
First Author: Teilmann SC
Year: 2005
Journal: Mol Reprod Dev
Title: Localization of transient receptor potential ion channels in primary and motile cilia of the female murine reproductive organs.
Volume: 71
Issue: 4
Pages: 444-52
Publication
First Author: Yim H
Year: 2011
Journal: J Am Soc Nephrol
Title: Nek1 and TAZ interact to maintain normal levels of polycystin 2.
Volume: 22
Issue: 5
Pages: 832-7
Publication
First Author: Griffin MD
Year: 1997
Journal: Curr Opin Nephrol Hypertens
Title: Cystic kidney diseases.
Volume: 6
Issue: 3
Pages: 276-83
Publication  
First Author: Kim H
Year: 2014
Journal: Nat Commun
Title: Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism.
Volume: 5
Pages: 5482
Publication
First Author: Fedeles SV
Year: 2011
Journal: Nat Genet
Title: A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation.
Volume: 43
Issue: 7
Pages: 639-47
Publication
First Author: Jurczyk A
Year: 2004
Journal: J Cell Biol
Title: Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.
Volume: 166
Issue: 5
Pages: 637-43
Publication
First Author: Minegishi K
Year: 2021
Journal: Nat Commun
Title: Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex.
Volume: 12
Issue: 1
Pages: 4071
Publication
First Author: Dinsmore C
Year: 2016
Journal: EMBO Rep
Title: Endothelial primary cilia inhibit atherosclerosis.
Volume: 17
Issue: 2
Pages: 156-66
Publication  
First Author: Hajarnis S
Year: 2017
Journal: Nat Commun
Title: microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
Volume: 8
Pages: 14395
Publication
First Author: Ferrè S
Year: 2019
Journal: Kidney Int
Title: Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation.
Volume: 96
Issue: 6
Pages: 1359-1373
Publication
First Author: Lakhia R
Year: 2016
Journal: J Am Soc Nephrol
Title: MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease.
Volume: 27
Issue: 8
Pages: 2319-30
Publication
First Author: Lian P
Year: 2014
Journal: PLoS One
Title: Loss of polycystin-1 inhibits Bicc1 expression during mouse development.
Volume: 9
Issue: 3
Pages: e88816
Publication
First Author: Xia S
Year: 2010
Journal: Development
Title: Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts.
Volume: 137
Issue: 7
Pages: 1075-84
Publication
First Author: Ma M
Year: 2013
Journal: Nat Genet
Title: Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease.
Volume: 45
Issue: 9
Pages: 1004-12
Publication
First Author: Slough J
Year: 2008
Journal: Dev Dyn
Title: Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis.
Volume: 237
Issue: 9
Pages: 2304-14
Publication
First Author: Garcia-Gonzalez MA
Year: 2007
Journal: Hum Mol Genet
Title: Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.
Volume: 16
Issue: 16
Pages: 1940-50
Publication
First Author: Peyronnet R
Year: 2012
Journal: Cell Rep
Title: Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels.
Volume: 1
Issue: 3
Pages: 241-50
Publication
First Author: Tian Y
Year: 2007
Journal: Mol Cell Biol
Title: TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex.
Volume: 27
Issue: 18
Pages: 6383-95
Publication
First Author: Liang G
Year: 2008
Journal: Hum Mol Genet
Title: Polycystin-2 is regulated by endoplasmic reticulum-associated degradation.
Volume: 17
Issue: 8
Pages: 1109-19
Publication  
First Author: Müller U
Year: 1999
Journal: J Cell Sci
Title: Cell adhesion molecules and extracellular-matrix constituents in kidney development and disease.
Volume: 112 ( Pt 22)
Pages: 3855-67
Publication
First Author: LopezJimenez ND
Year: 2006
Journal: J Neurochem
Title: Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.
Volume: 98
Issue: 1
Pages: 68-77
Publication
First Author: Guay-Woodford LM
Year: 2003
Journal: Am J Physiol Renal Physiol
Title: Murine models of polycystic kidney disease: molecular and therapeutic insights.
Volume: 285
Issue: 6
Pages: F1034-49
Publication  
First Author: Lakhia R
Year: 2020
Journal: JCI Insight
Title: Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression.
Volume: 5
Issue: 7
Publication
First Author: Mühlhans J
Year: 2011
Journal: PLoS One
Title: The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors.
Volume: 6
Issue: 10
Pages: e26496
Publication  
First Author: Concepcion D
Year: 2018
Journal: Biol Open
Title: Tbx6 controls left-right asymmetry through regulation of Gdf1.
Volume: 7
Issue: 5
Publication
First Author: Hai Q
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Quantitative Trait Locus Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant.
Volume: 38
Issue: 1
Pages: 83-91
Publication
First Author: Grimes DT
Year: 2016
Journal: PLoS Genet
Title: Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination.
Volume: 12
Issue: 6
Pages: e1006070
Publication
First Author: Shylo NA
Year: 2020
Journal: Dev Biol
Title: Loss of ciliary transition zone protein TMEM107 leads to heterotaxy in mice.
Volume: 460
Issue: 2
Pages: 187-199
Publication
First Author: Bhunia AK
Year: 2002
Journal: Cell
Title: PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2.
Volume: 109
Issue: 2
Pages: 157-68
Publication
First Author: Hwang SH
Year: 2019
Journal: Curr Biol
Title: Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia.
Volume: 29
Issue: 5
Pages: 790-802.e5
Publication
First Author: Makita R
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.
Volume: 294
Issue: 3
Pages: F542-53
Publication
First Author: Cadieux C
Year: 2008
Journal: J Biol Chem
Title: Polycystic kidneys caused by sustained expression of Cux1 isoform p75.
Volume: 283
Issue: 20
Pages: 13817-24
Publication
First Author: Cano DA
Year: 2004
Journal: Development
Title: Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization.
Volume: 131
Issue: 14
Pages: 3457-67
Publication
First Author: Pierreux CE
Year: 2006
Journal: Gastroenterology
Title: The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.
Volume: 130
Issue: 2
Pages: 532-41
Publication
First Author: Goddard LM
Year: 2017
Journal: Dev Cell
Title: Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis.
Volume: 43
Issue: 3
Pages: 274-289.e5
Publication
First Author: Bochkis IM
Year: 2012
Journal: PLoS Genet
Title: Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2.
Volume: 8
Issue: 6
Pages: e1002770
Publication
First Author: Garcia-Gonzalo FR
Year: 2011
Journal: Nat Genet
Title: A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.
Volume: 43
Issue: 8
Pages: 776-84
Publication
First Author: Badgandi HB
Year: 2017
Journal: J Cell Biol
Title: Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.
Volume: 216
Issue: 3
Pages: 743-760
Publication
First Author: Nakaya MA
Year: 2005
Journal: Development
Title: Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.
Volume: 132
Issue: 24
Pages: 5425-36
Publication
First Author: Shih HP
Year: 2012
Journal: Development
Title: A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.
Volume: 139
Issue: 14
Pages: 2488-99
Publication
First Author: Hossain Z
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.
Volume: 104
Issue: 5
Pages: 1631-6
Publication  
First Author: Ramsey IS
Year: 2006
Journal: Annu Rev Physiol
Title: An introduction to TRP channels.
Volume: 68
Pages: 619-47
Publication
First Author: Asai Y
Year: 2010
Journal: J Assoc Res Otolaryngol
Title: A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.
Volume: 11
Issue: 1
Pages: 27-37
Publication  
First Author: Niborski LL
Year: 2021
Journal: Dis Model Mech
Title: Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.
Volume: 14
Issue: 5
Publication
First Author: De Vas MG
Year: 2015
Journal: Development
Title: Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors.
Volume: 142
Issue: 5
Pages: 871-82
Publication
First Author: Lu P
Year: 2022
Journal: Nat Commun
Title: A SOX17-PDGFB signaling axis regulates aortic root development.
Volume: 13
Issue: 1
Pages: 4065
Publication  
First Author: Pujadas G
Year: 2016
Journal: Sci Rep
Title: Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas.
Volume: 6
Pages: 19223
Publication
First Author: Osafune K
Year: 2006
Journal: Development
Title: Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.
Volume: 133
Issue: 1
Pages: 151-61
Publication
First Author: Lechner SG
Year: 2009
Journal: EMBO J
Title: Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.
Volume: 28
Issue: 10
Pages: 1479-91
Publication
First Author: Naillat F
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Calcium signaling induces partial EMT and renal fibrosis in a Wnt4(mCherry) knock-in mouse model.
Volume: 1870
Issue: 5
Pages: 167180
Publication
First Author: Yates LL
Year: 2010
Journal: Hum Mol Genet
Title: The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
Volume: 19
Issue: 23
Pages: 4663-76
Publication  
First Author: Tamplin OJ
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Volume: 9
Pages: 511
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links