| Type |
Details |
Score |
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| First Author: |
Yu J |
| Year: |
2003 |
| Journal: |
Genome Biol |
| Title: |
Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina. |
| Volume: |
4 |
| Issue: |
10 |
| Pages: |
R65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kumar A |
| Year: |
2014 |
| Journal: |
Int J Dev Neurosci |
| Title: |
Analysis of Presenilin 1 and 2 interacting proteins in mouse cerebral cortex during development. |
| Volume: |
38 |
|
| Pages: |
138-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Esteban-Martínez L |
| Year: |
2017 |
| Journal: |
EMBO J |
| Title: |
Programmed mitophagy is essential for the glycolytic switch during cell differentiation. |
| Volume: |
36 |
| Issue: |
12 |
| Pages: |
1688-1706 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shibasaki T |
| Year: |
2013 |
| Journal: |
Cereb Cortex |
| Title: |
PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. |
| Volume: |
23 |
| Issue: |
8 |
| Pages: |
1824-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kumamoto University |
| Year: |
2020 |
|
| Title: |
CARD R-BASE:Center for Animal Resources and Development Database |
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•
•
•
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| Publication |
| First Author: |
Soteriou D |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance. |
| Volume: |
288 |
| Issue: |
26 |
| Pages: |
18716-31 |
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•
•
•
•
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| Publication |
| First Author: |
Yamazaki K |
| Year: |
1998 |
| Journal: |
Genomics |
| Title: |
Genetic mapping of mouse transient receptor potential (Trrp) genes responsible for capacitative calcium entry channels to chromosomes 3, 7, 9, and X. |
| Volume: |
51 |
| Issue: |
2 |
| Pages: |
303-5 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Breckenridge RA |
| Year: |
2013 |
| Journal: |
PLoS Biol |
| Title: |
Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism. |
| Volume: |
11 |
| Issue: |
9 |
| Pages: |
e1001666 |
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•
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| Publication |
| First Author: |
Ayyangar U |
| Year: |
2024 |
| Journal: |
EMBO J |
| Title: |
Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. |
| Volume: |
43 |
| Issue: |
7 |
| Pages: |
1113-1134 |
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•
•
•
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| Publication |
| First Author: |
Lim S |
| Year: |
2021 |
| Journal: |
Elife |
| Title: |
mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia. |
| Volume: |
10 |
|
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•
•
•
•
•
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| First Author: |
Papanicolaou KN |
| Year: |
2012 |
| Journal: |
Circ Res |
| Title: |
Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. |
| Volume: |
111 |
| Issue: |
8 |
| Pages: |
1012-26 |
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•
•
•
•
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| Publication |
| First Author: |
Zhu M |
| Year: |
2021 |
| Journal: |
Biochim Biophys Acta Mol Basis Dis |
| Title: |
A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice. |
| Volume: |
1867 |
| Issue: |
1 |
| Pages: |
165988 |
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•
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| Publication |
| First Author: |
Zhou L |
| Year: |
2017 |
| Journal: |
FASEB J |
| Title: |
Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
132-147 |
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•
•
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| First Author: |
Cankaya M |
| Year: |
2007 |
| Journal: |
BMC Genomics |
| Title: |
An analysis of expression patterns of genes encoding proteins with catalytic activities. |
| Volume: |
8 |
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| Pages: |
232 |
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•
•
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| First Author: |
Yang J |
| Year: |
2024 |
| Journal: |
J Clin Invest |
| Title: |
A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis. |
| Volume: |
134 |
| Issue: |
8 |
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•
•
•
•
•
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| Publication |
| First Author: |
Sakamoto T |
| Year: |
2020 |
| Journal: |
Circ Res |
| Title: |
A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation. |
| Volume: |
126 |
| Issue: |
12 |
| Pages: |
1685-1702 |
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•
•
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| First Author: |
Bulusu V |
| Year: |
2017 |
| Journal: |
Dev Cell |
| Title: |
Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. |
| Volume: |
40 |
| Issue: |
4 |
| Pages: |
331-341.e4 |
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•
•
•
•
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| Publication |
| First Author: |
Werner HB |
| Year: |
2007 |
| Journal: |
J Neurosci |
| Title: |
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. |
| Volume: |
27 |
| Issue: |
29 |
| Pages: |
7717-30 |
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•
•
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| First Author: |
Mager J |
| Year: |
2019 |
| Journal: |
MGI Direct Data Submission |
| Title: |
A Catalog of Early Lethal KOMP Phenotypes |
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| First Author: |
Ko MS |
| Year: |
1998 |
| Journal: |
Hum Mol Genet |
| Title: |
Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. |
| Volume: |
7 |
| Issue: |
12 |
| Pages: |
1967-78 |
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•
•
•
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| First Author: |
Jensen P |
| Year: |
2004 |
| Journal: |
Brain Res Mol Brain Res |
| Title: |
A neurogenomics approach to gene expression analysis in the developing brain. |
| Volume: |
132 |
| Issue: |
2 |
| Pages: |
116-27 |
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•
•
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| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
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•
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| First Author: |
Sansom SN |
| Year: |
2009 |
| Journal: |
PLoS Genet |
| Title: |
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. |
| Volume: |
5 |
| Issue: |
6 |
| Pages: |
e1000511 |
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| First Author: |
Brady KP |
| Year: |
1997 |
| Journal: |
Genome Res |
| Title: |
Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. |
| Volume: |
7 |
| Issue: |
11 |
| Pages: |
1085-93 |
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| First Author: |
Cyagen Biosciences Inc. |
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2022 |
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| Title: |
Cyagen Biosciences Website. |
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| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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| First Author: |
Araki K |
| Year: |
1999 |
| Journal: |
Cell Mol Biol (Noisy-le-grand) |
| Title: |
Exchangeable gene trap using the Cre/mutated lox system. |
| Volume: |
45 |
| Issue: |
5 |
| Pages: |
737-50 |
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| First Author: |
Taniwaki T |
| Year: |
2005 |
| Journal: |
Dev Growth Differ |
| Title: |
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. |
| Volume: |
47 |
| Issue: |
3 |
| Pages: |
163-72 |
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| First Author: |
Mootha VK |
| Year: |
2003 |
| Journal: |
Cell |
| Title: |
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. |
| Volume: |
115 |
| Issue: |
5 |
| Pages: |
629-40 |
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•
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| First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
| Year: |
1993 |
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| Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
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| First Author: |
GO Central curators, GOA curators, Rhea curators |
| Year: |
2020 |
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| Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
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| Title: |
Data Curation Using Mouse Genome Assembly |
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| First Author: |
Hansen J |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9918-22 |
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| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
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| First Author: |
MGI and IMPC |
| Year: |
2018 |
| Journal: |
Database Release |
| Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
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| First Author: |
The Gene Ontology Consortium |
| Year: |
2016 |
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Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
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| First Author: |
Visel A |
| Year: |
2004 |
| Journal: |
Nucleic Acids Res |
| Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
| Volume: |
32 |
| Issue: |
Database issue |
| Pages: |
D552-6 |
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Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
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278-81 |
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Bedogni F |
| Year: |
2021 |
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Front Mol Neurosci |
| Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
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14 |
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Lennon G |
| Year: |
1999 |
| Journal: |
Database Download |
| Title: |
WashU-HHMI Mouse EST Project |
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| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
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1670-9 |
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| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
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| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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| First Author: |
UniProt-GOA |
| Year: |
2012 |
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| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
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Gene Ontology annotation through association of InterPro records with GO terms |
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| First Author: |
Magdaleno S |
| Year: |
2006 |
| Journal: |
PLoS Biol |
| Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
| Volume: |
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Kawai J |
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2001 |
| Journal: |
Nature |
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Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
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6821 |
| Pages: |
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Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
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Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
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MGD Nomenclature Committee |
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Zambrowicz BP |
| Year: |
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Proc Natl Acad Sci U S A |
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
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| First Author: |
GemPharmatech |
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2020 |
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| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
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| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
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Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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| First Author: |
UniProt-GOA |
| Year: |
2012 |
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| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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GOA curators |
| Year: |
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Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
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| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
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| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
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The Gene Ontology Consortium |
| Year: |
2010 |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Diez-Roux G |
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2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
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Mouse Genome Informatics Computational Sequence to Gene Associations |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
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| Title: |
Annotation inferences using phylogenetic trees |
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| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
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| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
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| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
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•
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
531
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
531
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
51
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Regulatory Region |
| Type: |
response_element |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Allele |
| Name: |
pyruvate kinase, muscle; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
pyruvate kinase, muscle; endonuclease-mediated mutation 1, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
pyruvate kinase, muscle; endonuclease-mediated mutation 2, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Allele |
| Name: |
pyruvate kinase, muscle; endonuclease-mediated mutation 4, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Allele |
| Name: |
pyruvate kinase, muscle; endonuclease-mediated mutation 5, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hatanaka O |
| Year: |
2019 |
| Journal: |
mSphere |
| Title: |
Galectin-3 Inhibits Paracoccidioides brasiliensis Growth and Impacts Paracoccidioidomycosis through Multiple Mechanisms. |
| Volume: |
4 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
pyruvate kinase, muscle; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
regulatory region 565; endonuclease-mediated mutation 1, Tim Zacharewski |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giannakopoulos NV |
| Year: |
2005 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. |
| Volume: |
336 |
| Issue: |
2 |
| Pages: |
496-506 |
|
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•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
127
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Makeyev AV |
| Year: |
2005 |
| Journal: |
J Exp Zool A Comp Exp Biol |
| Title: |
HnRNP A3 genes and pseudogenes in the vertebrate genomes. |
| Volume: |
303 |
| Issue: |
4 |
| Pages: |
259-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
David CJ |
| Year: |
2010 |
| Journal: |
Nature |
| Title: |
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. |
| Volume: |
463 |
| Issue: |
7279 |
| Pages: |
364-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Paronetto MP |
| Year: |
2007 |
| Journal: |
J Cell Biol |
| Title: |
The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x. |
| Volume: |
176 |
| Issue: |
7 |
| Pages: |
929-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li ML |
| Year: |
2019 |
| Journal: |
PLoS One |
| Title: |
EV71 3C protease induces apoptosis by cleavage of hnRNP A1 to promote apaf-1 translation. |
| Volume: |
14 |
| Issue: |
9 |
| Pages: |
e0221048 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun Y |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
6349 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim HJ |
| Year: |
2013 |
| Journal: |
Nature |
| Title: |
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. |
| Volume: |
495 |
| Issue: |
7442 |
| Pages: |
467-73 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This entry includes the heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1), a nuclear factor that binds to Pol II transcripts. The family of hnRNP proteins is involved in numerous RNA-related activities []. hnRNPA1 is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and modulation of splice site selection []. hnRNPA1 plays a role in the splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform []. This protein binds to the IRES and inhibits the translation of the apoptosis protease activating factor APAF1. During Enterovirus 71 (EV71) infection, APAF1 expression is essential for virus-induced apoptosis and viral particle release [].hnRNPA1 consists of two RNA recognition motifs (RRM1 and RRM2) followed by an unstructured low complexity (LC) C-terminal domain, represented in this entry [, , ]. This domain, shared by hnRNPA1 and hnRNPA2/B1, can mediate protein-protein and protein-RNA interactions and it is involved in amyloid aggregation, leading to neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) and multisystem proteinopathy (MSP) [, ]. |
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