|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 401 to 500 out of 8636 for Pml

<< First    < Previous  |  Next >    Last >>
0.03s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
28691927 | J:354323
First Author: Wang YT
Year: 2017
Journal: J Clin Invest
Title: Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment.
Volume: 127
Issue: 8
Pages: 2982-2997
•
•
•
•
•
Publication
15351967 | J:92879
First Author: Dellaire G
Year: 2004
Journal: Bioessays
Title: PML nuclear bodies: dynamic sensors of DNA damage and cellular stress.
Volume: 26
Issue: 9
Pages: 963-77
•
•
•
•
•
Genotype
Genotype
Symbol: Sumo1/Sumo1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
MP Term
MP:0010004 | abnormal paramedian lobule morphology
•
•
•
•
•
Publication
23444137 | J:228107
First Author: Chang FT
Year: 2013
Journal: Nucleic Acids Res
Title: PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells.
Volume: 41
Issue: 8
Pages: 4447-58
•
•
•
•
•
Publication
25299576 | J:223568
First Author: Zhang M
Year: 2014
Journal: PLoS One
Title: Protein kinase A activation enhances β-catenin transcriptional activity through nuclear localization to PML bodies.
Volume: 9
Issue: 10
Pages: e109523
•
•
•
•
•
Publication
19258395 | J:150532
First Author: Briers S
Year: 2009
Journal: J Cell Sci
Title: KRAB zinc-finger proteins localise to novel KAP1-containing foci that are adjacent to PML nuclear bodies.
Volume: 122
Issue: Pt 7
Pages: 937-46
•
•
•
•
•
Publication
10688806 | J:60790
First Author: Kogan SC
Year: 2000
Journal: Blood
Title: Leukemia initiated by PMLRARalpha: the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable.
Volume: 95
Issue: 5
Pages: 1541-50
•
•
•
•
•
Publication
37655965 | J:351875
First Author: Bercier P
Year: 2023
Journal: Cancer Discov
Title: Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.
Volume: 13
Issue: 12
Pages: 2548-2565
•
•
•
•
•
Publication
31882856 | J:307194
First Author: Nagashima S
Year: 2019
Journal: Sci Rep
Title: Critical role of CRAG, a splicing variant of centaurin-γ3/AGAP3, in ELK1-dependent SRF activation at PML bodies.
Volume: 9
Issue: 1
Pages: 20107
•
•
•
•
•
DO Term
DOID:643 | progressive multifocal leukoencephalopathy
•
•
•
•
•
Interaction Experiment
Bernardi R (2006)
Description: PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.
•
•
•
•
•
Interaction Experiment
Louria-Hayon I (2009)
Description: E6AP promotes the degradation of the PML tumor suppressor.
•
•
•
•
•
Interaction Experiment
Miki T (2012)
Description: PML regulates PER2 nuclear localization and circadian function.
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6761590
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-10
Strength: Present
Sex: Male
Emaps: EMAPS:2910624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7628670
Age: embryonic day 16.5
Image: 1D ScAtrxKO
Note: 77% of regular sized and 94% of giant Gata4 foci co-localized with PML NBs.
Specimen Label: 1D ScAtrxKO
Detected: true
Specimen Num: 9
•
•
•
•
•
Protein Coding Gene
MGI:2442599 | Simc1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1917193 | Lrch4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1197010 | Sumo1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1923257 | Zmym2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
12837286 | -
First Author: Shyu HW
Year: 2003
Journal: Exp Cell Res
Title: Forced expression of RNF36 induces cell apoptosis.
Volume: 287
Issue: 2
Pages: 301-13
•
•
•
•
•
Publication
14645235 | -
First Author: Fanelli M
Year: 2004
Journal: J Biol Chem
Title: The coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasome.
Volume: 279
Issue: 7
Pages: 5374-9
•
•
•
•
•
Interaction Experiment
Yoshida H (2007)
Description: PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation.
•
•
•
•
•
Interaction Experiment
Cappadocia L (2015)
Description: Structural and functional characterization of the phosphorylation-dependent interaction between PML and SUMO1.
•
•
•
•
•
Interaction Experiment
Liu Y (2017)
Description: Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates Cardiac Fibrosis.
•
•
•
•
•
Interaction Experiment
Salsman J (2017)
Description: Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres.
•
•
•
•
•
Interaction Experiment
Nagashima S (2019)
Description: Critical role of CRAG, a splicing variant of centaurin-?3/AGAP3, in ELK1-dependent SRF activation at PML bodies.
•
•
•
•
•
Allele
Pml<em1Smoc> | MGI:7288909
Name: promyelocytic leukemia; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Protein Coding Gene
MGI:105113 | Gcna
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Allele
Tg(CTSG-RARA/PML)2683Ley | MGI:3620139
Name: transgene insertion 2683, Timothy Ley
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Protein Coding Gene
MGI:1333839 | Magea4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:3588211 | Magea10
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1333793 | Magea2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1913849 | Rdm1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
18480450 | -
First Author: Ullman AJ
Year: 2008
Journal: J Virol
Title: Cellular proteins PML and Daxx mediate an innate antiviral defense antagonized by the adenovirus E4 ORF3 protein.
Volume: 82
Issue: 15
Pages: 7325-35
•
•
•
•
•
Protein Coding Gene
MGI:2137356 | Trim16
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1889273 | Fxyd1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
28870505 | J:256839
 
First Author: Ackermann MA
Year: 2017
Journal: J Mol Cell Cardiol
Title: TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism.
Volume: 112
Pages: 49-57
•
•
•
•
•
Publication
33101056 | J:308310
 
First Author: Peczkowski KK
Year: 2020
Journal: Front Physiol
Title: Muscle Twitch Kinetics Are Dependent on Muscle Group, Disease State, and Age in Duchenne Muscular Dystrophy Mouse Models.
Volume: 11
Pages: 568909
•
•
•
•
•
Publication
9002938 | J:77881
First Author: Grisolano JL
Year: 1997
Journal: Blood
Title: Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences.
Volume: 89
Issue: 2
Pages: 376-87
•
•
•
•
•
Protein Coding Gene
MGI:1916973 | Rpain
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Allele
Tg(CTSG-PML/RARA)135Ley | MGI:3620013
Name: transgene insertion 135, Timothy Ley
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Protein Coding Gene
MGI:1343177 | Calcoco2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1919943 | Zcchc12
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1333832 | Magea3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1333838 | Magea5
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Allele
Pml<tm1.1Ews> | MGI:6195046
Name: promyelocytic leukemia; targeted mutation 1.1, Eva W Stratford
Allele Type: Targeted
Attribute String: Not Specified
•
•
•
•
•
Genotype
Genotype
Symbol: Pml/Pml
Background: FVB.129P2-Pml
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Protein Coding Gene
MGI:2684975 | Ciart
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Strain
MGI:3618826 | C3;B6-Tg(CTSG-RARa/PML)2683Ley/Nci
Attribute String: mutant stock, transgenic
•
•
•
•
•
Strain
MGI:6429380 | C57BL/6JSmoc-Pml<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Publication
12470659 | -
First Author: Naka K
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Recruitment of NBS1 into PML oncogenic domains via interaction with SP100 protein.
Volume: 299
Issue: 5
Pages: 863-71
•
•
•
•
•
Publication
12717420 | -
First Author: Roussigne M
Year: 2003
Journal: Oncogene
Title: THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodies.
Volume: 22
Issue: 16
Pages: 2432-42
•
•
•
•
•
Publication
18809579 | -
First Author: Shima Y
Year: 2008
Journal: Mol Cell Biol
Title: PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation.
Volume: 28
Issue: 23
Pages: 7126-38
•
•
•
•
•
Publication
18408734 | -
First Author: Tatham MH
Year: 2008
Journal: Nat Cell Biol
Title: RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation.
Volume: 10
Issue: 5
Pages: 538-46
•
•
•
•
•
Publication
25497731 | -
First Author: Cappadocia L
Year: 2015
Journal: Structure
Title: Structural and functional characterization of the phosphorylation-dependent interaction between PML and SUMO1.
Volume: 23
Issue: 1
Pages: 126-38
•
•
•
•
•
Publication
28143738 | -
First Author: Liu Y
Year: 2017
Journal: Mol Ther
Title: Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates Cardiac Fibrosis.
Volume: 25
Issue: 3
Pages: 666-678
•
•
•
•
•
Publication
28358373 | -
First Author: Salsman J
Year: 2017
Journal: Cell Death Dis
Title: Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres.
Volume: 8
Issue: 3
Pages: e2724
•
•
•
•
•
Publication
22022399 | -
First Author: Georges A
Year: 2011
Journal: PLoS One
Title: SUMOylation of the Forkhead transcription factor FOXL2 promotes its stabilization/activation through transient recruitment to PML bodies.
Volume: 6
Issue: 10
Pages: e25463
•
•
•
•
•
Protein Coding Gene
MGI:1891307 | Ubn1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
34294193 | J:328078
First Author: Martin PT
Year: 2021
Journal: Am J Pathol
Title: Serum Antibodies to N-Glycolylneuraminic Acid Are Elevated in Duchenne Muscular Dystrophy and Correlate with Increased Disease Pathology in Cmah-/-mdx Mice.
Volume: 191
Issue: 8
Pages: 1474-1486
•
•
•
•
•
Publication
30759207 | J:275661
First Author: Hauck JS
Year: 2019
Journal: Hum Mol Genet
Title: Mineralocorticoid receptor antagonists improve membrane integrity independent of muscle force in muscular dystrophy.
Volume: 28
Issue: 12
Pages: 2030-2045
•
•
•
•
•
Publication
28790199 | J:267323
First Author: El Refaey M
Year: 2017
Journal: Circ Res
Title: In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.
Volume: 121
Issue: 8
Pages: 923-929
•
•
•
•
•
Protein Coding Gene
MGI:1860486 | Tdp2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:2136841 | Morc3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Strain
MGI:3618825 | C3;B6-Tg(CTSG-PML/RARA)135Ley/Nci
Attribute String: transgenic, mutant stock
•
•
•
•
•
Publication
26041820 | J:225603
First Author: Bräuer-Hartmann D
Year: 2015
Journal: Cancer Res
Title: PML/RARα-Regulated miR-181a/b Cluster Targets the Tumor Suppressor RASSF1A in Acute Promyelocytic Leukemia.
Volume: 75
Issue: 16
Pages: 3411-24
•
•
•
•
•
Publication
28025581 | J:245804
First Author: Ronchini C
Year: 2017
Journal: Leukemia
Title: PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias.
Volume: 31
Issue: 9
Pages: 1975-1986
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CTSG-PML/RARA)135Ley/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Mleu1/? Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Mleu2/? Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Mleu4/? Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Mleu5/? Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spw1/Spw1 Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spw2/? Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spw3/Spw3 Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spw4/Spw4 Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Spw5/Spw5 Tg(CTSG-PML/RARA)135Ley/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CTSG-PML/RARA)135Ley/? Wbcc1/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CTSG-PML/RARA)135Ley/? Wbcc2/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CTSG-PML/RARA)135Ley/? Wbcc3/?
Background: involves: C3H/HeJ * C57BL/6J * SWR/J
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
27000403 | -
 
First Author: Masroori N
Year: 2016
Journal: Retrovirology
Title: The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific, isoform-specific fashion.
Volume: 13
Pages: 19
•
•
•
•
•
Publication
9420283 | -
First Author: Borden KL
Year: 1998
Journal: J Virol
Title: An arenavirus RING (zinc-binding) protein binds the oncoprotein promyelocyte leukemia protein (PML) and relocates PML nuclear bodies to the cytoplasm.
Volume: 72
Issue: 1
Pages: 758-66
•
•
•
•
•
Publication
8695863 | -
First Author: Dent AL
Year: 1996
Journal: Blood
Title: LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies.
Volume: 88
Issue: 4
Pages: 1423-6
•
•
•
•
•
Publication
16648851 | -
First Author: Roscioli T
Year: 2006
Journal: Nat Genet
Title: Mutations in the gene encoding the PML nuclear body protein Sp110 are associated with immunodeficiency and hepatic veno-occlusive disease.
Volume: 38
Issue: 6
Pages: 620-2
•
•
•
•
•
Protein Coding Gene
MGI:2147679 | Patl1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:2137896 | Zfp451
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1924968 | Slf2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1349399 | Casp8ap2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:2136825 | N4bp1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1916892 | Mlip
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:99430 | Hira
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1915978 | Trp53inp2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1096875 | Wdfy3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:2444898 | Chfr
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
16675706 | J:115068
First Author: Chan IT
Year: 2006
Journal: Blood
Title: Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease.
Volume: 108
Issue: 5
Pages: 1708-15
•
•
•
•
•
Publication
12750176 | J:84230
First Author: Westervelt P
Year: 2003
Journal: Blood
Title: High-penetrance mouse model of acute promyelocytic leukemia with very low levels of PML-RARalpha expression.
Volume: 102
Issue: 5
Pages: 1857-65
•
•
•
•
•
Publication
26080083 | J:237807
First Author: Bäumer N
Year: 2015
Journal: PLoS One
Title: A Limited Role for the Cell Cycle Regulator Cyclin A1 in Murine Leukemogenesis.
Volume: 10
Issue: 6
Pages: e0129147
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CTSG-PML/RARA)135Ley/? Tg(CTSG-RARA/PML)#Ley/?
Background: involves: C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CTSG-PML/RARA)135Ley/? Tg(CTSG-RARA/PML)2544Ley/?
Background: involves: C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom