Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3599822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280922 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1833322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1821522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3557722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1702122 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1668822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1802422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1768022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the skull (base and vault). |
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309516 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:2672022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422884 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in whisker follicle. |
Specimen Label: |
MH3297; Specimen C4408 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
137
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakajo S |
Year: |
1993 |
Journal: |
Eur J Biochem |
Title: |
A new brain-specific 14-kDa protein is a phosphoprotein. Its complete amino acid sequence and evidence for phosphorylation. |
Volume: |
217 |
Issue: |
3 |
Pages: |
1057-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jedrzejczak R |
Year: |
2011 |
Journal: |
Acta Crystallogr D Biol Crystallogr |
Title: |
Human Suv3 protein reveals unique features among SF2 helicases. |
Volume: |
67 |
Issue: |
Pt 11 |
Pages: |
988-96 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors [, ]. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. All synucleins have in common a highly conserved α-helical lipid-binding motif with similarity to the class-A2 lipid-binding domains of the exchangeable apolipoproteins [].Synuclein family members are not found outside vertebrates, although they have some conserved structural similarity with plant 'late-embryo-abundant' proteins. The alpha- and beta-synuclein proteins are found primarily in brain tissue, where they are seen mainly in presynaptic terminals [, ]. The gamma-synuclein protein is found primarily in the peripheral nervous system and retina, but its expression in breast tumors []is a marker for tumor progression [].Normal cellular functions have not been determined for any of the synuclein proteins,although some data suggest a role in the regulation of membrane stability and/or turnover.Mutations in alpha-synuclein are associated with rare familial cases of early-onset Parkinson'sdisease, and the protein accumulates abnormally in Parkinson's disease, Alzheimer's disease,and several other neurodegenerative illnesses []. Beta-synuclein, also known as PNP 14, is expressed in the brain, specifically in synapses aroundneurons, but not in glial cells. The protein, which has been designateda phosphoneuroprotein, has been found to be phosphorylated in vitro and invivo []. It is believed that the physiological functions of beta-synuclein may be controlled by the phosphorylation reaction. |
|
•
•
•
•
•
|
Publication |
First Author: |
Gofflot F |
Year: |
1998 |
Journal: |
Int J Dev Biol |
Title: |
Genetic patterning of the posterior neuropore region of curly tail mouse embryos: deficiency of Wnt5a expression. |
Volume: |
42 |
Issue: |
5 |
Pages: |
637-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kulkarni AD |
Year: |
1992 |
Journal: |
Transplantation |
Title: |
Immunohemopoietic effects of dietary nucleotide restriction in mice. |
Volume: |
53 |
Issue: |
2 |
Pages: |
467-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schröder I |
Year: |
2003 |
Journal: |
FEMS Microbiol Rev |
Title: |
Microbial ferric iron reductases. |
Volume: |
27 |
Issue: |
2-3 |
Pages: |
427-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peeters MC |
Year: |
1998 |
Journal: |
Dev Dyn |
Title: |
Role of differential cell proliferation in the tail bud in aberrant mouse neurulation. |
Volume: |
211 |
Issue: |
4 |
Pages: |
382-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rogers TD |
Year: |
2022 |
Journal: |
Front Physiol |
Title: |
Regional Differences in Mucociliary Clearance in the Upper and Lower Airways. |
Volume: |
13 |
|
Pages: |
842592 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
133
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Watanabe S |
Year: |
1995 |
Journal: |
J Biol Chem |
Title: |
Purification, cloning, and expression of murine uridine phosphorylase. |
Volume: |
270 |
Issue: |
20 |
Pages: |
12191-6 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
311
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
320
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
311
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
325
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
250
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
320
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
143
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
286
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
149
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
325
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
306
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
338
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Bruening W |
Year: |
2000 |
Journal: |
Cancer |
Title: |
Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary. |
Volume: |
88 |
Issue: |
9 |
Pages: |
2154-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Christendat D |
Year: |
2000 |
Journal: |
Nat Struct Biol |
Title: |
Structural proteomics of an archaeon. |
Volume: |
7 |
Issue: |
10 |
Pages: |
903-9 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
779
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Takehara M |
Year: |
1995 |
Journal: |
Biosci Biotechnol Biochem |
Title: |
Molecular cloning and nucleotide sequence of purine nucleoside phosphorylase and uridine phosphorylase genes from Klebsiella sp. |
Volume: |
59 |
Issue: |
10 |
Pages: |
1987-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cacciapuoti G |
Year: |
1994 |
Journal: |
J Biol Chem |
Title: |
Purification and characterization of extremely thermophilic and thermostable 5'-methylthioadenosine phosphorylase from the archaeon Sulfolobus solfataricus. Purine nucleoside phosphorylase activity and evidence for intersubunit disulfide bonds. |
Volume: |
269 |
Issue: |
40 |
Pages: |
24762-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lavedan C |
Year: |
1998 |
Journal: |
Genome Res |
Title: |
The synuclein family. |
Volume: |
8 |
Issue: |
9 |
Pages: |
871-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
George JM |
Year: |
2002 |
Journal: |
Genome Biol |
Title: |
The synucleins. |
Volume: |
3 |
Issue: |
1 |
Pages: |
REVIEWS3002 |
|
•
•
•
•
•
|
Publication |
First Author: |
Perrin RJ |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis. |
Volume: |
275 |
Issue: |
44 |
Pages: |
34393-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iwai A |
Year: |
1995 |
Journal: |
Neuron |
Title: |
The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. |
Volume: |
14 |
Issue: |
2 |
Pages: |
467-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakajo S |
Year: |
1994 |
Journal: |
Brain Res Mol Brain Res |
Title: |
Localization of phosphoneuroprotein 14 (PNP 14) and its mRNA expression in rat brain determined by immunocytochemistry and in situ hybridization. |
Volume: |
27 |
Issue: |
1 |
Pages: |
81-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ji H |
Year: |
1997 |
Journal: |
Cancer Res |
Title: |
Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing. |
Volume: |
57 |
Issue: |
4 |
Pages: |
759-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goedert M |
Year: |
2001 |
Journal: |
Nat Rev Neurosci |
Title: |
Alpha-synuclein and neurodegenerative diseases. |
Volume: |
2 |
Issue: |
7 |
Pages: |
492-501 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toney MD |
Year: |
2005 |
Journal: |
Arch Biochem Biophys |
Title: |
Reaction specificity in pyridoxal phosphate enzymes. |
Volume: |
433 |
Issue: |
1 |
Pages: |
279-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hayashi H |
Year: |
1995 |
Journal: |
J Biochem |
Title: |
Pyridoxal enzymes: mechanistic diversity and uniformity. |
Volume: |
118 |
Issue: |
3 |
Pages: |
463-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eliot AC |
Year: |
2004 |
Journal: |
Annu Rev Biochem |
Title: |
Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations. |
Volume: |
73 |
|
Pages: |
383-415 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mozzarelli A |
Year: |
2006 |
Journal: |
Chem Rec |
Title: |
Exploring the pyridoxal 5'-phosphate-dependent enzymes. |
Volume: |
6 |
Issue: |
5 |
Pages: |
275-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clayton PT |
Year: |
2006 |
Journal: |
J Inherit Metab Dis |
Title: |
B6-responsive disorders: a model of vitamin dependency. |
Volume: |
29 |
Issue: |
2-3 |
Pages: |
317-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
John RA |
Year: |
1995 |
Journal: |
Biochim Biophys Acta |
Title: |
Pyridoxal phosphate-dependent enzymes. |
Volume: |
1248 |
Issue: |
2 |
Pages: |
81-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fan KQ |
Year: |
2019 |
Journal: |
Cell |
Title: |
Stress-Induced Metabolic Disorder in Peripheral CD4(+) T Cells Leads to Anxiety-like Behavior. |
Volume: |
179 |
Issue: |
4 |
Pages: |
864-879.e19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|