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Search results 401 to 500 out of 1214 for Ppara

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Type Details Score
Publication
First Author: Luo Y
Year: 2019
Journal: Gastroenterology
Title: Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6.
Volume: 157
Issue: 3
Pages: 744-759.e4
Publication    
First Author: Kalliora C
Year: 2019
Journal: JCI Insight
Title: Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction.
Volume: 5
Publication  
First Author: Rangasamy SB
Year: 2023
Journal: Brain Behav Immun
Title: Treadmill workout activates PPARα in the hippocampus to upregulate ADAM10, decrease plaques and improve cognitive functions in 5XFAD mouse model of Alzheimer's disease.
Volume: 109
Pages: 204-218
Publication  
First Author: Patel D
Year: 2020
Journal: JCI Insight
Title: Upregulation of BDNF and hippocampal functions by a hippocampal ligand of PPARα.
Volume: 5
Issue: 10
Publication  
First Author: Shete V
Year: 2018
Journal: Int J Mol Sci
Title: Mouse Cardiac Pde1C Is a Direct Transcriptional Target of Pparα.
Volume: 19
Issue: 12
Publication
First Author: Manieri E
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma.
Volume: 117
Issue: 28
Pages: 16492-16499
Publication
First Author: Hu Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction.
Volume: 110
Issue: 38
Pages: 15401-6
Publication
First Author: Nakagawa Y
Year: 2014
Journal: Endocrinology
Title: Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.
Volume: 155
Issue: 12
Pages: 4706-19
Publication
First Author: Peeters A
Year: 2015
Journal: Biochim Biophys Acta
Title: Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation.
Volume: 1853
Issue: 2
Pages: 285-98
Publication  
First Author: Azar S
Year: 2020
Journal: Mol Metab
Title: Reversal of diet-induced hepatic steatosis by peripheral CB1 receptor blockade in mice is p53/miRNA-22/SIRT1/PPARα dependent.
Volume: 42
Pages: 101087
Publication
First Author: Byun S
Year: 2020
Journal: Nat Commun
Title: Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase.
Volume: 11
Issue: 1
Pages: 807
Publication
First Author: Liu S
Year: 2021
Journal: iScience
Title: Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9+ hepatocyte fate.
Volume: 24
Issue: 9
Pages: 103003
Publication
First Author: Finck BN
Year: 2006
Journal: Cell Metab
Title: Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.
Volume: 4
Issue: 3
Pages: 199-210
Publication
First Author: Vegiopoulos A
Year: 2010
Journal: Science
Title: Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes.
Volume: 328
Issue: 5982
Pages: 1158-61
Publication
First Author: Trent CM
Year: 2014
Journal: J Lipid Res
Title: Lipoprotein lipase activity is required for cardiac lipid droplet production.
Volume: 55
Issue: 4
Pages: 645-58
Publication  
First Author: Chen X
Year: 2017
Journal: Toxicology
Title: Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis.
Volume: 379
Pages: 12-21
Publication
First Author: Li Y
Year: 2009
Journal: J Mol Cell Cardiol
Title: Peroxisome proliferator-activated receptor delta regulates mitofusin 2 expression in the heart.
Volume: 46
Issue: 6
Pages: 876-82
Publication
First Author: Corbett GT
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.
Volume: 112
Issue: 27
Pages: 8445-50
Publication
First Author: Yang X
Year: 2023
Journal: J Biol Chem
Title: Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR.
Volume: 299
Issue: 3
Pages: 102955
Publication
First Author: Shen Y
Year: 2020
Journal: Cell Rep
Title: Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function.
Volume: 30
Issue: 9
Pages: 3079-3091.e5
Publication  
First Author: Li D
Year: 2010
Journal: BMC Genomics
Title: Regulation of gene expression by FSP27 in white and brown adipose tissue.
Volume: 11
Pages: 446
Publication  
First Author: Hajarnis S
Year: 2017
Journal: Nat Commun
Title: microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
Volume: 8
Pages: 14395
Publication
First Author: Cheng X
Year: 2008
Journal: Toxicol Sci
Title: Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
Volume: 106
Issue: 1
Pages: 29-36
Publication  
First Author: Chen X
Year: 2023
Journal: Free Radic Biol Med
Title: Under peroxisome proliferation acyl-CoA oxidase coordinates with catalase to enhance ethanol metabolism.
Volume: 208
Pages: 221-228
Publication
First Author: Guo D
Year: 2007
Journal: J Biol Chem
Title: Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.
Volume: 282
Issue: 50
Pages: 36766-76
Publication
First Author: Settembre C
Year: 2013
Journal: Nat Cell Biol
Title: TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
Volume: 15
Issue: 6
Pages: 647-58
Publication
First Author: Mana MD
Year: 2021
Journal: Cell Rep
Title: High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity.
Volume: 35
Issue: 10
Pages: 109212
Publication
First Author: Jordan S
Year: 2019
Journal: Cell
Title: Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.
Volume: 178
Issue: 5
Pages: 1102-1114.e17
Publication
First Author: Calléja C
Year: 2006
Journal: Genes Dev
Title: Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes.
Volume: 20
Issue: 11
Pages: 1525-38
Publication
First Author: Clifford BL
Year: 2021
Journal: Cell Metab
Title: FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption.
Volume: 33
Issue: 8
Pages: 1671-1684.e4
Publication  
First Author: Huen SC
Year: 2021
Journal: J Exp Med
Title: Hepatic FGF21 preserves thermoregulation and cardiovascular function during bacterial inflammation.
Volume: 218
Issue: 10
Publication
First Author: Vernia S
Year: 2016
Journal: Cell Rep
Title: Fibroblast Growth Factor 21 Mediates Glycemic Regulation by Hepatic JNK.
Volume: 14
Issue: 10
Pages: 2273-80
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Issemann I
Year: 1990
Journal: Nature
Title: Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators.
Volume: 347
Issue: 6294
Pages: 645-50
Publication
First Author: Chakravarthy MV
Year: 2009
Journal: Cell
Title: Identification of a physiologically relevant endogenous ligand for PPARalpha in liver.
Volume: 138
Issue: 3
Pages: 476-88
Publication  
First Author: Chen N
Year: 1992
Journal: Biochem J
Title: Induction of the major integral membrane protein of mouse liver peroxisomes by peroxisome proliferators.
Volume: 283 ( Pt 2)
Pages: 605-10
Publication
First Author: Montagner A
Year: 2016
Journal: Gut
Title: Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.
Volume: 65
Issue: 7
Pages: 1202-14
Publication
First Author: Régnier M
Year: 2020
Journal: Sci Rep
Title: Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity.
Volume: 10
Issue: 1
Pages: 6489
Publication
First Author: Stec DE
Year: 2019
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity.
Volume: 317
Issue: 5
Pages: R733-R745
Publication
First Author: Badmus OO
Year: 2023
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Loss of hepatic PPARα in mice causes hypertension and cardiovascular disease.
Volume: 325
Issue: 1
Pages: R81-R95
Publication
First Author: Yagai T
Year: 2021
Journal: Cell Rep
Title: Feedback repression of PPARα signaling by Let-7 microRNA.
Volume: 36
Issue: 6
Pages: 109506
Publication
First Author: Esmaeili MA
Year: 2016
Journal: Hum Mol Genet
Title: Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.
Volume: 25
Issue: 2
Pages: 317-27
Publication
First Author: Fillmore N
Year: 2022
Journal: PLoS One
Title: Cardiac specific knock-down of peroxisome proliferator activated receptor α prevents fasting-induced cardiac lipid accumulation and reduces perilipin 2.
Volume: 17
Issue: 3
Pages: e0265007
Publication
First Author: Gordon DM
Year: 2020
Journal: J Biol Chem
Title: Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor α.
Volume: 295
Issue: 29
Pages: 9804-9822
Publication
First Author: Liang N
Year: 2019
Journal: Nat Commun
Title: Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα.
Volume: 10
Issue: 1
Pages: 1684
Publication  
First Author: Caillon A
Year: 2018
Journal: Metabolism
Title: The OEA effect on food intake is independent from the presence of PPARα in the intestine and the nodose ganglion, while the impact of OEA on energy expenditure requires the presence of PPARα in mice.
Volume: 87
Pages: 13-17
Publication
First Author: Yamazaki K
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Microarray analysis of gene expression changes in mouse liver induced by peroxisome proliferator- activated receptor alpha agonists.
Volume: 290
Issue: 3
Pages: 1114-22
Publication
First Author: Corton JC
Year: 2000
Journal: Mutat Res
Title: Central role of PPARalpha in the mechanism of action of hepatocarcinogenic peroxisome proliferators.
Volume: 448
Issue: 2
Pages: 139-51
Publication
First Author: Beck F
Year: 1992
Journal: Proc Biol Sci
Title: The ontogeny of peroxisome-proliferator-activated receptor gene expression in the mouse and rat.
Volume: 247
Issue: 1319
Pages: 83-7
Publication
First Author: Gearing KL
Year: 1994
Journal: J Nutr
Title: Fatty acid activation of the peroxisome proliferator activated receptor, a member of the nuclear receptor gene superfamily.
Volume: 124
Issue: 8 Suppl
Pages: 1284S-1288S
Publication
First Author: Hsu MH
Year: 1995
Journal: Mol Pharmacol
Title: A single amino acid change in the mouse peroxisome proliferator-activated receptor alpha alters transcriptional responses to peroxisome proliferators.
Volume: 48
Issue: 3
Pages: 559-67
Publication
First Author: Sheu MY
Year: 2002
Journal: J Invest Dermatol
Title: Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models.
Volume: 118
Issue: 1
Pages: 94-101
Publication
First Author: Bronner M
Year: 2004
Journal: Biochem J
Title: Kinase-independent transcriptional co-activation of peroxisome proliferator-activated receptor alpha by AMP-activated protein kinase.
Volume: 384
Issue: Pt 2
Pages: 295-305
Publication
First Author: Hostetler HA
Year: 2005
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor alpha interacts with high affinity and is conformationally responsive to endogenous ligands.
Volume: 280
Issue: 19
Pages: 18667-82
Publication
First Author: Michalik L
Year: 2005
Journal: Mol Endocrinol
Title: Selective expression of a dominant-negative form of peroxisome proliferator-activated receptor in keratinocytes leads to impaired epidermal healing.
Volume: 19
Issue: 9
Pages: 2335-48
Publication
First Author: Lee H
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Ginsenoside Rf, a component of ginseng, regulates lipoprotein metabolism through peroxisome proliferator-activated receptor alpha.
Volume: 339
Issue: 1
Pages: 196-203
Publication
First Author: Yang Q
Year: 2006
Journal: J Invest Dermatol
Title: Alterations in skin and stratified epithelia by constitutively activated PPARalpha.
Volume: 126
Issue: 2
Pages: 374-85
Publication
First Author: Lefebvre P
Year: 2006
Journal: J Clin Invest
Title: Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis.
Volume: 116
Issue: 3
Pages: 571-80
Publication
First Author: Hostetler HA
Year: 2006
Journal: Biochemistry
Title: Very-long-chain and branched-chain fatty acyl-CoAs are high affinity ligands for the peroxisome proliferator-activated receptor alpha (PPARalpha).
Volume: 45
Issue: 24
Pages: 7669-81
Publication
First Author: Woods CG
Year: 2007
Journal: Free Radic Biol Med
Title: Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase.
Volume: 42
Issue: 3
Pages: 335-42
Publication
First Author: Ahmed W
Year: 2006
Journal: Circ Res
Title: High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: a candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion.
Volume: 98
Issue: 4
Pages: 490-8
Publication
First Author: Pogribny IP
Year: 2007
Journal: Mutat Res
Title: Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha.
Volume: 625
Issue: 1-2
Pages: 62-71
Publication
First Author: Dubrac S
Year: 2007
Journal: J Immunol
Title: Peroxisome proliferator-activated receptor-alpha activation inhibits Langerhans cell function.
Volume: 178
Issue: 7
Pages: 4362-72
Publication  
First Author: Yi JH
Year: 2008
Journal: Brain Res
Title: PPARgamma agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms.
Volume: 1244
Pages: 164-72
Publication
First Author: Wen G
Year: 2011
Journal: Biochem Pharmacol
Title: Mouse γ-butyrobetaine dioxygenase is regulated by peroxisome proliferator-activated receptor α through a PPRE located in the proximal promoter.
Volume: 82
Issue: 2
Pages: 175-83
Publication
First Author: Georgiadi A
Year: 2012
Journal: Physiol Genomics
Title: Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart.
Volume: 44
Issue: 6
Pages: 352-61
Publication
First Author: Wen G
Year: 2012
Journal: Biochim Biophys Acta
Title: The mouse gene encoding the carnitine biosynthetic enzyme 4-N-trimethylaminobutyraldehyde dehydrogenase is regulated by peroxisome proliferator-activated receptor α.
Volume: 1819
Issue: 5
Pages: 357-65
Publication
First Author: Bolsoni-Lopes A
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPARα-dependent manner.
Volume: 305
Issue: 9
Pages: E1093-102
Publication
First Author: Moran E
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Protective and antioxidant effects of PPARα in the ischemic retina.
Volume: 55
Issue: 7
Pages: 4568-76
Publication
First Author: Takahashi H
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Over-expression of PPARα in obese mice adipose tissue improves insulin sensitivity.
Volume: 493
Issue: 1
Pages: 108-114
Publication  
First Author: Régnier M
Year: 2018
Journal: Mol Cell Endocrinol
Title: Insights into the role of hepatocyte PPARα activity in response to fasting.
Volume: 471
Pages: 75-88
Publication
First Author: Xie G
Year: 2019
Journal: Am J Pathol
Title: Hepatocyte Peroxisome Proliferator-Activated Receptor α Enhances Liver Regeneration after Partial Hepatectomy in Mice.
Volume: 189
Issue: 2
Pages: 272-282
Publication
First Author: De Silva TM
Year: 2018
Journal: Hypertension
Title: Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging.
Volume: 72
Issue: 1
Pages: 227-234
Publication
First Author: Iwaki T
Year: 2019
Journal: Physiol Rep
Title: PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis.
Volume: 7
Issue: 10
Pages: e14078
Publication  
First Author: Chikahisa S
Year: 2019
Journal: Behav Brain Res
Title: Enhancement of fear learning in PPARα knockout mice.
Volume: 359
Pages: 664-670
Publication
First Author: Yin X
Year: 2020
Journal: Cell Rep
Title: PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction.
Volume: 33
Issue: 3
Pages: 108278
Publication
First Author: Wang M
Year: 2021
Journal: iScience
Title: Programmed PPAR-α downregulation induces inflammaging by suppressing fatty acid catabolism in monocytes.
Volume: 24
Issue: 7
Pages: 102766
Publication
First Author: Du WW
Year: 2015
Journal: Mol Ther
Title: Inhibition of Dexamethasone-induced Fatty Liver Development by Reducing miR-17-5p Levels.
Volume: 23
Issue: 7
Pages: 1222-1233
Publication
First Author: Zhang N
Year: 2014
Journal: Oncotarget
Title: Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-κB signaling pathway.
Volume: 5
Issue: 18
Pages: 8330-40
Publication
First Author: Kim JA
Year: 2016
Journal: Muscle Nerve
Title: PPARδ preserves a high resistance to fatigue in the mouse medial gastrocnemius after spinal cord transection.
Volume: 53
Issue: 2
Pages: 287-96
Publication
First Author: Buroker NE
Year: 2012
Journal: Protein J
Title: The adaptor-related protein complex 2, alpha 2 subunit (AP2α2) gene is a peroxisome proliferator-activated receptor cardiac target gene.
Volume: 31
Issue: 1
Pages: 75-83
Publication
First Author: Tian Y
Year: 2016
Journal: Glycoconj J
Title: Age-dependent PPARα activation induces hepatic sulfatide accumulation in transgenic mice carrying the hepatitis C virus core gene.
Volume: 33
Issue: 6
Pages: 927-936