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Search results 401 to 500 out of 505 for Prmt1

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1818724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1818724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440907
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440947
Age: embryonic day 16.5
Specimen Label: 2D
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4440905
Assay Type: Immunohistochemistry
Annotation Date: 2010-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4440948
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
Protein
Organism: Mus musculus/domesticus
Length: 371  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 353  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 343  
Fragment?: false
Publication
First Author: Tang J
Year: 1998
Journal: J Biol Chem
Title: PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation.
Volume: 273
Issue: 27
Pages: 16935-45
UniProt Feature
Begin: 291
Description: Asymmetric dimethylarginine; by PRMT1 and PRMT5
Type: modified residue
End: 291
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Allele
Name: protein arginine N-methyltransferase 1; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Protein
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
Publication
First Author: Takai H
Year: 2014
Journal: Cell Rep
Title: 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
Volume: 9
Issue: 1
Pages: 48-60
Publication
First Author: Lai Y
Year: 2017
Journal: J Cell Sci
Title: Lipopolysaccharide modulates p300 and Sirt1 to promote PRMT1 stability via an SCFFbxl17-recognized acetyldegron.
Volume: 130
Issue: 20
Pages: 3578-3587
Publication
First Author: Zhang X
Year: 2003
Journal: Structure
Title: Structure of the predominant protein arginine methyltransferase PRMT1 and analysis of its binding to substrate peptides.
Volume: 11
Issue: 5
Pages: 509-20
Publication
First Author: Kleinschmidt MA
Year: 2008
Journal: Nucleic Acids Res
Title: The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation.
Volume: 36
Issue: 10
Pages: 3202-13
Publication
First Author: Jobert L
Year: 2009
Journal: Exp Cell Res
Title: PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function.
Volume: 315
Issue: 7
Pages: 1273-86
Publication
First Author: Lei NZ
Year: 2009
Journal: Nucleic Acids Res
Title: A feedback regulatory loop between methyltransferase PRMT1 and orphan receptor TR3.
Volume: 37
Issue: 3
Pages: 832-48
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Publication
First Author: Zullo AJ
Year: 2009
Journal: J Biol Chem
Title: Identification of the small protein rich in arginine and glycine (SRAG): a newly identified nucleolar protein that can regulate cell proliferation.
Volume: 284
Issue: 18
Pages: 12504-11
Publication
First Author: van Dijk TB
Year: 2010
Journal: Blood
Title: Fetal globin expression is regulated by Friend of Prmt1.
Volume: 116
Issue: 20
Pages: 4349-52
Publication
First Author: Bhattacharjee R
Year: 2024
Journal: Nat Commun
Title: Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment.
Volume: 15
Issue: 1
Pages: 1210
Publication
First Author: Fanis P
Year: 2012
Journal: Mol Cell Proteomics
Title: Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.
Volume: 11
Issue: 11
Pages: 1263-73
Publication
First Author: Liu C
Year: 2015
Journal: Oncol Lett
Title: BTG1 potentiates apoptosis and suppresses proliferation in renal cell carcinoma by interacting with PRMT1.
Volume: 10
Issue: 2
Pages: 619-624
Publication
First Author: Ceccarelli M
Year: 2015
Journal: Dev Biol
Title: Altered cerebellum development and impaired motor coordination in mice lacking the Btg1 gene: Involvement of cyclin D1.
Volume: 408
Issue: 1
Pages: 109-25
Protein Domain
Type: Family
Description: BTG1 is a member of the BTG/Tob family. It regulates cell cycle progression, inhibits proliferation, promotes apoptosis and stimulates cellular differentiation in multiple cell types. It may inhibit cell growth and promote apoptosis by interacting with PRMT1 (protein arginine N-methyltransferase 1) in renal cell carcinoma []. In mice, it plays a critical role for cerebellar maturation and function [].The BTG/Tob family members contain an conserved N-terminal domain, known as APRO domain (AntiPROliferative) or BTG domain. In mammals, six family members have been identified: BTG1, BTG2/PC3/Tis21, BTG3/ANA, BTG4/PC3B, Tob1/Tob and Tob2. They interact with CAF1, a subunit of the CCR4-NOT complex. They display antiproliferative properties as their ectopic expression in a variety of cell lines reduced cell proliferation [].
Publication
First Author: Ganesh L
Year: 2006
Journal: Mol Cell Biol
Title: Protein methyltransferase 2 inhibits NF-kappaB function and promotes apoptosis.
Volume: 26
Issue: 10
Pages: 3864-74
Publication
First Author: Yang Y
Year: 2010
Journal: Mol Cell
Title: TDRD3 is an effector molecule for arginine-methylated histone marks.
Volume: 40
Issue: 6
Pages: 1016-23
Publication
First Author: Hassa PO
Year: 2008
Journal: J Mol Biol
Title: Protein arginine methyltransferase 1 coactivates NF-kappaB-dependent gene expression synergistically with CARM1 and PARP1.
Volume: 377
Issue: 3
Pages: 668-78
Publication
First Author: Siriboonpiputtana T
Year: 2017
Journal: EMBO J
Title: Transcriptional memory of cells of origin overrides β-catenin requirement of MLL cancer stem cells.
Volume: 36
Issue: 21
Pages: 3139-3155
Publication
First Author: Ikenaka K
Year: 2006
Journal: Neuroscience
Title: Immunohistochemical and western analyses of protein arginine N-methyltransferase 3 in the mouse brain.
Volume: 141
Issue: 4
Pages: 1971-82
Publication
First Author: Bots M
Year: 2014
Journal: Blood
Title: Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors.
Volume: 123
Issue: 9
Pages: 1341-52
Publication
First Author: Solari C
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Protein arginine Methyltransferase 8 gene is expressed in pluripotent stem cells and its expression is modulated by the transcription factor Sox2.
Volume: 473
Issue: 1
Pages: 194-199
Publication
First Author: Antal CE
Year: 2023
Journal: Nat Commun
Title: A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer.
Volume: 14
Issue: 1
Pages: 5195
Publication  
First Author: Wu C
Year: 2023
Journal: Front Mol Neurosci
Title: Cingulate protein arginine methyltransferases 1 regulates peripheral hypersensitivity via fragile X messenger ribonucleoprotein.
Volume: 16
Pages: 1153870
Publication
First Author: Baumeister P
Year: 2005
Journal: Mol Cell Biol
Title: Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers.
Volume: 25
Issue: 11
Pages: 4529-40
Publication
First Author: Yu Z
Year: 2012
Journal: Cell Res
Title: The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.
Volume: 22
Issue: 2
Pages: 305-20
Publication
First Author: Tang J
Year: 2000
Journal: J Biol Chem
Title: Protein-arginine methyltransferase I, the predominant protein-arginine methyltransferase in cells, interacts with and is regulated by interleukin enhancer-binding factor 3.
Volume: 275
Issue: 26
Pages: 19866-76
Publication
First Author: Wang YC
Year: 2012
Journal: FEBS J
Title: Evolutionarily conserved protein arginine methyltransferases in non-mammalian animal systems.
Volume: 279
Issue: 6
Pages: 932-45
Publication
First Author: Tikhanovich I
Year: 2015
Journal: J Biol Chem
Title: Dynamic Arginine Methylation of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 Regulates Toll-like Receptor Signaling.
Volume: 290
Issue: 36
Pages: 22236-49
Publication
First Author: Zhu Y
Year: 2019
Journal: Blood
Title: Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia.
Volume: 134
Issue: 15
Pages: 1257-1268
Publication
First Author: Martinez-Mayer J
Year: 2024
Journal: Genome Med
Title: Knockout mice with pituitary malformations help identify human cases of hypopituitarism.
Volume: 16
Issue: 1
Pages: 75
Publication
First Author: Geyer SH
Year: 2017
Journal: J Anat
Title: A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5).
Volume: 230
Issue: 5
Pages: 710-719
Publication  
First Author: Wilson R
Year: 2016
Journal: Wellcome Open Res
Title: Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice.
Volume: 1
Pages: 1
Protein
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
Publication
First Author: Zhang Z
Year: 2021
Journal: FASEB J
Title: CDKN2A deregulation in fatty liver disease and its accelerative role in the process of lipogenesis.
Volume: 35
Issue: 4
Pages: e21230
Publication
First Author: Ljubicic V
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle.
Volume: 302
Issue: 1
Pages: C110-21
Publication
First Author: Cheng SL
Year: 2015
Journal: Circ Res
Title: Vascular smooth muscle LRP6 limits arteriosclerotic calcification in diabetic LDLR-/- mice by restraining noncanonical Wnt signals.
Volume: 117
Issue: 2
Pages: 142-56
Publication
First Author: Ng RK
Year: 2014
Journal: J Pathol
Title: Epigenetic dysregulation of leukaemic HOX code in MLL-rearranged leukaemia mouse model.
Volume: 232
Issue: 1
Pages: 65-74
Publication  
First Author: Vallée M
Year: 2006
Journal: BMC Genomics
Title: Cross-species hybridizations on a multi-species cDNA microarray to identify evolutionarily conserved genes expressed in oocytes.
Volume: 7
Pages: 113
Publication      
First Author: Mouse Genome Informatics and the Consortium: Deciphering the Mechanisms of Developmental Disorders (DMDD)
Year: 2017
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Deciphering the Mechanisms of Developmental Disorders (DMDD)
Publication
First Author: Perez-Garcia V
Year: 2018
Journal: Nature
Title: Placentation defects are highly prevalent in embryonic lethal mouse mutants.
Volume: 555
Issue: 7697
Pages: 463-468
Publication
First Author: Winkler GS
Year: 2010
Journal: J Cell Physiol
Title: The mammalian anti-proliferative BTG/Tob protein family.
Volume: 222
Issue: 1
Pages: 66-72
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly