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Search results 401 to 500 out of 689 for Ptpn11

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Type Details Score
Publication
37846866 | J:358282
   
First Author: Kaneko K
Year: 2023
Journal: Elife
Title: Identification of CD133(+) intercellsomes in intercellular communication to offset intracellular signal deficit.
Volume: 12
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30837304 | J:284319
 
First Author: Ryu HH
Year: 2019
Journal: Sci Signal
Title: Excitatory neuron-specific SHP2-ERK signaling network regulates synaptic plasticity and memory.
Volume: 12
Issue: 571
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Publication
19001090 | J:144767
First Author: Princen F
Year: 2009
Journal: Mol Cell Biol
Title: Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature death.
Volume: 29
Issue: 2
Pages: 378-88
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Publication
15699129 | J:96557
First Author: Okazawa H
Year: 2005
Journal: J Immunol
Title: Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system.
Volume: 174
Issue: 4
Pages: 2004-11
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Publication
30376595 | J:270196
First Author: Gagné-Sansfacon J
Year: 2019
Journal: J Pathol
Title: The tyrosine phosphatase Shp-2 confers resistance to colonic inflammation by driving goblet cell function and crypt regeneration.
Volume: 247
Issue: 1
Pages: 135-146
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Publication
22759635 | J:185343
First Author: Huang H
Year: 2012
Journal: Genes Dev
Title: A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation.
Volume: 26
Issue: 14
Pages: 1587-601
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Publication
30102570 | J:283321
First Author: Zhang J
Year: 2019
Journal: FASEB J
Title: SHP2 protects endothelial cell barrier through suppressing VE-cadherin internalization regulated by MET-ARF1.
Volume: 33
Issue: 1
Pages: 1124-1137
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Publication
18378677 | J:137570
First Author: Eminaga S
Year: 2008
Journal: J Biol Chem
Title: Noonan syndrome-associated SHP-2/Ptpn11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated ERK activation.
Volume: 283
Issue: 22
Pages: 15328-38
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Publication
29255148 | J:257673
First Author: Guo W
Year: 2017
Journal: Nat Commun
Title: Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis.
Volume: 8
Issue: 1
Pages: 2168
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Publication
20160350 | J:158568
First Author: Banno R
Year: 2010
Journal: J Clin Invest
Title: PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.
Volume: 120
Issue: 3
Pages: 720-34
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Publication
12611902 | J:83590
First Author: Burkart A
Year: 2003
Journal: J Biol Chem
Title: Regulation of the SHP-2 tyrosine phosphatase by a novel cholesterol- and cell confluence-dependent mechanism.
Volume: 278
Issue: 20
Pages: 18360-7
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Publication
8183548 | J:18769
First Author: Feng GS
Year: 1994
Journal: Oncogene
Title: Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.
Volume: 9
Issue: 6
Pages: 1545-50
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Publication
14967925 | J:88403
First Author: Hara KT
Year: 2003
Journal: J Reprod Dev
Title: Dynamic changes in the expression of protein tyrosine phosphatases during preimplantation mouse development: semi-quantification by real-time PCR.
Volume: 49
Issue: 4
Pages: 323-8
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Publication
15169898 | J:91029
First Author: Kontaridis MI
Year: 2004
Journal: Mol Cell Biol
Title: SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway.
Volume: 24
Issue: 12
Pages: 5340-52
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Publication
16873377 | J:117169
First Author: Yu M
Year: 2006
Journal: J Biol Chem
Title: The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway.
Volume: 281
Issue: 39
Pages: 28615-26
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Publication
17369354 | J:120137
First Author: Amin AR
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: SHP-2 tyrosine phosphatase inhibits p73-dependent apoptosis and expression of a subset of p53 target genes induced by EGCG.
Volume: 104
Issue: 13
Pages: 5419-24
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Publication
16731527 | J:116450
First Author: Udell CM
Year: 2006
Journal: J Biol Chem
Title: Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation.
Volume: 281
Issue: 30
Pages: 20949-57
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23374343 | J:193456
First Author: Chen W
Year: 2013
Journal: Cell
Title: Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation.
Volume: 152
Issue: 3
Pages: 467-78
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20526344 | J:161854
First Author: Hitomi K
Year: 2010
Journal: Nat Immunol
Title: An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions.
Volume: 11
Issue: 7
Pages: 601-7
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10521483 | J:200516
First Author: Jones N
Year: 1999
Journal: J Biol Chem
Title: Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration.
Volume: 274
Issue: 43
Pages: 30896-905
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Publication
23112346 | J:201266
First Author: Mazharian A
Year: 2012
Journal: Sci Signal
Title: Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function.
Volume: 5
Issue: 248
Pages: ra78
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12796776 | J:84084
First Author: Watanabe N
Year: 2003
Journal: Nat Immunol
Title: BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.
Volume: 4
Issue: 7
Pages: 670-9
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15568026 | J:94873
First Author: Sedy JR
Year: 2005
Journal: Nat Immunol
Title: B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator.
Volume: 6
Issue: 1
Pages: 90-8
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17239631 | J:118322
First Author: Park-Min KH
Year: 2007
Journal: Immunity
Title: FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin.
Volume: 26
Issue: 1
Pages: 67-78
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31204070 | J:282651
First Author: Mintz MA
Year: 2019
Journal: Immunity
Title: The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis.
Volume: 51
Issue: 2
Pages: 310-323.e7
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22522491 | J:186456
First Author: Xu S
Year: 2012
Journal: Nat Immunol
Title: Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps-SHP-2 pathway.
Volume: 13
Issue: 6
Pages: 551-9
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Publication
25915733 | J:232837
First Author: Deng Z
Year: 2015
Journal: Nat Immunol
Title: Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses.
Volume: 16
Issue: 6
Pages: 642-52
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Publication
30526882 | J:271404
First Author: Cai Z
Year: 2018
Journal: Cell Stem Cell
Title: Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.
Volume: 23
Issue: 6
Pages: 833-849.e5
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21364532 | J:171253
First Author: Fujita Y
Year: 2011
Journal: EMBO J
Title: Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activity.
Volume: 30
Issue: 7
Pages: 1389-401
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Publication
26416283 | J:243470
First Author: Xiao Y
Year: 2015
Journal: J Immunol
Title: Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation.
Volume: 195
Issue: 9
Pages: 4218-27
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Publication
20435932 | J:161224
First Author: Zheng Y
Year: 2010
Journal: J Immunol
Title: Scaffolding adaptor protein Gab1 is required for TLR3/4- and RIG-I-mediated production of proinflammatory cytokines and type I IFN in macrophages.
Volume: 184
Issue: 11
Pages: 6447-56
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28344320 | J:249417
First Author: O'Leary HA
Year: 2017
Journal: Leukemia
Title: DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms.
Volume: 31
Issue: 11
Pages: 2468-2478
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Publication
12937170 | J:86382
First Author: Yuan L
Year: 2003
Journal: J Biol Chem
Title: DNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase.
Volume: 278
Issue: 44
Pages: 42812-20
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Publication
22576369 | J:241280
 
First Author: Sala V
Year: 2012
Journal: Mol Med
Title: Signaling to cardiac hypertrophy: insights from human and mouse RASopathies.
Volume: 18
Pages: 938-47
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11895767 | J:75835
First Author: Yu WM
Year: 2002
Journal: Blood
Title: Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration.
Volume: 99
Issue: 7
Pages: 2351-9
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Publication
18827006 | J:140959
First Author: Mitra S
Year: 2008
Journal: J Cell Sci
Title: SHP-2 is a novel target of Abl kinases during cell proliferation.
Volume: 121
Issue: Pt 20
Pages: 3335-46
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Publication
17954568 | J:126125
First Author: Kong XN
Year: 2007
Journal: J Exp Med
Title: LPS-induced down-regulation of signal regulatory protein {alpha} contributes to innate immune activation in macrophages.
Volume: 204
Issue: 11
Pages: 2719-31
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Publication
11832424 | J:75523
First Author: Sorenson CM
Year: 2002
Journal: Am J Physiol Renal Physiol
Title: Altered regulation of SHP-2 and PTP 1B tyrosine phosphatases in cystic kidneys from bcl-2 -/- mice.
Volume: 282
Issue: 3
Pages: F442-50
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Publication
15677447 | J:98567
First Author: Novotny-Diermayr V
Year: 2005
Journal: J Biol Chem
Title: Modulation of the interleukin-6 receptor subunit glycoprotein 130 complex and its signaling by LMO4 interaction.
Volume: 280
Issue: 13
Pages: 12747-57
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Publication
11970986 | J:112147
First Author: Ott VL
Year: 2002
Journal: J Immunol
Title: Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling.
Volume: 168
Issue: 9
Pages: 4430-9
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Publication
19287004 | J:149742
First Author: Yu L
Year: 2009
Journal: J Biol Chem
Title: JAK2 and SHP2 reciprocally regulate tyrosine phosphorylation and stability of proapoptotic protein ASK1.
Volume: 284
Issue: 20
Pages: 13481-8
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Publication
19542364 | J:151510
First Author: Tsai CC
Year: 2009
Journal: J Immunol
Title: Glycogen synthase kinase-3beta facilitates IFN-gamma-induced STAT1 activation by regulating Src homology-2 domain-containing phosphatase 2.
Volume: 183
Issue: 2
Pages: 856-64
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Publication
19587381 | J:152228
First Author: Jack GD
Year: 2009
Journal: Blood
Title: M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.
Volume: 114
Issue: 10
Pages: 2172-80
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Publication
20421975 | J:160140
First Author: Kim DJ
Year: 2010
Journal: PLoS One
Title: Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation.
Volume: 5
Issue: 4
Pages: e10290
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Publication
20846526 | J:164659
First Author: Cha Y
Year: 2010
Journal: FEBS Lett
Title: SHP2 is a downstream target of ZAP70 to regulate JAK1/STAT3 and ERK signaling pathways in mouse embryonic stem cells.
Volume: 584
Issue: 19
Pages: 4241-6
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Publication
27861634 | J:251516
First Author: Yasui T
Year: 2016
Journal: PLoS One
Title: Molecular Characterization of Striated Muscle-Specific Gab1 Isoform as a Critical Signal Transducer for Neuregulin-1/ErbB Signaling in Cardiomyocytes.
Volume: 11
Issue: 11
Pages: e0166710
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17213291 | J:145327
First Author: Wilson TJ
Year: 2007
Journal: Blood
Title: FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection.
Volume: 109
Issue: 9
Pages: 3786-93
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24590274 | J:209628
First Author: Brouillard P
Year: 2014
Journal: J Clin Invest
Title: Genetics of lymphatic anomalies.
Volume: 124
Issue: 3
Pages: 898-904
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Publication
38924432 | J:350494
First Author: Perrin S
Year: 2024
Journal: Sci Transl Med
Title: MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells.
Volume: 16
Issue: 753
Pages: eadj1597
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Publication
24493648 | J:207470
First Author: Sheean ME
Year: 2014
Journal: Genes Dev
Title: Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Volume: 28
Issue: 3
Pages: 290-303
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15569927 | J:94724
First Author: Gotoh N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina.
Volume: 101
Issue: 49
Pages: 17144-9
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Publication
22015719 | J:178713
First Author: Willecke R
Year: 2011
Journal: Dev Biol
Title: The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney.
Volume: 360
Issue: 2
Pages: 310-7
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16239343 | J:102930
First Author: Yamamoto S
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells.
Volume: 102
Issue: 44
Pages: 15983-8
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23452850 | J:206901
First Author: Findlay GM
Year: 2013
Journal: Cell
Title: Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.
Volume: 152
Issue: 5
Pages: 1008-20
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12893283 | J:84951
First Author: Kumagai H
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells.
Volume: 307
Issue: 3
Pages: 719-29
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15062102 | J:90089
First Author: Ballif BA
Year: 2004
Journal: Curr Biol
Title: Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons.
Volume: 14
Issue: 7
Pages: 606-10
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23321074 | J:198116
First Author: Lee KY
Year: 2013
Journal: Diabetes
Title: Lessons on conditional gene targeting in mouse adipose tissue.
Volume: 62
Issue: 3
Pages: 864-74
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28983104 | J:255705
First Author: Wang L
Year: 2017
Journal: Sci Rep
Title: SHP2 Regulates the Osteogenic Fate of Growth Plate Hypertrophic Chondrocytes.
Volume: 7
Issue: 1
Pages: 12699
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18077586 | J:130571
First Author: Pan Y
Year: 2008
Journal: Development
Title: Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction.
Volume: 135
Issue: 2
Pages: 301-10
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17646384 | J:126547
First Author: Ke Y
Year: 2007
Journal: Mol Cell Biol
Title: Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality.
Volume: 27
Issue: 19
Pages: 6706-17
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20648636 | J:168041
First Author: Zhu Y
Year: 2010
Journal: Glia
Title: Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase.
Volume: 58
Issue: 12
Pages: 1407-14
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35260907 | J:324721
 
First Author: Fang Y
Year: 2022
Journal: J Cell Sci
Title: SIRT1 regulates cardiomyocyte alignment during maturation.
Volume: 135
Issue: 7
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12808090 | J:83953
First Author: Holgado-Madruga M
Year: 2003
Journal: Mol Cell Biol
Title: Gab1 is an integrator of cell death versus cell survival signals in oxidative stress.
Volume: 23
Issue: 13
Pages: 4471-84
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25377219 | J:230303
First Author: Meng Q
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Eyelid closure in embryogenesis is required for ocular adnexa development.
Volume: 55
Issue: 11
Pages: 7652-61
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17804806 | J:124878
First Author: Sierro F
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.
Volume: 104
Issue: 37
Pages: 14759-64
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12971893 | J:85573
First Author: Williams SE
Year: 2003
Journal: Neuron
Title: Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm.
Volume: 39
Issue: 6
Pages: 919-35
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8875997 | J:36011
First Author: Huang K
Year: 1996
Journal: Oncogene
Title: Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.
Volume: 13
Issue: 7
Pages: 1567-73
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15723811 | J:96676
First Author: Zhang H
Year: 2005
Journal: Immunity
Title: The Src family kinases Hck and Fgr negatively regulate neutrophil and dendritic cell chemokine signaling via PIR-B.
Volume: 22
Issue: 2
Pages: 235-46
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17881575 | J:125303
First Author: Schaeper U
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Volume: 104
Issue: 39
Pages: 15376-81
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19805360 | J:153219
First Author: Grossmann KS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development.
Volume: 106
Issue: 39
Pages: 16704-9
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20884876 | J:182094
First Author: Huang ZP
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects.
Volume: 30
Issue: 12
Pages: 2575-86
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20215346 | J:158679
First Author: Pan Y
Year: 2010
Journal: Development
Title: Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development.
Volume: 137
Issue: 7
Pages: 1085-93
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27799550 | J:283483
First Author: Mathew G
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor.
Volume: 113
Issue: 46
Pages: 13156-13161
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28424251 | J:242229
First Author: Ran H
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase.
Volume: 114
Issue: 18
Pages: 4816-4821
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17082620 | J:116665
First Author: Yu X
Year: 2006
Journal: J Immunol
Title: Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.
Volume: 177
Issue: 10
Pages: 7042-9
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23349485 | J:208570
First Author: Lee KM
Year: 2013
Journal: Diabetes
Title: Disruption of the cereblon gene enhances hepatic AMPK activity and prevents high-fat diet-induced obesity and insulin resistance in mice.
Volume: 62
Issue: 6
Pages: 1855-64
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19727691 | J:157883
First Author: Reinhard J
Year: 2009
Journal: Exp Brain Res
Title: Protein tyrosine phosphatases expression during development of mouse superior colliculus.
Volume: 199
Issue: 3-4
Pages: 279-97
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27578777 | J:237345
First Author: Dee A
Year: 2016
Journal: Development
Title: Regulation of self-renewing neural progenitors by FGF/ERK signaling controls formation of the inferior colliculus.
Volume: 143
Issue: 20
Pages: 3661-3673
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27348588 | J:237131
First Author: Lauriol J
Year: 2016
Journal: J Clin Invest
Title: Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines.
Volume: 126
Issue: 8
Pages: 2989-3005
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21576358 | J:174095
First Author: Cai Z
Year: 2011
Journal: Mol Cell Biol
Title: Loss of Shp2-mediated mitogen-activated protein kinase signaling in Muller glial cells results in retinal degeneration.
Volume: 31
Issue: 14
Pages: 2973-83
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Publication
27974211 | J:241708
First Author: Luo X
Year: 2016
Journal: Cell Rep
Title: Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells.
Volume: 17
Issue: 11
Pages: 2979-2993
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Publication
26100917 | J:226941
First Author: Akerberg BN
Year: 2015
Journal: Dev Biol
Title: Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease.
Volume: 407
Issue: 1
Pages: 158-72
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24284065 | J:310318
First Author: Li H
Year: 2014
Journal: J Cell Sci
Title: Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development.
Volume: 127
Issue: Pt 3
Pages: 571-82
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Publication
20237281 | J:159104
First Author: Cai Z
Year: 2010
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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