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Search results 401 to 500 out of 3113 for Rac1

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Type Details Score
Publication
First Author: Rosselot AE
Year: 2022
Journal: EMBO J
Title: Ontogeny and function of the circadian clock in intestinal organoids.
Volume: 41
Issue: 2
Pages: e106973
Publication
First Author: Fabbiano S
Year: 2014
Journal: Mol Cell Biol
Title: Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells.
Volume: 34
Issue: 24
Pages: 4404-19
Publication
First Author: Ni L
Year: 2022
Journal: J Am Heart Assoc
Title: Pyruvate Kinase M2 Protects Heart from Pressure Overload-Induced Heart Failure by Phosphorylating RAC1.
Volume: 11
Issue: 11
Pages: e024854
Publication
First Author: Ji P
Year: 2008
Journal: Nat Cell Biol
Title: Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2.
Volume: 10
Issue: 3
Pages: 314-21
Publication
First Author: Shintani Y
Year: 2006
Journal: Mol Biol Cell
Title: Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells.
Volume: 17
Issue: 7
Pages: 2963-75
Publication
First Author: Mahoney CM
Year: 2009
Journal: J Biol Chem
Title: Therapeutic ultrasound bypasses canonical syndecan-4 signaling to activate rac1.
Volume: 284
Issue: 13
Pages: 8898-909
Publication
First Author: Machacek M
Year: 2009
Journal: Nature
Title: Coordination of Rho GTPase activities during cell protrusion.
Volume: 461
Issue: 7260
Pages: 99-103
Publication
First Author: Bosco EE
Year: 2010
Journal: Oncogene
Title: NF2-deficient cells depend on the Rac1-canonical Wnt signaling pathway to promote the loss of contact inhibition of proliferation.
Volume: 29
Issue: 17
Pages: 2540-9
Publication
First Author: Lee SI
Year: 2013
Journal: J Neurosci
Title: Atypical protein kinase C and Par3 are required for proteoglycan-induced axon growth inhibition.
Volume: 33
Issue: 6
Pages: 2541-54
Publication
First Author: Gu J
Year: 2020
Journal: Exp Cell Res
Title: Rho-GEF trio regulates osteoclast differentiation and function by Rac1/Cdc42.
Volume: 396
Issue: 1
Pages: 112265
Publication
First Author: Čajánek L
Year: 2013
Journal: Mol Cell Biol
Title: Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons.
Volume: 33
Issue: 1
Pages: 59-70
Publication
First Author: Danelon V
Year: 2020
Journal: J Neurosci
Title: Modular and Distinct Plexin-A4/FARP2/Rac1 Signaling Controls Dendrite Morphogenesis.
Volume: 40
Issue: 28
Pages: 5413-5430
Publication  
First Author: Su Q
Year: 2019
Journal: J Mol Cell Cardiol
Title: Inhibition of lncRNA TUG1 upregulates miR-142-3p to ameliorate myocardial injury during ischemia and reperfusion via targeting HMGB1- and Rac1-induced autophagy.
Volume: 133
Pages: 12-25
Publication
First Author: Yu KP
Year: 2007
Journal: J Bone Miner Res
Title: Breast cancer-associated gene 3 (BCA3) is a novel Rac1-interacting protein.
Volume: 22
Issue: 4
Pages: 628-37
Publication
First Author: Backer S
Year: 2007
Journal: J Neurosci
Title: Trio controls the mature organization of neuronal clusters in the hindbrain.
Volume: 27
Issue: 39
Pages: 10323-32
Publication
First Author: Camerer E
Year: 2010
Journal: Dev Cell
Title: Local protease signaling contributes to neural tube closure in the mouse embryo.
Volume: 18
Issue: 1
Pages: 25-38
Publication
First Author: Löf-Öhlin ZM
Year: 2017
Journal: Nat Cell Biol
Title: EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity.
Volume: 19
Issue: 11
Pages: 1313-1325
Publication
First Author: Fuchs S
Year: 2009
Journal: Cell Stem Cell
Title: Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.
Volume: 4
Issue: 3
Pages: 236-47
Publication
First Author: Cheung EC
Year: 2016
Journal: Genes Dev
Title: Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine.
Volume: 30
Issue: 1
Pages: 52-63
Publication
First Author: Kogler M
Year: 2020
Journal: Cancer Res
Title: HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
Volume: 80
Issue: 14
Pages: 3009-3022
Publication
First Author: Henderson RB
Year: 2010
Journal: J Exp Med
Title: A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival.
Volume: 207
Issue: 4
Pages: 837-53
Publication
First Author: Lawson CD
Year: 2011
Journal: J Immunol
Title: P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses.
Volume: 186
Issue: 3
Pages: 1467-76
Publication
First Author: Mondal S
Year: 2011
Journal: J Immunol
Title: PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase.
Volume: 187
Issue: 11
Pages: 5783-94
Publication
First Author: Zhang T
Year: 2012
Journal: Cardiovasc Res
Title: Mitogen-activated protein kinase phosphatase-1 inhibits myocardial TNF-α expression and improves cardiac function during endotoxemia.
Volume: 93
Issue: 3
Pages: 471-9
Publication
First Author: Hedrick NG
Year: 2016
Journal: Nature
Title: Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity.
Volume: 538
Issue: 7623
Pages: 104-108
Publication    
First Author: O'Neil SD
Year: 2021
Journal: Elife
Title: Action potential-coupled Rho GTPase signaling drives presynaptic plasticity.
Volume: 10
Publication
First Author: Zeng C
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 Small GTPase phosphorylation and activation.
Volume: 311
Issue: 4
Pages: E772-E780
Publication
First Author: Löffek S
Year: 2014
Journal: PLoS One
Title: Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling.
Volume: 9
Issue: 2
Pages: e87263
Publication
First Author: Sun P
Year: 2003
Journal: J Biol Chem
Title: Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation.
Volume: 278
Issue: 6
Pages: 4063-71
Publication
First Author: Mammoto T
Year: 2007
Journal: J Biol Chem
Title: Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo.
Volume: 282
Issue: 33
Pages: 23910-8
Publication
First Author: Tanabe K
Year: 2003
Journal: J Neurosci
Title: Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth.
Volume: 23
Issue: 29
Pages: 9675-86
Publication
First Author: Kanekura K
Year: 2005
Journal: J Biol Chem
Title: A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death.
Volume: 280
Issue: 6
Pages: 4532-43
Publication
First Author: Toda S
Year: 2012
Journal: Mol Cell Biol
Title: Two-step engulfment of apoptotic cells.
Volume: 32
Issue: 1
Pages: 118-25
Publication
First Author: Utomo A
Year: 2006
Journal: J Immunol
Title: Vav proteins in neutrophils are required for FcgammaR-mediated signaling to Rac GTPases and nicotinamide adenine dinucleotide phosphate oxidase component p40(phox).
Volume: 177
Issue: 9
Pages: 6388-97
Publication  
First Author: Bongmba OY
Year: 2011
Journal: Brain Res
Title: Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology.
Volume: 1399
Pages: 79-95
Publication
First Author: Martin H
Year: 2013
Journal: J Clin Invest
Title: Pak and Rac GTPases promote oncogenic KIT-induced neoplasms.
Volume: 123
Issue: 10
Pages: 4449-63
Publication
First Author: Marcos S
Year: 2009
Journal: PLoS One
Title: Tubulin tyrosination is required for the proper organization and pathfinding of the growth cone.
Volume: 4
Issue: 4
Pages: e5405
Publication
First Author: Wang L
Year: 2006
Journal: Blood
Title: Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment.
Volume: 107
Issue: 1
Pages: 98-105
Publication
First Author: Gomes SZ
Year: 2012
Journal: Biol Reprod
Title: Expression of NADPH oxidase by trophoblast cells: potential implications for the postimplanting mouse embryo.
Volume: 86
Issue: 2
Pages: 56
Publication
First Author: Chen CM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice.
Volume: 114
Issue: 4
Pages: E619-E628
Publication
First Author: Abou-Kheir W
Year: 2008
Journal: J Cell Sci
Title: Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.
Volume: 121
Issue: Pt 3
Pages: 379-90
Publication
First Author: Schweer J
Year: 2013
Journal: PLoS Pathog
Title: The cytotoxic necrotizing factor of Yersinia pseudotuberculosis (CNFY) enhances inflammation and Yop delivery during infection by activation of Rho GTPases.
Volume: 9
Issue: 11
Pages: e1003746
Publication
First Author: López-Posadas R
Year: 2019
Journal: Gastroenterology
Title: Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice.
Volume: 157
Issue: 5
Pages: 1293-1309
Publication
First Author: Miyamoto Y
Year: 2013
Journal: Sci Signal
Title: Akt and PP2A reciprocally regulate the guanine nucleotide exchange factor Dock6 to control axon growth of sensory neurons.
Volume: 6
Issue: 265
Pages: ra15
Publication
First Author: Wen Q
Year: 2022
Journal: Brain
Title: Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human.
Volume: 145
Issue: 2
Pages: 670-683
Publication
First Author: Nishimura S
Year: 2012
Journal: Blood
Title: In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling.
Volume: 119
Issue: 8
Pages: e45-56
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Publication
First Author: Bellchambers HM
Year: 2021
Journal: Hum Mol Genet
Title: Loss of Zic3 impairs planar cell polarity leading to abnormal left-right signaling, heart defects and neural tube defects.
Volume: 30
Issue: 24
Pages: 2402-2415
Publication
First Author: Tivodar S
Year: 2015
Journal: Cereb Cortex
Title: Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons.
Volume: 25
Issue: 9
Pages: 2370-82
Publication
First Author: Vidaki M
Year: 2012
Journal: Cereb Cortex
Title: Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex.
Volume: 22
Issue: 3
Pages: 680-92
Publication
First Author: Fan M
Year: 2022
Journal: Biol Psychiatry
Title: JADE2 Is Essential for Hippocampal Synaptic Plasticity and Cognitive Functions in Mice.
Volume: 92
Issue: 10
Pages: 800-814
Publication
First Author: Aoki K
Year: 2005
Journal: Mol Biol Cell
Title: Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells.
Volume: 16
Issue: 5
Pages: 2207-17
Publication
First Author: Gavard J
Year: 2004
Journal: J Cell Sci
Title: Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways.
Volume: 117
Issue: Pt 2
Pages: 257-70
Publication  
First Author: Zhu C
Year: 2018
Journal: Front Mol Neurosci
Title: Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice.
Volume: 11
Pages: 362
Publication  
First Author: Johansson A
Year: 2000
Journal: J Cell Sci
Title: The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1.
Volume: 113 ( Pt 18)
Pages: 3267-75
Publication
First Author: Ramgolam VS
Year: 2010
Journal: PLoS One
Title: T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascade.
Volume: 5
Issue: 12
Pages: e14450
Publication  
First Author: Mitchell DC
Year: 2007
Journal: Mol Vis
Title: Developmental expression of three small GTPases in the mouse eye.
Volume: 13
Pages: 1144-53
Publication
First Author: Jiang XS
Year: 2010
Journal: Hum Mol Genet
Title: Activation of Rho GTPases in Smith-Lemli-Opitz syndrome: pathophysiological and clinical implications.
Volume: 19
Issue: 7
Pages: 1347-57
Publication
First Author: Logan CM
Year: 2017
Journal: Dev Biol
Title: N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis.
Volume: 428
Issue: 1
Pages: 118-134
Publication
First Author: Wei L
Year: 2002
Journal: Development
Title: Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation.
Volume: 129
Issue: 7
Pages: 1705-14
Publication
First Author: Pisko J
Year: 2021
Journal: Sci Rep
Title: Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres.
Volume: 11
Issue: 1
Pages: 9228
Publication
First Author: Migeotte I
Year: 2010
Journal: PLoS Biol
Title: Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse.
Volume: 8
Issue: 8
Pages: e1000442
Publication
First Author: Chislock EM
Year: 2013
Journal: PLoS One
Title: Abl family kinases regulate endothelial barrier function in vitro and in mice.
Volume: 8
Issue: 12
Pages: e85231
Protein Domain
Type: Family
Description: This entry includes CYRI (CYFIP-related Rac interactor) from Dictyostelium and its homologues, CYRIA/CYRIB, from animals. CYRI binds activated Rac1 via a domain of unknown function (DUF1394). It plays important roles in cell migration, chemotaxis and pathogen entry into cells. It controls actin dynamics through Rac1, the Scar/WAVE Complex and the Arp2/3 Complex [, ]. In mice, CYRIB (also known as CYRI or FAM49B) negatively regulates RAC1-driven cytoskeletal remodelling and plays a role in restricting infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes [].
Publication
First Author: Grimsley-Myers CM
Year: 2012
Journal: Dev Biol
Title: Redundant functions of Rac GTPases in inner ear morphogenesis.
Volume: 362
Issue: 2
Pages: 172-86
Publication
First Author: Li D
Year: 2011
Journal: Development
Title: Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis.
Volume: 138
Issue: 2
Pages: 303-15
Publication
First Author: Boczonadi V
Year: 2014
Journal: Cardiovasc Res
Title: Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium.
Volume: 104
Issue: 1
Pages: 103-15
Publication
First Author: Bu F
Year: 2021
Journal: J Neurochem
Title: Activation of neuronal Ras-related C3 botulinum toxin substrate 1 (Rac1) improves post-stroke recovery and axonal plasticity in mice.
Volume: 157
Issue: 4
Pages: 1366-1376
Publication
First Author: Andersson ER
Year: 2008
Journal: PLoS One
Title: Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo.
Volume: 3
Issue: 10
Pages: e3517
Publication
First Author: Joberty G
Year: 2000
Journal: Nat Cell Biol
Title: The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.
Volume: 2
Issue: 8
Pages: 531-9
Publication    
First Author: Collins TN
Year: 2018
Journal: Elife
Title: Crk proteins transduce FGF signaling to promote lens fiber cell elongation.
Volume: 7
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory