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Search results 401 to 500 out of 543 for Rasgrf1

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Type Details Score
Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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HT Experiment
E-GEOD-8425 | Transcription profiling of mouse laser dissected hippocampus of Rasgrf1 knockout mice
Series Id: GSE8425
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
16649990 | -
First Author: Forlani G
Year: 2006
Journal: FEBS J
Title: The guanine nucleotide exchange factor RasGRF1 directly binds microtubules via DHPH2-mediated interaction.
Volume: 273
Issue: 10
Pages: 2127-38
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Allele
Rasgrf1<tm2Pds> | MGI:3611766
 
Name: RAS protein-specific guanine nucleotide-releasing factor 1; targeted mutation 2, Paul D Soloway
Allele Type: Targeted
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Publication
23940355 | J:354404
First Author: Schwechter B
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: RasGRF2 Rac-GEF activity couples NMDA receptor calcium flux to enhanced synaptic transmission.
Volume: 110
Issue: 35
Pages: 14462-7
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Publication
17923690 | J:128985
First Author: Ruiz S
Year: 2007
Journal: Mol Cell Biol
Title: RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses.
Volume: 27
Issue: 23
Pages: 8127-42
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Strain
MGI:6122738 | B6.129S4-Rasgrf1<tm2Pds>/Cnrm
Attribute String: mutant strain, congenic, targeted mutation
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Genotype
Genotype
Symbol: Rasgrf1/Rasgrf1<+>
Background: involves: 129S4/SvJae
Zygosity: ht
Has Mutant Allele: true
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Publication
21382555 | J:174739
First Author: Lee KJ
Year: 2011
Journal: Neuron
Title: Requirement for Plk2 in orchestrated ras and rap signaling, homeostatic structural plasticity, and memory.
Volume: 69
Issue: 5
Pages: 957-73
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Publication
14622581 | J:114138
First Author: Krapivinsky G
Year: 2003
Journal: Neuron
Title: The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.
Volume: 40
Issue: 4
Pages: 775-84
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Protein Coding Gene
MGI:109137 | Rasgrf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0018766 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020811 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020765 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020738 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020761 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020555 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_109137 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020514 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020639 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020619 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020648 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021238 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019826 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020131 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015845 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019650 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
28640817 | J:241918
First Author: Bethge P
Year: 2017
Journal: PLoS One
Title: An R-CaMP1.07 reporter mouse for cell-type-specific expression of a sensitive red fluorescent calcium indicator.
Volume: 12
Issue: 6
Pages: e0179460
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Publication
28009304 | J:241965
First Author: Kim TH
Year: 2016
Journal: Cell Rep
Title: Long-Term Optical Access to an Estimated One Million Neurons in the Live Mouse Cortex.
Volume: 17
Issue: 12
Pages: 3385-3394
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Publication
32238928 | J:293250
First Author: Rumyantsev OI
Year: 2020
Journal: Nature
Title: Fundamental bounds on the fidelity of sensory cortical coding.
Volume: 580
Issue: 7801
Pages: 100-105
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Publication
33159842 | J:300555
First Author: Gallero-Salas Y
Year: 2021
Journal: Neuron
Title: Sensory and Behavioral Components of Neocortical Signal Flow in Discrimination Tasks with Short-Term Memory.
Volume: 109
Issue: 1
Pages: 135-148.e6
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Publication
32884146 | J:296977
First Author: Banerjee A
Year: 2020
Journal: Nature
Title: Value-guided remapping of sensory cortex by lateral orbitofrontal cortex.
Volume: 585
Issue: 7824
Pages: 245-250
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Publication
30100254 | J:328652
First Author: Gilad A
Year: 2018
Journal: Neuron
Title: Behavioral Strategy Determines Frontal or Posterior Location of Short-Term Memory in Neocortex.
Volume: 99
Issue: 4
Pages: 814-828.e7
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Publication
25454123 | J:325814
 
First Author: Easton AC
Year: 2014
Journal: Brain Res Bull
Title: Rasgrf2 controls dopaminergic adaptations to alcohol in mice.
Volume: 109
Pages: 143-50
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Publication
23223532 | J:310517
First Author: Stacey D
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release.
Volume: 109
Issue: 51
Pages: 21128-33
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Publication
- | J:199220
     
First Author: Zeng H
Year: 2013
Journal: MGI Direct Data Submission
Title: Generation of an inducible Rasgrf2-cre knockin allele
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Publication
39392390 | J:358641
   
First Author: Liu Y
Year: 2024
Journal: Elife
Title: Cell class-specific long-range axonal projections of neurons in mouse whisker-related somatosensory cortices.
Volume: 13
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Publication
34878406 | J:324801
   
First Author: Suzuki M
Year: 2021
Journal: Elife
Title: Double-μPeriscope, a tool for multilayer optical recordings, optogenetic stimulations or both.
Volume: 10
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Publication
9027497 | J:37833
First Author: Fam NP
Year: 1997
Journal: Genomics
Title: Mapping of the Ras-GRF2 gene (GRF2) to mouse chromosome 13C3-D1 and human chromosome 5q13, near the Ras-GAP gene.
Volume: 39
Issue: 1
Pages: 118-20
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Publication
37947653 | J:342633
 
First Author: Jimeno D
Year: 2023
Journal: Cells
Title: GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina.
Volume: 12
Issue: 21
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_07
Specimen Label: euxassay_009649_07
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_08
Specimen Label: euxassay_009649_08
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_16
Specimen Label: euxassay_009649_16
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_17
Specimen Label: euxassay_009649_17
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_11
Specimen Label: euxassay_009649_11
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_12
Specimen Label: euxassay_009649_12
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_13
Specimen Label: euxassay_009649_13
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_14
Specimen Label: euxassay_009649_14
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_15
Specimen Label: euxassay_009649_15
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_08
Specimen Label: euxassay_009649_08
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_09
Specimen Label: euxassay_009649_09
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_10
Specimen Label: euxassay_009649_10
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_11
Specimen Label: euxassay_009649_11
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_12
Specimen Label: euxassay_009649_12
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_14
Specimen Label: euxassay_009649_14
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_15
Specimen Label: euxassay_009649_15
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_16
Specimen Label: euxassay_009649_16
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:4423920
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827628
Age: embryonic day 14.5
Image: euxassay_009649_17
Specimen Label: euxassay_009649_17
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:6181935
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191192
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Rasgrf2
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6181935
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191192
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Rasgrf2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6181935
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191192
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Rasgrf2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6181935
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191192
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Rasgrf2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6181935
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191192
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Rasgrf2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6181935
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191192
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Rasgrf2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6181935
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191192
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Rasgrf2
Detected: true
Specimen Num: 7
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Publication
9707409 | -
First Author: Fan WT
Year: 1998
Journal: Curr Biol
Title: The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways.
Volume: 8
Issue: 16
Pages: 935-8
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Publication
24737505 | -
First Author: Easton AC
Year: 2014
Journal: Psychopharmacology (Berl)
Title: Rasgrf2 controls noradrenergic involvement in the acute and subchronic effects of alcohol in the brain.
Volume: 231
Issue: 21
Pages: 4199-209
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Protein Domain
IPR030744 | RasGRF2
Type: Family
Description: RasGRF2 belongs to the RasGRF family. It is a dual Ras/Rac guanine nucleotide exchange factor (GEF) that has been shown to be necessary for long-term potentiation in situ [, ]. It is also involved in T-cell signalling responses through Ras GTPases []. RasGRF2 has been linked to alcoholism [].RasGRF is a Ras family guanine nucleotide exchange factor sharing homology with Saccharomyces cerevisiae Cdc25 that stimulates nucleotide exchange on S. cerevisiae RAS []. RasGRF N-terminal region contains a Dbl homology (DH) domain which is generally present in GEFs for the Rho family of small G proteins, whereas the C-terminal Cdc25-related domain is linked to Ras GTPase signalling []. The presence of regulatory domains for Rho and Ras GTPases implicates the role of RasGRF in the control of the both pathways []. Two RasGRF, RasGRF1 and 2, have been identified in mammals []. Their function can be inhibited by its interaction with Cdc42 in its inactive GDP bound form. Reciprocally, the effects of Cdc42 on cytoskeletal dynamics can be inhibited by RasGRF1/2 [].
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Publication
15199123 | J:91593
First Author: Lewis A
Year: 2004
Journal: Mol Cell Biol
Title: Tandem repeat hypothesis in imprinting: deletion of a conserved direct repeat element upstream of H19 has no effect on imprinting in the Igf2-H19 region.
Volume: 24
Issue: 13
Pages: 5650-6
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