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Search results 401 to 500 out of 511 for Ryk

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST88; Specimen C1577
Specimen Label: ST88; Specimen C1577
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST35; Specimen C1044
Specimen Label: ST35; Specimen C1044
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST88; Specimen C1577
Specimen Label: ST88; Specimen C1577
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3557722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST35; Specimen C1044
Specimen Label: ST35; Specimen C1044
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Specimen Label: ST88; Specimen C1577
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST35; Specimen C1044
Specimen Label: ST35; Specimen C1044
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST88; Specimen C1577
Specimen Label: ST88; Specimen C1577
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST35; Specimen C1044
Specimen Label: ST35; Specimen C1044
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST88; Specimen C1577
Specimen Label: ST88; Specimen C1577
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST35; Specimen C1044
Specimen Label: ST35; Specimen C1044
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Specimen Label: ST88; Specimen C1577
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST35; Specimen C1044
Specimen Label: ST35; Specimen C1044
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST88; Specimen C1577
Specimen Label: ST88; Specimen C1577
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Specimen Label: ST35; Specimen C1044
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Specimen Label: ST88; Specimen C1577
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Specimen Label: ST35; Specimen C1044
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Specimen Label: ST88; Specimen C1577
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1802422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST35; Specimen C1044
Specimen Label: ST35; Specimen C1044
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Specimen Label: ST88; Specimen C1577
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST35; Specimen C1044
Note: Expression was detected in the skull (base and vault).
Specimen Label: ST35; Specimen C1044
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: ST88; Specimen C1577
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST35; Specimen C1044
Note: Expression was strong in whisker follicle.
Specimen Label: ST35; Specimen C1044
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5309591
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420956
Age: embryonic day 14.5
Image: ST88; Specimen C1577
Note: Expression was strong in whisker follicle.
Specimen Label: ST88; Specimen C1577
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6761375
Assay Type: RNA in situ
Annotation Date: 2021-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6761376
Age: embryonic day 15.5
Image: S3A
Specimen Label: S3A
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6761375
Assay Type: RNA in situ
Annotation Date: 2021-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1625524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6761376
Age: embryonic day 16.5
Image: S3B
Specimen Label: S3B
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6761375
Assay Type: RNA in situ
Annotation Date: 2021-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1625526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6761376
Age: embryonic day 18.5
Image: S3C
Specimen Label: S3C
Detected: true
Specimen Num: 8
•
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Publication
29576390 | J:261266
First Author: Sarin S
Year: 2018
Journal: Neuron
Title: Role for Wnt Signaling in Retinal Neuropil Development: Analysis via RNA-Seq and In Vivo Somatic CRISPR Mutagenesis.
Volume: 98
Issue: 1
Pages: 109-126.e8
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•
Publication
15520276 | J:93879
First Author: Matheu A
Year: 2004
Journal: Genes Dev
Title: Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging.
Volume: 18
Issue: 22
Pages: 2736-46
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Publication
2466296 | J:42354
First Author: Wilks AF
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction.
Volume: 86
Issue: 5
Pages: 1603-7
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Publication
8346215 | J:13545
First Author: Biesecker LG
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Identification of four murine cDNAs encoding putative protein kinases from primitive embryonic stem cells differentiated in vitro.
Volume: 90
Issue: 15
Pages: 7044-8
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Publication
3291115 | J:31015
First Author: Hanks SK
Year: 1988
Journal: Science
Title: The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
Volume: 241
Issue: 4861
Pages: 42-52
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Publication
20084116 | J:156864
First Author: Buchert M
Year: 2010
Journal: PLoS Genet
Title: Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.
Volume: 6
Issue: 1
Pages: e1000816
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Publication
21106844 | J:166974
First Author: Fenstermaker AG
Year: 2010
Journal: J Neurosci
Title: Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem.
Volume: 30
Issue: 47
Pages: 16053-64
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Publication
26490861 | J:226687
First Author: Morello F
Year: 2015
Journal: J Neurosci
Title: Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development.
Volume: 35
Issue: 42
Pages: 14205-19
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Publication
30516471 | J:267385
   
First Author: O'Brien LL
Year: 2018
Journal: Elife
Title: Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment.
Volume: 7
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Publication
26921296 | J:244712
First Author: Navarro N
Year: 2016
Journal: G3 (Bethesda)
Title: Does 3D Phenotyping Yield Substantial Insights in the Genetics of the Mouse Mandible Shape?
Volume: 6
Issue: 5
Pages: 1153-63
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Publication
7893599 | J:22208
First Author: Ruiz JC
Year: 1994
Journal: Mech Dev
Title: Identification of novel protein kinases expressed in the myocardium of the developing mouse heart.
Volume: 48
Issue: 3
Pages: 153-64
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Publication
7542761 | J:27414
First Author: Sommers CL
Year: 1995
Journal: Oncogene
Title: Murine txk: a protein tyrosine kinase gene regulated by T cell activation.
Volume: 11
Issue: 2
Pages: 245-51
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Publication
11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
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Publication
18973680 | J:141291
 
First Author: Tamplin OJ
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Volume: 9
Pages: 511
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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•
•
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q01887
Organism: Mus musculus/domesticus
Length: 594  
Fragment?: false
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Protein
H9H9R6
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
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Author
Van Ryk D
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Interaction Experiment
Lyu J (2009)
Description: Cdc37 regulates Ryk signaling by stabilizing the cleaved Ryk intracellular domain.
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Publication
30268766 | J:269377
 
First Author: Arafa SR
Year: 2019
Journal: Exp Neurol
Title: Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth.
Volume: 311
Pages: 125-134
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Publication
31377403 | J:353191
 
First Author: LaSarge CL
Year: 2019
Journal: Exp Neurol
Title: Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?
Volume: 321
Pages: 113029
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Interaction Experiment
Lu W (2004)
Description: Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth.
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Pseudogene
MGI:103028 | Ryk-ps1
Type: pseudogene
Organism: mouse, laboratory
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Publication
33309800 | J:323317
 
First Author: LaSarge CL
Year: 2021
Journal: Prog Neurobiol
Title: mTOR-driven neural circuit changes initiate an epileptogenic cascade.
Volume: 200
Pages: 101974
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Interaction Experiment
Keeble TR (2006)
Description: The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum.
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Publication
19269974 | -
First Author: Lyu J
Year: 2009
Journal: J Biol Chem
Title: Cdc37 regulates Ryk signaling by stabilizing the cleaved Ryk intracellular domain.
Volume: 284
Issue: 19
Pages: 12940-8
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Publication
28855130 | J:258149
 
First Author: Santos VR
Year: 2017
Journal: Neurobiol Dis
Title: PTEN deletion increases hippocampal granule cell excitability in male and female mice.
Volume: 108
Pages: 339-351
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Publication
27681419 | J:239110
First Author: Gross C
Year: 2016
Journal: Cell Rep
Title: MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset.
Volume: 17
Issue: 1
Pages: 37-45
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Publication
38507462 | J:354787
   
First Author: Park C
Year: 2024
Journal: Elife
Title: Murine alveolar macrophages rapidly accumulate intranasally administered SARS-CoV-2 Spike protein leading to neutrophil recruitment and damage.
Volume: 12
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Protein Domain
IPR038677 | WIF_sf
Type: Homologous_superfamily
Description: Wnt morphogens control embryonic development and homeostasis in adult tissues. In vertebrates the N-terminal WIF domain (WIF-1WD) of Wnt inhibitory factor 1 (WIF-1) binds Wnt ligands.This entry represents the WIF domain, it is found in the RYK tyrosine kinase receptors and WIF the Wnt-inhibitory-factor. The domain is extracellular and contains two conserved cysteines that may form a disulphide bridge. This domain is Wnt binding in WIF, and it has been suggested that RYK may also bind to Wnt []. The WIF domain of WIF-1 was suggested to have a function in inhibiting Wnt signalling [].
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Protein Domain
IPR003306 | WIF
Type: Domain
Description: Wnt morphogens control embryonic development and homeostasis in adult tissues. In vertebrates the N-terminal WIF domain (WIF-1WD) of Wnt inhibitory factor 1 (WIF-1) binds Wnt ligands.This entry represents the WIF domain, it is found in the RYK tyrosine kinase receptors and WIF the Wnt-inhibitory-factor. The domain is extracellular and contains two conserved cysteines that may form a disulphide bridge. This domain is Wnt binding in WIF, and it has been suggested that RYK may also bind to Wnt []. The WIF domain of WIF-1 was suggested to have a function in inhibiting Wnt signalling [].
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Publication
10637605 | -
First Author: Patthy L
Year: 2000
Journal: Trends Biochem Sci
Title: The WIF module.
Volume: 25
Issue: 1
Pages: 12-3
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Publication
21743455 | J:245252
First Author: Malinauskas T
Year: 2011
Journal: Nat Struct Mol Biol
Title: Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1.
Volume: 18
Issue: 8
Pages: 886-93
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Publication
38167296 | J:344284
First Author: Yang X
Year: 2024
Journal: Nat Commun
Title: Mcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling.
Volume: 15
Issue: 1
Pages: 36
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Protein
Q9WUA1
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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