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Search results 401 to 500 out of 534 for S1pr1

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Type Details Score
Publication
27063549 | J:252545
 
First Author: Gómez-López S
Year: 2016
Journal: Sci Rep
Title: Neural ablation of the PARK10 candidate Plpp3 leads to dopaminergic transmission deficits without neurodegeneration.
Volume: 6
Pages: 24028
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Publication
18037890 | J:130407
First Author: Ledgerwood LG
Year: 2008
Journal: Nat Immunol
Title: The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics.
Volume: 9
Issue: 1
Pages: 42-53
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Publication
12006579 | J:77809
First Author: Ishii I
Year: 2002
Journal: J Biol Chem
Title: Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3.
Volume: 277
Issue: 28
Pages: 25152-9
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Publication
30917312 | J:278292
First Author: Solinski HJ
Year: 2019
Journal: Cell Rep
Title: Nppb Neurons Are Sensors of Mast Cell-Induced Itch.
Volume: 26
Issue: 13
Pages: 3561-3573.e4
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Publication
28538737 | J:252520
First Author: Mendoza A
Year: 2017
Journal: Nature
Title: Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.
Volume: 546
Issue: 7656
Pages: 158-161
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Publication
26903652 | J:230998
First Author: Park K
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex.
Volume: 113
Issue: 10
Pages: E1334-42
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Publication
22695326 | J:198171
First Author: Park SW
Year: 2012
Journal: Kidney Int
Title: Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia.
Volume: 82
Issue: 8
Pages: 878-91
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Publication
15371328 | J:93030
First Author: Paik JH
Year: 2004
Journal: Genes Dev
Title: Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization.
Volume: 18
Issue: 19
Pages: 2392-403
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Publication
35781853 | J:347313
First Author: Skoug C
Year: 2022
Journal: Neurochem Res
Title: Sphingosine 1-Phoshpate Receptors are Located in Synapses and Control Spontaneous Activity of Mouse Neurons in Culture.
Volume: 47
Issue: 10
Pages: 3114-3125
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Publication
16319286 | J:107019
First Author: Skaznik-Wikiel ME
Year: 2006
Journal: Biol Reprod
Title: Sphingosine-1-phosphate receptor expression and signaling correlate with uterine prostaglandin-endoperoxide synthase 2 expression and angiogenesis during early pregnancy.
Volume: 74
Issue: 3
Pages: 569-76
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Publication
25111230 | J:216058
First Author: Bi Y
Year: 2014
Journal: Am J Pathol
Title: Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth.
Volume: 184
Issue: 10
Pages: 2791-802
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Publication
25348153 | J:219661
First Author: Wang X
Year: 2014
Journal: J Exp Med
Title: GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment.
Volume: 211
Issue: 12
Pages: 2351-9
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Publication
16314531 | J:103755
First Author: Mizugishi K
Year: 2005
Journal: Mol Cell Biol
Title: Essential role for sphingosine kinases in neural and vascular development.
Volume: 25
Issue: 24
Pages: 11113-21
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Publication
21668976 | J:173601
 
First Author: Poulsen RR
Year: 2011
Journal: BMC Dev Biol
Title: The Sphingosine-1-phospate receptor 1 mediates S1P action during cardiac development.
Volume: 11
Pages: 37
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Publication
22951644 | J:187683
First Author: Ben Shoham A
Year: 2012
Journal: Development
Title: S1P1 inhibits sprouting angiogenesis during vascular development.
Volume: 139
Issue: 20
Pages: 3859-69
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Publication
20407207 | J:161468
First Author: Olivera A
Year: 2010
Journal: J Clin Invest
Title: Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice.
Volume: 120
Issue: 5
Pages: 1429-40
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Publication
16980623 | J:112972
First Author: Kohno M
Year: 2006
Journal: Mol Cell Biol
Title: Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation.
Volume: 26
Issue: 19
Pages: 7211-23
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Publication
20852647 | J:166555
First Author: Liu G
Year: 2010
Journal: Nat Immunol
Title: The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.
Volume: 11
Issue: 11
Pages: 1047-56
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Publication
19483717 | J:150139
First Author: Liu G
Year: 2009
Journal: Nat Immunol
Title: The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.
Volume: 10
Issue: 7
Pages: 769-77
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Publication
27487469 | J:267305
   
First Author: Zhang Y
Year: 2016
Journal: Elife
Title: Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node.
Volume: 5
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Publication
32424104 | J:288614
First Author: Pirgova G
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Marginal zone SIGN-R1+ macrophages are essential for the maturation of germinal center B cells in the spleen.
Volume: 117
Issue: 22
Pages: 12295-12305
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Publication
15063179 | J:92203
First Author: Chae SS
Year: 2004
Journal: Dev Biol
Title: Regulation of limb development by the sphingosine 1-phosphate receptor S1p1/EDG-1 occurs via the hypoxia/VEGF axis.
Volume: 268
Issue: 2
Pages: 441-7
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Publication
11443127 | J:71372
First Author: Ishii I
Year: 2001
Journal: J Biol Chem
Title: Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3.
Volume: 276
Issue: 36
Pages: 33697-704
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Publication
30655318 | J:272408
First Author: Vaidya M
Year: 2019
Journal: J Lipid Res
Title: Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages.
Volume: 60
Issue: 3
Pages: 506-515
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Publication
20348395 | J:161551
First Author: Zhu D
Year: 2010
Journal: Blood
Title: Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor.
Volume: 115
Issue: 23
Pages: 4963-72
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Publication
22668972 | J:202209
First Author: Yang J
Year: 2012
Journal: Circulation
Title: Proximal cerebral arteries develop myogenic responsiveness in heart failure via tumor necrosis factor-α-dependent activation of sphingosine-1-phosphate signaling.
Volume: 126
Issue: 2
Pages: 196-206
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Publication
21256191 | J:175016
First Author: Catarzi S
Year: 2011
Journal: Biochim Biophys Acta
Title: Redox regulation of ERK1/2 activation induced by sphingosine 1-phosphate in fibroblasts: involvement of NADPH oxidase and platelet-derived growth factor receptor.
Volume: 1810
Issue: 4
Pages: 446-56
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Publication
19073640 | J:145748
First Author: Kirby RJ
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Dynamic regulation of sphingosine-1-phosphate homeostasis during development of mouse metanephric kidney.
Volume: 296
Issue: 3
Pages: F634-41
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Publication
18836449 | J:141431
First Author: Shiow LR
Year: 2008
Journal: Nat Immunol
Title: The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency.
Volume: 9
Issue: 11
Pages: 1307-15
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Publication
15689381 | J:97177
First Author: Edsbagge J
Year: 2005
Journal: Development
Title: Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme.
Volume: 132
Issue: 5
Pages: 1085-92
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Publication
22096531 | J:180974
First Author: Meng H
Year: 2011
Journal: PLoS One
Title: Loss of sphingosine kinase 1/S1P signaling impairs cell growth and survival of neurons and progenitor cells in the developing sensory ganglia.
Volume: 6
Issue: 11
Pages: e27150
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Publication
25377550 | J:217596
First Author: Nakajima C
Year: 2014
Journal: Development
Title: The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development.
Volume: 141
Issue: 23
Pages: 4513-25
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Publication
33053356 | J:301004
First Author: Di Marco B
Year: 2020
Journal: Cell Rep
Title: Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon.
Volume: 33
Issue: 2
Pages: 108256
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Publication
12401212 | J:79922
First Author: McGiffert C
Year: 2002
Journal: FEBS Lett
Title: Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis.
Volume: 531
Issue: 1
Pages: 103-8
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Publication
16434032 | J:107068
First Author: Wendler CC
Year: 2006
Journal: Dev Biol
Title: Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development.
Volume: 291
Issue: 2
Pages: 264-77
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Publication
32903671 | J:308908
 
First Author: Dai G
Year: 2020
Journal: Front Cell Dev Biol
Title: LncRNA H19 Regulates BMP2-Induced Hypertrophic Differentiation of Mesenchymal Stem Cells by Promoting Runx2 Phosphorylation.
Volume: 8
Pages: 580
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Publication
16513945 | J:108342
First Author: Terszowski G
Year: 2006
Journal: Science
Title: Evidence for a functional second thymus in mice.
Volume: 312
Issue: 5771
Pages: 284-7
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Publication
18924241 | J:140656
First Author: Ohuchi H
Year: 2008
Journal: Dev Dyn
Title: Expression patterns of the lysophospholipid receptor genes during mouse early development.
Volume: 237
Issue: 11
Pages: 3280-94
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Publication
20458606 | J:166492
First Author: Itoh R
Year: 2010
Journal: J Bone Miner Metab
Title: Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells.
Volume: 28
Issue: 6
Pages: 659-71
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Publication
11032855 | J:71961
First Author: Liu Y
Year: 2000
Journal: J Clin Invest
Title: Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation.
Volume: 106
Issue: 8
Pages: 951-61
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Publication
26276819 | J:230682
First Author: Lucitti JL
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: Chloride intracellular channel 4 is required for maturation of the cerebral collateral circulation.
Volume: 309
Issue: 7
Pages: H1141-50
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Publication
28535372 | J:241849
First Author: Ma S
Year: 2017
Journal: Dev Cell
Title: A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis.
Volume: 41
Issue: 4
Pages: 366-381.e4
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Publication
28709801 | J:259045
First Author: Onder L
Year: 2017
Journal: Immunity
Title: Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis.
Volume: 47
Issue: 1
Pages: 80-92.e4
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Publication
17141159 | J:127228
First Author: Lee JS
Year: 2006
Journal: Dev Cell
Title: Klf2 is an essential regulator of vascular hemodynamic forces in vivo.
Volume: 11
Issue: 6
Pages: 845-57
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Publication
21281624 | J:171472
First Author: Sand FW
Year: 2011
Journal: Dev Biol
Title: Growth-limiting role of endothelial cells in endoderm development.
Volume: 352
Issue: 2
Pages: 267-77
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Publication
15882861 | J:99326
First Author: Kuhnert F
Year: 2005
Journal: Dev Biol
Title: Dosage-dependent requirement for mouse Vezf1 in vascular system development.
Volume: 283
Issue: 1
Pages: 140-56
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Publication
21319224 | J:169062
First Author: López-Juárez A
Year: 2011
Journal: Glia
Title: Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development.
Volume: 59
Issue: 4
Pages: 577-89
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Publication
18804439 | J:140104
First Author: Franco CA
Year: 2008
Journal: Dev Cell
Title: Serum response factor is required for sprouting angiogenesis and vascular integrity.
Volume: 15
Issue: 3
Pages: 448-61
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Publication
15328020 | J:93141
First Author: Mattar P
Year: 2004
Journal: Dev Biol
Title: A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.
Volume: 273
Issue: 2
Pages: 373-89
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Publication
28924218 | J:251917
First Author: Wang Y
Year: 2017
Journal: Nat Commun
Title: Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.
Volume: 8
Issue: 1
Pages: 578
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
36598122 | J:334432
   
First Author: Zheng Z
Year: 2023
Journal: Elife
Title: Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 gene.
Volume: 12
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Publication
30451830 | J:268689
First Author: Hübner K
Year: 2018
Journal: Nat Commun
Title: Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling.
Volume: 9
Issue: 1
Pages: 4860
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Interaction Experiment
Lee H (2010)
Description: STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.
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Allele
S1pr1<em2Smoc> | MGI:7292153
Name: sphingosine-1-phosphate receptor 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6476210 | C57BL/6JSmoc-S1pr1<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Gt(ROSA)26Sor<tm1(CAG-S1pr1)Thla> | MGI:5903055
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1,Timothy Hla
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
S1pr1<em1Smoc> | MGI:7292152
Name: sphingosine-1-phosphate receptor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:5903062 | B6.C-Gt(ROSA)26Sor<tm1(CAG-S1pr1)Thla>/J
Attribute String: targeted mutation, mutant strain, congenic
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Allele
Gt(ROSA)26Sor<tm1(CAG-S1pr1*/tRFP,-S1pr1/EGFP)Srsb> | MGI:6149751
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Susan R Schwab
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence, No functional change, Reporter
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Publication
33658712 | J:306909
First Author: Baeyens A
Year: 2021
Journal: Nature
Title: Monocyte-derived S1P in the lymph node regulates immune responses.
Volume: 592
Issue: 7853
Pages: 290-295
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Allele
S1pr1<tm4.1Rlp> | MGI:6315193
Name: sphingosine-1-phosphate receptor 1; targeted mutation 4.1, Richard L Proia
Allele Type: Targeted
Attribute String: Reporter
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Strain
MGI:6476209 | C57BL/6JSmoc-S1pr1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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HT Experiment
GSE214014 | Kruppel-like factor 2 in VCAM1+ endothelial cells is a critical regulator of vascular inflammation
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE72184 | Next generation sequencing analysis of DN1 transcriptomes from Wild type, gl/gl and transgenic CD2-Ostm1 gl/gl mice
Series Id: E-GEOD-72184
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE70813 | Hobit and Blimp1 instruct a universal transcriptional program of tissue-residency in lymphocytes
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:6315198 | B6.Cg-S1pr1<tm4.1Rlp> Gt(ROSA)26Sor<tm2.1(luc*/Arrb2*)Rlp> Tyr<c-2J>/J
Attribute String: congenic, mutant strain, targeted mutation
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Publication
25176650 | J:243904
First Author: Huang C
Year: 2014
Journal: Cell Rep
Title: The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers.
Volume: 8
Issue: 5
Pages: 1497-508
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Publication
34260944 | J:319866
First Author: Okuniewska M
Year: 2021
Journal: Cell Rep
Title: SPNS2 enables T cell egress from lymph nodes during an immune response.
Volume: 36
Issue: 2
Pages: 109368
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Publication
38717905 | J:350663
First Author: Liu Q
Year: 2024
Journal: Cell Rep
Title: Circadian-clock-controlled endocrine and cytokine signals regulate multipotential innate lymphoid cell progenitors in the bone marrow.
Volume: 43
Issue: 5
Pages: 114200
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