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Search results 401 to 500 out of 3347 for Sacs

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Hits by Strain

Type Details Score
Allele
Pkhd1<tm1.1Ggg> | MGI:3759215
Name: polycystic kidney and hepatic disease 1; targeted mutation 1.1, Gregory G Germino
Allele Type: Targeted
Attribute String: Hypomorph
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Allele
Fat4<tm2Hmc> | MGI:3846574
Name: FAT atypical cadherin 4; targeted mutation 2, Helen McNeill
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tulp3<tm1c(EUCOMM)Hmgu> | MGI:5752546
Name: TUB like protein 3; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready
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MP Term
MP:0004792 | abnormal synaptic vesicle number
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MP Term
MP:0001183 | overexpanded pulmonary alveolus
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Genotype
Genotype
Symbol: Agtr1a/Agtr1a Agtr1b/Agtr1b Hprt1/?
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
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MP Term
MP:0010908 | dilated pulmonary alveolar duct
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Genotype
Genotype
Symbol: Nphp3/Nphp3
Background: involves: KK
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cys1/Cys1
Background: involves: C57BL/6J * CD-1
Zygosity: hm
Has Mutant Allele: true
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MP Term
MP:0004769 | abnormal synaptic vesicle morphology
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Genotype
Genotype
Symbol: Mmp9/Mmp9 Sftpd/Sftpd
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mmp12/Mmp12 Sftpd/Sftpd
Background: involves: 129P2/OlaHsd * 129X1/SvJ * Black Swiss * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wnt9b/Wnt9b Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prkcsh/Prkcsh Tg(CAG-cre/Esr1*)1Lbe/?
Background: involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sec63/Sec63 Tg(CAG-cre/Esr1*)1Lbe/?
Background: involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd2/Pkd2<+> Sec63/Sec63 Tg(Cdh16-cre)91Igr/?
Background: involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hnf1b/Hnf1b<+> Wnt4/Wnt4<+>
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Spata22/Spata22
Background: C3.B6-Spata22
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hoxa5/Hoxa5<+> Tg(Sftpc-cre)1Blh/?
Background: involves: 129 * C57BL/6J * DBA/2 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hoxa5/Hoxa5 Tg(Sftpc-cre)1Blh/?
Background: involves: 129 * C57BL/6J * DBA/2 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pald1/Pald1<+>
Background: B6.Cg-Pald1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hoxb3os/Hoxb3os Pkd1/Pkd1 Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hoxb3os/Hoxb3os Pkd1/Pkd1
Background: involves: 129 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Allele
Pkd1<tm1Maa> | MGI:2183523
Name: polycystin 1, transient receptor potential channel interacting; targeted mutation 1, M Armin Arnout
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Pkhd1<tm2Cjwa> | MGI:5438324
Name: polycystic kidney and hepatic disease 1; targeted mutation 2, Christopher J Ward
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout
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Allele
Prkcsh<tm1Som> | MGI:5442170
Name: protein kinase C substrate 80K-H; targeted mutation 1, Stefan Somlo
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Sec63<tm1Som> | MGI:5442171
Name: SEC63 homolog, protein translocation regulator; targeted mutation 1, Stefan Somlo
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Pkd1/Pkd1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxp2/Foxp2
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
9139715 | J:40321
First Author: Takahashi S
Year: 1997
Journal: J Biol Chem
Title: Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene.
Volume: 272
Issue: 19
Pages: 12611-5
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Gene
1080 | CFTR
Type: gene
Organism: human
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HT Experiment
GSE139587 | SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms (scRNA-seq: batch2)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE131196 | SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein Coding Gene
MGI:3036255 | Tmtc3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30158284 | J:267708
 
First Author: Tunster SJ
Year: 2018
Journal: Dis Model Mech
Title: Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome.
Volume: 11
Issue: 11
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HT Experiment
E-GEOD-32116 | ARID-DNA interactions are essential for SWI/SNF function
Series Id: GSE32116
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE111080 | RNA-seq analysis of Slc39a8 (neo/neo) versus wild-type mice: yolk sac, placenta and fetal liver, kidney, lung, heart and cerebellum
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE204896 | A trio of bipotent precursors seeds the mesenchymal, haematopoietic, and endothelial lineages of the yolk sac
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE103789 | A novel role for Lyl1 in primitive erythropoiesis
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE271281 | An essential role for Cmtr2 in mammalian embryonic development [RNA-Seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Pkd1<tm1Djmp> | MGI:3521583
Name: polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Dorien JM Peters
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph
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Allele
Pkhd1<tm1Som> | MGI:3774015
Name: polycystic kidney and hepatic disease 1; targeted mutation 1, Stefan Somlo
Allele Type: Targeted
Attribute String: Hypomorph
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Allele
Tg(Pkd1)18Mtru | MGI:4437719
Name: transgene insertion 18, Marie Trudel
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Pkhd1<tm1Sswi> | MGI:5430994
Name: polycystic kidney and hepatic disease 1; targeted mutation 1, Scott S Williams
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Dzip1l<warpy> | MGI:5563494
 
Name: DAZ interacting protein 1-like; warpy
Allele Type: Chemically induced (ENU)
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Allele
Pkd2<tm1.1Gwu> | MGI:6201745
Name: polycystin 2, transient receptor potential cation channel; targeted mutation 1.1, Guanqing Wu
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Pde1a<em1Cjwa> | MGI:6343412
Name: phosphodiesterase 1A, calmodulin-dependent; endonuclease-mediated mutation 1, Christopher Ward
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Pde1a<em2Cjwa> | MGI:6343413
Name: phosphodiesterase 1A, calmodulin-dependent; endonuclease-mediated mutation 2, Christopher Ward
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Nek8/Nek8
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd1/Pkd1<+> Pkhd1/Pkhd1
Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ucp2/Ucp2
Background: B6.129S4-Ucp2
Zygosity: hm
Has Mutant Allele: true
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Allele
Hes5<tm1Fgu> | MGI:2149674
Name: hes family bHLH transcription factor 5; targeted mutation 1, Francois Guillemot
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
T(2;10)67Gso | MGI:2154472
 
Name: reciprocal translocation, Chr 2 and 10, Generoso 67
Allele Type: Chemically induced (other)
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Allele
Oc90<tm1Ywl> | MGI:3715290
Name: otoconin 90; targeted mutation 1, Yunxia Wang Lundberg
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cav1<tm1.1Aia> | MGI:5141474
Name: caveolin 1, caveolae protein; targeted mutation 1.1, Alexander I Agoulnik
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Slc12a2<tm1.1Jheb> | MGI:5538339
Name: solute carrier family 12, member 2; targeted mutation 1.1, Jean M Hebert
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tg(tetO-Aimp1)29872Mcla | MGI:5587972
Name: transgene insertion 29872, Matthias Clauss
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Allele
Pkhd1<cyli> | MGI:7568836
Name: polycystic kidney and hepatic disease 1; cystic liver
Allele Type: Spontaneous
Attribute String: Modified isoform(s)
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Allele
Cachd1<tow> | MGI:6827187
Name: cache domain containing 1; tilt-o-whirl
Allele Type: Spontaneous
Attribute String: Not Specified
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Genotype
Genotype
Symbol: Pkd1/Pkd1
Background: involves: 129S4/SvJae * Black Swiss * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Otx1/Otx1
Background: C57BL/6J-Otx1/GrsrJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2/Pax2
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Unc13a/Unc13a<+> Unc13b/Unc13b
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd1/Pkd1 Tg(Cdh16-cre/ERT2)F427Djmp/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf7/Fgf7
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd2/Pkd2 Meox2/Meox2<+>
Background: involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cav1/Cav1 crsp/crsp
Background: involves: 129S7/SvEvBrd * C57BL/6J * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkhd1/Pkhd1
Background: either: B6.129(Cg)-Pkhd1 or C.129(Cg)-Pkhd1
Zygosity: hm
Has Mutant Allele: true
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Publication
27864380 | J:237500
First Author: Osipovich AB
Year: 2016
Journal: Development
Title: Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.
Volume: 143
Issue: 24
Pages: 4595-4607
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Publication
27522498 | J:239252
First Author: Zhang T
Year: 2016
Journal: Hum Mol Genet
Title: Haploinsufficiency of Klippel-Trenaunay syndrome gene Aggf1 inhibits developmental and pathological angiogenesis by inactivating PI3K and AKT and disrupts vascular integrity by activating VE-cadherin.
Volume: 25
Issue: 23
Pages: 5094-5110
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GO Term
GO:0030324 | lung development
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GO Term
GO:0060437 | lung growth
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Publication
15721306 | J:96209
First Author: Miyata K
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the alpha/beta hydrolase domain containing 2 gene.
Volume: 329
Issue: 1
Pages: 296-304
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Publication
21438071 | J:171626
First Author: Li S
Year: 2011
Journal: Dev Dyn
Title: Foxn4 influences alveologenesis during lung development.
Volume: 240
Issue: 6
Pages: 1512-7
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Publication
17826737 | J:125199
First Author: Wei P
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Defective vascular morphogenesis and mid-gestation embryonic death in mice lacking RA-GEF-1.
Volume: 363
Issue: 1
Pages: 106-12
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Publication
24157948 | J:217259
First Author: Peyronnet R
Year: 2013
Journal: EMBO Rep
Title: Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells.
Volume: 14
Issue: 12
Pages: 1143-8
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Publication
9200616 | J:41435
First Author: Shalaby F
Year: 1997
Journal: Cell
Title: A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis.
Volume: 89
Issue: 6
Pages: 981-90
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Publication
10079220 | J:53289
First Author: Yang X
Year: 1999
Journal: Development
Title: Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5.
Volume: 126
Issue: 8
Pages: 1571-80
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Publication
28781167 | J:256121
First Author: Koren D
Year: 2017
Journal: Neuron
Title: Cross-compartmental Modulation of Dendritic Signals for Retinal Direction Selectivity.
Volume: 95
Issue: 4
Pages: 914-927.e4
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Publication
29420258 | J:260760
First Author: Nabhan AN
Year: 2018
Journal: Science
Title: Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells.
Volume: 359
Issue: 6380
Pages: 1118-1123
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Publication
19097117 | J:142646
First Author: Yi L
Year: 2009
Journal: Dev Dyn
Title: Fibroblast growth factor 9 signaling inhibits airway smooth muscle differentiation in mouse lung.
Volume: 238
Issue: 1
Pages: 123-37
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Publication
27713415 | J:242610
 
First Author: Baik J
Year: 2016
Journal: Nat Commun
Title: Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2.
Volume: 7
Pages: 13101
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Publication
9250681 | J:42409
First Author: Wang LC
Year: 1997
Journal: EMBO J
Title: Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL.
Volume: 16
Issue: 14
Pages: 4374-83
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Publication
28994389 | J:249431
   
First Author: Honda K
Year: 2017
Journal: Elife
Title: Molecular architecture underlying fluid absorption by the developing inner ear.
Volume: 6
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Publication
25155960 | J:221541
First Author: Vlasits AL
Year: 2014
Journal: Neuron
Title: Visual stimulation switches the polarity of excitatory input to starburst amacrine cells.
Volume: 83
Issue: 5
Pages: 1172-84
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Publication
26140686 | J:225999
   
First Author: Kostadinov D
Year: 2015
Journal: Elife
Title: Protocadherin-dependent dendritic self-avoidance regulates neural connectivity and circuit function.
Volume: 4
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Publication
27238865 | J:270885
First Author: Sethuramanujam S
Year: 2016
Journal: Neuron
Title: A Central Role for Mixed Acetylcholine/GABA Transmission in Direction Coding in the Retina.
Volume: 90
Issue: 6
Pages: 1243-1256
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Publication
23283320 | J:255058
First Author: Beier KT
Year: 2013
Journal: J Neurosci
Title: Transsynaptic tracing with vesicular stomatitis virus reveals novel retinal circuitry.
Volume: 33
Issue: 1
Pages: 35-51
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Publication
31812516 | J:290493
First Author: Peng YR
Year: 2020
Journal: Neuron
Title: Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch.
Volume: 105
Issue: 3
Pages: 464-474.e6
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Publication
34910920 | J:321540
First Author: Hellmer CB
Year: 2021
Journal: Cell Rep
Title: Cholinergic feedback to bipolar cells contributes to motion detection in the mouse retina.
Volume: 37
Issue: 11
Pages: 110106
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Publication
35196487 | J:321720
First Author: Jain V
Year: 2022
Journal: Cell Rep
Title: Gain control by sparse, ultra-slow glycinergic synapses.
Volume: 38
Issue: 8
Pages: 110410
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Publication
38418467 | J:349218
First Author: Acarón Ledesma H
Year: 2024
Journal: Nat Commun
Title: Dendritic mGluR2 and perisomatic Kv3 signaling regulate dendritic computation of mouse starburst amacrine cells.
Volume: 15
Issue: 1
Pages: 1819
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Publication
27929372 | J:239453
   
First Author: Chen Q
Year: 2016
Journal: Elife
Title: Stimulus-dependent recruitment of lateral inhibition underlies retinal direction selectivity.
Volume: 5
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Publication
33269700 | J:308414
   
First Author: Chen Q
Year: 2020
Journal: Elife
Title: Preserving inhibition with a disinhibitory microcircuit in the retina.
Volume: 9
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Publication
31160566 | J:277899
First Author: Huang X
Year: 2019
Journal: Nat Commun
Title: Neural mechanisms of contextual modulation in the retinal direction selective circuit.
Volume: 10
Issue: 1
Pages: 2431
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Publication
33686659 | J:308526
First Author: Xu Z
Year: 2021
Journal: FEBS Lett
Title: Centrosomal protein FOR20 knockout mice display embryonic lethality and left-right patterning defects.
Volume: 595
Issue: 10
Pages: 1462-1472
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Publication
29467473 | J:272362
First Author: Su X
Year: 2018
Journal: Cell Death Dis
Title: Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development.
Volume: 9
Issue: 3
Pages: 302
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Allele
wal | MGI:1856644
 
Name: waved alopecia
Allele Type: Spontaneous
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Heritable Phenotypic Marker
MGI:98942 | wal
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Allele
Slc30a3<tm1Rpa> | MGI:1859820
Name: solute carrier family 30 (zinc transporter), member 3; targeted mutation 1, Richard D Palmiter
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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