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Search results 401 to 500 out of 31756 for Set

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
705771 | SETSIP
Type: gene
Organism: macaque, rhesus
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Gene
706782 | SBF2
Type: gene
Organism: macaque, rhesus
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Gene
708019 | SETD9
Type: gene
Organism: macaque, rhesus
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Gene
713861 | LOC713861
Type: gene
Organism: macaque, rhesus
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Gene
715955 | SBF1
Type: gene
Organism: macaque, rhesus
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Gene
717067 | LOC717067
Type: gene
Organism: macaque, rhesus
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Gene
101750922 | SETD6
Type: gene
Organism: chicken
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Gene
100490309 | setdb1
Type: gene
Organism: frog, western clawed
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Gene
100492810 | setd2
Type: gene
Organism: frog, western clawed
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Gene
549859 | setd4
Type: gene
Organism: frog, western clawed
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Gene
780106 | setd1b
Type: gene
Organism: frog, western clawed
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Gene
100036675 | sbf2
Type: gene
Organism: frog, western clawed
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Gene
100124743 | setdb2
Type: gene
Organism: frog, western clawed
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Gene
100125067 | setbp1
Type: gene
Organism: frog, western clawed
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Gene
100125154 | sbf1
Type: gene
Organism: frog, western clawed
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Gene
100125156 | setd6
Type: gene
Organism: frog, western clawed
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Gene
100145036 | setd5
Type: gene
Organism: frog, western clawed
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Gene
100379905 | setd9
Type: gene
Organism: frog, western clawed
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Gene
100487270 | setd1a
Type: gene
Organism: frog, western clawed
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Gene
106995266 | LOC106995266
Type: gene
Organism: macaque, rhesus
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Gene
106999470 | LOC106999470
Type: gene
Organism: macaque, rhesus
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Gene
106995956 | LOC106995956
Type: gene
Organism: macaque, rhesus
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Gene
106993412 | LOC106993412
Type: gene
Organism: macaque, rhesus
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Gene
106998747 | LOC106998747
Type: gene
Organism: macaque, rhesus
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Publication
28250819 | J:306882
 
First Author: Kidder BL
Year: 2017
Journal: Epigenetics Chromatin
Title: SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation.
Volume: 10
Pages: 8
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Publication
35151207 | J:321816
 
First Author: Kano S
Year: 2022
Journal: Biochem Biophys Res Commun
Title: The role of the histone methyltransferase SET domain bifurcated 1 during palatal development.
Volume: 598
Pages: 74-80
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Publication
9632640 | -
First Author: Huang S
Year: 1998
Journal: J Biol Chem
Title: The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression.
Volume: 273
Issue: 26
Pages: 15933-9
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Protein Domain
IPR001214 | SET_dom
Type: Domain
Description: The SET domain is a 130 to 140 amino acid, evolutionary well conservedsequence motif that was initially characterised in the Drosophila proteins Su(var)3-9, Enhancer-of-zeste and Trithorax. In addition to these chromosomal proteins modulating gene activities and/or chromatin structure, the SET domain is found in proteins of diverse functions ranging from yeast to mammals, but also including some bacteria and viruses [, ].The SET domains of mammalian SUV39H1 and 2 and fission yeast clr4 have been shown to be necessary for the methylation of lysine-9 in the histone H3 N terminus []. However, this histone methyltransferase (HMTase) activity is probably restricted to a subset of SET domain proteins as it requires the combination of the SET domain with the adjacent cysteine-rich regions, one located N-terminally (pre-SET) and the other posterior to the SET domain (post-SET). Post- and pre- SET regions seem then to play a crucial role when it comes to substrate recognition and enzymatic activity [, ].The structure of the SET domain and the two adjacent regions pre-SET and post-SET have been solved [, , ]. The SET structure is all beta, but consists only in sets of few short strands composing no more than a couple of small sheets. Consequently the SET structure is mostly defined by turns and loops. An unusual feature is that the SET core is made up of two discontinual segments of the primary sequence forming an approximate L shape [, , ]. Two of the most conserved motifs in the SET domain are constituted by (1) a stretch at the C-terminal containing a strictly conserved tyrosine residue and (2) a preceding loop inside which the C-terminal segment passes forming a knot-like structure, but not quite a true knot. These two regions have been proven to be essential for SAM binding and catalysis, particularly the invariant tyrosine where in all likelihood catalysis takes place [, ].
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Publication
28753426 | J:250389
First Author: Chen K
Year: 2017
Journal: Cell
Title: Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity.
Volume: 170
Issue: 3
Pages: 492-506.e14
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Publication
30038239 | J:265894
First Author: Dewan A
Year: 2018
Journal: Nat Commun
Title: Single olfactory receptors set odor detection thresholds.
Volume: 9
Issue: 1
Pages: 2887
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Publication
16682010 | J:108985
First Author: Kim SM
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity.
Volume: 345
Issue: 1
Pages: 318-23
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UniProt Feature
UniProt Feature
Begin: 1
Description: SET and MYND domain-containing protein 4
Type: chain
End: 799
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Publication
12389038 | -
First Author: Jacobs SA
Year: 2002
Journal: Nat Struct Biol
Title: The active site of the SET domain is constructed on a knot.
Volume: 9
Issue: 11
Pages: 833-8
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Publication
17005568 | -
First Author: Porras-Yakushi TR
Year: 2006
Journal: J Biol Chem
Title: A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10.
Volume: 281
Issue: 47
Pages: 35835-45
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HT Sample
GSM28499 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28500 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28501 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28502 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28503 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28504 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28505 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28506 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28507 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28508 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28509 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28510 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28511 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28512 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28513 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28514 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28515 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28516 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28517 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28518 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28519 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28520 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28521 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28522 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28523 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28524 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28525 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28526 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28527 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28528 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28529 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28530 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28531 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28532 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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HT Sample
GSM28533 2
       
Organism Name: mouse, laboratory
Notes: Reference oligonucleotide set
Curation Status: Not curated (No data stored)
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Protein
Q8R5A0
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: false
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HT Experiment
GSE100106 | 10X Genomics scRNA sequence Lacrimal Data set
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Protein
A0A3B2WBF6
Organism: Mus musculus/domesticus
Length: 48  
Fragment?: true
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Publication
12372305 | -
First Author: Zhang X
Year: 2002
Journal: Cell
Title: Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase.
Volume: 111
Issue: 1
Pages: 117-27
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Protein
Q2YDW7
Organism: Mus musculus/domesticus
Length: 349  
Fragment?: false
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Protein Coding Gene
MGI:1920145 | Setd5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26320581 | J:247433
First Author: Zhang Y
Year: 2015
Journal: Structure
Title: Evolving Catalytic Properties of the MLL Family SET Domain.
Volume: 23
Issue: 10
Pages: 1921-33
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Pseudogene
MGP_CAROLIEiJ_G0037007 | -
Type: pseudogene
Organism: Mus caroli
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Pseudogene
MGP_129S1SvImJ_G0039862 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_AJ_G0039868 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_AKRJ_G0039792 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_BALBcJ_G0039845 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_C3HHeJ_G0039491 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGI_C57BL6J_3705835 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_C57BL6NJ_G0040411 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_CASTEiJ_G0038597 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_CBAJ_G0039460 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_DBA2J_G0039663 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_FVBNJ_G0039621 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_LPJ_G0039701 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_NODShiLtJ_G0039618 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_PWKPhJ_G0038270 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_WSBEiJ_G0038828 | -
Type: pseudogene
Organism: mouse, laboratory
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Pseudogene
MGP_PahariEiJ_G0035131 | -
Type: pseudogene
Organism: Mus pahari
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Pseudogene
MGP_SPRETEiJ_G0038014 | -
Type: pseudogene
Organism: Mus spretus
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Publication
26780092 | J:356775
First Author: Fan J
Year: 2016
Journal: Nat Methods
Title: Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis.
Volume: 13
Issue: 3
Pages: 241-4
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Publication
27812132 | -
First Author: Mas-Y-Mas S
Year: 2016
Journal: PLoS One
Title: The Human Mixed Lineage Leukemia 5 (MLL5), a Sequentially and Structurally Divergent SET Domain-Containing Protein with No Intrinsic Catalytic Activity.
Volume: 11
Issue: 11
Pages: e0165139
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Publication
9618163 | J:48436
First Author: Stec I
Year: 1998
Journal: Hum Mol Genet
Title: WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma.
Volume: 7
Issue: 7
Pages: 1071-82
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Gene
288330 | Set-ps11
Type: gene
Organism: rat
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Gene
365967 | Set-ps12
Type: gene
Organism: rat
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Gene
367277 | Set-ps13
Type: gene
Organism: rat
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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