|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 401 to 500 out of 556 for Socs3

<< First    < Previous  |  Next >    Last >>
0.033s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
31214662 | J:277889
First Author: Cordonier EL
Year: 2019
Journal: J Endocr Soc
Title: Luciferase Reporter Mice for In Vivo Monitoring and Ex Vivo Assessment of Hypothalamic Signaling of Socs3 Expression.
Volume: 3
Issue: 7
Pages: 1246-1260
•
•
•
•
•
Transgene
MGI:3783702 | Tg(Lck-Socs3)1Kubo
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Publication
25617409 | J:244379
First Author: Pasricha S
Year: 2015
Journal: G3 (Bethesda)
Title: Identification of eQTLs for hepatic Xbp1s and Socs3 gene expression in mice fed a high-fat, high-caloric diet.
Volume: 5
Issue: 4
Pages: 487-96
•
•
•
•
•
Publication
21617181 | J:186748
First Author: Serrano-Marco L
Year: 2011
Journal: Diabetes
Title: Activation of peroxisome proliferator-activated receptor-β/-δ (PPAR-β/-δ) ameliorates insulin signaling and reduces SOCS3 levels by inhibiting STAT3 in interleukin-6-stimulated adipocytes.
Volume: 60
Issue: 7
Pages: 1990-9
•
•
•
•
•
Publication
27286706 | J:236102
First Author: Sun D
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Matrine suppresses airway inflammation by downregulating SOCS3 expression via inhibition of NF-κB signaling in airway epithelial cells and asthmatic mice.
Volume: 477
Issue: 1
Pages: 83-90
•
•
•
•
•
Interaction Experiment
Orabona C (2008)
Description: SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis.
•
•
•
•
•
Interaction Experiment
Kershaw NJ (2013)
Description: SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5707739
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5707760
Age: embryonic day 12.5
Note: Expression was detected on erythroid lineage committed cells. Co-expression with Socs3 was noted.
Specimen Label: 1I
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5707739
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5707760
Age: embryonic day 12.5
Note: Expression was detected on erythroid lineage committed cells. Co-expression with Socs3 was noted.
Specimen Label: 1K
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5707739
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5707760
Age: embryonic day 12.5
Note: Expression was detected on erythroid lineage committed cells. Co-expression with Socs3 was noted.
Specimen Label: 1L
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5707739
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5707760
Age: embryonic day 12.5
Note: Expression was detected on erythroid lineage committed cells. Co-expression with Socs3 was noted.
Specimen Label: 1M
Detected: true
Specimen Num: 8
•
•
•
•
•
Allele
Socs3<em1Smoc> | MGI:7292518
Name: suppressor of cytokine signaling 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Strain
MGI:6355216 | C57BL/6JSmoc-Socs3<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Publication
11018044 | -
First Author: Bjorbak C
Year: 2000
Journal: J Biol Chem
Title: SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985.
Volume: 275
Issue: 51
Pages: 40649-57
•
•
•
•
•
Publication
15554904 | -
First Author: Ehlting C
Year: 2005
Journal: Biochem J
Title: Sp3 is involved in the regulation of SOCS3 gene expression.
Volume: 387
Issue: Pt 3
Pages: 737-45
•
•
•
•
•
Allele
Tg(Socs3-luc2)6123Mfuk | MGI:6355994
Name: transgene insertion 6123, Makoto Fukada
Allele Type: Transgenic
Attribute String: Reporter
•
•
•
•
•
HT Experiment
GSE80784 | Transcriptomics Analysis Of SOCS3-deficient keratinocytes: Revealed Insights Into Progression of Chronic Skin Disease
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
Publication
11108838 | -
First Author: Eyckerman S
Year: 2000
Journal: FEBS Lett
Title: Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor.
Volume: 486
Issue: 1
Pages: 33-7
•
•
•
•
•
Publication
19088199 | -
First Author: Orabona C
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis.
Volume: 105
Issue: 52
Pages: 20828-33
•
•
•
•
•
Publication
12403768 | -
First Author: Lehmann U
Year: 2003
Journal: J Biol Chem
Title: SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130.
Volume: 278
Issue: 1
Pages: 661-71
•
•
•
•
•
Publication
19027008 | -
First Author: Zou T
Year: 2008
Journal: FEBS Lett
Title: The role of microtubule-associated protein 1S in SOCS3 regulation of IL-6 signaling.
Volume: 582
Issue: 29
Pages: 4015-22
•
•
•
•
•
Strain
MGI:6355995 | C57BL/6-Tg(Socs3-luc2)6123Mfuk/J
Attribute String: transgenic, mutant strain, coisogenic
•
•
•
•
•
Publication
16630890 | -
First Author: Babon JJ
Year: 2006
Journal: Mol Cell
Title: The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.
Volume: 22
Issue: 2
Pages: 205-16
•
•
•
•
•
Publication
22084247 | -
First Author: Zhang WN
Year: 2012
Journal: J Biol Chem
Title: CUEDC2 (CUE domain-containing 2) and SOCS3 (suppressors of cytokine signaling 3) cooperate to negatively regulate Janus kinase 1/signal transducers and activators of transcription 3 signaling.
Volume: 287
Issue: 1
Pages: 382-92
•
•
•
•
•
Protein Domain
IPR035863 | SOCS3_SH2
Type: Domain
Description: This entry represents the SH2 domain of SOCS3.Cytokine signaling mediated by the JAK-STAT pathway plays essential roles in differentiation, maturation, proliferation and apoptosis of a various types of cells. Suppressor of cytokine signaling (SOCS) proteins are negative feedback regulators of the JAK-STAT signaling pathway. SOCS1 and SOCS3 are potent inhibitors of JAKs and can play pivotal roles in inflammation, as well as in the development and progression of cancers []. All SOCS share a central SH2 domain and a C-terminal SOCS box, but only SOCS1 and SOCS3 possess a kinase inhibitory region immediately upstream of the central SH2 [].SOCS3 interacts with gp130, a common cytokine receptor for interleukin (IL)-6, leukemia inhibitory factor (LIF) and other members of the IL-6 family of cytokines. SOCS3 has been reported also to interact with the leptin receptor, erythropoietin receptor, insulin receptor, IL-12beta receptor and granulocyte-colony stimulating factor receptor [].
•
•
•
•
•
Protein Domain
IPR028411 | SOCS1
Type: Family
Description: Cytokine signaling mediated by the JAK-STAT pathway plays essential roles in differentiation, maturation, proliferation and apoptosis of a various types of cells. Suppressor of cytokine signaling (SOCS) proteins are negative feedback regulators of the JAK-STAT signaling pathway. SOCS1 and SOCS3 are potent inhibitors of JAKs and can play pivotal roles in inflammation, as well as in the development and progression of cancers []. All SOCS share a central SH2 domain and a C-terminal SOCS box, but only SOCS1 and SOCS3 possess a kinase inhibitory region immediately upstream of the central SH2 [].SOCS1 plays a key role in the negative regulation of interferon-gamma signaling and in T cell differentiation [, , ].
•
•
•
•
•
Publication
9727029 | -
First Author: Dey BR
Year: 1998
Journal: J Biol Chem
Title: Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor.
Volume: 273
Issue: 37
Pages: 24095-101
•
•
•
•
•
Publication
12552091 | -
First Author: Leung KC
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2.
Volume: 100
Issue: 3
Pages: 1016-21
•
•
•
•
•
Publication
21893603 | -
First Author: Takahashi R
Year: 2011
Journal: J Exp Med
Title: SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production.
Volume: 208
Issue: 10
Pages: 2055-67
•
•
•
•
•
Protein
D3Z441
Organism: Mus musculus/domesticus
Length: 62  
Fragment?: true
•
•
•
•
•
Publication
12645661 | -
First Author: Larsen L
Year: 2002
Journal: APMIS
Title: Suppressors of cytokine signalling: SOCS.
Volume: 110
Issue: 12
Pages: 833-44
•
•
•
•
•
Protein Domain
IPR028410 | SOCS2
Type: Family
Description: Cytokine signaling mediated by the JAK-STAT pathway plays essential roles in differentiation, maturation, proliferation and apoptosis of a various types of cells. Suppressor of cytokine signaling (SOCS) proteins are negative feedback regulators of the JAK-STAT signaling pathway. SOCS1 and SOCS3 are potent inhibitors of JAKs and can play pivotal roles in inflammation, as well as in the development and progression of cancers []. All SOCS share a central SH2 domain and a C-terminal SOCS box, but only SOCS1 and SOCS3 possess a kinase inhibitory region immediately upstream of the central SH2 [].SOCS2 is necessary for normal growth regulation []. It appears to be a negative regulator in the growth hormone/IGF1 signaling pathway [, ].
•
•
•
•
•
Protein Domain
IPR035861 | SOCS1_SH2
Type: Domain
Description: This entry represents the SH2 domain of SOCS1.Cytokine signaling mediated by the JAK-STAT pathway plays essential roles in differentiation, maturation, proliferation and apoptosis of a various types of cells. Suppressor of cytokine signaling (SOCS) proteins are negative feedback regulators of the JAK-STAT signaling pathway. SOCS1 and SOCS3 are potent inhibitors of JAKs and can play pivotal roles in inflammation, as well as in the development and progression of cancers []. All SOCS share a central SH2 domain and a C-terminal SOCS box, but only SOCS1 and SOCS3 possess a kinase inhibitory region immediately upstream of the central SH2 [].SOCS1 plays a key role in the negative regulation of interferon-gamma signaling and in T cell differentiation [, , ].
•
•
•
•
•
Protein Domain
IPR035862 | SOCS2_SH2
Type: Domain
Description: This entry represents the SH2 domain of SOCS2.Cytokine signaling mediated by the JAK-STAT pathway plays essential roles in differentiation, maturation, proliferation and apoptosis of a various types of cells. Suppressor of cytokine signaling (SOCS) proteins are negative feedback regulators of the JAK-STAT signaling pathway. SOCS1 and SOCS3 are potent inhibitors of JAKs and can play pivotal roles in inflammation, as well as in the development and progression of cancers []. All SOCS share a central SH2 domain and a C-terminal SOCS box, but only SOCS1 and SOCS3 possess a kinase inhibitory region immediately upstream of the central SH2 [].SOCS2 is necessary for normal growth regulation []. It appears to be a negative regulator in the growth hormone/IGF1 signaling pathway [, ].
•
•
•
•
•
Publication
11553846 | -
First Author: Krebs DL
Year: 2001
Journal: Stem Cells
Title: SOCS proteins: negative regulators of cytokine signaling.
Volume: 19
Issue: 5
Pages: 378-87
•
•
•
•
•
Protein
D3Z355
Organism: Mus musculus/domesticus
Length: 70  
Fragment?: true
•
•
•
•
•
Publication
18077004 | J:130590
First Author: Osborne-Hereford AV
Year: 2008
Journal: J Neuroimmunol
Title: Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.
Volume: 193
Issue: 1-2
Pages: 130-9
•
•
•
•
•
Protein
O35717
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
•
•
•
•
•
Protein
O35716
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
•
•
•
•
•
Protein
F6RVG2
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: true
•
•
•
•
•
Protein
Q548Q7
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
•
•
•
•
•
Publication
22118527 | J:178927
First Author: Cui W
Year: 2011
Journal: Immunity
Title: An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells.
Volume: 35
Issue: 5
Pages: 792-805
•
•
•
•
•
Publication
26260587 | J:224996
 
First Author: Nakamura R
Year: 2015
Journal: Nat Commun
Title: IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis.
Volume: 6
Pages: 7847
•
•
•
•
•
Publication
26366710 | J:228914
First Author: Ortega-Molina A
Year: 2015
Journal: Nat Med
Title: The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.
Volume: 21
Issue: 10
Pages: 1199-208
•
•
•
•
•
Publication
37653141 | J:342226
First Author: Goswami S
Year: 2023
Journal: Nat Cancer
Title: Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade.
Volume: 4
Issue: 10
Pages: 1455-1473
•
•
•
•
•
Publication
32209473 | J:288258
First Author: Jin J
Year: 2020
Journal: Cell Rep
Title: CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b-CD103+ DCs.
Volume: 30
Issue: 12
Pages: 4124-4136.e5
•
•
•
•
•
Publication
20065110 | J:159490
First Author: Li LX
Year: 2010
Journal: J Immunol
Title: A Flt3- and Ras-dependent pathway primes B cell development by inducing a state of IL-7 responsiveness.
Volume: 184
Issue: 4
Pages: 1728-36
•
•
•
•
•
Publication
26602020 | J:259839
First Author: Na YR
Year: 2015
Journal: Sci Signal
Title: The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production.
Volume: 8
Issue: 404
Pages: ra121
•
•
•
•
•
Publication
36057627 | J:328842
First Author: Xiong X
Year: 2022
Journal: Nat Commun
Title: Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity.
Volume: 13
Issue: 1
Pages: 5192
•
•
•
•
•
Publication
28710273 | J:243981
First Author: Zhang Y
Year: 2017
Journal: J Exp Med
Title: PD-L1 up-regulation restrains Th17 cell differentiation in STAT3 loss- and STAT1 gain-of-function patients.
Volume: 214
Issue: 9
Pages: 2523-2533
•
•
•
•
•
Publication
25109392 | J:301701
 
First Author: Übel C
Year: 2014
Journal: Sci Rep
Title: Role of Tyk-2 in Th9 and Th17 cells in allergic asthma.
Volume: 4
Pages: 5865
•
•
•
•
•
Publication
19508864 | J:150654
First Author: Cho HJ
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Constitutive JAK2/STAT1 activation regulates endogenous BACE1 expression in neurons.
Volume: 386
Issue: 1
Pages: 175-80
•
•
•
•
•
Publication
19766538 | J:155235
First Author: Fushimi S
Year: 2009
Journal: Clin Immunol
Title: Forced expression of suppressor of cytokine signaling 3 in T cells protects the development of concanavalin A-induced hepatitis in mice.
Volume: 133
Issue: 3
Pages: 437-46
•
•
•
•
•
Publication
30093408 | J:272818
First Author: Whitley SK
Year: 2018
Journal: J Biol Chem
Title: IL-1R signaling promotes STAT3 and NF-κB factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription.
Volume: 293
Issue: 41
Pages: 15790-15800
•
•
•
•
•
Publication
37578862 | J:340114
First Author: Xie J
Year: 2023
Journal: Cell Rep
Title: The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation.
Volume: 42
Issue: 8
Pages: 112968
•
•
•
•
•
Protein
Q8CCG3
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: false
•
•
•
•
•
Protein
D3YZ26
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
•
•
•
•
•
Publication
28792938 | J:249262
First Author: Li HB
Year: 2017
Journal: Nature
Title: m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.
Volume: 548
Issue: 7667
Pages: 338-342
•
•
•
•
•
Publication
29311632 | J:260174
First Author: Meakin PJ
Year: 2018
Journal: Sci Rep
Title: Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice.
Volume: 8
Issue: 1
Pages: 55
•
•
•
•
•
Publication
32603429 | J:295989
 
First Author: Fu Y
Year: 2020
Journal: Endocrinology
Title: Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus.
Volume: 161
Issue: 9
•
•
•
•
•
Publication
28465464 | J:243652
First Author: Sun Y
Year: 2017
Journal: J Exp Med
Title: Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos.
Volume: 214
Issue: 6
Pages: 1753-1767
•
•
•
•
•
Publication
25138272 | J:336958
 
First Author: Jiang Y
Year: 2014
Journal: J Neuroinflammation
Title: Etanercept restores normal insulin signal transduction in β2-adrenergic receptor knockout mice.
Volume: 11
Pages: 137
•
•
•
•
•
Publication
22658486 | J:185514
First Author: Esper L
Year: 2012
Journal: Am J Pathol
Title: Role of SOCS2 in modulating heart damage and function in a murine model of acute Chagas disease.
Volume: 181
Issue: 1
Pages: 130-40
•
•
•
•
•
Publication
28013147 | J:272140
 
First Author: Dhar-Mascareno M
Year: 2017
Journal: Int J Biochem Cell Biol
Title: Hexim1 heterozygosity stabilizes atherosclerotic plaque and decreased steatosis in ApoE null mice fed atherogenic diet.
Volume: 83
Pages: 56-64
•
•
•
•
•
Publication
19535626 | J:150117
First Author: Qin H
Year: 2009
Journal: J Immunol
Title: TGF-beta promotes Th17 cell development through inhibition of SOCS3.
Volume: 183
Issue: 1
Pages: 97-105
•
•
•
•
•
Publication
18322180 | J:132905
First Author: Tanaka K
Year: 2008
Journal: J Immunol
Title: Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads.
Volume: 180
Issue: 6
Pages: 3746-56
•
•
•
•
•
Publication
23114963 | J:194699
First Author: Hoene M
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: Interleukin-6 promotes myogenic differentiation of mouse skeletal muscle cells: role of the STAT3 pathway.
Volume: 304
Issue: 2
Pages: C128-36
•
•
•
•
•
Publication
16397521 | J:106773
First Author: Gallucci RM
Year: 2006
Journal: J Invest Dermatol
Title: IL-6 modulates alpha-smooth muscle actin expression in dermal fibroblasts from IL-6-deficient mice.
Volume: 126
Issue: 3
Pages: 561-8
•
•
•
•
•
Publication
27333268 | J:248875
First Author: Gavito AL
Year: 2016
Journal: PLoS One
Title: Chronic IL-6 Administration Desensitizes IL-6 Response in Liver, Causes Hyperleptinemia and Aggravates Steatosis in Diet-Induced-Obese Mice.
Volume: 11
Issue: 6
Pages: e0157956
•
•
•
•
•
Publication
15976028 | J:99865
First Author: McLoughlin RM
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.
Volume: 102
Issue: 27
Pages: 9589-94
•
•
•
•
•
Publication
18431520 | J:135184
First Author: Ernst M
Year: 2008
Journal: J Clin Invest
Title: STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.
Volume: 118
Issue: 5
Pages: 1727-38
•
•
•
•
•
Publication
24449804 | J:299124
First Author: Ju X
Year: 2014
Journal: J Am Heart Assoc
Title: IL-6 regulates extracellular matrix remodeling associated with aortic dilation in a fibrillin-1 hypomorphic mgR/mgR mouse model of severe Marfan syndrome.
Volume: 3
Issue: 1
Pages: e000476
•
•
•
•
•
Publication
29352287 | J:336614
First Author: Ramakrishna C
Year: 2018
Journal: PLoS Pathog
Title: IFNγ inhibits G-CSF induced neutrophil expansion and invasion of the CNS to prevent viral encephalitis.
Volume: 14
Issue: 1
Pages: e1006822
•
•
•
•
•
Publication
19699298 | J:164851
First Author: Clementi AH
Year: 2009
Journal: Biochim Biophys Acta
Title: Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling.
Volume: 1792
Issue: 11
Pages: 1062-72
•
•
•
•
•
Publication
29654210 | J:261461
First Author: Fahl SP
Year: 2018
Journal: J Immunol
Title: c-Myb Coordinates Survival and the Expression of Genes That Are Critical for the Pre-BCR Checkpoint.
Volume: 200
Issue: 10
Pages: 3450-3463
•
•
•
•
•
Publication
34996840 | J:322305
First Author: Kawahara E
Year: 2022
Journal: J Immunol
Title: TNF Receptor-Associated Factor 5 Limits IL-27 Receptor Signaling in CD4+ T Lymphocytes.
Volume: 208
Issue: 3
Pages: 642-650
•
•
•
•
•
Publication
30353127 | J:269763
First Author: Dalby MJ
Year: 2018
Journal: Sci Rep
Title: Diet induced obesity is independent of metabolic endotoxemia and TLR4 signalling, but markedly increases hypothalamic expression of the acute phase protein, SerpinA3N.
Volume: 8
Issue: 1
Pages: 15648
•
•
•
•
•
Publication
21778271 | J:181394
First Author: Yu CR
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Suppressor of cytokine signaling-1 (SOCS1) inhibits lymphocyte recruitment into the retina and protects SOCS1 transgenic rats and mice from ocular inflammation.
Volume: 52
Issue: 9
Pages: 6978-86
•
•
•
•
•
Publication
15671148 | J:110076
First Author: Kamezaki K
Year: 2005
Journal: Stem Cells
Title: Roles of Stat3 and ERK in G-CSF signaling.
Volume: 23
Issue: 2
Pages: 252-63
•
•
•
•
•
Publication
28122728 | J:240956
First Author: Rocha-Resende C
Year: 2017
Journal: Am J Physiol Cell Physiol
Title: Absence of suppressor of cytokine signaling 2 turns cardiomyocytes unresponsive to LIF-dependent increases in Ca2+ levels.
Volume: 312
Issue: 4
Pages: C478-C486
•
•
•
•
•
Publication
29626115 | J:261604
First Author: Zhang X
Year: 2018
Journal: J Exp Med
Title: Macrophage/microglial Ezh2 facilitates autoimmune inflammation through inhibition of Socs3.
Volume: 215
Issue: 5
Pages: 1365-1382
•
•
•
•
•
Publication
24091600 | J:210561
First Author: Li G
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Mechanisms of STAT3 activation in the liver of FXR knockout mice.
Volume: 305
Issue: 11
Pages: G829-37
•
•
•
•
•
Publication
19211725 | J:146841
First Author: Wang M
Year: 2009
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Estrogen receptor beta mediates increased activation of PI3K/Akt signaling and improved myocardial function in female hearts following acute ischemia.
Volume: 296
Issue: 4
Pages: R972-8
•
•
•
•
•
Publication
25896118 | J:298795
 
First Author: Buonfiglio DC
Year: 2015
Journal: Horm Behav
Title: Neuronal STAT5 signaling is required for maintaining lactation but not for postpartum maternal behaviors in mice.
Volume: 71
Pages: 60-8
•
•
•
•
•
Publication
32169845 | J:287182
First Author: Sesti-Costa R
Year: 2020
Journal: J Immunol
Title: Leukemia Inhibitory Factor Inhibits Plasmacytoid Dendritic Cell Function and Development.
Volume: 204
Issue: 8
Pages: 2257-2268
•
•
•
•
•
Publication
17556363 | J:124577
First Author: Cohen SE
Year: 2007
Journal: J Biol Chem
Title: High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice.
Volume: 282
Issue: 32
Pages: 23672-8
•
•
•
•
•
Publication
21873554 | J:189379
First Author: Jiang C
Year: 2011
Journal: Diabetes
Title: Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice.
Volume: 60
Issue: 10
Pages: 2484-95
•
•
•
•
•
Publication
28096257 | J:246076
First Author: Joo E
Year: 2017
Journal: Diabetes
Title: Inhibition of Gastric Inhibitory Polypeptide Receptor Signaling in Adipose Tissue Reduces Insulin Resistance and Hepatic Steatosis in High-Fat Diet-Fed Mice.
Volume: 66
Issue: 4
Pages: 868-879
•
•
•
•
•
Publication
27694475 | J:237419
First Author: Surolia R
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections.
Volume: 311
Issue: 5
Pages: L928-L940
•
•
•
•
•
Publication
23528817 | J:202414
First Author: Takekoshi T
Year: 2013
Journal: J Invest Dermatol
Title: CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis.
Volume: 133
Issue: 11
Pages: 2530-2537
•
•
•
•
•
Publication
32052456 | J:304269
First Author: Zahoor A
Year: 2020
Journal: J Cell Physiol
Title: Gas6 negatively regulates the Staphylococcus aureus-induced inflammatory response via TLR signaling in the mouse mammary gland.
Volume: 235
Issue: 10
Pages: 7081-7093
•
•
•
•
•
Publication
31455730 | J:279361
First Author: Ashouri JF
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis.
Volume: 116
Issue: 37
Pages: 18517-18527
•
•
•
•
•
Publication
30010888 | J:266678
First Author: Xiao Y
Year: 2018
Journal: Int Immunol
Title: Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells.
Volume: 30
Issue: 10
Pages: 457-470
•
•
•
•
•
Publication
17591906 | J:123272
First Author: Swiderski RE
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: Gene expression analysis of photoreceptor cell loss in bbs4-knockout mice reveals an early stress gene response and photoreceptor cell damage.
Volume: 48
Issue: 7
Pages: 3329-40
•
•
•
•
•
Publication
15199163 | J:91591
First Author: Brender C
Year: 2004
Journal: Mol Cell Biol
Title: SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function.
Volume: 24
Issue: 13
Pages: 6094-103
•
•
•
•
•
Publication
25957555 | J:251248
First Author: Jiao L
Year: 2015
Journal: Biochim Biophys Acta
Title: Sensitization to autoimmune hepatitis in group VIA calcium-independent phospholipase A2-null mice led to duodenal villous atrophy with apoptosis, goblet cell hyperplasia and leaked bile acids.
Volume: 1852
Issue: 8
Pages: 1646-57
•
•
•
•
•
Publication
28199020 | J:339228
First Author: Ghosh A
Year: 2017
Journal: J Neurochem
Title: Gemfibrozil, food and drug administration-approved lipid-lowering drug, increases longevity in mouse model of late infantile neuronal ceroid lipofuscinosis.
Volume: 141
Issue: 3
Pages: 423-435
•
•
•
•
•
Publication
25006249 | J:325170
First Author: Soki FN
Year: 2014
Journal: J Biol Chem
Title: Polarization of prostate cancer-associated macrophages is induced by milk fat globule-EGF factor 8 (MFG-E8)-mediated efferocytosis.
Volume: 289
Issue: 35
Pages: 24560-72
•
•
•
•
•
Publication
34755534 | J:333031
First Author: Han H
Year: 2022
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Loss of aryl hydrocarbon receptor suppresses the response of colonic epithelial cells to IL22 signaling by upregulating SOCS3.
Volume: 322
Issue: 1
Pages: G93-G106
•
•
•
•
•
Publication
22179221 | J:181729
First Author: Serrano-Marco L
Year: 2012
Journal: Diabetologia
Title: The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells.
Volume: 55
Issue: 3
Pages: 743-51
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom