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Search results 401 to 473 out of 473 for Srgap3

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:7619950
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7621456
Age: postnatal day 1
Specimen Label: Table 1 P1
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
Probe: MGI:7619950
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3791722
Pattern: Scattered
Stage: TS22
Assay Id: MGI:7621456
Age: embryonic day 14.5
Image: 5C
Note: Expression is in some scattered neurons of the ganglion layer.
Specimen Label: 5C
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:7619950
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3791721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7621456
Age: embryonic day 13.5
Note: Expression is in the mitral layer and granule cell layer.
Specimen Label: Table 1 E13.5
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
 
Probe: MGI:7619950
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3791722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7621456
Age: embryonic day 14.5
Note: Expression is in the mitral layer and granule cell layer.
Specimen Label: Table 1 E14.5
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
     
Probe: MGI:7619950
Assay Type: RNA in situ
Annotation Date: 2024-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3826128
Stage: TS28
Assay Id: MGI:7621456
Age: postnatal day 7
Specimen Label: Table 1 P7
Detected: false
Specimen Num: 26
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Publication
- | J:74945
   
First Author: Crowley MR
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Rho GTPase-activating protein mRNA, complete cds
Pages: AF338472
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Publication
17215396 | J:117303
First Author: Soderling SH
Year: 2007
Journal: J Neurosci
Title: A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory.
Volume: 27
Issue: 2
Pages: 355-65
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Publication
11672528 | J:72329
First Author: Wong K
Year: 2001
Journal: Cell
Title: Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
Volume: 107
Issue: 2
Pages: 209-21
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Publication
33514561 | J:333727
First Author: Rogg M
Year: 2021
Journal: J Am Soc Nephrol
Title: SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.
Volume: 32
Issue: 3
Pages: 563-579
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Publication
- | J:58777
     
First Author: Elliott R
Year: 2000
Journal: Personal Communication
Title: Chromosome Locations Based on RH mapping
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
12693553 | J:83413
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
24561795 | J:219259
 
First Author: Dai YK
Year: 2014
Journal: Mol Cell Neurosci
Title: A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1.
Volume: 60
Pages: 10-25
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Allele
Srgap3<em2Smoc> | MGI:7292585
Name: SLIT-ROBO Rho GTPase activating protein 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
22467852 | -
First Author: Coutinho-Budd J
Year: 2012
Journal: J Cell Sci
Title: The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.
Volume: 125
Issue: Pt 14
Pages: 3390-401
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Publication
22159416 | -
First Author: Endris V
Year: 2011
Journal: J Cell Sci
Title: SrGAP3 interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions.
Volume: 124
Issue: Pt 23
Pages: 3941-55
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Publication
23505444 | -
First Author: Ma Y
Year: 2013
Journal: PLoS One
Title: The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells.
Volume: 8
Issue: 3
Pages: e57865
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Strain
MGI:6771195 | C57BL/6JSmoc-Srgap3<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein
Q812A2
Organism: Mus musculus/domesticus
Length: 1099  
Fragment?: false
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Allele
Srgap3<em1Smoc> | MGI:7292584
Name: SLIT-ROBO Rho GTPase activating protein 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6771194 | C57BL/6JSmoc-Srgap3<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
22559944 | J:185134
First Author: Charrier C
Year: 2012
Journal: Cell
Title: Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.
Volume: 149
Issue: 4
Pages: 923-35
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Publication
28333212 | -
First Author: Sporny M
Year: 2017
Journal: Mol Biol Evol
Title: Structural History of Human SRGAP2 Proteins.
Volume: 34
Issue: 6
Pages: 1463-1478
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Protein Domain
IPR030252 | srGAP2
Type: Family
Description: The SLIT-ROBO Rho GTPase-activating protein (srGAP) family consists of four members: srGAP1, -2, -3 and -4. They contain F-BAR, RhoGAP and SH3 domains. Their RhoGAP domain is involved in negative regulation of Rho GTPase activities important for cytoskeleton rearrangement []. The srGAP family members have an "inverse F-BAR"or IF-BAR domain that is distinct from other F-BAR domains such as FBP17. They are multifunctional adaptor proteins involved in various aspects of neuronal development [].srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells []. This entry also includes human srGAP2 duplication gene, SLIT-ROBO Rho GTPase-activating protein 2B and 2C (srGAP2B/C) []. srGAP2C encodes a truncated F-BAR domain protein that dimerises with srGAP2 to inhibit its function and thruogh this interaction with srGAP2 is involved in dendritic spine maturation [].
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Protein Domain
IPR035648 | srGAP1/2/3_SH3
Type: Domain
Description: This entry represents the SH3 domain found in srGAP proteins 1, 2 and 3. srGAP1 (also called ARHGAP13) is a key GTPase activating protein (GAP) downstream of Slit-Robo pathway, and has been shown to inhibit neuronal migration and glioma cell invasion by reducing the activation of Cdc42 []. srGAP2 (ARHGAP34) regulates neuronal morphogenesis through the ability of its F-BAR domain to regulate membrane deformation and induce filopodia formation []. srGAP3 (ARHGAP14) interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions []. The SLIT-ROBO Rho GTPase-activating protein (srGAP) family consists of four members: srGAP1, -2, -3 and -4. They contain F-BAR, RhoGAP and SH3 domains. Their RhoGAP domain is involved in negative regulation of Rho GTPase activities important for cytoskeleton rearrangement []. The srGAP family members have an "inverse F-BAR"or IF-BAR domain that is distinct from other F-BAR domains such as FBP17. They are multifunctional adaptor proteins involved in various aspects of neuronal development [].
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Publication
20810653 | -
First Author: Guo S
Year: 2010
Journal: J Biol Chem
Title: srGAP2 arginine methylation regulates cell migration and cell spreading through promoting dimerization.
Volume: 285
Issue: 45
Pages: 35133-41
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Protein
A0A087WS73
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: true
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Protein
Q3TSN4
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
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Protein
A0A087WS59
Organism: Mus musculus/domesticus
Length: 451  
Fragment?: true
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Protein
A0A087WSQ1
Organism: Mus musculus/domesticus
Length: 649  
Fragment?: true
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Protein
Q91Z68
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
Q3UPB8
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
A0A087WRV4
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
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Protein
A0A087WNR5
Organism: Mus musculus/domesticus
Length: 55  
Fragment?: true
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Protein
Q91Z67
Organism: Mus musculus/domesticus
Length: 1071  
Fragment?: false
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Protein
A0A087WNM1
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Protein
A0A2X0SZ45
Organism: Mus musculus/domesticus
Length: 1106  
Fragment?: true
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Protein
Q91Z69
Organism: Mus musculus/domesticus
Length: 1062  
Fragment?: false
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Protein
D3YZW1
Organism: Mus musculus/domesticus
Length: 1085  
Fragment?: false
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Protein
E9QN14
Organism: Mus musculus/domesticus
Length: 1075  
Fragment?: false
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Protein
F8VPQ4
Organism: Mus musculus/domesticus
Length: 1099  
Fragment?: false
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