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Search results 401 to 455 out of 455 for Sstr1

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Type

Details

Score

Publication

- | J:46439

First Author:	Freeman TC
Year:	1998
Journal:	MGI Direct Data Submission
Title:	Expression Mapping of Mouse Genes

•

Publication

- | J:15839

First Author:	International Committee on Standardized Genetic Nomenclature for Mice
Year:	1993

Title:	Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols

•

Publication

- | J:237616

First Author:	MGI and IMPC
Year:	2017
Journal:	MGI Direct Data Submission
Title:	MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)

•

Publication

- | J:94790

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Mouse Synonym Curation

•

Publication

- | J:346132

First Author:	The Gene Ontology Consortium
Year:	2016

Title:	Automatic assignment of GO terms using logical inference, based on on inter-ontology links

•

Publication

24952961 | J:215487

First Author:	Thompson CL
Year:	2014
Journal:	Neuron
Title:	A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume:	83
Issue:	2
Pages:	309-323

•

Publication

- | J:211773

First Author:	Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year:	2014
Journal:	Database Release
Title:	Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database

•

Publication

- | J:155856

First Author:	The Gene Ontology Consortium
Year:	2014

Title:	Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs

•

Publication

16602821 | J:162220

First Author:	Magdaleno S
Year:	2006
Journal:	PLoS Biol
Title:	BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume:	4
Issue:	4
Pages:	e86

•

Publication

38355793 | J:345621

First Author:	Adams DJ
Year:	2024
Journal:	Nature
Title:	Genetic determinants of micronucleus formation in vivo.
Volume:	627
Issue:	8002
Pages:	130-136

•

Publication

- | J:23000

First Author:	MGD Nomenclature Committee
Year:	1995

Title:	Nomenclature Committee Use

•

Publication

- | J:293217

First Author:	GemPharmatech
Year:	2020

Title:	GemPharmatech Website.

•

Publication

- | J:342605

First Author:	GOA curators
Year:	2016

Title:	Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

•

Publication

12466851 | J:80000

First Author:	Okazaki Y
Year:	2002
Journal:	Nature
Title:	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume:	420
Issue:	6915
Pages:	563-73

•

Publication

21267068 | J:153498

First Author:	Diez-Roux G
Year:	2011
Journal:	PLoS Biol
Title:	A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume:	9
Issue:	1
Pages:	e1000582

•

Publication

- | J:157972

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2010
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).

•

Publication

- | J:57747

First Author:	MGI Genome Annotation Group and UniGene Staff
Year:	2015
Journal:	Database Download
Title:	MGI-UniGene Interconnection Effort

•

Publication

- | J:161428

First Author:	Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year:	2010

Title:	Annotation inferences using phylogenetic trees

•

Publication

- | J:63103

First Author:	Mouse Genome Database and National Center for Biotechnology Information
Year:	2000
Journal:	Database Release
Title:	Entrez Gene Load

•

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

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Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

•

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

•

Allele

Sstr1<em1Smoc> | MGI:7292595

Name:	somatostatin receptor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

•

GXD Expression

Probe:	MGI:7264342
Assay Type:	Immunohistochemistry
Annotation Date:	2022-04-26
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:1759728
Pattern:	Not Specified
Stage:	TS28
Assay Id:	MGI:7264355
Age:	postnatal adult

Note:	No difference between wild type and Sstr1 knockout mice.
Specimen Label:	5e
Detected:	true
Specimen Num:	6

•

GXD Expression

Probe:	MGI:7264342
Assay Type:	Immunohistochemistry
Annotation Date:	2022-04-26
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:1759728
Pattern:	Not Specified
Stage:	TS28
Assay Id:	MGI:7264355
Age:	postnatal adult

Note:	No difference between wild type and Sstr1 knockout mice.
Specimen Label:	5e
Detected:	true
Specimen Num:	6

•

GXD Expression

Probe:	MGI:7264340
Assay Type:	Immunohistochemistry
Annotation Date:	2022-04-26
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:1759728
Pattern:	Not Specified
Stage:	TS28
Assay Id:	MGI:7264354
Age:	postnatal adult

Note:	No difference between wild type and Sstr1 knockout mice.
Specimen Label:	5b
Detected:	true
Specimen Num:	6

•

GXD Expression

Probe:	MGI:7264340
Assay Type:	Immunohistochemistry
Annotation Date:	2022-04-26
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:1759728
Pattern:	Not Specified
Stage:	TS28
Assay Id:	MGI:7264354
Age:	postnatal adult

Note:	No difference between wild type and Sstr1 knockout mice.
Specimen Label:	5b
Detected:	true
Specimen Num:	6

•

GXD Expression

Probe:	MGI:7264340
Assay Type:	Immunohistochemistry
Annotation Date:	2022-04-26
Strength:	Present
Sex:	Not Specified
Emaps:	EMAPS:1759728
Pattern:	Not Specified
Stage:	TS28
Assay Id:	MGI:7264354
Age:	postnatal adult

Note:	No difference between wild type and Sstr1 knockout mice.
Specimen Label:	5b
Detected:	true
Specimen Num:	6

•

Strain

MGI:6429601 | C57BL/6JSmoc-Sstr1<em1Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

•

Publication

7907795 | -

First Author:	Buscail L
Year:	1994
Journal:	Proc Natl Acad Sci U S A
Title:	Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2.
Volume:	91
Issue:	6
Pages:	2315-9

•

Publication

1328199 | J:2683

First Author:	Yasuda K
Year:	1992
Journal:	J Biol Chem
Title:	Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylylcyclase.
Volume:	267
Issue:	28
Pages:	20422-8

•

Publication

12742651 | J:119042

First Author:	Perez J
Year:	2003
Journal:	J Neuroimmunol
Title:	Somatostatin binds to murine macrophages through two distinct subsets of receptors.
Volume:	138
Issue:	1-2
Pages:	38-44

•

Publication

16026801 | J:106394

First Author:	Wang XP
Year:	2005
Journal:	J Surg Res
Title:	The effect of global SSTR5 gene ablation on the endocrine pancreas and glucose regulation in aging mice.
Volume:	129
Issue:	1
Pages:	64-72

•

Publication

18406829 | -

First Author:	Patel YC
Year:	1997
Journal:	Trends Endocrinol Metab
Title:	Somatostatin receptors.
Volume:	8
Issue:	10
Pages:	398-405

•

Protein Domain

IPR001116 | Somatstn_rcpt_1

Type:

Family

Description:

Somatostatin (SST), also known as somatotropin release-inhibiting factor (SRIF), is a hypothalamic hormone, a pancreatic hormone, and a central and peripheral neurotransmitter. Somatostatin has a wide distribution throughout the central nervous system (CNS) as well as in peripheral tissues, for example in the pituitary, pancreas and stomach. The various actions of somatostatin are mediated by a family of rhodopsin-like G protein-coupled receptors, which comprise of five distinct subtypes: Somatostatin receptor 1 (SSTR1), Somatostatin receptor 2 (SSTR2), Somatostatin receptor 3 (SSTR3), Somatostatin receptor 4 (SSTR4) and Somatostatin receptor 5 (SSTR5) [, , ]. These subtypes are widely expressed in many tissues [, , , , , ], and frequently multiple subtypes coexist in the same cell []. The somatostatin receptor subtypes also share common signalling pathways, such as the inhibition of adenylyl cyclase [, ], activation of phosphotyrosine phosphatase (PTP), and modulation of mitogen-activated protein kinase (MAPK) through G protein-dependent mechanisms. Some of the subtypes are also coupled to inward rectifying K+ channels (SSTR2, SSTR3, SSTR4, SSTR5) [, ], to voltage-dependent Ca2+ channels (SSTR1, SSTR2) [], to an Na+/H+ exchanger (SSTR1), AMPA/kainate glutamate channels (SSTR1, SSTR2), phospholipase C (SSTR2, SSTR5), and phospholipase A2 (SSTR4) []. Amongst the wide spectrum of somatostatin effects, several biological responses have been identified that display absolute or relative subtype selectivity. These include GH secretion (SSTR2 and 5), insulin secretion (SSTR5), glucagon secretion (SSTR2), and immune responses (SSTR2) [].This entry represents SSTR1 []. In humans, it is expressed at high levels in the jejunum and stomach, with lower levels in the pancreas, colon and kidney, but it is absent in the brain. Conversely, in rodent tissue, high levels are found in the brain, but are absent in peripheral tissues []. All five human somatostatin receptors expressed in COS-7 cells are coupled to activation of phosphoinositide (PI)-specific PLC-beta; and Ca2+ mobilisation via pertussis toxin-sensitive G protein(s) with an order of potency of SSTR5 >SSTR2 >SSTR3 >SSTR4 >SSTR1 [].

•

Protein

P30873

Organism:	Mus musculus/domesticus
Length:	391
Fragment?:	false

•

Protein

Q543T0

Organism:	Mus musculus/domesticus
Length:	391
Fragment?:	false

•

Publication

10433861 | -

First Author:	Patel YC
Year:	1999
Journal:	Front Neuroendocrinol
Title:	Somatostatin and its receptor family.
Volume:	20
Issue:	3
Pages:	157-98

•

Publication

8243278 | -

First Author:	Bruno JF
Year:	1993
Journal:	Endocrinology
Title:	Tissue distribution of somatostatin receptor subtype messenger ribonucleic acid in the rat.
Volume:	133
Issue:	6
Pages:	2561-7

•

Publication

8078491 | -

First Author:	O'Carroll AM
Year:	1994
Journal:	Mol Pharmacol
Title:	Characterization of cloned human somatostatin receptor SSTR5.
Volume:	46
Issue:	2
Pages:	291-8

•

Publication

8483934 | -

First Author:	Rohrer L
Year:	1993
Journal:	Proc Natl Acad Sci U S A
Title:	Cloning and characterization of a fourth human somatostatin receptor.
Volume:	90
Issue:	9
Pages:	4196-200

•

Publication

15361490 | -

First Author:	Gugger M
Year:	2004
Journal:	Gut
Title:	Cellular detection of sst2A receptors in human gastrointestinal tissue.
Volume:	53
Issue:	10
Pages:	1431-6

•

Publication

10598790 | -

First Author:	Siehler S
Year:	1999
Journal:	Naunyn Schmiedebergs Arch Pharmacol
Title:	Characterisation of human recombinant somatostatin receptors. 3. Modulation of adenylate cyclase activity.
Volume:	360
Issue:	5
Pages:	510-21

•

Publication

7538774 | -

First Author:	Law SF
Year:	1995
Journal:	Cell Signal
Title:	Somatostatin receptor activation of cellular effector systems.
Volume:	7
Issue:	1
Pages:	1-8

•

Publication

9426226 | -

First Author:	Kreienkamp HJ
Year:	1997
Journal:	FEBS Lett
Title:	Coupling of rat somatostatin receptor subtypes to a G-protein gated inwardly rectifying potassium channel (GIRK1).
Volume:	419
Issue:	1
Pages:	92-4

•

Publication

8684611 | -

First Author:	Tallent M
Year:	1996
Journal:	Neuroscience
Title:	Somatostatin receptor subtypes SSTR2 and SSTR5 couple negatively to an L-type Ca2+ current in the pituitary cell line AtT-20.
Volume:	71
Issue:	4
Pages:	1073-81

•

Publication

8034040 | -

First Author:	Akbar M
Year:	1994
Journal:	FEBS Lett
Title:	Phospholipase C activation and Ca2+ mobilization by cloned human somatostatin receptor subtypes 1-5, in transfected COS-7 cells.
Volume:	348
Issue:	2
Pages:	192-6

•

Publication

14507421 | -

First Author:	Møller LN
Year:	2003
Journal:	Biochim Biophys Acta
Title:	Somatostatin receptors.
Volume:	1616
Issue:	1
Pages:	1-84

•

Publication

7792934 | -

First Author:	Hoyer D
Year:	1995
Journal:	Trends Pharmacol Sci
Title:	Classification and nomenclature of somatostatin receptors.
Volume:	16
Issue:	3
Pages:	86-8

•

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