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Search results 401 to 500 out of 1340 for Tlr9

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Type Details Score
Publication
First Author: Simmons DP
Year: 2010
Journal: J Immunol
Title: Mycobacterium tuberculosis and TLR2 agonists inhibit induction of type I IFN and class I MHC antigen cross processing by TLR9.
Volume: 185
Issue: 4
Pages: 2405-15
Publication
First Author: Dupont A
Year: 2016
Journal: PLoS Pathog
Title: Age-Dependent Susceptibility to Enteropathogenic Escherichia coli (EPEC) Infection in Mice.
Volume: 12
Issue: 5
Pages: e1005616
Publication
First Author: Panigrahi S
Year: 2013
Journal: Circ Res
Title: Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis.
Volume: 112
Issue: 1
Pages: 103-12
Publication
First Author: Zhu J
Year: 2009
Journal: J Clin Invest
Title: The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice.
Volume: 119
Issue: 8
Pages: 2388-98
Publication
First Author: Liu YC
Year: 2012
Journal: J Immunol
Title: TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9.
Volume: 188
Issue: 3
Pages: 1019-26
Publication
First Author: Schell SL
Year: 2017
Journal: J Immunol
Title: Mer Receptor Tyrosine Kinase Signaling Prevents Self-Ligand Sensing and Aberrant Selection in Germinal Centers.
Volume: 199
Issue: 12
Pages: 4001-4015
Publication
First Author: Umiker BR
Year: 2014
Journal: Eur J Immunol
Title: Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus.
Volume: 44
Issue: 5
Pages: 1503-16
Publication
First Author: Muruve DA
Year: 2008
Journal: Nature
Title: The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response.
Volume: 452
Issue: 7183
Pages: 103-7
Publication
First Author: Nakamura K
Year: 2008
Journal: J Immunol
Title: Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.
Volume: 180
Issue: 6
Pages: 4067-74
Publication
First Author: Schamber-Reis BL
Year: 2013
Journal: J Biol Chem
Title: UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.
Volume: 288
Issue: 10
Pages: 7127-36
Publication
First Author: McAlpine W
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function.
Volume: 115
Issue: 49
Pages: E11523-E11531
Publication
First Author: González-Navajas JM
Year: 2010
Journal: J Exp Med
Title: Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.
Volume: 207
Issue: 13
Pages: 2799-807
Publication
First Author: Uchida T
Year: 2007
Journal: J Immunol
Title: Variable requirement of dendritic cells for recruitment of NK and T cells to different TLR agonists.
Volume: 178
Issue: 6
Pages: 3886-92
Publication
First Author: Khan S
Year: 2007
Journal: J Biol Chem
Title: Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells.
Volume: 282
Issue: 29
Pages: 21145-59
Publication
First Author: Mitchell D
Year: 2010
Journal: Mol Immunol
Title: Regulation of Toll-like receptor-induced chemokine production in murine dendritic cells by mitogen-activated protein kinases.
Volume: 47
Issue: 11-12
Pages: 2065-73
Publication
First Author: Delale T
Year: 2005
Journal: J Immunol
Title: MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo.
Volume: 175
Issue: 10
Pages: 6723-32
Publication
First Author: Kumar SRP
Year: 2024
Journal: Mol Ther
Title: TLR9-independent CD8(+) T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling.
Volume: 32
Issue: 2
Pages: 325-339
Publication
First Author: Drennan MB
Year: 2005
Journal: J Immunol
Title: The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent.
Volume: 175
Issue: 4
Pages: 2501-9
Publication  
First Author: Li N
Year: 2024
Journal: Viruses
Title: Redundancy in Innate Immune Pathways That Promote CD8(+) T-Cell Responses in AAV1 Muscle Gene Transfer.
Volume: 16
Issue: 10
Publication
First Author: Baccarella A
Year: 2013
Journal: Infect Immun
Title: Toll-like receptor 7 mediates early innate immune responses to malaria.
Volume: 81
Issue: 12
Pages: 4431-42
Publication  
First Author: Shimizu K
Year: 2019
Journal: Front Immunol
Title: Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN.
Volume: 10
Pages: 1450
Publication
First Author: Prantner D
Year: 2010
Journal: J Immunol
Title: Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infection.
Volume: 184
Issue: 5
Pages: 2551-60
Publication
First Author: Lee KG
Year: 2008
Journal: J Biol Chem
Title: Bruton's tyrosine kinase separately regulates NFkappaB p65RelA activation and cytokine interleukin (IL)-10/IL-12 production in TLR9-stimulated B Cells.
Volume: 283
Issue: 17
Pages: 11189-98
Publication
First Author: Ferrero MC
Year: 2014
Journal: Infect Immun
Title: Key role of Toll-like receptor 2 in the inflammatory response and major histocompatibility complex class ii downregulation in Brucella abortus-infected alveolar macrophages.
Volume: 82
Issue: 2
Pages: 626-39
Publication
First Author: Hassan F
Year: 2012
Journal: PLoS One
Title: Moraxella catarrhalis activates murine macrophages through multiple toll like receptors and has reduced clearance in lungs from TLR4 mutant mice.
Volume: 7
Issue: 5
Pages: e37610
Publication
First Author: Heimesaat MM
Year: 2010
Journal: Gut
Title: MyD88/TLR9 mediated immunopathology and gut microbiota dynamics in a novel murine model of intestinal graft-versus-host disease.
Volume: 59
Issue: 8
Pages: 1079-87
Publication
First Author: Luo X
Year: 2019
Journal: J Neurosci
Title: Macrophage Toll-like Receptor 9 Contributes to Chemotherapy-Induced Neuropathic Pain in Male Mice.
Volume: 39
Issue: 35
Pages: 6848-6864
Publication
First Author: Aldrich AL
Year: 2020
Journal: J Neuroinflammation
Title: TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection.
Volume: 17
Issue: 1
Pages: 114
Publication
First Author: Blasius AL
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells.
Volume: 107
Issue: 46
Pages: 19973-8
Publication
First Author: Henao-Mejia J
Year: 2012
Journal: Nature
Title: Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.
Volume: 482
Issue: 7384
Pages: 179-85
Publication
First Author: Kaul D
Year: 2012
Journal: PLoS One
Title: Expression of Toll-like receptors in the developing brain.
Volume: 7
Issue: 5
Pages: e37767
Publication  
First Author: Gao Y
Year: 2021
Journal: Int J Mol Sci
Title: YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes.
Volume: 22
Issue: 13
Publication  
First Author: Hayashi T
Year: 2018
Journal: Front Immunol
Title: DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination.
Volume: 9
Pages: 2619
Publication  
First Author: Bussey KA
Year: 2019
Journal: J Virol
Title: Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 Infection.
Volume: 93
Issue: 3
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Hemmi H
Year: 2000
Journal: Nature
Title: A Toll-like receptor recognizes bacterial DNA.
Volume: 408
Issue: 6813
Pages: 740-5
Publication
First Author: Liu X
Year: 2007
Journal: J Immunol
Title: Autoantigen-B cell antigen receptor interactions that regulate expression of B cell antigen receptor Loci.
Volume: 178
Issue: 8
Pages: 5035-47
Publication
First Author: Akkaya M
Year: 2018
Journal: Nat Immunol
Title: Second signals rescue B cells from activation-induced mitochondrial dysfunction and death.
Volume: 19
Issue: 8
Pages: 871-884
Publication      
First Author: Blasius AL
Year: 2009
Journal: MGI Direct Data Submission
Title: Record for "CpG6", updated April 29, 2009
Publication      
First Author: Sun L
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Asura (Last updated March 25, 2015)
Publication
First Author: Hannestad K
Year: 2017
Journal: J Immunol
Title: A Nonadjuvanted IgG2a Monoclonal Antibody against Nucleosomes Elicits Potent T Cell-Dependent, Idiotype-Specific IgG1 Responses and Glomerular IgG1/IgG2a Deposits in Normal Mice.
Volume: 199
Issue: 2
Pages: 489-500
Publication
First Author: Haas T
Year: 2009
Journal: Immunology
Title: Sequence independent interferon-alpha induction by multimerized phosphodiester DNA depends on spatial regulation of Toll-like receptor-9 activation in plasmacytoid dendritic cells.
Volume: 126
Issue: 2
Pages: 290-8
Publication
First Author: Tanaka M
Year: 2012
Journal: Infect Immun
Title: Toll-like receptor 9-dependent activation of bone marrow-derived dendritic cells by URA5 DNA from Cryptococcus neoformans.
Volume: 80
Issue: 2
Pages: 778-86
Publication
First Author: Zhang P
Year: 2024
Journal: Sci Immunol
Title: Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA.
Volume: 9
Issue: 96
Pages: eadj5465
Publication
First Author: Tran N
Year: 2007
Journal: J Clin Endocrinol Metab
Title: Toll-like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation.
Volume: 92
Issue: 7
Pages: 2773-83
Publication
First Author: Emran TB
Year: 2018
Journal: J Immunol
Title: Baculovirus-Induced Fast-Acting Innate Immunity Kills Liver-Stage Plasmodium.
Volume: 201
Issue: 8
Pages: 2441-2451
Publication
First Author: Martino AT
Year: 2011
Journal: Blood
Title: The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver.
Volume: 117
Issue: 24
Pages: 6459-68
Publication
First Author: Lahoud MH
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: DEC-205 is a cell surface receptor for CpG oligonucleotides.
Volume: 109
Issue: 40
Pages: 16270-5
Publication
First Author: Collins C
Year: 2008
Journal: J Immunol
Title: Activation of gamma delta T cells by Borrelia burgdorferi is indirect via a TLR- and caspase-dependent pathway.
Volume: 181
Issue: 4
Pages: 2392-8
Publication
First Author: Bogdan C
Year: 2009
Journal: J Immunol
Title: Comment on "TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions".
Volume: 183
Issue: 11
Pages: 6859; author reply 6859
Publication
First Author: Kim TH
Year: 2018
Journal: Sci Rep
Title: CpG-DNA exerts antibacterial effects by protecting immune cells and producing bacteria-reactive antibodies.
Volume: 8
Issue: 1
Pages: 16236
Publication
First Author: Yoshida H
Year: 2011
Journal: Free Radic Biol Med
Title: Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice.
Volume: 51
Issue: 2
Pages: 424-31
Publication      
First Author: Brandl K
Year: 2009
Journal: MGI Direct Data Submission 2009
Title: Record for "CpG7", updated November 9, 2009
Publication  
First Author: Thomalla M
Year: 2022
Journal: Int J Mol Sci
Title: Toll-like Receptor 7 (TLR7) Is Expressed in Adipocytes and the Pharmacological TLR7 Agonist Imiquimod and Adipocyte-Derived Cell-Free Nucleic Acids (cfDNA) Regulate Adipocyte Function.
Volume: 23
Issue: 15
Publication
First Author: Shimosato T
Year: 2003
Journal: Biochim Biophys Acta
Title: Swine Toll-like receptor 9(1) recognizes CpG motifs of human cell stimulant.
Volume: 1627
Issue: 1
Pages: 56-61
Publication
First Author: Bartz H
Year: 2006
Journal: Blood
Title: Involvement of suppressors of cytokine signaling in toll-like receptor-mediated block of dendritic cell differentiation.
Volume: 108
Issue: 13
Pages: 4102-8
Publication
First Author: Flierl U
Year: 2015
Journal: J Exp Med
Title: Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators.
Volume: 212
Issue: 2
Pages: 129-37
Publication  
First Author: Einwächter H
Year: 2020
Journal: Front Immunol
Title: The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment.
Volume: 11
Pages: 1627
Publication  
First Author: Zheng H
Year: 2021
Journal: Front Cell Dev Biol
Title: Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury.
Volume: 9
Pages: 641527
GXD Expression      
Probe: MGI:4867534
Assay Type: RT-PCR
Annotation Date: 2011-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287422
Stage: TS22
Assay Id: MGI:4867544
Age: embryonic day 14.0
Specimen Label: E14
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4867534
Assay Type: RT-PCR
Annotation Date: 2011-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287424
Stage: TS24
Assay Id: MGI:4867544
Age: embryonic day 16.0
Specimen Label: E16
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4867534
Assay Type: RT-PCR
Annotation Date: 2011-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287426
Stage: TS26
Assay Id: MGI:4867544
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4867534
Assay Type: RT-PCR
Annotation Date: 2011-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287427
Stage: TS27
Assay Id: MGI:4867544
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4867530
Assay Type: Western blot
Annotation Date: 2011-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578028
Stage: TS28
Assay Id: MGI:4867546
Age: postnatal
Specimen Label: Mouse Ctrl
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4867534
Assay Type: RT-PCR
Annotation Date: 2011-01-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578028
Stage: TS28
Assay Id: MGI:4867552
Age: postnatal
Specimen Label: Ctrl
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7334826
Age: embryonic day 13.0
Image: 1
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:7334826
Age: embryonic day 14.0
Image: 1
Specimen Label: E14
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7334826
Age: embryonic day 15.0
Image: 1
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:7334826
Age: embryonic day 16.0
Image: 1
Specimen Label: E16
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7334826
Age: embryonic day 17.0
Image: 1
Specimen Label: E17
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7334826
Age: embryonic day 18.0
Image: 1
Specimen Label: E18
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:7334826
Age: embryonic day 19.0
Image: 1
Specimen Label: E19
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7334826
Age: postnatal day 0
Image: 1
Specimen Label: P0
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334826
Age: postnatal day 4
Image: 1
Specimen Label: P4
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334826
Age: postnatal day 8
Image: 1
Specimen Label: P8
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334826
Age: postnatal day 12
Image: 1
Specimen Label: P12
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:7334817
Assay Type: RT-PCR
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7334826
Age: postnatal month 5
Image: 1
Specimen Label: P5m
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:7334806
Assay Type: RNA in situ
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7334833
Age: postnatal day 12
Image: 2B Neocortex
Specimen Label: 2B Neocortex
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7334806
Assay Type: RNA in situ
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7334833
Age: embryonic day 16.0
Image: 2D E16
Note: Expression increased from embryonic to postnatal stages until adult levels were reached.
Specimen Label: 2D E16
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7334806
Assay Type: RNA in situ
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7334833
Age: postnatal day 0
Image: 2D P0
Note: Expression increased from embryonic to postnatal stages until adult levels.
Specimen Label: 2D P0
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:7334806
Assay Type: RNA in situ
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7334833
Age: postnatal day 12
Image: 2D P12
Note: Expression increased from embryonic to postnatal stages until adult levels.
Specimen Label: 2D P12
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:7334806
Assay Type: RNA in situ
Annotation Date: 2022-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7334833
Age: postnatal month 5
Image: 2D P5m
Note: Expression increased from embryonic to postnatal stages until adult levels were reached.
Specimen Label: 2D P5m
Detected: true
Specimen Num: 6