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Search results 401 to 500 out of 536 for Tmsb4x

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0.056s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Nba10/Nba10 Yaa/?
Background: C57BL/6-Nba2 Yaa
Zygosity: cx
Has Mutant Allele: true
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•
•
•
•
Genotype
Genotype
Symbol: Yaa/?
Background: (C57BL/6J x BXSB)F1
Zygosity: ot
Has Mutant Allele: true
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•
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•
Genotype
Genotype
Symbol: Yaa/?
Background: involves: BXSB * NZB
Zygosity: ot
Has Mutant Allele: true
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•
•
Genotype
Genotype
Symbol: Yaa/?
Background: BXSB/MpJ
Zygosity: ot
Has Mutant Allele: true
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•
Genotype
Genotype
Symbol: Yaa/?
Background: (NZW x SB)F1
Zygosity: ot
Has Mutant Allele: true
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•
Genotype
Genotype
Symbol: Yaa/?
Background: (NZW x BXSB)F1
Zygosity: ot
Has Mutant Allele: true
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•
Genotype
Genotype
Symbol: Yaa/?
Background: BXSB/MpJScr
Zygosity: ot
Has Mutant Allele: true
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•
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•
•
Genotype
Genotype
Symbol: ll/ll Yaa/?
Background: BXSB/MpJScr-ll
Zygosity: cx
Has Mutant Allele: true
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•
•
•
•
Genotype
Genotype
Symbol: Yaa/?
Background: (NZB x BXSB)F1
Zygosity: ot
Has Mutant Allele: true
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•
Genotype
Genotype
Symbol: Yaa/?
Background: (SJL/J x BXSB)F1
Zygosity: ot
Has Mutant Allele: true
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•
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•
Genotype
Genotype
Symbol: Yaa/?
Background: (NZB x B6.SB/Le-Yaa)F1
Zygosity: ot
Has Mutant Allele: true
•
•
•
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•
Genotype
Genotype
Symbol: Yaa/?
Background: B6.SB-Yaa/J
Zygosity: ot
Has Mutant Allele: true
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•
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•
Genotype
Genotype
Symbol: Tg(Tlr7)1Boll/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Tg(Tlr7)6Boll/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: B2m/B2m Yaa/?
Background: BXSB.129P2(B6)-B2m/Dcr
Zygosity: cx
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Il15/Il15 Yaa/?
Background: BXSB.B6-Il15/Dcr
Zygosity: cx
Has Mutant Allele: true
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•
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•
Genotype
Genotype
Symbol: Tcra/Tcra Yaa/?
Background: BXSB.129P2(Cg)-Tcra/Theo
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:5507705 | BXSB.129X1-Fcgrt<tm1Dcr>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5564648 | B6.Cg-Btk<m1Anu> Yaa/AnuApb
Attribute String: chemically induced mutation, congenic, mutant strain
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Strain
MGI:6094245 | BXSB.129X1-Fcgrt<tm1Dcr>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5504649 | BXSB.129S2(B6)-Cd8a<tm1Mak>/4DcrJ
Attribute String: targeted mutation, mutant strain, congenic, spontaneous mutation
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Strain
MGI:2174224 | BXSB.129S2(B6)-Cd8a<tm1Mak>/4Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2174222 | BXSB.129S2(B6)-Cd8a<tm1Mak>/1Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2174225 | BXSB.129S2(B6)-Ighm<tm1Cgn>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2174221 | BXSB.129S2(B6)-Tap1<tm1Arp>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Publication
34039637 | J:312203
     
First Author: Schell SL
Year: 2021
Journal: J Immunol
Title: Context-Dependent miR-21 Regulation of TLR7-Mediated Autoimmune and Foreign Antigen-Driven Antibody-Forming Cell and Germinal Center Responses.
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•
Publication
10604990 | J:112421
First Author: Kono DH
Year: 2000
Journal: J Immunol
Title: Development of lupus in BXSB mice is independent of IL-4.
Volume: 164
Issue: 1
Pages: 38-42
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•
•
Publication
7835973 | J:21189
First Author: Rosenblatt N
Year: 1994
Journal: Immunology
Title: The Yaa gene-dependent B-cell deficiency worsens the generalized lymphadenopathy and autoimmunity of C57BL/6-gld male mice.
Volume: 83
Issue: 3
Pages: 476-83
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Publication
27228057 | J:252479
First Author: Wu YY
Year: 2016
Journal: PLoS One
Title: BANK1 Regulates IgG Production in a Lupus Model by Controlling TLR7-Dependent STAT1 Activation.
Volume: 11
Issue: 5
Pages: e0156302
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Publication
9862363 | J:52110
First Author: Santiago ML
Year: 1998
Journal: Eur J Immunol
Title: Linkage of a major quantitative trait locus to Yaa gene-induced lupus-like nephritis in (NZW x C57BL/6)F1 mice.
Volume: 28
Issue: 12
Pages: 4257-67
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Publication
15634937 | J:95829
First Author: Kikuchi S
Year: 2005
Journal: J Immunol
Title: Differential role of three major New Zealand Black-derived loci linked with Yaa-induced murine lupus nephritis.
Volume: 174
Issue: 2
Pages: 1111-7
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Publication
10841565 | J:62719
First Author: Morel L
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.
Volume: 97
Issue: 12
Pages: 6670-5
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Publication
15494482 | J:93740
First Author: Ozaki K
Year: 2004
Journal: J Immunol
Title: Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6.
Volume: 173
Issue: 9
Pages: 5361-71
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Publication
18521959 | J:137309
First Author: Fairhurst AM
Year: 2008
Journal: Eur J Immunol
Title: Yaa autoimmune phenotypes are conferred by overexpression of TLR7.
Volume: 38
Issue: 7
Pages: 1971-8
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Publication
6886419 | J:7172
First Author: Smith HR
Year: 1983
Journal: J Immunol
Title: The effect of the X-linked immune deficiency gene (xid) upon the Y chromosome-related disease of BXSB mice.
Volume: 131
Issue: 3
Pages: 1257-62
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Publication
15048718 | J:88856
First Author: Kuroki A
Year: 2004
Journal: Eur J Immunol
Title: Enforced Bcl-2 expression in B lymphocytes induces rheumatoid factor and anti-DNA production, but the Yaa mutation promotes only anti-DNA production.
Volume: 34
Issue: 4
Pages: 1077-84
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Publication
30753473 | J:273314
First Author: Saitoh SI
Year: 2019
Journal: Int Immunol
Title: ADP-ribosylation factor-like 8b is required for the development of mouse models of systemic lupus erythematosus.
Volume: 31
Issue: 4
Pages: 225-237
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Publication
17371996 | J:145049
First Author: Rankin J
Year: 2007
Journal: J Immunol
Title: The Bxs6 locus of BXSB mice is sufficient for high-level expression of gp70 and the production of gp70 immune complexes.
Volume: 178
Issue: 7
Pages: 4395-401
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Publication
24145511 | J:207730
First Author: Giltiay NV
Year: 2013
Journal: J Exp Med
Title: Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.
Volume: 210
Issue: 12
Pages: 2773-89
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Genotype
Genotype
Symbol: Bxs6/Bxs6 Yaa/?
Background: B10.BXSB-(D13Mit3-D13Mit78) Yaa
Zygosity: cx
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Fcgr2b/Fcgr2b<+> Yaa/?
Background: involves: C57BL/6 * FVB/N * SB/Le
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Btk/Btk Yaa/?
Background: involves: BXSB/MpJ * C57BL/6JAnu * SB/Le
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Fcgrt/Fcgrt Yaa/?
Background: BXSB.129X1-Fcgrt/Dcr
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tap1/Tap1 Yaa/?
Background: BXSB.129S2(B6)-Tap1/Dcr
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cd8a/Cd8a Yaa/?
Background: BXSB.129S2(B6)-Cd8a/4Dcr
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ighm/Ighm Yaa/?
Background: BXSB.129S2(B6)-Ighm/Dcr
Zygosity: cx
Has Mutant Allele: true
•
•
•
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Publication
10435725 | J:117314
First Author: Khaled AR
Year: 1999
Journal: Autoimmunity
Title: Aberrant expression of the NF-kappaB and IkappaB proteins in B cells from viable motheaten mice.
Volume: 30
Issue: 2
Pages: 115-28
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Strain
MGI:2174228 | BXSB.129P2(B6)-H2-K1<b-tm1Bpe> H2-D1<b-tm1Bpe>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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•
•
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Strain
MGI:3804879 | B6.Cg-Nba10<NZB> Tlr7<tm1Aki> Yaa
Attribute String: congenic, spontaneous mutation, targeted mutation
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•
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•
Strain
MGI:5617629 | B6.Cg-Tlr7<tm1Flv> Yaa
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:5520950 | BXSB.129(Cg)-Il21r<tm1Wjl>/DcrJ
Attribute String: congenic, targeted mutation, mutant strain
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•
•
•
•
Strain
MGI:6093717 | BXSB.129S7(B6)-Rag1<tm1Mom>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6094190 | BXSB.129S6(B6)-Cd1d1<tm1Luc>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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•
•
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•
Strain
MGI:6094241 | BXSB.Cg-Cd8a<tm1Mak> Il15<tm1Imx>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4834593 | BXSB.129(Cg)-Il21r<tm1Wjl>/Dcr
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Strain
MGI:2174226 | BXSB.B6-Prf1<tm1Sdz>/Dcr
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5515217 | BXSB.129S2(C)-Cd1<tm1Gru>/DcrJ
Attribute String: targeted mutation, mutant strain, congenic
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•
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Publication
18606711 | J:137656
First Author: Santiago-Raber ML
Year: 2008
Journal: J Immunol
Title: Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus.
Volume: 181
Issue: 2
Pages: 1556-62
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Publication
19224760 | J:148718
First Author: Maeda K
Year: 2009
Journal: Blood
Title: Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals.
Volume: 113
Issue: 19
Pages: 4534-40
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Publication
35477763 | J:324448
First Author: Brown GJ
Year: 2022
Journal: Nature
Title: TLR7 gain-of-function genetic variation causes human lupus.
Volume: 605
Issue: 7909
Pages: 349-356
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Publication
16849473 | J:137977
First Author: Lin Q
Year: 2006
Journal: J Immunol
Title: Genetic dissection of the effects of stimulatory and inhibitory IgG Fc receptors on murine lupus.
Volume: 177
Issue: 3
Pages: 1646-54
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Publication
19164519 | J:144484
First Author: Bubier JA
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice.
Volume: 106
Issue: 5
Pages: 1518-23
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Publication
37636066 | J:339615
First Author: Wilson JJ
Year: 2023
Journal: iScience
Title: Glucose oxidation-dependent survival of activated B cells provides a putative novel therapeutic target for lupus treatment.
Volume: 26
Issue: 9
Pages: 107487
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Publication
30581114 | J:288747
First Author: Zegarra-Ruiz DF
Year: 2019
Journal: Cell Host Microbe
Title: A Diet-Sensitive Commensal Lactobacillus Strain Mediates TLR7-Dependent Systemic Autoimmunity.
Volume: 25
Issue: 1
Pages: 113-127.e6
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Genotype
Genotype
Symbol: Nba10/Nba10 Tlr7/? Yaa/?
Background: B6.Cg-Nba10 Tlr7 Yaa
Zygosity: cx
Has Mutant Allele: true
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•
•
•
•
Genotype
Genotype
Symbol: Il21r/Il21r Yaa/?
Background: BXSB.129(Cg)-Il21r/Dcr
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tlr7/? Yaa/?
Background: B6.Cg-Tlr7 Yaa
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cd8a/Cd8a Il15/Il15 Yaa/?
Background: BXSB.Cg-Cd8a Il15/Dcr
Zygosity: cx
Has Mutant Allele: true
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•
•
•
•
Genotype
Genotype
Symbol: H2-D1/H2-D1 H2-K1/H2-K1 Yaa/?
Background: BXSB.129P2(B6)-H2-K1 H2-D1/Dcr
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Cd1d1/Cd1d1 Yaa/?
Background: BXSB.129S6(B6)-Cd1d1/Dcr
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prf1/Prf1 Yaa/?
Background: BXSB.B6-Prf1/Dcr
Zygosity: cx
Has Mutant Allele: true
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•
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Publication
12974753 | J:109815
First Author: Wilber A
Year: 2003
Journal: Clin Exp Immunol
Title: Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice.
Volume: 134
Issue: 1
Pages: 46-52
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Strain
MGI:3812164 | EOD
Attribute String: recombinant inbred (RI), mutant strain, spontaneous mutation, transposition
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Strain
MGI:6353908 | EOD/ThpNkcRbrc
Attribute String: inbred strain
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Strain
MGI:5608583 | B6.Cg-Fcgr2b<tm1Ttk> Yaa
Attribute String: congenic, mutant strain, spontaneous mutation, chromosome aberration, targeted mutation
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Strain
MGI:5617613 | B6.Cg-Fcgr2b<tm1Ttk> Tlr7<tm1Flv> Yaa
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Strain
MGI:6162237 | EOD/ThpNkc
Attribute String: recombinant inbred (RI)
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Strain
MGI:5572917 | BXSB.Cg-Fcgrt<tm1Dcr> Tg(FCGRT)99Dcr/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
2599002 | J:108759
First Author: Merino R
Year: 1989
Journal: Eur J Immunol
Title: Differential effect of the autoimmune Yaa and lpr genes on the acceleration of lupus-like syndrome in MRL/MpJ mice.
Volume: 19
Issue: 11
Pages: 2131-7
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•
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Publication
762500 | J:108760
First Author: Theofilopoulos AN
Year: 1979
Journal: J Exp Med
Title: Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes.
Volume: 149
Issue: 2
Pages: 516-34
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Publication
3931946 | J:109825
First Author: Pisetsky DS
Year: 1985
Journal: Clin Immunol Immunopathol
Title: The influence of Yaa on anti-DNA responses of B6-lpr mice.
Volume: 37
Issue: 3
Pages: 369-76
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Publication
18581336 | J:137453
First Author: Anders HJ
Year: 2008
Journal: Eur J Immunol
Title: Molecular mimicry in innate immunity? The viral RNA recognition receptor TLR7 accelerates murine lupus.
Volume: 38
Issue: 7
Pages: 1795-9
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Publication
26439309 | J:253097
First Author: Elewa YH
Year: 2016
Journal: Immunology
Title: Comparative analysis of mediastinal fat-associated lymphoid cluster development and lung cellular infiltration in murine autoimmune disease models and the corresponding normal control strains.
Volume: 147
Issue: 1
Pages: 30-40
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Publication
33384689 | J:312304
 
First Author: Masum MA
Year: 2020
Journal: Front Immunol
Title: Vasculature-Associated Lymphoid Tissue: A Unique Tertiary Lymphoid Tissue Correlates With Renal Lesions in Lupus Nephritis Mouse Model.
Volume: 11
Pages: 595672
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Publication
23175700 | J:190844
First Author: Baccala R
Year: 2012
Journal: J Immunol
Title: Anti-IFN-α/β receptor antibody treatment ameliorates disease in lupus-predisposed mice.
Volume: 189
Issue: 12
Pages: 5976-84
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Publication
28267197 | J:246255
First Author: Tran NL
Year: 2017
Journal: Eur J Immunol
Title: TACI-dependent APRIL signaling maintains autoreactive B cells in a mouse model of systemic lupus erythematosus.
Volume: 47
Issue: 4
Pages: 713-723
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Publication
8597884 | J:30518
First Author: Kamada H
Year: 1995
Journal: Inflamm Res
Title: Effect of cyclophosphamide on lymphokine production in MRL/lpr.Yaa mice.
Volume: 44
Issue: 11
Pages: 491-8
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Publication
21233417 | J:169125
First Author: Kim HJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice.
Volume: 108
Issue: 5
Pages: 2010-5
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Publication
8477802 | J:4970
First Author: Suzuki H
Year: 1993
Journal: Eur J Immunol
Title: Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal.
Volume: 23
Issue: 5
Pages: 1078-82
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Publication
29190833 | J:256473
First Author: Horvei KD
Year: 2017
Journal: PLoS One
Title: Lupus nephritis progression in FcγRIIB-/-yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease.
Volume: 12
Issue: 11
Pages: e0188863
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Publication
38169466 | J:345002
First Author: Ni H
Year: 2024
Journal: Nat Commun
Title: Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice.
Volume: 15
Issue: 1
Pages: 1
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Publication
35438841 | J:336755
First Author: Chen Z
Year: 2022
Journal: Arthritis Rheumatol
Title: Interleukin-13 Receptor α1-Mediated Signaling Regulates Age-Associated/Autoimmune B Cell Expansion and Lupus Pathogenesis.
Volume: 74
Issue: 9
Pages: 1544-1555
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Publication
8601623 | J:32235
First Author: Takahashi S
Year: 1996
Journal: J Clin Invest
Title: Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice.
Volume: 97
Issue: 7
Pages: 1597-604
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Publication
14514727 | J:131473
First Author: Yoh K
Year: 2003
Journal: J Am Soc Nephrol
Title: Transgenic overexpression of GATA-3 in T lymphocytes improves autoimmune glomerulonephritis in mice with a BXSB/MpJ-Yaa genetic background.
Volume: 14
Issue: 10
Pages: 2494-502
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Publication
30936294 | J:274916
First Author: Chu T
Year: 2019
Journal: J Immunol
Title: Cutting Edge: BCAP Promotes Lupus-like Disease and TLR-Mediated Type I IFN Induction in Plasmacytoid Dendritic Cells.
Volume: 202
Issue: 9
Pages: 2529-2534
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Genotype
Genotype
Symbol: Fcgr2b/Fcgr2b<+> Yaa/?
Background: involves: 129S4/SvJae * C57BL/6 * SB/Le
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Fcgr2b/Fcgr2b Tlr7/? Yaa/?
Background: B6.Cg-Fcgr2b Tlr7 Yaa
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Fcgr2b/Fcgr2b Yaa/?
Background: B6.Cg-Fcgr2b Yaa
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
18677469 | J:140028
First Author: Zhang MC
Year: 2008
Journal: Immunogenetics
Title: Mast cell hyperplasia in the skin of Dsg4-deficient hypotrichosis mice, which are long-living mutants of lupus-prone mice.
Volume: 60
Issue: 10
Pages: 599-607
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Publication
3553324 | J:32752
First Author: Leiter EH
Year: 1987
Journal: J Immunol
Title: Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice.
Volume: 138
Issue: 10
Pages: 3224-9
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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