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Search results 401 to 500 out of 8113 for Trp53

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Type Details Score
Publication
34857912 | J:317989
First Author: Fatehullah A
Year: 2021
Journal: Nat Cell Biol
Title: A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers.
Volume: 23
Issue: 12
Pages: 1299-1313
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Publication
23644514 | J:198559
First Author: Lucas D
Year: 2013
Journal: Nat Med
Title: Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.
Volume: 19
Issue: 6
Pages: 695-703
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Publication
30778149 | J:277432
First Author: Alcantara Llaguno S
Year: 2019
Journal: Nat Neurosci
Title: Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction.
Volume: 22
Issue: 4
Pages: 545-555
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Publication
24630729 | J:211996
First Author: McFadden DG
Year: 2014
Journal: Cell
Title: Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing.
Volume: 156
Issue: 6
Pages: 1298-1311
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Publication
21665147 | J:173561
First Author: Guerra C
Year: 2011
Journal: Cancer Cell
Title: Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence.
Volume: 19
Issue: 6
Pages: 728-39
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Publication
28289141 | J:242160
First Author: Boutin AT
Year: 2017
Journal: Genes Dev
Title: Oncogenic Kras drives invasion and maintains metastases in colorectal cancer.
Volume: 31
Issue: 4
Pages: 370-382
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Publication
37169967 | J:335562
     
First Author: Ely ZA
Year: 2023
Journal: Nat Biotechnol
Title: A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
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Publication
25415051 | J:232614
 
First Author: van Bragt MP
Year: 2014
Journal: Elife
Title: RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells.
Volume: 3
Pages: e03881
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Publication
34877497 | J:318004
First Author: Zheng B
Year: 2021
Journal: iScience
Title: A new murine esophageal organoid culture method and organoid-based model of esophageal squamous cell neoplasia.
Volume: 24
Issue: 12
Pages: 103440
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Publication
36051438 | J:327869
 
First Author: Aksoy Yasar FB
Year: 2022
Journal: Front Cell Dev Biol
Title: Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma.
Volume: 10
Pages: 931387
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Publication
36604424 | J:332432
First Author: Sterling NA
Year: 2023
Journal: Nat Commun
Title: An entosis-like process induces mitotic disruption in Pals1 microcephaly pathogenesis.
Volume: 14
Issue: 1
Pages: 82
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Publication
37353528 | J:337455
First Author: Pourebrahim R
Year: 2023
Journal: Cell Death Dis
Title: Mdm2/p53 levels in bone marrow mesenchymal stromal cells are essential for maintaining the hematopoietic niche in response to DNA damage.
Volume: 14
Issue: 6
Pages: 371
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Publication
39366996 | J:355211
First Author: Flesken-Nikitin A
Year: 2024
Journal: Nat Commun
Title: Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma.
Volume: 15
Issue: 1
Pages: 8641
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Publication
27841882 | J:260936
First Author: Shingu T
Year: 2017
Journal: Nat Genet
Title: Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.
Volume: 49
Issue: 1
Pages: 75-86
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Publication
26766588 | J:231322
First Author: Serresi M
Year: 2016
Journal: Cancer Cell
Title: Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer.
Volume: 29
Issue: 1
Pages: 17-31
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Publication
28089889 | J:239378
First Author: Mollaoglu G
Year: 2017
Journal: Cancer Cell
Title: MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition.
Volume: 31
Issue: 2
Pages: 270-285
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Publication
31901081 | J:283889
First Author: Fu DJ
Year: 2020
Journal: Nat Commun
Title: Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells.
Volume: 11
Issue: 1
Pages: 84
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Publication
31968252 | J:287688
First Author: Liu Y
Year: 2020
Journal: Cell Rep
Title: Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma.
Volume: 30
Issue: 3
Pages: 771-782.e6
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Publication
32025000 | J:291017
First Author: Sethi NS
Year: 2020
Journal: Nat Genet
Title: Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model.
Volume: 52
Issue: 2
Pages: 219-230
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Publication
38703771 | J:349446
First Author: Guo T
Year: 2024
Journal: Cell Stem Cell
Title: Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor.
Volume: 31
Issue: 6
Pages: 904-920.e6
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Publication
37054704 | J:335428
First Author: Sun XL
Year: 2023
Journal: Dev Cell
Title: Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development.
Volume: 58
Issue: 9
Pages: 744-759.e11
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Publication
32976774 | J:296691
First Author: Gabitova-Cornell L
Year: 2020
Journal: Cancer Cell
Title: Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer.
Volume: 38
Issue: 4
Pages: 567-583.e11
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Publication
25961939 | J:231785
First Author: Moriarity BS
Year: 2015
Journal: Nat Genet
Title: A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.
Volume: 47
Issue: 6
Pages: 615-24
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Publication
38226620 | J:344331
 
First Author: Okato A
Year: 2024
Journal: J Clin Invest
Title: FGFR inhibition augments anti-PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression.
Volume: 134
Issue: 2
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Publication
25533335 | J:218831
First Author: Hill RM
Year: 2015
Journal: Cancer Cell
Title: Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease.
Volume: 27
Issue: 1
Pages: 72-84
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Publication
22880004 | J:189828
First Author: Dueñas M
Year: 2012
Journal: PLoS One
Title: Mouse p53-deficient cancer models as platforms for obtaining genomic predictors of human cancer clinical outcomes.
Volume: 7
Issue: 8
Pages: e42494
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Publication
24415648 | J:312169
First Author: Donehower LA
Year: 2014
Journal: Hum Mutat
Title: Insights into wild-type and mutant p53 functions provided by genetically engineered mice.
Volume: 35
Issue: 6
Pages: 715-27
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Publication
34816104 | J:316135
First Author: Su CH
Year: 2021
Journal: iScience
Title: The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia.
Volume: 24
Issue: 11
Pages: 103368
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Publication
37018402 | J:334551
First Author: Li D
Year: 2023
Journal: Sci Adv
Title: ETV4 mediates dosage-dependent prostate tumor initiation and cooperates with p53 loss to generate prostate cancer.
Volume: 9
Issue: 14
Pages: eadc9446
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Publication
11879563 | J:75240
First Author: McAllister KA
Year: 2002
Journal: Breast Cancer Res
Title: Are Trp53 rescue of Brca1 embryonic lethality and Trp53/Brca1 breast cancer association related?
Volume: 4
Issue: 2
Pages: 54-7
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Publication
20230796 | J:159230
First Author: Kim IS
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Mouse models for breast cancer metastasis.
Volume: 394
Issue: 3
Pages: 443-7
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Protein
P02340
Organism: Mus musculus/domesticus
Length: 390  
Fragment?: false
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Publication
11780111 | J:73757
First Author: Tyner SD
Year: 2002
Journal: Nature
Title: p53 mutant mice that display early ageing-associated phenotypes.
Volume: 415
Issue: 6867
Pages: 45-53
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Publication
26452271 | J:243686
First Author: Weyandt JD
Year: 2015
Journal: PLoS One
Title: Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.
Volume: 10
Issue: 10
Pages: e0140253
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Publication
29021240 | J:258794
First Author: Pourebrahim R
Year: 2017
Journal: Genes Dev
Title: Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein.
Volume: 31
Issue: 18
Pages: 1847-1857
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Publication
28318489 | J:256859
   
First Author: Foijer F
Year: 2017
Journal: Elife
Title: Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma.
Volume: 6
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Publication
15632067 | J:96007
First Author: Kang J
Year: 2005
Journal: Mol Cell Biol
Title: Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
Volume: 25
Issue: 2
Pages: 661-70
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Publication
17296936 | J:125897
First Author: Nan X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation.
Volume: 104
Issue: 8
Pages: 2709-14
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Publication
22904064 | J:199753
First Author: Neault M
Year: 2012
Journal: Nucleic Acids Res
Title: Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor.
Volume: 40
Issue: 19
Pages: 9513-21
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Publication
29358667 | J:259290
     
First Author: Zhang M
Year: 2018
Journal: Cell Death Differ
Title: Rbm24, a target of p53, is necessary for proper expression of p53 and heart development.
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Publication
12208847 | J:78820
First Author: Bender CF
Year: 2002
Journal: Genes Dev
Title: Cancer predisposition and hematopoietic failure in Rad50(S/S) mice.
Volume: 16
Issue: 17
Pages: 2237-51
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Publication
21804542 | J:241062
First Author: Sasaki M
Year: 2011
Journal: Nat Med
Title: Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.
Volume: 17
Issue: 8
Pages: 944-51
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Publication
24051492 | J:217260
 
First Author: Miki T
Year: 2013
Journal: Nat Commun
Title: p53 regulates Period2 expression and the circadian clock.
Volume: 4
Pages: 2444
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Publication
15668238 | J:98749
First Author: Linggi MS
Year: 2005
Journal: J Biol Chem
Title: Neurotrophin receptor interacting factor (NRIF) is an essential mediator of apoptotic signaling by the p75 neurotrophin receptor.
Volume: 280
Issue: 14
Pages: 13801-8
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Publication
17694067 | J:125183
First Author: Zhang L
Year: 2007
Journal: Nat Med
Title: The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.
Volume: 13
Issue: 9
Pages: 1060-9
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Publication
28738408 | J:250116
First Author: Mackenzie KJ
Year: 2017
Journal: Nature
Title: cGAS surveillance of micronuclei links genome instability to innate immunity.
Volume: 548
Issue: 7668
Pages: 461-465
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Publication
24115439 | J:202812
First Author: Vannier JB
Year: 2013
Journal: Science
Title: RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication.
Volume: 342
Issue: 6155
Pages: 239-42
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Publication
29073078 | J:256932
First Author: Yang HJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Ninjurin 1 has two opposing functions in tumorigenesis in a p53-dependent manner.
Volume: 114
Issue: 43
Pages: 11500-11505
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Publication
32628936 | J:290235
     
First Author: Archambault D
Year: 2020
Journal: Dev Biol
Title: Protein phosphatase 1 regulatory subunit 35 is required for ciliogenesis, notochord morphogenesis, and cell-cycle progression during murine development.
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Publication
22342750 | J:182280
First Author: Chen D
Year: 2012
Journal: Curr Biol
Title: Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis.
Volume: 22
Issue: 5
Pages: 420-5
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Publication
18202109 | J:132597
First Author: De Lisle RC
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Effects of Muclin (Dmbt1) deficiency on the gastrointestinal system.
Volume: 294
Issue: 3
Pages: G717-27
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Publication
14744934 | J:88090
First Author: Chen CM
Year: 2004
Journal: Genes Dev
Title: Ovca1 regulates cell proliferation, embryonic development, and tumorigenesis.
Volume: 18
Issue: 3
Pages: 320-32
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Publication
20375365 | J:167880
First Author: Haldar SM
Year: 2010
Journal: Sci Transl Med
Title: Klf15 deficiency is a molecular link between heart failure and aortic aneurysm formation.
Volume: 2
Issue: 26
Pages: 26ra26
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Publication
18775323 | J:138774
First Author: Li G
Year: 2008
Journal: Mol Cell
Title: Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination.
Volume: 31
Issue: 5
Pages: 631-40
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Publication
21857671 | J:176962
First Author: Peuscher MH
Year: 2011
Journal: Nat Cell Biol
Title: DNA-damage response and repair activities at uncapped telomeres depend on RNF8.
Volume: 13
Issue: 9
Pages: 1139-45
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Publication
29262616 | J:272648
First Author: Aryal NK
Year: 2017
Journal: Oncotarget
Title: Loss of digestive organ expansion factor (Diexf) reveals an essential role during murine embryonic development that is independent of p53.
Volume: 8
Issue: 61
Pages: 103996-104006
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Publication
20975832 | J:166226
First Author: Lynch CJ
Year: 2010
Journal: PLoS One
Title: SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.
Volume: 5
Issue: 10
Pages: e13502
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Publication
16222716 | J:102855
First Author: Jerome-Majewska LA
Year: 2005
Journal: Dev Dyn
Title: Tbx3, the ulnar-mammary syndrome gene, and Tbx2 interact in mammary gland development through a p19Arf/p53-independent pathway.
Volume: 234
Issue: 4
Pages: 922-33
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Publication
26446488 | J:227643
 
First Author: Liu XS
Year: 2015
Journal: Nat Commun
Title: LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.
Volume: 6
Pages: 8325
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Publication
17906694 | J:135509
First Author: Iwakuma T
Year: 2008
Journal: Oncogene
Title: Mtbp haploinsufficiency in mice increases tumor metastasis.
Volume: 27
Issue: 13
Pages: 1813-20
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Publication
24652652 | J:210814
First Author: Polato F
Year: 2014
Journal: J Natl Cancer Inst
Title: DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected].
Volume: 106
Issue: 4
Pages: dju053
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Publication
20339076 | J:158884
First Author: Sfeir A
Year: 2010
Journal: Science
Title: Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal.
Volume: 327
Issue: 5973
Pages: 1657-61
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Publication
15282321 | J:92269
First Author: Saunders DN
Year: 2004
Journal: Mol Cell Biol
Title: Edd, the murine hyperplastic disc gene, is essential for yolk sac vascularization and chorioallantoic fusion.
Volume: 24
Issue: 16
Pages: 7225-34
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Publication
28839193 | J:254597
First Author: Bhargava S
Year: 2017
Journal: Sci Rep
Title: The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.
Volume: 7
Issue: 1
Pages: 9322
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Publication
19118006 | J:143030
First Author: Cano CE
Year: 2009
Journal: Cancer Res
Title: Tumor protein 53-induced nuclear protein 1 is a major mediator of p53 antioxidant function.
Volume: 69
Issue: 1
Pages: 219-26
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Publication
11726500 | J:73034
First Author: Sotillo R
Year: 2001
Journal: EMBO J
Title: Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.
Volume: 20
Issue: 23
Pages: 6637-47
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Publication
16728594 | J:109676
First Author: Matoba S
Year: 2006
Journal: Science
Title: p53 regulates mitochondrial respiration.
Volume: 312
Issue: 5780
Pages: 1650-3
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Publication
24647794 | J:215071
First Author: Leblond F
Year: 2014
Journal: PLoS One
Title: The anti-hypercholesterolemic effect of low p53 expression protects vascular endothelial function in mice.
Volume: 9
Issue: 3
Pages: e92394
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Publication
12752260 | J:82965
First Author: Lam MY
Year: 2003
Journal: APMIS
Title: Genetic control of susceptibility to spontaneous testicular germ cell tumors in mice.
Volume: 111
Issue: 1
Pages: 184-90; discussion 191
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Publication
11914272 | J:75569
First Author: Pani L
Year: 2002
Journal: Genes Dev
Title: Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis.
Volume: 16
Issue: 6
Pages: 676-80
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Publication
23649518 | J:208963
First Author: Deshpande SD
Year: 2013
Journal: Diabetes
Title: Transforming growth factor-β-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathy.
Volume: 62
Issue: 9
Pages: 3151-62
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Publication
32304665 | J:290208
First Author: Chung KM
Year: 2020
Journal: Cell
Title: Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma.
Volume: 181
Issue: 4
Pages: 832-847.e18
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Publication
27354067 | J:236161
First Author: Wang Y
Year: 2016
Journal: Mol Cell Biol
Title: Follicle Depletion Provides a Permissive Environment for Ovarian Carcinogenesis.
Volume: 36
Issue: 18
Pages: 2418-30
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Publication
18641651 | J:139244
First Author: McGowan KA
Year: 2008
Journal: Nat Genet
Title: Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects.
Volume: 40
Issue: 8
Pages: 963-70
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Publication
22133876 | J:184414
First Author: Schoppy DW
Year: 2012
Journal: J Clin Invest
Title: Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR.
Volume: 122
Issue: 1
Pages: 241-52
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Publication
14985341 | J:124263
First Author: Yahagi N
Year: 2004
Journal: J Biol Chem
Title: p53 involvement in the pathogenesis of fatty liver disease.
Volume: 279
Issue: 20
Pages: 20571-5
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Publication
16951207 | J:112412
First Author: Ablamunits V
Year: 2006
Journal: Cancer Res
Title: Susceptibility to induced and spontaneous carcinogenesis is increased in fatless A-ZIP/F-1 but not in obese ob/ob mice.
Volume: 66
Issue: 17
Pages: 8897-902
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Publication
12734185 | J:120652
First Author: Yahagi N
Year: 2003
Journal: J Biol Chem
Title: p53 Activation in adipocytes of obese mice.
Volume: 278
Issue: 28
Pages: 25395-400
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Publication
34857760 | J:317949
First Author: Lacroix M
Year: 2021
Journal: Nat Commun
Title: The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes.
Volume: 12
Issue: 1
Pages: 7037
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Publication
26074075 | J:228688
First Author: Qiang L
Year: 2015
Journal: Cell Rep
Title: Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions.
Volume: 11
Issue: 11
Pages: 1797-808
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Publication
9294187 | J:42974
First Author: Fazeli A
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas.
Volume: 94
Issue: 19
Pages: 10199-204
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Publication
33753942 | J:305794
First Author: Raundhal M
Year: 2021
Journal: Nat Immunol
Title: Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias.
Volume: 22
Issue: 4
Pages: 520-529
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Publication
38167344 | J:344081
First Author: Wang J
Year: 2024
Journal: Nat Commun
Title: p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome.
Volume: 15
Issue: 1
Pages: 137
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Publication
11323676 | J:68981
First Author: Johnson L
Year: 2001
Journal: Nature
Title: Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.
Volume: 410
Issue: 6832
Pages: 1111-6
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Publication
9453487 | J:46025
First Author: Smits R
Year: 1998
Journal: Gastroenterology
Title: Apc1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts.
Volume: 114
Issue: 2
Pages: 275-83
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Publication
21362628 | J:172257
First Author: Oghamian S
Year: 2011
Journal: Carcinogenesis
Title: Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice.
Volume: 32
Issue: 6
Pages: 829-35
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Publication
18723878 | J:139675
First Author: Halberg RB
Year: 2008
Journal: Genetics
Title: The pleiotropic phenotype of Apc mutations in the mouse: allele specificity and effects of the genetic background.
Volume: 180
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