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Search results 401 to 500 out of 766 for Vav1

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Type Details Score
Protein Coding Gene
MGI:1339656 | Pak3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q61036
Organism: Mus musculus/domesticus
Length: 559  
Fragment?: false
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Publication
33586242 | J:306148
First Author: Chen Y
Year: 2021
Journal: Cell Prolif
Title: Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
Volume: 54
Issue: 3
Pages: e12972
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Allele
Tg(Vav1-JAK2*V617F)AZjz | MGI:5441310
Name: transgene insertion A, Zhizhuang Joe Zhao
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
31395598 | J:278804
First Author: Hsu YC
Year: 2019
Journal: Blood Adv
Title: Phf6-null hematopoietic stem cells have enhanced self-renewal capacity and oncogenic potentials.
Volume: 3
Issue: 15
Pages: 2355-2367
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Publication
29567783 | J:320639
First Author: Kardosova M
Year: 2018
Journal: Haematologica
Title: C/EBPγ is dispensable for steady-state and emergency granulopoiesis.
Volume: 103
Issue: 8
Pages: e331-e335
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Publication
31175292 | J:283551
First Author: de Araujo ED
Year: 2019
Journal: Nat Commun
Title: Structural and functional consequences of the STAT5BN642H driver mutation.
Volume: 10
Issue: 1
Pages: 2517
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Allele
Vav1<m1Btlr> | MGI:6199670
Name: vav 1 oncogene; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6199671 | C57BL/6J-Vav1<m1Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Allele
Vav1<m2Btlr> | MGI:6199674
Name: vav 1 oncogene; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6199675 | C57BL/6J-Vav1<m2Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Allele
Vav1<M3Btlr> | MGI:6285507
Name: vav 1 oncogene; mutation 3, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6285508 | C57BL/6J-Vav1<M3Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Allele
Vav1<M4Btlr> | MGI:6285514
Name: vav 1 oncogene; mutation 4, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6285515 | C57BL/6J-Vav1<M4Btlr>
Attribute String: chemically induced mutation, mutant strain, coisogenic
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Allele
Vav1<M5Btlr> | MGI:6285528
Name: vav 1 oncogene; mutation 5, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6285534 | C57BL/6J-Vav1<M5Btlr>
Attribute String: mutant strain, coisogenic, chemically induced mutation
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Allele
Tg(VAV1-EGFP)#Forsb | MGI:6359439
Name: transgene insertion, E Camilla Forsberg
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Vav1-Mpl)AAmol | MGI:7387059
Name: transgene insertion A, Alison Moliterno
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Vav1-Mpl)EAmol | MGI:7387062
Name: transgene insertion E, Alison Moliterno
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(VAV1-EGFP)1Forsb | MGI:7593595
Name: transgene insertion 1, E Camilla Forsberg
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Phf6/Phf6 Tg(Vav1-cre)#Cgp/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Phf6/? Tg(Vav1-cre)#Cgp/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Vav1/Vav1
Background: C57BL/6J-Vav1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Vav1/Vav1
Background: C57BL/6J-Vav1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Vav1/Vav1
Background: C57BL/6J-Vav1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Vav1/Vav1
Background: C57BL/6J-Vav1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Vav1/Vav1
Background: C57BL/6J-Vav1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rasa3/Rasa3 Tg(Vav1-cre)1Cgp/?
Background: involves: 129S1/SvImJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mirc27/Mirc27 Tg(Vav1-cre)#Cgp/?
Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mirc30/Mirc30 Tg(Vav1-cre)#Cgp/?
Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj
Zygosity: cn
Has Mutant Allele: true
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Protein Coding Gene
MGI:1339984 | Pak2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96756 | Lck
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8CIN4
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: false
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Protein
P06240
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: false
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Publication
25810396 | -
First Author: Ainsua-Enrich E
Year: 2015
Journal: J Immunol
Title: The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival.
Volume: 194
Issue: 9
Pages: 4309-18
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Publication
18336269 | -
First Author: Hatani T
Year: 2008
Journal: Curr Med Chem
Title: Adaptor protein 3BP2 and cherubism.
Volume: 15
Issue: 6
Pages: 549-54
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Publication
22153076 | J:178917
First Author: Levaot N
Year: 2011
Journal: Cell
Title: Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism.
Volume: 147
Issue: 6
Pages: 1324-39
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Publication
15751964 | -
First Author: Qu X
Year: 2005
Journal: Biochemistry
Title: Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor.
Volume: 44
Issue: 10
Pages: 3891-8
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Protein Domain
IPR035879 | VAV1_SH2
Type: Domain
Description: This entry represents the SH2 domain of VAV1 from vertebrates.VAV1 (also known as proto-oncogene vav) is expressed predominantly in the hematopoietic system and it plays an important role in the development and activation of B and T cells [, , ]. It is activated by tyrosine phosphorylation to function as a guanine nucleotide exchange factor (GEF) for Rho GTPases following cell surface receptor activation, triggering various effects such as cytoskeletal reorganization, transcription regulation, cell cycle progression, and calcium mobilization [, ]. It also serves as a scaffold protein and has been shown to interact with Ku70, Socs1, Janus kinase 2, SIAH2, S100B, Abl gene, ZAP-70, SLP76, and Syk, among others []. The VAV protein family members are multiple domain proteins, including Vav from flies and VAV1/2/3 from mammals. VAV1 predominates in hematopoietic cells, whereas VAV2 and VAV3 are more broadly expressed. They have a calponin homology (CH) domain, an acidic domain (AC), a Dbl homology (DH) domain, a pleckstrin homology (PH) domain, a cysteine-rich (CR) domain containing a zinc finger, and a complex region with SH2 and SH3 domains. Therefore they may participate in the activity of several pathways [, ]. They are signal transducer proteins that couple tyrosine kinase signals with the activation of the Rho/Rac GTPases, [, , ].
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Publication
18048646 | J:131328
First Author: Daria D
Year: 2008
Journal: Blood
Title: The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress.
Volume: 111
Issue: 4
Pages: 1894-902
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Publication
17277115 | J:143995
First Author: Dzhagalov I
Year: 2007
Journal: J Immunol
Title: Regulation of CD8+ T lymphocyte effector function and macrophage inflammatory cytokine production by retinoic acid receptor gamma.
Volume: 178
Issue: 4
Pages: 2113-21
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Publication
37813816 | J:358134
First Author: Soma S
Year: 2024
Journal: Stem Cells
Title: O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation.
Volume: 42
Issue: 1
Pages: 55-63
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Strain
MGI:5496048 | B6.Cg-Bclaf1<tm1Lfmp> Tg(Vav1-cre)1Cgp/Ieg
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
32533074 | J:293844
First Author: Leonards K
Year: 2020
Journal: Nat Commun
Title: Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia.
Volume: 11
Issue: 1
Pages: 2807
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Publication
22611193 | J:184747
First Author: Taniguchi Ishikawa E
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells.
Volume: 109
Issue: 23
Pages: 9071-6
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Allele
Tg(VAV1-cre)1Graf | MGI:3765313
Name: transgene insertion 1, Thomas Graf
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
21536859 | J:174808
First Author: Thoms JA
Year: 2011
Journal: Blood
Title: ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.
Volume: 117
Issue: 26
Pages: 7079-89
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Publication
18334677 | J:135993
First Author: Xing S
Year: 2008
Journal: Blood
Title: Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice.
Volume: 111
Issue: 10
Pages: 5109-17
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Publication
22019628 | J:191404
First Author: Majumder A
Year: 2012
Journal: Exp Hematol
Title: A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth.
Volume: 40
Issue: 1
Pages: 22-34
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Publication
31709318 | J:285383
First Author: Sano S
Year: 2019
Journal: JACC Basic Transl Sci
Title: JAK2 V617F -Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure.
Volume: 4
Issue: 6
Pages: 684-697
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Publication
32294178 | J:301286
First Author: Matsuura S
Year: 2020
Journal: Blood
Title: Adhesion to fibronectin via α5β1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis.
Volume: 135
Issue: 25
Pages: 2286-2291
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Publication
22796437 | J:188525
First Author: Kirabo A
Year: 2012
Journal: Am J Pathol
Title: The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis.
Volume: 181
Issue: 3
Pages: 858-65
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Publication
24391943 | J:209831
First Author: Jin X
Year: 2013
Journal: PLoS One
Title: Generation of a new congenic mouse strain with enhanced chymase expression in mast cells.
Volume: 8
Issue: 12
Pages: e84340
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Allele
Tg(Vav1-Asxl1*Y588X)#Fcy | MGI:6315194
Name: transgene insertion, Feng-Chun Yang
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
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Allele
Vav1<tm1.1(Myo1f)Tpal> | MGI:7431424
Name: vav 1 oncogene; targeted mutation 1.1, Teresa Palomero
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Strain
MGI:7387063 | B6.Cg-Tg(Vav1-Mpl)AAmol/J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:7387064 | B6.Cg-Tg(Vav1-Mpl)EAmol/J
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:6348208 | C57BL/6-Tg(VAV1-EGFP)1Forsb/Mmucd
Attribute String: transgenic, coisogenic, mutant strain
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Genotype
Genotype
Symbol: Tg(Vav1-JAK2*V617F)AZjz/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bcr/Bcr Tg(Vav1-cre)#Cgp/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bcr/Bcr<+> Tg(Vav1-cre)#Cgp/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Otud5/Otud5 Tg(Vav1-cre)#Cgp/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Srf/Srf Tg(Vav1-cre)#Cgp/?
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rpl22l1/Rpl22l1 Tg(Vav1-cre)#Cgp/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Protein
D3Z107
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: true
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Publication
26919541 | -
First Author: Liu S
Year: 2016
Journal: FEBS Lett
Title: Structural basis for a novel interaction between TXNIP and Vav2.
Volume: 590
Issue: 6
Pages: 857-65
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Publication
28214347 | -
First Author: Ulc A
Year: 2017
Journal: Biol Chem
Title: Involvement of the guanine nucleotide exchange factor Vav3 in central nervous system development and plasticity.
Volume: 398
Issue: 5-6
Pages: 663-675
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Protein Domain
IPR035880 | VAV2_SH2
Type: Domain
Description: This entry represents the SH2 domain of VAV2, which is a member of the VAV family. The SH2 domain of VAV2 has been shown to interact with PPxY motifs of TXNIP (thioredoxin-interacting protein) []. The VAV protein family members are multiple domain proteins, including Vav from flies and VAV1/2/3 from mammals. VAV1 predominates in hematopoietic cells, whereas VAV2 and VAV3 are more broadly expressed. They have a calponin homology (CH) domain, an acidic domain (AC), a Dbl homology (DH) domain, a pleckstrin homology (PH) domain, a cysteine-rich (CR) domain containing a zinc finger, and a complex region with SH2 and SH3 domains. Therefore they may participate in the activity of several pathways [, ]. They are signal transducer proteins that couple tyrosine kinase signals with the activation of the Rho/Rac GTPases, [, , ].
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Protein Domain
IPR035881 | VAV3_SH2
Type: Domain
Description: This entry represents the SH2 domain of VAV3, which belongs to the VAV family. VAV3 is involved in the regulation of osteoclast function []and in central nervous system development and plasticity [].The VAV protein family members are multiple domain proteins, including Vav from flies and VAV1/2/3 from mammals. VAV1 predominates in hematopoietic cells, whereas VAV2 and VAV3 are more broadly expressed. They have a calponin homology (CH) domain, an acidic domain (AC), a Dbl homology (DH) domain, a pleckstrin homology (PH) domain, a cysteine-rich (CR) domain containing a zinc finger, and a complex region with SH2 and SH3 domains. Therefore they may participate in the activity of several pathways [, ]. They are signal transducer proteins that couple tyrosine kinase signals with the activation of the Rho/Rac GTPases, [, , ].
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Protein Domain
IPR035847 | SH3BP2_SH2
Type: Domain
Description: The adaptor protein 3BP2/SH3BP2 is a cytoplasmic adaptor that contributes to the regulation of immune responses []. The protein-tyrosine kinase Syk phosphorylates 3BP2 which results in the activation of Rac1 through the interaction with the SH2 domain of Vav1 and induces the binding to the SH2 domain of the upstream protein-tyrosine kinase Lyn and enhances its kinase activity []. 3BP2 has a positive regulatory role in IgE-mediated mast cell activation []. In lymphocytes, engagement of T cell or B cell receptors triggers tyrosine phosphorylation of 3BP2 []. 3BP2 is required for the proliferation of B cells and B cell receptor signaling. Mutations in the 3BP2 gene are responsible for cherubism resulting in excessive bone resorption in the jaw [].This entry represents the SH2 domain of SH3BP2.
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Protein Domain
IPR035848 | SH3BP2
Type: Family
Description: The adaptor protein 3BP2/SH3BP2 is a cytoplasmic adaptor that contributes to the regulation of immune responses []. The protein-tyrosine kinase Syk phosphorylates 3BP2 which results in the activation of Rac1 through the interaction with the SH2 domain of Vav1 and induces the binding to the SH2 domain of the upstream protein-tyrosine kinase Lyn and enhances its kinase activity []. 3BP2 has a positive regulatory role in IgE-mediated mast cell activation []. In lymphocytes, engagement of T cell or B cell receptors triggers tyrosine phosphorylation of 3BP2 []. 3BP2 is required for the proliferation of B cells and B cell receptor signaling. Mutations in the 3BP2 gene are responsible for cherubism resulting in excessive bone resorption in the jaw [].
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Publication
24584089 | J:209882
First Author: Roncagalli R
Year: 2014
Journal: Nat Immunol
Title: Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.
Volume: 15
Issue: 4
Pages: 384-392
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Publication
17119112 | J:143161
First Author: Dorn T
Year: 2007
Journal: Blood
Title: RhoH is important for positive thymocyte selection and T-cell receptor signaling.
Volume: 109
Issue: 6
Pages: 2346-55
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Publication
19435813 | J:205248
First Author: Brantley-Sieders DM
Year: 2009
Journal: Mol Cancer Res
Title: Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo.
Volume: 7
Issue: 5
Pages: 615-23
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Publication
33837181 | J:316974
First Author: Jia W
Year: 2021
Journal: Nat Commun
Title: Indispensable role of Galectin-3 in promoting quiescence of hematopoietic stem cells.
Volume: 12
Issue: 1
Pages: 2118
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Publication
23377202 | J:193617
First Author: Guy CS
Year: 2013
Journal: Nat Immunol
Title: Distinct TCR signaling pathways drive proliferation and cytokine production in T cells.
Volume: 14
Issue: 3
Pages: 262-70
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Publication
30291029 | J:277012
First Author: Proto JD
Year: 2018
Journal: Immunity
Title: Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution.
Volume: 49
Issue: 4
Pages: 666-677.e6
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Publication
34471108 | J:310403
First Author: Hoefig KP
Year: 2021
Journal: Nat Commun
Title: Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
Volume: 12
Issue: 1
Pages: 5208
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Publication
16782030 | J:113367
First Author: Gomez TS
Year: 2006
Journal: Immunity
Title: HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
Volume: 24
Issue: 6
Pages: 741-52
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Publication
34622148 | J:314365
First Author: Titelbaum M
Year: 2021
Journal: iScience
Title: Ezh2 harnesses the intranuclear actin cytoskeleton to remodel chromatin in differentiating Th cells.
Volume: 24
Issue: 10
Pages: 103093
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Publication
16487932 | J:106161
First Author: Hardin AO
Year: 2006
Journal: Biochem Biophys Res Commun
Title: SHP-1 inhibits LPS-mediated TNF and iNOS production in murine macrophages.
Volume: 342
Issue: 2
Pages: 547-55
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Publication
31644919 | J:300701
First Author: Laufer JM
Year: 2019
Journal: Cell Rep
Title: Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation.
Volume: 29
Issue: 4
Pages: 995-1009.e6
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Publication
22345706 | J:183785
First Author: Park CS
Year: 2012
Journal: J Leukoc Biol
Title: Kruppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen.
Volume: 91
Issue: 5
Pages: 739-50
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Publication
32705746 | J:320883
First Author: Hutter K
Year: 2021
Journal: FEBS J
Title: Differential roles of miR-15a/16-1 and miR-497/195 clusters in immune cell development and homeostasis.
Volume: 288
Issue: 5
Pages: 1533-1545
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Publication
29498802 | J:277367
First Author: Tuzlak S
Year: 2018
Journal: FEBS J
Title: Differential effects of Vav-promoter-driven overexpression of BCLX and BFL1 on lymphocyte survival and B cell lymphomagenesis.
Volume: 285
Issue: 8
Pages: 1403-1418
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Publication
23502962 | J:197987
First Author: Chow A
Year: 2013
Journal: Nat Med
Title: CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress.
Volume: 19
Issue: 4
Pages: 429-36
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Publication
25299771 | J:254584
 
First Author: Herold MJ
Year: 2014
Journal: Cell Death Dis
Title: Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice.
Volume: 5
Pages: e1446
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Strain
MGI:6454987 | B6.Cg-Tg(VAV1-cre)1Graf/MdfJ
Attribute String: transgenic, mutant strain, congenic
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Publication
32555370 | J:299288
First Author: Grahn THM
Year: 2020
Journal: Leukemia
Title: S100A6 is a critical regulator of hematopoietic stem cells.
Volume: 34
Issue: 12
Pages: 3323-3337
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Publication
33158956 | J:300740
First Author: Luo L
Year: 2020
Journal: J Immunol
Title: Kras-Deficient T Cells Attenuate Graft-versus-Host Disease but Retain Graft-versus-Leukemia Activity.
Volume: 205
Issue: 12
Pages: 3480-3490
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Publication
24951423 | J:214527
First Author: Lamrani L
Year: 2014
Journal: Blood
Title: Hemostatic disorders in a JAK2V617F-driven mouse model of myeloproliferative neoplasm.
Volume: 124
Issue: 7
Pages: 1136-45
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Publication
33262527 | J:337217
First Author: Liu MH
Year: 2021
Journal: Leukemia
Title: FAM122A is required for hematopoietic stem cell function.
Volume: 35
Issue: 7
Pages: 2130-2134
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Genotype
Genotype
Symbol: Tg(Vav1-Asxl1*Y588X)#Fcy/?
Background: C57BL/6-Tg(Vav1-Asxl1*Y588X)#Fcy
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nbn/Nbn Tg(VAV1-cre)1Graf/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(VAV1-cre)1Graf/?
Background: involves: 129 * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(VAV1-cre)1Graf/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(VAV1-cre)1Graf/?
Background: involves: 129P2/OlaHsd
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(VAV1-cre)1Graf/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Protein Coding Gene
MGI:95602 | Fyn
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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