Type |
Details |
Score |
Publication |
First Author: |
Wang M |
Year: |
2017 |
Journal: |
Mol Cell Proteomics |
Title: |
The Glial Cell-Derived Neurotrophic Factor (GDNF)-responsive Phosphoprotein Landscape Identifies Raptor Phosphorylation Required for Spermatogonial Progenitor Cell Proliferation. |
Volume: |
16 |
Issue: |
6 |
Pages: |
982-997 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deng D |
Year: |
2024 |
Journal: |
Bone Res |
Title: |
Osteoclasts control endochondral ossification via regulating acetyl-CoA availability. |
Volume: |
12 |
Issue: |
1 |
Pages: |
49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ou YH |
Year: |
2011 |
Journal: |
Mol Cell |
Title: |
TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation. |
Volume: |
41 |
Issue: |
4 |
Pages: |
458-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kohnke S |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence. |
Volume: |
36 |
Issue: |
2 |
Pages: |
109362 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun F |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity. |
Volume: |
30 |
Issue: |
6 |
Pages: |
1835-1847.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hertzler-Schaefer K |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
Pten loss induces autocrine FGF signaling to promote skin tumorigenesis. |
Volume: |
6 |
Issue: |
5 |
Pages: |
818-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang M |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. |
Volume: |
7 |
|
Pages: |
12730 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hung CM |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease. |
Volume: |
8 |
Issue: |
1 |
Pages: |
256-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang SC |
Year: |
2016 |
Journal: |
Immunity |
Title: |
Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation. |
Volume: |
45 |
Issue: |
4 |
Pages: |
817-830 |
|
•
•
•
•
•
|
Publication |
First Author: |
Harada Y |
Year: |
2022 |
Journal: |
iScience |
Title: |
Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes. |
Volume: |
25 |
Issue: |
4 |
Pages: |
104021 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cullen ER |
Year: |
2024 |
Journal: |
Elife |
Title: |
Hyperactivity of mTORC1- and mTORC2-dependent signaling mediates epilepsy downstream of somatic PTEN loss. |
Volume: |
12 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Moloughney JG |
Year: |
2016 |
Journal: |
Mol Cell |
Title: |
mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1. |
Volume: |
63 |
Issue: |
5 |
Pages: |
811-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2023 |
Journal: |
iScience |
Title: |
Natural γδT17 cell development and functional acquisition is governed by the mTORC2-c-Maf-controlled mitochondrial fission pathway. |
Volume: |
26 |
Issue: |
5 |
Pages: |
106630 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1333
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kunz J |
Year: |
1993 |
Journal: |
Cell |
Title: |
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. |
Volume: |
73 |
Issue: |
3 |
Pages: |
585-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xia H |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Evasion of Type I Interferon by SARS-CoV-2. |
Volume: |
33 |
Issue: |
1 |
Pages: |
108234 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yau WW |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
Thyroid hormone (T3) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy. |
Volume: |
15 |
Issue: |
1 |
Pages: |
131-150 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee TY |
Year: |
2021 |
Journal: |
Autophagy |
Title: |
Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism. |
Volume: |
17 |
Issue: |
12 |
Pages: |
4141-4158 |
|
•
•
•
•
•
|
Publication |
First Author: |
Malik TH |
Year: |
2001 |
Journal: |
EMBO J |
Title: |
Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1. |
Volume: |
20 |
Issue: |
7 |
Pages: |
1715-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karmaus PWF |
Year: |
2019 |
Journal: |
Nature |
Title: |
Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity. |
Volume: |
565 |
Issue: |
7737 |
Pages: |
101-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magee JA |
Year: |
2012 |
Journal: |
Cell Stem Cell |
Title: |
Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression. |
Volume: |
11 |
Issue: |
3 |
Pages: |
415-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ai D |
Year: |
2014 |
Journal: |
Circ Res |
Title: |
Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis. |
Volume: |
114 |
Issue: |
10 |
Pages: |
1576-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerlach BD |
Year: |
2021 |
Journal: |
Cell Metab |
Title: |
Efferocytosis induces macrophage proliferation to help resolve tissue injury. |
Volume: |
33 |
Issue: |
12 |
Pages: |
2445-2463.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Everts B |
Year: |
2014 |
Journal: |
Nat Immunol |
Title: |
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKÉ› supports the anabolic demands of dendritic cell activation. |
Volume: |
15 |
Issue: |
4 |
Pages: |
323-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Opejin A |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
A Two-Step Process of Effector Programming Governs CD4(+) T Cell Fate Determination Induced by Antigenic Activation in the Steady State. |
Volume: |
33 |
Issue: |
8 |
Pages: |
108424 |
|
•
•
•
•
•
|
Publication |
First Author: |
Do MH |
Year: |
2023 |
Journal: |
Immunity |
Title: |
Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis. |
Volume: |
56 |
Issue: |
11 |
Pages: |
2555-2569.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang S |
Year: |
2023 |
Journal: |
J Clin Invest |
Title: |
The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells. |
Volume: |
133 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kogot-Levin A |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors. |
Volume: |
32 |
Issue: |
4 |
Pages: |
107954 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bohin N |
Year: |
2020 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury. |
Volume: |
10 |
Issue: |
4 |
Pages: |
797-810 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang L |
Year: |
2017 |
Journal: |
PLoS Biol |
Title: |
Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin. |
Volume: |
15 |
Issue: |
8 |
Pages: |
e2001750 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JH |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
SREBP-1a-stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1. |
Volume: |
115 |
Issue: |
52 |
Pages: |
E12228-E12234 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang C |
Year: |
2016 |
Journal: |
Liver Int |
Title: |
Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade. |
Volume: |
36 |
Issue: |
8 |
Pages: |
1176-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Canaud G |
Year: |
2013 |
Journal: |
Nat Med |
Title: |
AKT2 is essential to maintain podocyte viability and function during chronic kidney disease. |
Volume: |
19 |
Issue: |
10 |
Pages: |
1288-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bridges CR |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors. |
Volume: |
7 |
Issue: |
1 |
Pages: |
391 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gosis BS |
Year: |
2022 |
Journal: |
Science |
Title: |
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1. |
Volume: |
376 |
Issue: |
6590 |
Pages: |
eabf8271 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wan M |
Year: |
2011 |
Journal: |
Cell Metab |
Title: |
Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c. |
Volume: |
14 |
Issue: |
4 |
Pages: |
516-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2014 |
Journal: |
Curr Biol |
Title: |
Somatic cells initiate primordial follicle activation and govern the development of dormant oocytes in mice. |
Volume: |
24 |
Issue: |
21 |
Pages: |
2501-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van de Velde LA |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions. |
Volume: |
292 |
Issue: |
1 |
Pages: |
15-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2023 |
Journal: |
Cell Metab |
Title: |
Dietary fructose-mediated adipocyte metabolism drives antitumor CD8(+) TÂ cell responses. |
Volume: |
35 |
Issue: |
12 |
Pages: |
2107-2118.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yin N |
Year: |
2022 |
Journal: |
J Clin Invest |
Title: |
SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation. |
Volume: |
132 |
Issue: |
20 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wang C |
Year: |
2015 |
Journal: |
Hepatology |
Title: |
4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice. |
Volume: |
61 |
Issue: |
1 |
Pages: |
200-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng P |
Year: |
2021 |
Journal: |
Theranostics |
Title: |
The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis. |
Volume: |
11 |
Issue: |
19 |
Pages: |
9503-9518 |
|
•
•
•
•
•
|
Publication |
First Author: |
Castets P |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4. |
Volume: |
10 |
Issue: |
1 |
Pages: |
3187 |
|
•
•
•
•
•
|
Publication |
First Author: |
Covarrubias AJ |
Year: |
2016 |
Journal: |
Elife |
Title: |
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kang YJ |
Year: |
2011 |
Journal: |
Cell Death Differ |
Title: |
The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis. |
Volume: |
18 |
Issue: |
1 |
Pages: |
133-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Akgül S |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma. |
Volume: |
24 |
Issue: |
2 |
Pages: |
463-478.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Venkatesh A |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. |
Volume: |
125 |
Issue: |
4 |
Pages: |
1446-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nobs SP |
Year: |
2015 |
Journal: |
Immunity |
Title: |
PI3-Kinase-γ Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development. |
Volume: |
43 |
Issue: |
4 |
Pages: |
674-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosenlehner T |
Year: |
2024 |
Journal: |
Sci Signal |
Title: |
Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells. |
Volume: |
17 |
Issue: |
859 |
Pages: |
eadi8753 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
525
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
392
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3658
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wolff NC |
Year: |
2011 |
Journal: |
Mol Cell Biol |
Title: |
Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia. |
Volume: |
31 |
Issue: |
9 |
Pages: |
1870-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng D |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). |
Volume: |
10 |
Issue: |
6 |
Pages: |
e0126240 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yi W |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity. |
Volume: |
8 |
Issue: |
1 |
Pages: |
254 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huynh H |
Year: |
2018 |
Journal: |
Commun Biol |
Title: |
mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1. |
Volume: |
1 |
|
Pages: |
29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Imada S |
Year: |
2024 |
Journal: |
Nature |
Title: |
Short-term post-fast refeeding enhances intestinal stemness via polyamines. |
Volume: |
633 |
Issue: |
8031 |
Pages: |
895-904 |
|
•
•
•
•
•
|
Publication |
First Author: |
Signer RA |
Year: |
2014 |
Journal: |
Nature |
Title: |
Haematopoietic stem cells require a highly regulated protein synthesis rate. |
Volume: |
509 |
Issue: |
7498 |
Pages: |
49-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rodgers JT |
Year: |
2014 |
Journal: |
Nature |
Title: |
mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert). |
Volume: |
510 |
Issue: |
7505 |
Pages: |
393-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shrestha S |
Year: |
2015 |
Journal: |
Nat Immunol |
Title: |
Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. |
Volume: |
16 |
Issue: |
2 |
Pages: |
178-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu X |
Year: |
2024 |
Journal: |
Nat Commun |
Title: |
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness. |
Volume: |
15 |
Issue: |
1 |
Pages: |
10163 |
|
•
•
•
•
•
|
Publication |
First Author: |
Charbonnier LM |
Year: |
2015 |
Journal: |
Nat Immunol |
Title: |
Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling. |
Volume: |
16 |
Issue: |
11 |
Pages: |
1162-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hinden L |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function. |
Volume: |
13 |
Issue: |
1 |
Pages: |
1783 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang T |
Year: |
2016 |
Journal: |
Cell Mol Immunol |
Title: |
TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway. |
Volume: |
13 |
Issue: |
5 |
Pages: |
640-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Singh BK |
Year: |
2016 |
Journal: |
J Biol Chem |
Title: |
Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. |
Volume: |
291 |
Issue: |
1 |
Pages: |
198-214 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones I |
Year: |
2019 |
Journal: |
Biol Open |
Title: |
Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction. |
Volume: |
8 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lee PY |
Year: |
2017 |
Journal: |
Sci Immunol |
Title: |
The metabolic regulator mTORC1 controls terminal myeloid differentiation. |
Volume: |
2 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Gu Y |
Year: |
2011 |
Journal: |
Diabetes |
Title: |
Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size. |
Volume: |
60 |
Issue: |
3 |
Pages: |
827-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang H |
Year: |
2019 |
Journal: |
Cell Death Dis |
Title: |
AKT-dependent and -independent pathways mediate PTEN deletion-induced CNS axon regeneration. |
Volume: |
10 |
Issue: |
3 |
Pages: |
203 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fu X |
Year: |
2018 |
Journal: |
J Clin Invest |
Title: |
Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss. |
Volume: |
128 |
Issue: |
11 |
Pages: |
4938-4955 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van Nostrand JL |
Year: |
2020 |
Journal: |
Genes Dev |
Title: |
AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation. |
Volume: |
34 |
Issue: |
19-20 |
Pages: |
1330-1344 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu C |
Year: |
2021 |
Journal: |
Sci Adv |
Title: |
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt. |
Volume: |
7 |
Issue: |
41 |
Pages: |
eabg6262 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruegsegger C |
Year: |
2016 |
Journal: |
Neuron |
Title: |
Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. |
Volume: |
89 |
Issue: |
1 |
Pages: |
129-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Asrani K |
Year: |
2019 |
Journal: |
J Clin Invest |
Title: |
mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation. |
Volume: |
129 |
Issue: |
12 |
Pages: |
5584-5599 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGuire VA |
Year: |
2013 |
Journal: |
Mol Cell Biol |
Title: |
Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling. |
Volume: |
33 |
Issue: |
21 |
Pages: |
4152-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yousefi M |
Year: |
2018 |
Journal: |
Stem Cell Reports |
Title: |
Calorie Restriction Governs Intestinal Epithelial Regeneration through Cell-Autonomous Regulation of mTORC1 in Reserve Stem Cells. |
Volume: |
10 |
Issue: |
3 |
Pages: |
703-711 |
|
•
•
•
•
•
|
Publication |
First Author: |
Newton PT |
Year: |
2019 |
Journal: |
Nature |
Title: |
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate. |
Volume: |
567 |
Issue: |
7747 |
Pages: |
234-238 |
|
•
•
•
•
•
|
Publication |
First Author: |
Imanishi T |
Year: |
2019 |
Journal: |
Life Sci Alliance |
Title: |
Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function. |
Volume: |
2 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Martinez Calejman C |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
575 |
|
•
•
•
•
•
|
Publication |
First Author: |
Micevic G |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR. |
Volume: |
14 |
Issue: |
9 |
Pages: |
2180-2192 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiang H |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation. |
Volume: |
39 |
Issue: |
11 |
Pages: |
110943 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SG |
Year: |
2013 |
Journal: |
Mol Cell |
Title: |
Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex. |
Volume: |
49 |
Issue: |
1 |
Pages: |
172-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma L |
Year: |
2015 |
Journal: |
Mol Endocrinol |
Title: |
HDAC5-mTORC1 Interaction in Differential Regulation of Ghrelin and Nucleobindin 2 (NUCB2)/Nesfatin-1. |
Volume: |
29 |
Issue: |
11 |
Pages: |
1571-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ballif BA |
Year: |
2004 |
Journal: |
Mol Cell Proteomics |
Title: |
Phosphoproteomic analysis of the developing mouse brain. |
Volume: |
3 |
Issue: |
11 |
Pages: |
1093-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki N |
Year: |
2004 |
Journal: |
DNA Res |
Title: |
Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |
Volume: |
11 |
Issue: |
3 |
Pages: |
205-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Raynor JL |
Year: |
2020 |
Journal: |
J Exp Med |
Title: |
Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions. |
Volume: |
217 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Green RM |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Developmental nonlinearity drives phenotypic robustness. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1970 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adebayo Michael AO |
Year: |
2019 |
Journal: |
Cell Metab |
Title: |
Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations. |
Volume: |
29 |
Issue: |
5 |
Pages: |
1135-1150.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Festuccia WT |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide. |
Volume: |
9 |
Issue: |
4 |
Pages: |
e95432 |
|
•
•
•
•
•
|
Publication |
First Author: |
Porter SN |
Year: |
2016 |
Journal: |
Elife |
Title: |
Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang K |
Year: |
2022 |
Journal: |
Elife |
Title: |
Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria. |
Volume: |
11 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2023 |
Journal: |
Nature |
Title: |
Reprogramming tumour-associated macrophages to outcompete cancer cells. |
Volume: |
619 |
Issue: |
7970 |
Pages: |
616-623 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iezaki T |
Year: |
2018 |
Journal: |
Stem Cell Reports |
Title: |
Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
228-241 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson ME |
Year: |
2016 |
Journal: |
Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
Volume: |
537 |
Issue: |
7621 |
Pages: |
508-514 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Pereira M |
Year: |
2020 |
Journal: |
Elife |
Title: |
A trans-eQTL network regulates osteoclast multinucleation and bone mass. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Chen J |
Year: |
2014 |
Journal: |
PLoS Genet |
Title: |
WNT7B promotes bone formation in part through mTORC1. |
Volume: |
10 |
Issue: |
1 |
Pages: |
e1004145 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones I |
Year: |
2022 |
Journal: |
Dev Dyn |
Title: |
Reduced mTORC1-signaling in retinal ganglion cells leads to vascular retinopathy. |
Volume: |
251 |
Issue: |
2 |
Pages: |
321-335 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ramirez-Martinez A |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization. |
Volume: |
12 |
Issue: |
1 |
Pages: |
690 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blackshaw S |
Year: |
2004 |
Journal: |
PLoS Biol |
Title: |
Genomic analysis of mouse retinal development. |
Volume: |
2 |
Issue: |
9 |
Pages: |
E247 |
|
•
•
•
•
•
|