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Search results 4101 to 4200 out of 4302 for Acta2

0.057s
Type Details Score
GXD Expression
Probe: MGI:7285956
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7285958
Age: embryonic day 16.5
Image: 6 E16 SMG TAZ
Note: Nuclear localization of expression associated with Acta2 expression.
Specimen Label: 6 E16 SMG TAZ
Detected: true
Specimen Num: 10
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1668719
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7628743
Age: embryonic day 11.5
Image: 3E inset
Note: Coexpressed with Acta2 in the cells populating the mesenchyme surrounding aortic arch artery.
Specimen Label: 3E inset
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6393958
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1625520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7638765
Age: embryonic day 12.0
Note: Strong co-localization of expression with Acta2 in luminal region of Gfra1-expressing ring of cells.
Specimen Label: S2A E12.0, s2B
Detected: true
Specimen Num: 11
Allele
Name: actin alpha 2, smooth muscle, aorta; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
GXD Expression
Probe: MGI:6718483
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1787127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6718609
Age: postnatal day 0
Image: S13 WT
Note: Expression did not completely overlap with Acta2. Acta2 appeared to largely be excluded from Col1a1 expressing cells.
Specimen Label: S13 WT
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7518977
Assay Type: Immunohistochemistry
Annotation Date: 2023-08-18
Strength: Strong
Sex: Male
Emaps: EMAPS:1868727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7518996
Age: postnatal day 1
Note: High levels of expression persisted around testicular cords until P1. Co-expression with Acta2 in inner layers of mesenchyme.
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5882791
Assay Type: Immunohistochemistry
Annotation Date: 2017-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5882825
Age: postnatal
Note: Expressed in astrocytes with complex processes appeared to make contact with vessels. Not co-localized with Acta2 (pericytes).
Specimen Label: 3c
Detected: true
Specimen Num: 3
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Novartis Pharma AG
Allele Type: Targeted
Attribute String: Recombinase, RMCE-ready
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: transgene insertion 12, Pierre Chambon
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Allele
Name: transgene insertion 51, Pierre Chambon
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Allele
Name: transgene insertion, Pierre Chambon
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Allele
Name: transgene insertion 1, Raghu Kalluri
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: transgene insertion 1, Raghu Kalluri
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 1, Raghu Kalluri
Allele Type: Transgenic
Attribute String: Recombinase
Strain
Attribute String: transgenic, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, transgenic
Publication  
First Author: Uchida A
Year: 2020
Journal: Development
Title: Development and function of smooth muscle cells is modulated by Hic1 in mouse testis.
Volume: 147
Issue: 13
Publication
First Author: Song EC
Year: 2023
Journal: Cell Death Differ
Title: ΔNp63 maintains the fidelity of the myoepithelial cell lineage and directs cell differentiation programs in the murine salivary gland.
Volume: 30
Issue: 2
Pages: 515-526
Publication
First Author: Ai TJ
Year: 2018
Journal: Cell Death Differ
Title: Inhibition of neddylation by MLN4924 improves neointimal hyperplasia and promotes apoptosis of vascular smooth muscle cells through p53 and p62.
Volume: 25
Issue: 2
Pages: 319-329
Publication
First Author: Hochane M
Year: 2013
Journal: Endocrinology
Title: Parathyroid hormone-related protein is a mitogenic and a survival factor of mesangial cells from male mice: role of intracrine and paracrine pathways.
Volume: 154
Issue: 2
Pages: 853-64
Publication
First Author: Raison D
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Knockdown of parathyroid hormone related protein in smooth muscle cells alters renal hemodynamics but not blood pressure.
Volume: 305
Issue: 3
Pages: F333-42
Allele
Name: transgene insertion, Xiao Yang
Allele Type: Transgenic
Attribute String: Recombinase
Publication
First Author: Kim SK
Year: 2018
Journal: Hypertension
Title: Smooth Muscle Cell-Mineralocorticoid Receptor as a Mediator of Cardiovascular Stiffness With Aging.
Volume: 71
Issue: 4
Pages: 609-621
Publication
First Author: DuPont JJ
Year: 2016
Journal: JCI Insight
Title: Vascular mineralocorticoid receptor regulates microRNA-155 to promote vasoconstriction and rising blood pressure with aging.
Volume: 1
Issue: 14
Pages: e88942
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: LeBleu VS
Year: 2013
Journal: Nat Med
Title: Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis.
Volume: 19
Issue: 2
Pages: 227-31
Publication
First Author: Venning FA
Year: 2021
Journal: J Exp Clin Cancer Res
Title: Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer.
Volume: 40
Issue: 1
Pages: 175
Strain
Attribute String: congenic, mutant strain, transgenic
Genotype
Symbol: Nr3c2/Nr3c2 Tg(Acta2-cre/ERT2)#Pcn/?
Background: involves: 129S2/SvPas * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Moiseenko A
Year: 2017
Journal: Stem Cells
Title: Origin and characterization of alpha smooth muscle actin-positive cells during murine lung development.
Volume: 35
Issue: 6
Pages: 1566-1578
Publication
First Author: Au DT
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca2+ Signaling and Expression of Cytoskeleton-Related Proteins.
Volume: 38
Issue: 11
Pages: 2651-2664
Publication
First Author: Palumbo-Zerr K
Year: 2015
Journal: Nat Med
Title: Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis.
Volume: 21
Issue: 2
Pages: 150-8
Publication
First Author: Shvedova M
Year: 2019
Journal: J Cereb Blood Flow Metab
Title: cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice.
Volume: 39
Issue: 12
Pages: 2379-2391
Publication
First Author: Barrera-Chimal J
Year: 2017
Journal: J Am Soc Nephrol
Title: Benefit of Mineralocorticoid Receptor Antagonism in AKI: Role of Vascular Smooth Muscle Rac1.
Volume: 28
Issue: 4
Pages: 1216-1226
Publication
First Author: Irazoki A
Year: 2023
Journal: Nat Commun
Title: Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation.
Volume: 14
Issue: 1
Pages: 108
Publication
First Author: Wan S
Year: 2024
Journal: Cell Death Dis
Title: Activated hepatic stellate cell-derived Bmp-1 induces liver fibrosis via mediating hepatocyte epithelial-mesenchymal transition.
Volume: 15
Issue: 1
Pages: 41
Publication  
First Author: Liang ES
Year: 2018
Journal: J Mol Cell Cardiol
Title: Peptidyl-prolyl isomerase Pin1 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in ApoE-/- mice.
Volume: 114
Pages: 334-344
Publication
First Author: Qiao YN
Year: 2014
Journal: J Biol Chem
Title: Myosin phosphatase target subunit 1 (MYPT1) regulates the contraction and relaxation of vascular smooth muscle and maintains blood pressure.
Volume: 289
Issue: 32
Pages: 22512-23
Publication
First Author: Cao RY
Year: 2017
Journal: PLoS One
Title: Effects of p53-knockout in vascular smooth muscle cells on atherosclerosis in mice.
Volume: 12
Issue: 3
Pages: e0175061
Publication  
First Author: Moss ME
Year: 2018
Journal: Front Cardiovasc Med
Title: No Significant Role for Smooth Muscle Cell Mineralocorticoid Receptors in Atherosclerosis in the Apolipoprotein-E Knockout Mouse Model.
Volume: 5
Pages: 81
Strain
Attribute String: mutant strain, transgenic, congenic
Publication
First Author: Angelov SN
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms.
Volume: 37
Issue: 11
Pages: 2102-2113
Publication  
First Author: Zhang Y
Year: 2022
Journal: Front Pharmacol
Title: Deletion of Smooth Muscle Lethal Giant Larvae 1 Promotes Neointimal Hyperplasia in Mice.
Volume: 13
Pages: 834296
Publication  
First Author: Zhang T
Year: 2020
Journal: J Mol Cell Cardiol
Title: Lethal giant larvae 1 inhibits smooth muscle calcification via high mobility group box 1.
Volume: 142
Pages: 39-52
Publication  
First Author: Cooley JC
Year: 2023
Journal: JCI Insight
Title: Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis.
Volume: 8
Issue: 3
Publication
First Author: Liu S
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: HuR (Human Antigen R) Regulates the Contraction of Vascular Smooth Muscle and Maintains Blood Pressure.
Volume: 40
Issue: 4
Pages: 943-957
Publication
First Author: Zou Y
Year: 2018
Journal: Sci Rep
Title: Deletion of DGCR8 in VSMCs of adult mice results in loss of vascular reactivity, reduced blood pressure and neointima formation.
Volume: 8
Issue: 1
Pages: 1468
Publication
First Author: He WQ
Year: 2013
Journal: Gastroenterology
Title: Altered contractile phenotypes of intestinal smooth muscle in mice deficient in myosin phosphatase target subunit 1.
Volume: 144
Issue: 7
Pages: 1456-65, 1465.e1-5
Publication
First Author: Meng H
Year: 2021
Journal: iScience
Title: Synthetic VSMCs induce BBB disruption mediated by MYPT1 in ischemic stroke.
Volume: 24
Issue: 9
Pages: 103047
Publication
First Author: Huang J
Year: 2018
Journal: PLoS One
Title: Genetic approaches to identify pathological limitations in aortic smooth muscle contraction.
Volume: 13
Issue: 3
Pages: e0193769
Allele
Name: transgene insertion B6-1, Michael I Kotlikoff
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence, Reporter
Allele
Name: transgene insertion B7-5, Michael I Kotlikoff
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: transgene insertion B8-3, Michael I Kotlikoff
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: transgene insertion B34-4, Michael I Kotlikoff
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion B25-6, Michael I Kotlikoff
Allele Type: Transgenic
Attribute String: Reporter
Genotype
Symbol: Ppp1r12a/Ppp1r12a Tg(Acta2-cre)#Xya/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Acta2-cre/ERT2)#Pcn/? Tgfbr2/Tgfbr2 Tg(H2-K-Fosl2,-EGFP)13Wag/?
Background: B6.Cg-Tgfbr2 Tg(Acta2-cre/ERT2)#Pcn Tg(H2-K-Fosl2,-EGFP)13Wag
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Myl9/Myl9 Tg(Acta2-cre)#Xya/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Myl9/Myl9<+> Tg(Acta2-cre)#Xya/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ggps1/Ggps1 Tg(Acta2-cre)#Xya/?
Background: involves: CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Acta2-cre/ERT2)12Pcn/? Tg(CAG-cat,-lacZ)1Brn/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Acta2-cre/ERT2)51Pcn/? Tg(CAG-cat,-lacZ)1Brn/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Acta2-cre)1Rkl/?
Background: involves: 129X1/SvJ * FVB
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Sharma A
Year: 2023
Journal: J Cell Physiol
Title: CD14 is not required for carbon tetrachloride-induced hepatic inflammation and fibrosis with or without lipopolysaccharide challenge.
Volume: 238
Issue: 7
Pages: 1530-1541
Publication  
First Author: Mafanda EK
Year: 2019
Journal: Cytokine
Title: Essential role of suppressor of cytokine signaling 1 (SOCS1) in hepatocytes and macrophages in the regulation of liver fibrosis.
Volume: 124
Pages: 154501
Publication
First Author: Lindberg ME
Year: 2013
Journal: Biol Reprod
Title: Loss of CDH1 and Pten accelerates cellular invasiveness and angiogenesis in the mouse uterus.
Volume: 89
Issue: 1
Pages: 8
Publication  
First Author: Herring BP
Year: 2014
Journal: Vasc Cell
Title: Previously differentiated medial vascular smooth muscle cells contribute to neointima formation following vascular injury.
Volume: 6
Pages: 21
Publication
First Author: Toda N
Year: 2018
Journal: Nephrol Dial Transplant
Title: Deletion of connective tissue growth factor ameliorates peritoneal fibrosis by inhibiting angiogenesis and inflammation.
Volume: 33
Issue: 6
Pages: 943-953
Publication
First Author: Ferris LA
Year: 2021
Journal: Mol Cell Biochem
Title: Purine-rich element binding protein B attenuates the coactivator function of myocardin by a novel molecular mechanism of smooth muscle gene repression.
Volume: 476
Issue: 8
Pages: 2899-2916
Publication  
First Author: Azuma N
Year: 1998
Journal: Biochem J
Title: Cloning, expression and map assignment of chicken prosaposin.
Volume: 330 ( Pt 1)
Pages: 321-7
Publication
First Author: Warrington JP
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice.
Volume: 300
Issue: 3
Pages: H736-44
Publication
First Author: Zhao W
Year: 2022
Journal: Commun Biol
Title: MYPT1 reduction is a pathogenic factor of erectile dysfunction.
Volume: 5
Issue: 1
Pages: 744
Publication
First Author: McCurley A
Year: 2012
Journal: Nat Med
Title: Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors.
Volume: 18
Issue: 9
Pages: 1429-33
Publication  
First Author: Wei H
Year: 2017
Journal: J Am Heart Assoc
Title: Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling.
Volume: 6
Issue: 1
Publication
First Author: Rubin S
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: PHACTR-1 (Phosphatase and Actin Regulator 1) Deficiency in Either Endothelial or Smooth Muscle Cells Does Not Predispose Mice to Nonatherosclerotic Arteriopathies in 3 Transgenic Mice.
Volume: 42
Issue: 5
Pages: 597-609
Publication
First Author: Sheikh AQ
Year: 2014
Journal: Cell Rep
Title: Recapitulation of developing artery muscularization in pulmonary hypertension.
Volume: 6
Issue: 5
Pages: 809-17
Publication
First Author: Yang J
Year: 2017
Journal: Front Med
Title: Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis.
Volume: 11
Issue: 3
Pages: 403-409
Publication  
First Author: Zhang CH
Year: 2016
Journal: Nat Commun
Title: The molecular basis of the genesis of basal tone in internal anal sphincter.
Volume: 7
Pages: 11358
Publication  
First Author: Wang LN
Year: 2022
Journal: Microvasc Res
Title: Impaired vessel relaxation response and increased infarct size in smooth muscle cannabinoid receptor 1 knockout mice.
Volume: 139
Pages: 104263
Publication
First Author: Feng M
Year: 2019
Journal: J Cell Physiol
Title: The RyR-Cl(Ca) -VDCC axis contributes to spontaneous tone in urethral smooth muscle.
Volume: 234
Issue: 12
Pages: 23256-23267
Publication
First Author: Liu XM
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Ano1 regulates embryo transport by modulating intracellular calcium levels in oviduct smooth muscle.
Volume: 1870
Issue: 4
Pages: 167059
Publication
First Author: Qu M
Year: 2019
Journal: Biol Reprod
Title: Smooth muscle cell-specific TMEM16A deletion does not alter Ca2+ signaling, uterine contraction, gestation length, or litter size in mice†.
Volume: 101
Issue: 2
Pages: 318-327
Allele
Name: transgene insertion 6, Michael I Kotlikoff
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion B3-3, Michael I Kotlikoff
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: mutant strain, transgenic, congenic
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant strain, congenic
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Acta2-cre/ERT2)12Pcn/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Acta2-cre/ERT2)51Pcn/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Acta2-cre/ERT2)#Pcn/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Behrmann A
Year: 2023
Journal: Endocrinology
Title: Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR-/- Mice.
Volume: 165
Issue: 2
Publication  
First Author: Shin J
Year: 2023
Journal: Front Cardiovasc Med
Title: Smooth muscle cells-specific loss of OCT4 accelerates neointima formation after acute vascular injury.
Volume: 10
Pages: 1276945
Publication
First Author: McDaniel K
Year: 2017
Journal: J Biol Chem
Title: The let-7/Lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury.
Volume: 292
Issue: 27
Pages: 11336-11347
Publication
First Author: Gong L
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Fendrr involves in the pathogenesis of cardiac fibrosis via regulating miR-106b/SMAD3 axis.
Volume: 524
Issue: 1
Pages: 169-177